Content Posted in 2019
2-deoxy D-glucose treatment does not elicit a hair growth response in alopecia areata., John P Sundberg, Kathleen A Silva, Victoria E. Kennedy, John J Wilson, Nicholas E Gott, Beth A. Sundberg, and Derry C. Roopenian
3D extracellular matrix microenvironment in bioengineered tissue models of primary pediatric and adult brain tumors., Disha Sood, Min D Tang-Schomer, Dimitra Pouli, Craig Mizzoni, Nicole Raia, Albert Tai, Knarik Arkun, Julian Wu, Lauren D Black, Bjorn Scheffler, Irene Georgakoudi, Dennis A Steindler, and David L Kaplan
A Bayesian mixture model for the analysis of allelic expression in single cells., Kwangbom Choi, Narayanan Raghupathy, and Gary Churchill
Acarbose improves health and lifespan in aging HET3 mice., David E Harrison, Randy Strong, Silvestre Alavez, Clinton M Astle, John DiGiovanni, Elizabeth Fernandez, Kevin Flurkey, Michael Garratt, Jonathan A L Gelfond, Martin A Javors, Moshe Levi, Gordon J Lithgow, Francesca Macchiarini, James F Nelson, Stacey J Sukoff Rizzo, Thomas J Slaga, Timothy M Stearns, John Erby Wilkinson, and Richard A Miller
A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate., Simone Caielli, Diogo Troggian Veiga, Preetha Balasubramanian, Shruti Athale, Bojana Domic, Elise Murat, Romain Banchereau, Zhaohui Xu, Manjari Chandra, Cheng-Han Chung, Lynnette Walters, Jeanine Baisch, Tracey Wright, Marilynn Punaro, Lorien Nassi, Katie Stewart, Julie Fuller, Duygu Ucar, Hideki Ueno, Joseph Zhou, Jacques Banchereau, and Virginia Pascual
Acetate Promotes T Cell Effector Function during Glucose Restriction., Jing Qiu, Matteo Villa, David E Sanin, Michael D Buck, David O'Sullivan, Reagan Ching, Mai Matsushita, Katarzyna M Grzes, Frances Winkler, Chih-Hao Chang, Jonathan D Curtis, Ryan L Kyle, Nikki Van Teijlingen Bakker, Mauro Corrado, Fabian Haessler, Francesca Alfei, Joy Edwards-Hicks, Leonard B Maggi, Dietmar Zehn, Takeshi Egawa, Bertram Bengsch, Ramon I Klein Geltink, Thomas Jenuwein, Edward J Pearce, and Erika L Pearce
A computational method to aid the design and analysis of single cell RNA-seq experiments for cell type identification., Douglas Abrams, Parveen Kumar, Radha Krishna Murthy Karuturi, and Joshy George
A Contraction Stress Model of Hypertrophic Cardiomyopathy due to Sarcomere Mutations., Rachel Cohn, Ketan Thakar, Andre Lowe, Feria A Ladha, Anthony M Pettinato, Robert Romano, Emily Meredith, Yu-Sheng Chen, Katherine Atamanuk, Bryan D Huey, and J Travis Hinson
Activin type II receptor signaling in cardiac aging and heart failure., Jason D Roh, Ryan Hobson, Vinita Chaudhari, Pablo Quintero, Ashish Yeri, Mark Benson, Chunyang Xiao, Daniel Zlotoff, Vassilios Bezzerides, Nicholas Houstis, Colin Platt, Federico Damilano, Brian R Lindman, Sammy Elmariah, Michael Biersmith, Se-Jin Lee, Christine E Seidman, Jonathan G Seidman, Robert E Gerszten, Estelle Lach-Trifilieff, David J Glass, and Anthony Rosenzweig
A first genetic portrait of synaptonemal complex variation., Richard J Wang, Beth L Dumont, Peicheng Jing, and Bret A Payseur
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice., Bradford A Youngblood, Emily C Brock, John Leung, Rustom Falahati, Paul J Bryce, Jessica Bright, Jason Williams, Leonard D. Shultz, Dale L Greiner, Michael A Brehm, Christopher Bebbington, and Nenad Tomasevic
A large CRISPR-induced bystander mutation causes immune dysregulation., Dimitre R Simeonov, Alexander J Brandt, Alice Y Chan, Jessica T Cortez, Zhongmei Li, Jonathan M Woo, Youjin Lee, Claudia M B Carvalho, Alyssa C Indart, Theodore L Roth, James Zou, Andrew P May, James R Lupski, Mark S Anderson, F William Buaas, Daniel S Rokhsar, and Alexander Marson
Allele-specific RNA interference prevents neuropathy in Charcot-Marie-Tooth disease type 2D mouse models., Kathryn H Morelli, Laurie B Griffin, Nettie K Pyne, Lindsay M Wallace, Allison M Fowler, Stephanie N Oprescu, Ryuichi Takase, Na Wei, Rebecca Meyer-Schuman, Dattatreya Mellacheruvu, Jacob O Kitzman, Samuel G Kocen, Timothy J Hines, Emily L Spaulding, James R Lupski, Alexey Nesvizhskii, Pedro Mancias, Ian J Butler, Xiang-Lei Yang, Ya-Ming Hou, Anthony Antonellis, Scott Q Harper, and Robert W. Burgess
A longitudinal big data approach for precision health., Sophia Miryam Schüssler-Fiorenza Rose, Kévin Contrepois, Kegan J Moneghetti, Wenyu Zhou, Tejaswini Mishra, Samson Mataraso, Orit Dagan-Rosenfeld, Ariel B Ganz, Jessilyn Dunn, Daniel Hornburg, Shannon Rego, Dalia Perelman, Sara Ahadi, M Reza Sailani, Yanjiao Zhou, Shana Leopold, Jieming Chen, Melanie Ashland, Jeffrey W Christle, Monika Avina, Patricia Limcaoco, Camilo Ruiz, Marilyn Tan, Atul J Butte, George M. Weinstock, George M Slavich, Erica Sodergren Weinstock, Tracey L McLaughlin, Francois Haddad, and Michael P Snyder
Altered In Vivo Lipid Fluxes and Cell Dynamics in Subcutaneous Adipose Tissues Are Associated With the Unfavorable Pattern of Fat Distribution in Obese Adolescent Girls., Jessica Nouws, Mark Fitch, Mariana Mata, Nicola Santoro, Brittany Galuppo, Romy Kursawe, Deepak Narayan, Alla Vash-Margita, Bridget Pierpont, Gerald I Shulman, Marc Hellerstein, and Sonia Caprio
A mathematical model of combined CD8 T cell costimulation by 4-1BB (CD137) and OX40 (CD134) receptors., Anna Konstorum, Anthony T Vella, Adam J Adler, and Reinhard C Laubenbacher
A Mobile Prenatal Care App to Reduce In-Person Visits: Prospective Controlled Trial., Kathryn I Marko, Nihar Ganju, Jill M Krapf, Nancy D Gaba, James A Brown, Joshua J Benham, Julia Oh, Lorna M Richards, and Andrew C Meltzer
A mutation in mouse Krüppel-like factor 15 alters the gut microbiome and response to obesogenic diet., Karen L. Svenson, Lauren L Long, Steven L. Ciciotte, and Mark D Adams
An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells., Zhizhuo Zhang, Kern Rei Chng, Shreyas Lingadahalli, Zikai Chen, Mei Hui Liu, Huy Hoang Do, Shaojiang Cai, Nicola Rinaldi, Huay Mei Poh, Guoliang Li, Ying Ying Sung, Charlie L Heng, Leighton J Core, Si Kee Tan, Xiaoan Ruan, John T Lis, Manolis Kellis, Yijun Ruan, Wing-Kin Sung, and Edwin Cheung
An effective biomedical document classification scheme in support of biocuration: addressing class imbalance., Xiangying Jiang, Martin Ringwald, Judith A. Blake, Cecilia Arighi, Gongbo Zhang, and Hagit Shatkay
An integrative systems approach identifies novel candidates in Marfan syndrome-related pathophysiology., Raghu Bhushan, Lukas Altinbas, Marten Jäger, Marcin Zaradzki, Daniel Lehmann, Bernd Timmermann, Nicholas P Clayton, Yunxiang Zhu, Klaus Kallenbach, Georgios Kararigas, and Peter N Robinson
Annotation of gene product function from high-throughput studies using the Gene Ontology., Helen Attrill, Pascale Gaudet, Rachael P Huntley, Ruth C Lovering, Stacia R Engel, Sylvain Poux, Kimberly M Van Auken, George Georghiou, Marcus C Chibucos, Tanya Z Berardini, Valerie Wood, Harold J. Drabkin, Petra Fey, Penelope Garmiri, Midori A Harris, Tony Sawford, Leonore Reiser, Rebecca Tauber, Sabrina Toro, and Gene Ontology Consortium
An ontological foundation for ocular phenotypes and rare eye diseases., Panagiotis I Sergouniotis, Emmanuel Maxime, Dorothée Leroux, Annie Olry, Rachel Thompson, Ana Rath, Peter N Robinson, Hélène Dollfus, and ERN-EYE Ontology Study Group
Antibiotic collateral sensitivity is contingent on the repeatability of evolution., Daniel Nichol, Joseph Rutter, Christopher Bryant, Andrea M Hujer, Sai Lek, Mark D Adams, Peter Jeavons, Alexander R A Anderson, Robert A Bonomo, and Jacob G Scott
An update on risk assessment for familial and hereditary colorectal cancer., Emily A Edelman and Kate Reed
Assessment of Bones Deficient in Fibrillin-1 Microfibrils Reveals Pronounced Sex Differences., Lukas Altinbas, Nicole Bormann, Daniel Lehmann, Sarah Jeuthe, Dag Wulsten, Uwe Kornak, Peter N Robinson, Britt Wildemann, and Georgios Kararigas
Association of the Infant Gut Microbiome With Early Childhood Neurodevelopmental Outcomes: An Ancillary Study to the VDAART Randomized Clinical Trial., Joanne E Sordillo, Susan Korrick, Nancy Laranjo, Vincent Carey, George M. Weinstock, Diane R Gold, George O'Connor, Megan Sandel, Leonard B Bacharier, Avraham Beigelman, Robert Zeiger, Augusto A Litonjua, and Scott T Weiss
BiFET: sequencing Bias-free transcription factor Footprint Enrichment Test., Ahrim Youn, Eladio J Marquez, Nathan Lawlor, Michael L. Stitzel, and Duygu Ucar
B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes., Leire Egia-Mendikute, Berta Arpa, Estela Rosell-Mases, Marta Corral-Pujol, Jorge Carrascal, Jorge Carrillo, Conchi Mora, Harry Chapman, Anaïs Panosa, Marta Vives-Pi, Thomas Stratmann, David V. Serreze, and Joan Verdaguer
BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma., Rohit Sachdeva, Megan Wu, Kevin C Johnson, Hyunsoo Kim, Angela Celebre, Uswa Shahzad, Maya Srikanth Graham, John A Kessler, Jeffrey Chuang, Jason Karamchandani, Markus Bredel, Roel G W Verhaak, and Sunit Das
C57BL/6 Substrain Differences in Pharmacological Effects after Acute and Repeated Nicotine Administration., Lois S Akinola, Bryan Mckiver, Wisam Toma, Andy Z X Zhu, Rachel F Tyndale, Vivek Kumar, and M Imad Damaj
Cardiac phenotype in mouse models of systemic autoimmunity., Chandan Sanghera, Lok Man Wong, Mona Panahi, Amalia Sintou, Muneer G. Hasham, and Susanne Sattler
CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer., Zi-Ming Zhao, Susan E Yost, Katherine E Hutchinson, Sierra Min Li, Yate-Ching Yuan, Javad Noorbakhsh, Zheng Liu, Charles Warden, Radia M Johnson, Xiwei Wu, Jeffrey H Chuang, and Yuan Yuan
CD11c+ Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes., Adam M Sandor, Robin S Lindsay, Nathan Dyjack, Jennifer C Whitesell, Cydney Rios, Brenda J Bradley, Kathryn Haskins, David V. Serreze, Aron M Geurts, Yi-Guang Chen, Max A Seibold, Jordan Jacobelli, and Rachel S Friedman
Cell Specificity of Human Regulatory Annotations and Their Genetic Effects on Gene Expression., Arushi Varshney, Hadley VanRenterghem, Peter Orchard, Alan P Boyle, Michael L. Stitzel, Duygu Ucar, and Stephen C J Parker
Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis., Alexandra M Nicaise, Laura J Wagstaff, Cory M Willis, Carolyn Paisie, Harshpreet Chandok, Paul Robson, Valentina Fossati, Anna Williams, and Stephen J Crocker
Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice., Byron J Smith, Richard A Miller, Aaron C Ericsson, David E Harrison, Randy Strong, and Thomas M Schmidt
Characterization of acute TLR-7 agonist-induced hemorrhagic myocarditis in mice by multiparametric quantitative cardiac magnetic resonance imaging., Nicoleta Baxan, Angelos Papanikolaou, Isabelle Salles-Crawley, Amrit Lota, Rasheda Chowdhury, Olivier Dubois, Jane Branca, Muneer G. Hasham, Nadia Rosenthal, Sanjay K Prasad, Lan Zhao, Sian E Harding, and Susanne Sattler
Characterization of Mucosal Dysbiosis of Early Colonic Neoplasia., Bo-Young Hong, Takayasu Ideta, Bruno S Lemos, Yuichi Igarashi, Yuliana Tan, Michael DiSiena, Allen Mo, John W Birk, Faripour Forouhar, Thomas J Devers, George M. Weinstock, and Daniel W Rosenberg
Chemotherapy-induced oral mucositis is associated with detrimental bacterial dysbiosis., Bo-Young Hong, Takanori Sobue, Linda Choquette, Amanda K Dupuy, Angela Thompson, Joseph A Burleson, Andrew L Salner, Peter K Schauer, Pujan Joshi, Evan Fox, Dong-Guk Shin, George M. Weinstock, Linda D Strausbaugh, Anna Dongari-Bagtzoglou, Douglas E Peterson, and Patricia I Diaz
Circular ecDNA promotes accessible chromatin and high oncogene expression., Sihan Wu, Kristen M Turner, Nam Nguyen, Ramya Raviram, Marcella Erb, Jennifer Santini, Jens Luebeck, Utkrisht Rajkumar, Yarui Diao, Bin Li, Wenjing Zhang, Nathan Jameson, M Ryan Corces, Jeffrey M Granja, Xingqi Chen, Ceyda Coruh, Armen Abnousi, Jack Houston, Zhen Ye, Rong Hu, Miao Yu, Hoon Kim, Julie A Law, Roel G W Verhaak, Ming Hu, Frank B Furnari, Howard Y Chang, Bing Ren, Vineet Bafna, and Paul S Mischel
Cisplatin-resistant triple-negative breast cancer subtypes: multiple mechanisms of resistance., David P. Hill, Akeena Harper, Joan Malcolm, Monica McAndrews, Susan Mockus, Sara E. Patterson, Timothy Reynolds, Erich J Baker, Carol J Bult, Elissa J Chesler, and Judith A. Blake
Cleaning Genotype Data from Diversity Outbred Mice., Karl W Broman, Daniel M. Gatti, Karen L. Svenson, Śaunak Sen, and Gary Churchill
Clinical and Immunological Implications of Frameshift Mutations in Lung Cancer., Young Kwang Chae, Pedro Viveiros, Gilberto Lopes, Bhoomika Sukhadia, Muhammad Mubbashir Sheikh, Diana Saravia, Vaia Florou, Ethan S Sokol, Garrett M Frampton, Zachary R Chalmers, Siraj M Ali, Jeffrey S Ross, Sangmin Chang, Si Wang, Lauren Chiec, Ashkon Rahbari, Nisha Mohindra, Victoria Villaflor, Sang Ha Shin, Michael Oh, Jonathan Anker, Lee Chun Park, Victor G Wang, Jeffrey Chuang, and Wungki Park
Clinical Data: Sources and Types, Regulatory Constraints, Applications., Stanley C Ahalt, Christopher G Chute, Karamarie Fecho, Gustavo Glusman, Jennifer Hadlock, Casey Overby Taylor, Emily R Pfaff, Peter N Robinson, Harold Solbrig, Casey Ta, Nicholas Tatonetti, and Chunhua Weng
Clinical models of telehealth in genetics: A regional telegenetics landscape., Alissa B Terry, Amanda Wylie, Melissa Raspa, Beth Vogel, Kunal Sanghavi, Luba Djurdjinovic, Michele Caggana, and Joann Bodurtha
c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma., Kamini Singh, Jianan Lin, Yi Zhong, Antonija Burčul, Prathibha Mohan, Man Jiang, Liping Sun, Vladimir Yong-Gonzalez, Agnes Viale, Justin R Cross, Ronald C Hendrickson, Gunnar Rätsch, Zhengqing Ouyang, and Hans-Guido Wendel
Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model., Rintaro Ono, Takashi Watanabe, Eiryo Kawakami, Makoto Iwasaki, Mariko Tomizawa-Murasawa, Masashi Matsuda, Yuho Najima, Shinsuke Takagi, Saera Fujiki, Rumi Sato, Yoshiki Mochizuki, Hisahiro Yoshida, Kaoru Sato, Hiromasa Yabe, Shunichi Kato, Yoriko Saito, Shuichi Taniguchi, Leonard D. Shultz, Osamu Ohara, Masayuki Amagai, Haruhiko Koseki, and Fumihiko Ishikawa
Combined congenic mapping and nuclease-based gene targeting for studying allele-specific effects of Tnfrsf9 within the Idd9.3 autoimmune diabetes locus., Matthew H Forsberg, Bardees Foda, David V. Serreze, and Yi-Guang Chen
Comparative analysis of metabolome of rice seeds at three developmental stages using a recombinant inbred line population., Kang Li, Dehong Wang, Liang Gong, Yuanyuan Lyu, Hao Guo, Wei Chen, Cheng Jin, Xianqing Liu, Chuanying Fang, and Jie Luo
Compassion Fatigue, Euthanasia Stress, and Their Management in Laboratory Animal Research., Joseph T Newsome, Elizabeth A Clemmons, Dawn C Fitzhugh, Tracy L Gluckman, Michelle A Creamer-Hente, Laura J Tambrallo, and Temeri Wilder-Kofie
Complex Microbiome in Brain Abscess Revealed by Whole-Genome Culture-Independent and Culture-Based Sequencing., Jyun-Hong Lin, Zong-Yen Wu, Liang Gong, Chee-Hong Wong, Wen-Cheng Chao, Chun-Ming Yen, Ching-Ping Wang, Chia-Lin Wei, Yao-Ting Huang, and Po-Yu Liu
Composition and predictive functional analysis of bacterial communities inhabiting Chinese Cordyceps insight into conserved core microbiome., Fei Xia, Xin Zhou, Yan Liu, Yuling Li, Xiaohui Bai, and Xuanwei Zhou
Computational Processing and Quality Control of Hi-C, Capture Hi-C and Capture-C Data., Peter Hansen, Michael Gargano, Jochen Hecht, Jonas Ibn-Salem, Guy Karlebach, Johannes T Roehr, and Peter N Robinson
Connecting the molecular function of microRNAs to cell differentiation dynamics., Russell Posner and Reinhard Laubenbacher
Context-specific tumor suppression by PHF6., Jennifer J. Trowbridge
Creation of PDX-Bearing Humanized Mice to Study Immuno-oncology., Li-Chin Yao, Ken-Edwin Aryee, Mingshan Cheng, Pali Kaur, James G. Keck, and Michael A Brehm
Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts., Ela Elyada, Mohan Bolisetty, Pasquale Laise, William F Flynn, Elise T Courtois, Richard A Burkhart, Jonathan A Teinor, Pascal Belleau, Giulia Biffi, Matthew S Lucito, Santhosh Sivajothi, Todd D Armstrong, Dannielle D Engle, Kenneth H Yu, Yuan Hao, Christopher L Wolfgang, Youngkyu Park, Jonathan Preall, Elizabeth M Jaffee, Andrea Califano, Paul Robson, and David A Tuveson
Curating gene sets: challenges and opportunities for integrative analysis., Jason A. Bubier, David P. Hill, Gaurab Mukherjee, Timothy Reynolds, Erich J Baker, Alexander Berger, Jake Emerson, Judith A. Blake, and Elissa J Chesler
Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex., Richard K Babbs, Jacob A Beierle, Qiu T Ruan, Julia C Kelliher, Melanie M Chen, Ashley X Feng, Stacey L Kirkpatrick, Fabiola A Benitez, Fred A Rodriguez, Johanne J Pierre, Jeya Anandakumar, Vivek Kumar, Megan K Mulligan, and Camron D Bryant
Debutant iOS app and gene-disease complexities in clinical genomics and precision medicine., Zeeshan Ahmed, Saman Zeeshan, Ruoyun Xiong, and Bruce T Liang
De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes., Nirmal Vadgama, Alan Pittman, Michael Simpson, Niranjanan Nirmalananthan, Robin Murray, Takeo Yoshikawa, Peter De Rijk, Elliott Rees, George Kirov, Deborah Hughes, Tomas Fitzgerald, Mark Kristiansen, Kerra Pearce, Eliza Cerveira, Qihui Zhu, Chengsheng Zhang, Charles Lee, John Hardy, and Jamal Nasir
Detection and Classification of Novel Renal Histologic Phenotypes Using Deep Neural Networks., Susan Sheehan, Seamus Mawe, Rachel E Cianciolo, Ron Korstanje, and J Matthew Mahoney
Development and validation of a novel 29-plex Y-STR typing system for forensic application., Min Li, Wei Zhou, Yilun Zhang, Lei Huang, Xinjie Wang, Jun Wu, Meng Meng, Hongran Wang, Chengtao Li, and Yingnan Bian
Differential Effects of Rapamycin on Glucose Metabolism in Nine Inbred Strains., Peter C. Reifsnyder, Austen Te, and David E Harrison
Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis., SungHee Park, Mattia Brugiolo, Martin Akerman, Shipra Das, Laura M Urbanski, Adam Geier, Anil K Kesarwani, Martin Fan, Nathan Leclair, Kuan-Ting Lin, Leo Hu, Ian Hua, Joshy George, Senthil K Muthuswamy, Adrian R Krainer, and Olga Anczuków
Differential Hairless Mouse Strain-Specific Susceptibility to Skin Cancer and Sunburn., Anita Y Voigt, Michael Michaud, Kenneth Y Tsai, Julia Oh, and John P Sundberg
Doomed from the TERT? A Two-Stage Model of Tumorigenesis in IDH-Wild-Type Glioblastoma., Lucy F Stead and Roel G W Verhaak
Doxorubicin-Induced Cardiotoxicity in Collaborative Cross (CC) Mice Recapitulates Individual Cardiotoxicity in Humans., Caroline J Zeiss, Daniel M Gatti, Olga Toro-Salazar, Crystal Davis, Cathleen M Lutz, Francis Spinale, Timothy M Stearns, Milena B Furtado, and Gary A Churchill
Drug safety Africa: An overview of safety pharmacology & toxicology in South Africa., Brian D Guth, Anne F Grobler, Kendall S Frazier, Andrea Greiter-Wilke, Danuta Herzyk, Tertius A Hough, Asrar Ali Khan, Michael Markert, James D Smith, Karen L. Svenson, Sara Wells, and Michael K Pugsley
Early-life DNA methylation profiles are indicative of age-related transcriptome changes., Niran Hadad, Dustin R Masser, Laura Blanco-Berdugo, David R Stanford, and Willard M Freeman
Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis., Diane C Saunders, Marcela Brissova, Neil Phillips, Shristi Shrestha, John T Walker, Radhika Aramandla, Greg Poffenberger, David K Flaherty, Kevin P Weller, Julie Pelletier, Tracy Cooper, Matt T Goff, John Virostko, Alena Shostak, E Danielle Dean, Dale L Greiner, Leonard D. Shultz, Nripesh Prasad, Shawn E Levy, Robert H Carnahan, Chunhua Dai, Jean Sévigny, and Alvin C Powers
Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery., Baharak Bahmani, Mayuko Uehara, Farideh Ordikhani, Xiaofei Li, Liwei Jiang, Naima Banouni, Takaharu Ichimura, Vivek Kasinath, Siawosh K Eskandari, Nasim Annabi, Jonathan S Bromberg, Leonard D. Shultz, Dale L Greiner, and Reza Abdi
Editorial: Long Non-coding RNAs and Immunity., Grace J Kwon, Jorge Henao-Mejia, and Adam Williams
Effects of diet on the childhood gut microbiome and its implications for atopic dermatitis., Mahboobeh Mahdavinia, Heather E Rasmussen, Maresa Botha, Thi Dong Binh Tran, Jolice P Van den Berg, Erica Sodergren Weinstock, Erika Davis, Krista Engen, Claudia Gray, Nonhlanhla Lunjani, Carol Hlela, Nailliw Z Preite, Wisdom Basera, Lelani Hobane, Alexandra Watkins, Phillip Engen, Avumile Mankahla, Ben Gaunt, Facey Thomas, Mary C Tobin, Alan Landay, George M. Weinstock, Ali Keshavarzian, and Michael E Levin
Effects of IGF-1 isoforms on muscle growth and sarcopenia., Francesca Ascenzi, Laura Barberi, Gabriella Dobrowolny, Aline Villa Nova Bacurau, Carmine Nicoletti, Emanuele Rizzuto, Nadia Rosenthal, Bianca Maria Scicchitano, and Antonio Musarò
Elucidating cancer metabolic plasticity by coupling gene regulation with metabolic pathways., Dongya Jia, Mingyang Lu, Kwang Hwa Jung, Jun Hyoung Park, Linglin Yu, José N Onuchic, Benny Abraham Kaipparettu, and Herbert Levine
Enabling Global Clinical Collaborations on Identifiable Patient Data: The Minerva Initiative., Christoffer Nellåker, Fowzan S Alkuraya, Gareth Baynam, Raphael A Bernier, Francois P J Bernier, Vanessa Boulanger, Michael Brudno, Han G Brunner, Jill Clayton-Smith, Benjamin Cogné, Hugh J S Dawkins, Bert B A deVries, Sofia Douzgou, Tracy Dudding-Byth, Evan E Eichler, Michael Ferlaino, Karen Fieggen, Helen V Firth, David R FitzPatrick, Dylan Gration, Tudor Groza, Melissa Haendel, Nina Hallowell, Ada Hamosh, Jayne Hehir-Kwa, Marc-Phillip Hitz, Mark Hughes, Usha Kini, Tjitske Kleefstra, R Frank Kooy, Peter Krawitz, Sébastien Küry, Melissa Lees, Gholson J Lyon, Stanislas Lyonnet, Julien L Marcadier, Stephen Meyn, Veronika Moslerová, Juan M Politei, Cathryn C Poulton, F Lucy Raymond, Margot R F Reijnders, Peter N Robinson, Corrado Romano, Catherine M Rose, David C G Sainsbury, Lyn Schofield, Vernon R Sutton, Marek Turnovec, Anke Van Dijck, Hilde Van Esch, and Andrew O M Wilkie
Encoding Clinical Data with the Human Phenotype Ontology for Computational Differential Diagnostics., Sebastian Köhler, N Christine Øien, Orion J Buske, Tudor Groza, Julius O B Jacobsen, Craig McNamara, Nicole Vasilevsky, Leigh Carmody, J P Gourdine, Michael Gargano, Julie A McMurry, Daniel Danis, Christopher J Mungall, Damian Smedley, Melissa Haendel, and Peter N Robinson
Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways., Aziz Taghbalout, Menghan Du, Nathaniel L. Jillette, Wojciech Rosikiewicz, Abhijit Rath, Christopher D Heinen, Sheng Li, and Albert Cheng
Enhancing face validity of mouse models of Alzheimer's disease with natural genetic variation., Kristen D. Onos, Asli Uyar, Kelly J Keezer, Harriet M. Jackson, Christoph Preuss, Casey Acklin, Rita O'Rourke, Rebecca A Buchanan, Travis L Cossette, Stacey J Sukoff Rizzo, Ileana Soto, Gregory W. Carter, and Gareth R Howell
Enhancing the efficacy of glycolytic blockade in cancer cells via RAD51 inhibition., John J Wilson, Kin-Hoe Chow, Nathan J Labrie, Jane Branca, Thomas J. Sproule, Bryant R A Perkins, Elise E Wolf, Mauro W Costa, Grace Stafford, Christine Rosales, Kevin D Mills, Derry C. Roopenian, and Muneer G. Hasham
ENU-induced mutant allele of Dnah1, ferf1, causes abnormal sperm behavior and fertilization failure in mice., Jianjun Hu, Carl Lessard, Charles J Longstaff, Marilyn J. O'Brien, Kristina Palmer, Laura G Reinholdt, John J. Eppig, John Schimenti, and Mary Ann Handel
(Epi)genomic heterogeneity of pancreatic islet function and failure in type 2 diabetes., Nathan Lawlor and Michael L. Stitzel
Estimating heritability and genetic correlations from large health datasets in the absence of genetic data., Gengjie Jia, Yu Li, Hanxin Zhang, Ishanu Chattopadhyay, Anders Boeck Jensen, David R Blair, Lea Davis, Peter N Robinson, Torsten Dahlén, Søren Brunak, Mikael Benson, Gustaf Edgren, Nancy J Cox, Xin Gao, and Andrey Rzhetsky
Evaluating gene fusions in solid tumors - clinical experience using an RNA based 53 gene next-generation sequencing panel., Pavalan Selvam, Kevin Kelly, Andrew N Hesse, Daniel Spitzer, and Honey V Reddi
Evaluating heating methods for mice., Jasmine Delany, Michelle Creamer-Hente, Daniel Vanbuskirk, Mingshan Cheng, and Kyle Draheim
Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis., Jethro Johnson, Daniel Spakowicz, Bo-Young Hong, Lauren M Petersen, Patrick Demkowicz, Lei Chen, Shana Leopold, Blake M Hanson, Hanako O Agresta, Mark Gerstein, Erica Sodergren, and George M. Weinstock
Evaluation of INSeq To Identify Genes Essential for, Ramamoorthy Sivakumar, Jothi Ranjani, Udayakumar S Vishnu, Sathyanarayanan Jayashree, Gabriel L Lozano, Jessica Miles, Nichole A Broderick, Changhui Guan, Paramasamy Gunasekaran, Jo Handelsman, and Jeyaprakash Rajendhran
Evolutionary dynamics of residual disease in human glioblastoma., I Spiteri, G Caravagna, G D Cresswell, A Vatsiou, D Nichol, A Acar, L Ermini, K Chkhaidze, B Werner, R Mair, E Brognaro, Roel G W Verhaak, G Sanguinetti, S G M Piccirillo, C Watts, and A Sottoriva
Exercise prevents obesity-induced cognitive decline and white matter damage in mice., Leah C. Graham, Weronika Grabowska, Yoona Chun, Shannon L Risacher, Vivek M. Philip, Andrew J Saykin, Alzheimer's Disease Neuroimaging Initiative, Stacey J Sukoff Rizzo, and Gareth R Howell
Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources., Sebastian Köhler, Leigh Carmody, Nicole Vasilevsky, Julius O B Jacobsen, Daniel Danis, Jean-Philippe Gourdine, Michael Gargano, Nomi L Harris, Nicolas Matentzoglu, Julie A McMurry, David Osumi-Sutherland, Valentina Cipriani, James P Balhoff, Tom Conlin, Hannah Blau, Gareth Baynam, Richard Palmer, Dylan Gratian, Hugh Dawkins, Michael Segal, Anna C Jansen, Ahmed Muaz, Willie H Chang, Jenna Bergerson, Stanley J F Laulederkind, Zafer Yüksel, Sergi Beltran, Alexandra F Freeman, Panagiotis I Sergouniotis, Daniel Durkin, Andrea L Storm, Marc Hanauer, Michael Brudno, Susan M. Bello, Murat Sincan, Kayli Rageth, Matthew T Wheeler, Renske Oegema, Halima Lourghi, Maria G Della Rocca, Rachel Thompson, Francisco Castellanos, James Priest, Charlotte Cunningham-Rundles, Ayushi Hegde, Ruth C Lovering, Catherine Hajek, Annie Olry, Luigi Notarangelo, Morgan Similuk, Xingmin A Zhang, David Gómez-Andrés, Hanns Lochmüller, Hélène Dollfus, Sergio Rosenzweig, Shruti Marwaha, Ana Rath, Kathleen Sullivan, Cynthia Smith, Joshua D Milner, Dorothée Leroux, Cornelius F Boerkoel, Amy Klion, Melody C Carter, Tudor Groza, Damian Smedley, Melissa A Haendel, Chris Mungall, and Peter N Robinson
Extrachromosomal oncogene amplification in tumour pathogenesis and evolution., Roel G W Verhaak, Vineet Bafna, and Paul S Mischel
Factors that influence response classifications in chemotherapy treated patient-derived xenografts (PDX)., Joan Malcolm, Timothy M Stearns, Susan Airhart, Joel H. Graber, and Carol J Bult
Family health history and genetic services-the East Baltimore community stakeholder interview project., Kunal Sanghavi, Ivy Moses, DuWade Moses, Adelaide Gordon, Linda Chyr, and Joann Bodurtha
Fibronectin-conjugated thermoresponsive nanobridges generate three dimensional human pluripotent stem cell cultures for differentiation towards the neural lineages., Linda Harkness, Xiaoli Chen, Zhongfan Jia, Anthony M Davies, Michael Monteiro, Peter Gray, and Martin Pera
Film interface for drug testing for delivery to cells in culture and in the brain., Min D Tang-Schomer, David L Kaplan, and Michael J Whalen
Fostering bioinformatics education through skill development of professors: Big Genomic Data Skills Training for Professors., Yingqian Ada Zhan, Charles Gregory Wray, Sandeep Namburi, Spencer T Glantz, Reinhard Laubenbacher, and Jeffrey H Chuang
Functional interrogation of Lynch syndrome-associated MSH2 missense variants via CRISPR-Cas9 gene editing in human embryonic stem cells., Abhijit Rath, Akriti Mishra, Victoria Duque Ferreira, Chaoran Hu, Gregory Omerza, Kevin Kelly, Andrew N Hesse, Honey V Reddi, James P Grady, and Christopher D Heinen
Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells., Elvin Wagenblast, Maria Azkanaz, Sabrina A Smith, Lorien Shakib, Jessica L McLeod, Gabriela Krivdova, Joana Araújo, Leonard D. Shultz, Olga I Gan, John E Dick, and Eric R Lechman
Functional rescue in a mouse model of congenital muscular dystrophy with megaconial myopathy., Ambreen A Sayed-Zahid, Roger B Sher, Stacey J Sukoff Rizzo, Laura C. Anderson, Kathryn E Patenaude, and Gregory A. Cox
Gain of function p.E138A alteration in Card14 leads to psoriasiform skin inflammation and implicates genetic modifiers in disease severity., John P Sundberg, C Herbert Pratt, Kathleen A Silva, Victoria E. Kennedy, Wenning Qin, Timothy M Stearns, Jacqueline Frost, Beth A. Sundberg, and Anne M Bowcock
Gene-by-environment interactions in Alzheimer's disease and Parkinson's disease., Amy R Dunn, Kristen M S O'Connell, and Catherine C Kaczorowski
Gene loci associated with insulin secretion in islets from non-diabetic mice., Mark P Keller, Mary E Rabaglia, Kathryn L Schueler, Donnie S Stapleton, Daniel M Gatti, Matthew J Vincent, Kelly A Mitok, Ziyue Wang, Takanao Ishimura, Shane P Simonett, Christopher H Emfinger, Rahul Das, Tim Beck, Christina Kendziorski, Karl W Broman, Brian S Yandell, Gary A Churchill, and Alan D Attie
Gene Ontology Causal Activity Modeling (GO-CAM) moves beyond GO annotations to structured descriptions of biological functions and systems., Paul D Thomas, David P. Hill, Huaiyu Mi, David Osumi-Sutherland, Kimberly Van Auken, Seth Carbon, James P Balhoff, Laurent-Philippe Albou, Benjamin Good, Pascale Gaudet, Suzanna E Lewis, and Christopher J Mungall
Generation of Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells., Hideyuki Oguro
Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease., Kristen M S O'Connell, Andrew R Ouellette, Sarah M Neuner, Amy R Dunn, and Catherine Kaczorowski
Genetic determinants of gut microbiota composition and bile acid profiles in mice., Julia H Kemis, Vanessa Linke, Kelsey L Barrett, Frederick J Boehm, Lindsay L Traeger, Mark P Keller, Mary E Rabaglia, Kathryn L Schueler, Donald S Stapleton, Daniel M Gatti, Gary A Churchill, Daniel Amador-Noguez, Jason D Russell, Brian S Yandell, Karl W Broman, Joshua J Coon, Alan D Attie, and Federico E Rey
Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response., Jill M. Recla, Jason A. Bubier, Daniel M Gatti, Jennifer L Ryan, Katie H Long, Raymond F. Robledo, Nicole C Glidden, Guoqiang Hou, Gary Churchill, Richard S. Maser, Zhong-Wei Zhang, Erin E Young, Elissa J Chesler, and Carol J Bult
Genetic variation in thyroid folliculogenesis influences susceptibility to hypothyroidism-induced hearing impairment., Amanda H Mortensen, Qing Fang, Michelle T Fleming, Thomas J Jones, Alexandre Z Daly, Kenneth R. Johnson, and Sally A Camper
Genome assembly and gene expression in the American black bear provides new insights into the renal response to hibernation., Anuj Srivastava, Vishal Kumar Sarsani, Ian Fiddes, Susan Sheehan, Rita L Seger, Mary Barter, Selena Neptune-Bear, Charlotte Lindqvist, and Ron Korstanje
Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features., Joyce E Karlinsey, Taylor A Stepien, Matthew Mayho, Larissa A Singletary, Lacey K Bingham-Ramos, Michael A Brehm, Dale L Greiner, Leonard D. Shultz, Larry A Gallagher, Matt Bawn, Robert A Kingsley, Stephen J Libby, and Ferric C Fang
Genomic architecture of Shh-dependent cochlear morphogenesis., Victor Muthu, Alex M Rohacek, Yao Yao, Staci M Rakowiecki, Alexander S Brown, Ying-Tao Zhao, James Meyers, Kyoung-Jae Won, Shweta Ramdas, Christopher D Brown, Kevin A Peterson, and Douglas J Epstein
Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines., Xing Yi Woo, Anuj Srivastava, Joel H Graber, Vinod Yadav, Vishal Kumar Sarsani, Allen K. Simons, Glen L Beane, Stephen C. Grubb, Guruprasad Ananda, Rangjiao Liu, Grace Stafford, Jeffrey Chuang, Susan Airhart, Radha Krishna Murthy Karuturi, Joshy George, and Carol J Bult
Genomic inversions and GOLGA core duplicons underlie disease instability at the 15q25 locus., Flavia A M Maggiolini, Stuart Cantsilieris, Pietro D'Addabbo, Michele Manganelli, Bradley P Coe, Beth L Dumont, Ashley D Sanders, Andy Wing Chun Pang, Mitchell R Vollger, Orazio Palumbo, Pietro Palumbo, Maria Accadia, Massimo Carella, Evan E Eichler, and Francesca Antonacci
Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in, Elisabeth A Marnik, J Heath Fuqua, Catherine S Sharp, Jesse D Rochester, Emily L Xu, Sarah E Holbrook, and Dustin L Updike
Glycine supplementation extends lifespan of male and female mice., Richard A Miller, David E Harrison, Clinton Michael Astle, Molly A. Bogue, Joel Brind, Elizabeth Fernandez, Kevin Flurkey, Martin Javors, Warren Ladiges, Christiaan Leeuwenburgh, Francesca Macchiarini, James Nelson, Alexey G Ryazanov, Jessica Snyder, Timothy M Stearns, Douglas E Vaughan, and Randy Strong
GOPHER: Generator Of Probes for capture Hi-C Experiments at high Resolution., Peter Hansen, Salaheddine Ali, Hannah Blau, Daniel Danis, Jochen Hecht, Uwe Kornak, Darío G Lupiáñez, Stefan Mundlos, Robin Steinhaus, and Peter N Robinson
GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity., Abby Tadenev, Anil Akturk, Nicholas Devanney, Pranav Dinesh Mathur, Anna M Clark, Jun Yang, and Basile Tarchini
Growth differentiation factor 11 locally controls anterior-posterior patterning of the axial skeleton., Joonho Suh, Je-Hyun Eom, Na-Kyung Kim, Kyung Mi Woo, Jeong-Hwa Baek, Hyun-Mo Ryoo, Se-Jin Lee, and Yun-Sil Lee
Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine., Sarah M Neuner, Sarah E Heuer, Matthew J Huentelman, Kristen M S O'Connell, and Catherine C Kaczorowski
Hepsin-mediated Processing of Uromodulin is Crucial for Salt-sensitivity and Thick Ascending Limb Homeostasis., Eric Olinger, Jennifer Lake, Susan Sheehan, Guglielmo Schiano, Tomoaki Takata, Natsuko Tokonami, Huguette Debaix, Francesco Consolato, Luca Rampoldi, Ron Korstanje, and Olivier Devuyst
High-Diversity Mouse Populations for Complex Traits., Michael C Saul, Vivek M. Philip, Laura G Reinholdt, Center for Systems Neurogenetics of Addiction, and Elissa J Chesler
Histone methyltransferase PRDM9 is not essential for meiosis in male mice., Ondrej Mihola, Florencia Pratto, Kevin Brick, Eliska Linhartova, Tatyana Kobets, Petr Flachs, Christopher L. Baker, Radislav Sedlacek, Kenneth Paigen, Petko M. Petkov, R Daniel Camerini-Otero, and Zdenek Trachtulec
HSP90 Inhibitor, NVP-AUY922, Improves Myelination in Vitro and Supports the Maintenance of Myelinated Axons in Neuropathic Mice., Vinita G Chittoor-Vinod, Hannah Bazick, Adrian G Todd, Darin Falk, Kathryn H Morelli, Robert W. Burgess, Thomas C Foster, and Lucia Notterpek
Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1., Melissa A Gawron, Mark Duval, Claudia Carbone, Smita Jaiswal, Aaron Wallace, Joseph C Martin, Ann Dauphin, Michael A Brehm, Dale L Greiner, Leonard D. Shultz, Jeremy Luban, and Lisa A Cavacini
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain., Devon S Svoboda, M Inmaculada Barrasa, Jian Shu, Rosalie Rietjens, Shupei Zhang, Maya Mitalipova, Peter Berube, Dongdong Fu, Leonard D. Shultz, George W Bell, and Rudolf Jaenisch
Humanized immune system mouse models: progress, challenges and opportunities., Todd M Allen, Michael A Brehm, Sandra Bridges, Stacy Ferguson, Priti Kumar, Oleg Mirochnitchenko, Karolina Palucka, Roberta Pelanda, Brigitte Sanders-Beer, Leonard D. Shultz, Lishan Su, and Mercy PrabhuDas
Humanized mouse models of immunological diseases and precision medicine., Leonard D. Shultz, James Keck, Lisa M. Burzenski, Sonal Jangalwe, Shantashri Vaidya, Dale L Greiner, and Michael A Brehm
Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice., Masashi Matsuda, Rintaro Ono, Tomonori Iyoda, Takaho Endo, Makoto Iwasaki, Mariko Tomizawa-Murasawa, Yoriko Saito, Akiko Kaneko, Kanako Shimizu, Daisuke Yamada, Narumi Ogonuki, Takashi Watanabe, Manabu Nakayama, Yoko Koseki, Fuyuko Kezuka-Shiotani, Takanori Hasegawa, Hiromasa Yabe, Shunichi Kato, Atsuo Ogura, Leonard D. Shultz, Osamu Ohara, Masaru Taniguchi, Haruhiko Koseki, Shin-Ichiro Fujii, and Fumihiko Ishikawa
Hyaline Arteriolosclerosis in 30 Strains of Aged Inbred Mice., Timothy K Cooper, Kathleen A Silva, Victoria E. Kennedy, Sarah Alghamdi, Robert Hoehndorf, Beth A. Sundberg, Paul N Schofield, and John P Sundberg
Hybrid Sterility with Meiotic Metaphase Arrest in Intersubspecific Mouse Crosses., Risako Nishino, Sabrina Petri, Mary Ann Handel, Tetsuo Kunieda, and Yasuhiro Fujiwara
Identification of Acer2 as a First Susceptibility Gene for Lithium-Induced Nephrogenic Diabetes Insipidus in Mice, Theun de Groot, Lena K Ebert, Birgitte Mønster Christensen, Karolina Andralojc, Lydie Cheval, Alain Doucet, Cungui Mao, Ruben Baumgarten, Benjamin E. Low, Roger Sandhoff, Michael V. Wiles, Peter M T Deen, and Ron Korstanje
Identification of a Functional Non-coding Variant in the GABA, Megan K Mulligan, Timothy Abreo, Sarah M Neuner, Cory Parks, Christine E Watkins, M Trevor Houseal, Thomas M Shapaker, Michael Hook, Haiyan Tan, Xusheng Wang, Jesse Ingels, Junmin Peng, Lu Lu, Catherine Kaczorowski, Camron D Bryant, Gregg E Homanics, and Robert W Williams
Identification of a novel gene regulating amygdala-mediated fear extinction., Ozge Gunduz-Cinar, Emma Brockway, Lauren Lederle, Troy Wilcox, Lindsay R Halladay, Ying Ding, Hyunjung Oh, Erica F Busch, Katie Kaugars, Shaun Flynn, Aaron Limoges, Olena Bukalo, Kathryn P MacPherson, Sophie Masneuf, Courtney Pinard, Etienne Sibille, Elissa J Chesler, and Andrew Holmes
Identification of a T follicular helper cell subset that drives anaphylactic IgE., Uthaman Gowthaman, Jennifer S Chen, Biyan Zhang, William F Flynn, Yisi Lu, Wenzhi Song, Julie Joseph, Jake A Gertie, Lan Xu, Magalie A Collet, Jessica D S Grassmann, Tregony Simoneau, David Chiang, M Cecilia Berin, Joseph E Craft, Jason S Weinstein, Adam Williams, and Stephanie C Eisenbarth
Identification of a tumor-specific allo-HLA-restricted γδTCR., G J J Kierkels, W Scheper, A D Meringa, I Johanna, D X Beringer, A Janssen, M Schiffler, T Aarts-Riemens, L Kramer, T Straetemans, S Heijhuurs, J H W Leusen, E San José, K Fuchs, M Griffioen, J H Falkenburg, L Bongiovanni, A de Bruin, D Vargas-Diaz, M Altelaar, A J R Heck, Leonard D. Shultz, F Ishikawa, M I Nishimura, Z Sebestyén, and J Kuball
Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF., Manju Sharma, Anuj Srivastava, Heather Fairfield, David E. Bergstrom, William F Flynn, and Robert E Braun
Identification of Genomic and Molecular Traits that Present Therapeutic Vulnerability to HGF-targeted therapy in Glioblastoma., Jason K Sa, Sung Heon Kim, Jin-Ku Lee, Hee Jin Cho, Yong Jae Shin, Hyemi Shin, Harim Koo, Donggeon Kim, Mijeong Lee, Wonyoung Kang, Sung Hee Hong, Jung Yong Kim, Young-Whan Park, Seong-Won Song, Song-Jae Lee, Kyeung Min Joo, and Do-Hyun Nam
Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model., Sarah M Neuner, Sarah E Heuer, Ji-Gang Zhang, Vivek M. Philip, and Catherine Kaczorowski
Identifying and ranking potential driver genes of Alzheimer's disease using multiview evidence aggregation., Sumit Mukherjee, Thanneer M Perumal, Kenneth Daily, Solveig K Sieberts, Larsson Omberg, Christoph Preuss, Gregory W. Carter, Lara M Mangravite, and Benjamin A Logsdon
IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α, Dong Liu, Xiangyun Yin, Sam J Olyha, Manuela Sales L Nascimento, Pei Chen, Theresa White, Uthaman Gowthaman, Tingting Zhang, Jake A Gertie, Biyan Zhang, Lan Xu, Marina Yurieva, Lesley Devine, Adam Williams, and Stephanie C Eisenbarth
Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways., Xiang Nan, Jiang Wang, Hao Cheng, Zheng Yin, Jianting Sheng, Bensheng Qiu, Ching C Lau, Jason T Yustein, Hong Zhao, and Stephen T C Wong
Immune cells for microbiota surveillance., Julia Oh and Derya Unutmaz
Improving homology-directed repair efficiency in human stem cells., William C Skarnes, Enrica Pellegrino, and Justin A McDonough
Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C., Larisa Kavetsky, Kayla K Green, Bridget R Boyle, Fawad A K Yousufzai, Zachary M Padron, Sierra E Melli, Victoria L Kuhnel, Harriet M. Jackson, Rosa E Blanco, Gareth R Howell, and Ileana Soto
Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma., Pete A. Williams, Catherine E. Braine, Krishnakumar Kizhatil, Nicole E Foxworth, Nicholas G Tolman, Jeffrey M. Harder, Rebecca A Scott, Gregory L Sousa, Alyssa Panitch, Gareth R Howell, and Simon W M John
Inhibition of Tissue-Nonspecific Alkaline Phosphatase Attenuates Ectopic Mineralization in the Abcc6, Qiaoli Li, Jianhe Huang, Anthony B Pinkerton, Jose Luis Millan, Bertrand D van Zelst, Michael A Levine, John P Sundberg, and Jouni Uitto
Integrated Analysis of Clinical and Microbiome Risk Factors Associated with the Development of Oral Candidiasis during Cancer Chemotherapy., Patricia I Diaz, Bo-Young Hong, Amanda K Dupuy, Linda Choquette, Angela Thompson, Andrew L Salner, Peter K Schauer, Upendra Hegde, Joseph A Burleson, Linda D Strausbaugh, Douglas E Peterson, and Anna Dongari-Bagtzoglou
Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species., Jason A. Bubier, George L Sutphin, Timothy J Reynolds, Ron Korstanje, Axis Fuksman-Kumpa, Erich J Baker, Michael A Langston, and Elissa J Chesler
Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation., Ashley E Ciecko, Bardees Foda, Jennifer Y Barr, Sheela Ramanathan, Mark A Atkinson, David V. Serreze, Aron M Geurts, Scott M Lieberman, and Yi-Guang Chen
Interplay between dendritic cells and cancer cells., Jan Martinek, Te-Chia Wu, Diana Cadena, Jacques Banchereau, and Karolina Palucka
Intrinsic planar polarity mechanisms influence the position-dependent regulation of synapse properties in inner hair cells., Philippe Jean, Özge Demet Özçete, Basile Tarchini, and Tobias Moser
iPreP is a three-dimensional nanofibrillar cellulose hydrogel platform for long-term ex vivo preservation of human islets., Yi-Ju Chen, Taiji Yamazoe, Karla F Leavens, Fabian L Cardenas-Diaz, Andrei Georgescu, Dongeun Huh, Paul Gadue, and Ben Z Stanger
Knockdown of heterochromatin protein 1 binding protein 3 recapitulates phenotypic, cellular, and molecular features of aging., Sarah M Neuner, Shengyuan Ding, and Catherine C Kaczorowski
Know Your Model: How essential is that essential gene?, Susan M. Bello, Melissa L. Berry, and Cynthia L Smith
Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression., Michael A Brehm, Laurie L Kenney, Michael V. Wiles, Benjamin E. Low, Roland M Tisch, Lisa M. Burzenski, Christian Mueller, Dale L Greiner, and Leonard D. Shultz
Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis., Leslie O Goodwin, Erik Splinter, Tiffany Leidy-Davis, Rachel Urban, Hao He, Robert E Braun, Elissa J Chesler, Vivek Kumar, Max van Min, Juliet Ndukum, Vivek M. Philip, Laura G Reinholdt, Karen L. Svenson, Jacqueline K White, Michael Sasner, Cathleen Lutz, and Stephen A. Murray
Linked-read Sequencing Analysis Reveals Tumor-specific Genome Variation Landscapes in Neurofibromatosis Type 2 (NF2) Patients., Daniel S Roberts, Rahul Maurya, Yuka Takemon, Jeremie Vitte, Liang Gong, Juanjuan Zhao, Chee-Hong Wong, William Slattery, Kevin A Peng, Gregory Lekovic, Marc S Schwartz, Ketan Bulsara, Chew Yee Ngan, Marco Giovannini, and Chia-Lin Wei
Liriodendron genome sheds light on angiosperm phylogeny and species-pair differentiation., Jinhui Chen, Zhaodong Hao, Xuanmin Guang, Chenxi Zhao, Pengkai Wang, Liangjiao Xue, Qihui Zhu, Linfeng Yang, Yu Sheng, Yanwei Zhou, Haibin Xu, Hongqing Xie, Xiaofei Long, Jin Zhang, Zhangrong Wang, Mingming Shi, Ye Lu, Siqin Liu, Lanhua Guan, Qianhua Zhu, Liming Yang, Song Ge, Tielong Cheng, Thomas Laux, Qiang Gao, Ye Peng, Na Liu, Sihai Yang, and Jisen Shi
LISA: Accurate reconstruction of cell trajectory and pseudo-time for massive single cell RNA-seq data., Yang Chen, Yuping Zhang, and Zhengqing Ouyang
Longitudinal molecular trajectories of diffuse glioma in adults., Floris P Barthel, Kevin C Johnson, Frederick S Varn, Anzhela D Moskalik, Georgette Tanner, Emre Kocakavuk, Kevin J Anderson, Olajide Abiola, Kenneth Aldape, Kristin D Alfaro, Donat Alpar, Samirkumar B Amin, David M Ashley, Pratiti Bandopadhayay, Jill S Barnholtz-Sloan, Rameen Beroukhim, Christoph Bock, Priscilla K Brastianos, Daniel J Brat, Andrew R Brodbelt, Alexander F Bruns, Ketan R Bulsara, Aruna Chakrabarty, Arnab Chakravarti, Jeffrey Chuang, Elizabeth B Claus, Elizabeth J Cochran, Jennifer Connelly, Joseph F Costello, Gaetano Finocchiaro, Michael N Fletcher, Pim J French, Hui K Gan, Mark R Gilbert, Peter V Gould, Matthew R Grimmer, Antonio Iavarone, Azzam Ismail, Michael D Jenkinson, Mustafa Khasraw, Hoon Kim, Mathilde C M Kouwenhoven, Peter S LaViolette, Meihong Li, Peter Lichter, Keith L Ligon, Allison K Lowman, Tathiane M Malta, Tali Mazor, Kerrie L McDonald, Annette M Molinaro, Do-Hyun Nam, Naema Nayyar, Ho Keung Ng, Chew Yee Ngan, Simone P Niclou, Johanna M Niers, Houtan Noushmehr, Javad Noorbakhsh, D Ryan Ormond, Chul-Kee Park, Laila M Poisson, Raul Rabadan, Bernhard Radlwimmer, Ganesh Rao, Guido Reifenberger, Jason K Sa, Michael Schuster, Brian L Shaw, Susan C Short, Peter A Sillevis Smitt, Andrew E Sloan, Marion Smits, Hiromichi Suzuki, Ghazaleh Tabatabai, Erwin G Van Meir, Colin Watts, Michael Weller, Pieter Wesseling, Bart A Westerman, Georg Widhalm, Adelheid Woehrer, W K Alfred Yung, Gelareh Zadeh, Jason T Huse, John F De Groot, Lucy F Stead, Roel G W Verhaak, and The GLASS Consortium
Longitudinal multi-omics of host-microbe dynamics in prediabetes., Wenyu Zhou, M Reza Sailani, Kévin Contrepois, Yanjiao Zhou, Sara Ahadi, Shana Leopold, Martin J Zhang, Varsha Rao, Monika Avina, Tejaswini Mishra, Jethro Johnson, Brittany Lee-McMullen, Songjie Chen, Ahmed A Metwally, Thi Dong Binh Tran, Hoan Nguyen, Xin Zhou, Brandon Albright, Bo-Young Hong, Lauren M Petersen, Eddy J Bautista, Blake M Hanson, Lei Chen, Daniel Spakowicz, Amir Bahmani, Denis Salins, Benjamin Leopold, Melanie Ashland, Orit Dagan-Rosenfeld, Shannon Rego, Patricia Limcaoco, Elizabeth Colbert, Candice Allister, Dalia Perelman, Colleen Craig, Eric Wei, Hassan Chaib, Daniel Hornburg, Jessilyn Dunn, Liang Liang, Sophia Miryam Schüssler-Fiorenza Rose, Kim Kukurba, Brian Piening, Hannes Rost, David Tse, Tracey McLaughlin, Erica Sodergren, George M. Weinstock, and Michael Snyder
Longitudinal profiling of human blood transcriptome in healthy and lupus pregnancy., Seunghee Hong, Romain Banchereau, Bat-Sheva L Maslow, Marta M Guerra, Jacob Cardenas, Jeanine Baisch, D Ware Branch, T Flint Porter, Allen Sawitzke, Carl A Laskin, Jill P Buyon, Joan Merrill, Lisa R Sammaritano, Michelle Petri, Elizabeth Gatewood, Alma-Martina Cepika, Marina Ohouo, Gerlinde Obermoser, Esperanza Anguiano, Tae Whan Kim, John Nulsen, Djamel Nehar-Belaid, Derek Blankenship, Jacob Turner, Jacques Banchereau, Jane E Salmon, and Virginia Pascual
Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance., Jessica A Bertolini, Rebecca Favaro, Yanfen Zhu, Miriam Pagin, Chew Yee Ngan, Chee-Hong Wong, Harianto Tjong, Marit W Vermunt, Ben Martynoga, Cristiana Barone, Jessica Mariani, Marcos Julián Cardozo, Noemi Tabanera, Federico Zambelli, Sara Mercurio, Sergio Ottolenghi, Paul Robson, Menno P Creyghton, Paola Bovolenta, Giulio Pavesi, Francois Guillemot, Silvia K Nicolis, and Chia-Lin Wei
Meeting report: 32nd international mammalian genome conference., Jacob Moskowitz, Lauren Tracey, Samuel Widmayer, and Beth L Dumont
Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma., Rebecca A Buchanan, Kate E Foley, Keating W. Pepper, Alaina M Reagan, Kelly J Keezer, Amanda A Hewes, Cory A Diemler, Christoph Preuss, Ileana Soto, Simon W M John, and Gareth R Howell
Mesenchymal stem cells: From regeneration to cancer., Peishan Li, Zheng Gong, Leonard D. Shultz, and Guangwen Ren
Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease., Julia C Wilmanns, Raghav Pandey, Olivia Hon, Anjana Chandran, Jan M Schilling, Elvira Forte, Qizhu Wu, Gael Cagnone, Preeti Bais, Vivek M. Philip, David Coleman, Heidi Kocalis, Stuart K Archer, James T Pearson, Mirana Ramialison, Joerg Heineke, Hemal H Patel, Nadia Rosenthal, Milena B Furtado, and Mauro W Costa
MIA-Sig: multiplex chromatin interaction analysis by signal processing and statistical algorithms., Minji Kim, Meizhen Zheng, Simon Zhongyuan Tian, Byoungkoo Lee, Jeffrey Chuang, and Yijun Ruan
Microbiome Signatures Associated With Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease., Jeffrey B Schwimmer, Jethro S Johnson, Jorge E Angeles, Cynthia Behling, Patricia H Belt, Ingrid Borecki, Craig Bross, Janis Durelle, Nidhi P Goyal, Gavin Hamilton, Mary L Holtz, Joel E Lavine, Makedonka Mitreva, Kimberly P Newton, Amy Pan, Pippa M Simpson, Claude B Sirlin, Erica Sodergren, Rahul Tyagi, Katherine P Yates, George M. Weinstock, and Nita H Salzman
miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma., Wen Cai Zhang, Julie Wells, Kin-Hoe Chow, He Huang, Min Yuan, Tanvi Saxena, Mary Ann Melnick, Katerina Politi, John M Asara, Daniel B Costa, Carol J Bult, and Frank J Slack
miR-181a/b downregulation exerts a protective action on mitochondrial disease models., Alessia Indrieri, Sabrina Carrella, Alessia Romano, Alessandra Spaziano, Elena Marrocco, Erika Fernandez-Vizarra, Sara Barbato, Mariateresa Pizzo, Yulia Ezhova, Francesca M Golia, Ludovica Ciampi, Roberta Tammaro, Jorge Henao-Mejia, Adam Williams, Richard A Flavell, Elvira De Leonibus, Massimo Zeviani, Enrico M Surace, Sandro Banfi, and Brunella Franco
Mitotic chromosome alignment ensures mitotic fidelity by promoting interchromosomal compaction during anaphase., Cindy L Fonseca, Heidi L H Malaby, Leslie A Sepaniac, Whitney Martin, Candice Byers, Anne M Czechanski, Dana Messinger, Mary Tang, Ryoma Ohi, Laura G Reinholdt, and Jason Stumpff
Model validity for preclinical studies in precision medicine: precisely how precise do we need to be?, Abigail L.D. Tadenev and Robert W. Burgess
Mouse Genome Database (MGD) 2019., Carol J Bult, Judith A. Blake, Cynthia Smith, James A. Kadin, Joel E Richardson, and Mouse Genome Database Group
Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone mass., Larry D Mesner, Gina M Calabrese, Basel Al-Barghouthi, Daniel M. Gatti, John P Sundberg, Gary A Churchill, Dana A Godfrey, Cheryl L Ackert-Bicknell, and Charles R Farber
MSC: a metagenomic sequence classification algorithm., Subrata Saha, Jethro Johnson, Soumitra Pal, George M. Weinstock, and Sanguthevar Rajasekaran
Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function., Nathan Lawlor, Eladio J Marquez, Peter Orchard, Narisu Narisu, Muhammad Saad Shamim, Asa Thibodeau, Arushi Varshney, Romy Kursawe, Michael R Erdos, Matt Kanke, Huiya Gu, Evgenia Pak, Amalia Dutra, Sheikh Russell, Xingwang Li, Emaly Piecuch, Oscar Junhong Luo, Peter S Chines, Christian Fuchbserger, NIH Intramural Sequencing Center, Praveen Sethupathy, Aviva Presser Aiden, Yijun Ruan, Erez Lieberman Aiden, Francis S Collins, Duygu Ucar, Stephen C J Parker, and Michael L. Stitzel
Multi-platform discovery of haplotype-resolved structural variation in human genomes., Mark J P Chaisson, Ashley D Sanders, Xuefang Zhao, Ankit Malhotra, David Porubsky, Tobias Rausch, Eugene J Gardner, Oscar L Rodriguez, Li Guo, Ryan L Collins, Xian Fan, Jia Wen, Robert E Handsaker, Susan Fairley, Zev N Kronenberg, Xiangmeng Kong, Fereydoun Hormozdiari, Dillon Lee, Aaron M Wenger, Alex R Hastie, Danny Antaki, Thomas Anantharaman, Peter A Audano, Harrison Brand, Stuart Cantsilieris, Han Cao, Eliza Cerveira, Chong Chen, Xintong Chen, Chen-Shan Chin, Zechen Chong, Nelson T Chuang, Christine C Lambert, Deanna M Church, Laura Clarke, Andrew Farrell, Joey Flores, Timur Galeev, David U Gorkin, Madhusudan Gujral, Victor Guryev, William Haynes Heaton, Jonas Korlach, Sushant Kumar, Jee Young Kwon, Ernest T Lam, Jong Eun Lee, Joyce Lee, Wan-Ping Lee, Sau Peng Lee, Shantao Li, Patrick Marks, Karine Viaud-Martinez, Sascha Meiers, Katherine M Munson, Fabio C P Navarro, Bradley J Nelson, Conor Nodzak, Amina Noor, Sofia Kyriazopoulou-Panagiotopoulou, Andy W C Pang, Yunjiang Qiu, Gabriel Rosanio, Mallory Ryan, Adrian Stütz, Diana C J Spierings, Alistair Ward, AnneMarie E Welch, Ming Xiao, Wei Xu, Chengsheng Zhang, Qihui Zhu, Xiangqun Zheng-Bradley, Ernesto Lowy, Sergei Yakneen, Steven McCarroll, Goo Jun, Li Ding, Chong Lek Koh, Bing Ren, Paul Flicek, Ken Chen, Mark B Gerstein, Pui-Yan Kwok, Peter M Lansdorp, Gabor T Marth, Jonathan Sebat, Xinghua Shi, Ali Bashir, Kai Ye, Scott E Devine, Michael E Talkowski, Ryan E Mills, Tobias Marschall, Jan O Korbel, Evan E Eichler, and Charles Lee
Multiplex chromatin interactions with single-molecule precision., Meizhen Zheng, Simon Zhongyuan Tian, Daniel Capurso, Minji Kim, Rahul Maurya, Byoungkoo Lee, Emaly Piecuch, Liang Gong, Jacqueline Jufen Zhu, Zhihui Li, Chee-Hong Wong, Chew Yee Ngan, Ping Wang, Xiaoan Ruan, Chia-Lin Wei, and Yijun Ruan
Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells., Eleni P Mimitou, Anthony Cheng, Antonino Montalbano, Stephanie Hao, Marlon Stoeckius, Mateusz Legut, Timothy Roush, Alberto Herrera, Efthymia Papalexi, Zhengqing Ouyang, Rahul Satija, Neville E Sanjana, Sergei B Koralov, and Peter Smibert
Mutations in DNA repair genes are associated with increased neoantigen burden and a distinct immunophenotype in lung squamous cell carcinoma., Young Kwang Chae, Jonathan F Anker, Michael S Oh, Preeti Bais, Sandeep Namburi, Sarita Agte, Francis J Giles, and Jeffrey H Chuang
Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle., Qingnian Goh, Taejeong Song, Michael J Petrany, Alyssa Aw Cramer, Chengyi Sun, Sakthivel Sadayappan, Se-Jin Lee, and Douglas P Millay
Nail abnormalities identified in an ageing study of 30 inbred mouse strains., Sarah C Linn, Allison M Mustonen, Kathleen A Silva, Victoria E. Kennedy, Beth A. Sundberg, Lesley S Bechtold, Sarah Alghamdi, Robert Hoehndorf, Paul N Schofield, and John P Sundberg
Network-Based Functional Prediction Augments Genetic Association To Predict Candidate Genes for Histamine Hypersensitivity in Mice., Anna L. Tyler, Abbas Raza, Dimitry N Krementsov, Laure K Case, Rui Huang, Runlin Z Ma, Elizabeth P Blankenhorn, Cory Teuscher, and J Matthew Mahoney
New insights into regulation and function of planar polarity in the inner ear., Basile Tarchini and Xiaowei Lu
N-terminal alternative splicing of GluN1 regulates the maturation of excitatory synapses and seizure susceptibility., Hong Liu, Haoyi Wang, Matthew Peterson, Wen Zhang, Guoqiang Hou, and Zhong-Wei Zhang
One reference genome is not enough., Xiaofei Yang, Wan-Ping Lee, Kai Ye, and Charles Lee
On Finding and Enumerating Maximal and Maximum k-Partite Cliques in k-Partite Graphs, Charles A. Phillips, Kai Wang, Erich J. Baker, Jason A. Bubier, Elissa J Chesler, and Michael A. Langston
Opinion: Greater diversity is needed in human genomic data., Charles Lee
Opportunities, resources, and techniques for implementing genomics in clinical care., Teri A Manolio, Robb Rowley, Marc S Williams, Dan Roden, Geoffrey S Ginsburg, Carol J Bult, Rex L Chisholm, Patricia A Deverka, Howard L McLeod, George A Mensah, Mary V Relling, Laura Lyman Rodriguez, Cecelia Tamburro, and Eric D Green
Oral Microbiome in HIV-Infected Women: Shifts in the Abundance of Pathogenic and Beneficial Bacteria Are Associated with Aging, HIV Load, CD4 Count, and Antiretroviral Therapy., Tyler Lewy, Bo-Young Hong, Barbara Weiser, Harold Burger, Andrew Tremain, George M. Weinstock, Kathryn Anastos, and Michael D George
Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target., Jun Wei, Anantha Marisetty, Brett Schrand, Konrad Gabrusiewicz, Yuuri Hashimoto, Martina Ott, Zacharia Grami, Ling-Yuan Kong, Xiaoyang Ling, Hillary Caruso, Shouhao Zhou, Y Alan Wang, Gregory N Fuller, Jason Huse, Eli Gilboa, Nannan Kang, Xingxu Huang, Roel G W Verhaak, Shulin Li, and Amy B Heimberger
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors., Alessandro Carugo, Rosalba Minelli, Luigi Sapio, Melinda Soeung, Federica Carbone, Frederick S Robinson, James Tepper, Ziheng Chen, Sara Lovisa, Maria Svelto, Samirkumar B Amin, Sanjana Srinivasan, Edoardo Del Poggetto, Sara Loponte, Francesca Puca, Prasenjit Dey, Gabriel G Malouf, Xiaoping Su, Liren Li, Dolores Lopez-Terrada, Dinesh Rakheja, Alexander J Lazar, George J Netto, Priya Rao, Alessandro Sgambato, Anirban Maitra, Durga N Tripathi, Cheryl L Walker, Jose A Karam, Timothy P Heffernan, Andrea Viale, Charles W M Roberts, Pavlos Msaouel, Nizar M Tannir, Giulio F Draetta, and Giannicola Genovese
PDX Finder: A portal for patient-derived tumor xenograft model discovery., Nathalie Conte, Jeremy C Mason, Csaba Halmagyi, Steven Neuhauser, Abayomi Mosaku, Galabina Yordanova, Aikaterini Chatzipli, Dale A. Begley, Debra M Krupke, Helen Parkinson, Terrence F Meehan, and Carol J Bult
PEDIA: prioritization of exome data by image analysis., Tzung-Chien Hsieh, Martin A Mensah, Jean T Pantel, Dione Aguilar, Omri Bar, Allan Bayat, Luis Becerra-Solano, Heidi B Bentzen, Saskia Biskup, Oleg Borisov, Oivind Braaten, Claudia Ciaccio, Marie Coutelier, Kirsten Cremer, Magdalena Danyel, Svenja Daschkey, Hilda David Eden, Koenraad Devriendt, Sandra Wilson, Sofia Douzgou, Dejan Đukić, Nadja Ehmke, Christine Fauth, Björn Fischer-Zirnsak, Nicole Fleischer, Heinz Gabriel, Luitgard Graul-Neumann, Karen W Gripp, Yaron Gurovich, Asya Gusina, Nechama Haddad, Nurulhuda Hajjir, Yair Hanani, Jakob Hertzberg, Konstanze Hoertnagel, Janelle Howell, Ivan Ivanovski, Angela Kaindl, Tom Kamphans, Susanne Kamphausen, Catherine Karimov, Hadil Kathom, Anna Keryan, Alexej Knaus, Sebastian Köhler, Uwe Kornak, Alexander Lavrov, Maximilian Leitheiser, Gholson J Lyon, Elisabeth Mangold, Purificación Marín Reina, Antonio Martinez Carrascal, Diana Mitter, Laura Morlan Herrador, Guy Nadav, Markus Nöthen, Alfredo Orrico, Claus-Eric Ott, Kristen Park, Borut Peterlin, Laura Pölsler, Annick Raas-Rothschild, Linda Randolph, Nicole Revencu, Christina Ringmann Fagerberg, Peter N Robinson, Stanislav Rosnev, Sabine Rudnik, Gorazd Rudolf, Ulrich Schatz, Anna Schossig, Max Schubach, Or Shanoon, Eamonn Sheridan, Pola Smirin-Yosef, Malte Spielmann, Eun-Kyung Suk, Yves Sznajer, Christian T Thiel, Gundula Thiel, Alain Verloes, Irena Vrecar, Dagmar Wahl, Ingrid Weber, Korina Winter, Marzena Wiśniewska, Bernd Wollnik, Ming W Yeung, Max Zhao, Na Zhu, Johannes Zschocke, Stefan Mundlos, Denise Horn, and Peter M Krawitz
Perceived Gaps in Genetics Training Among Audiologists and Speech-Language Pathologists: Lessons From a National Survey., Beate Peter, Michael J Dougherty, E Kate Reed, Emily A Edelman, and Karen Hanson
PlantSimLab - a modeling and simulation web tool for plant biologists., S Ha, E Dimitrova, S Hoops, D Altarawy, M Ansariola, D Deb, J Glazebrook, R Hillmer, H Shahin, F Katagiri, J McDowell, M Megraw, J Setubal, B M Tyler, and Reinhard Laubenbacher
PRAS: Predicting functional targets of RNA binding proteins based on CLIP-seq peaks., Jianan Lin, Yuping Zhang, Wayne N Frankel, and Zhengqing Ouyang
Prdm9 and Meiotic Cohesin Proteins Cooperatively Promote DNA Double-Strand Break Formation in Mammalian Spermatocytes., Tanmoy Bhattacharyya, Michael Walker, Natalie Powers, Catherine Brunton, Alexander D Fine, Petko M. Petkov, and Mary Ann Handel
Preclinical rationale for entinostat in embryonal rhabdomyosarcoma., Narendra Bharathy, Noah E Berlow, Eric Wang, Jinu Abraham, Teagan P Settelmeyer, Jody E Hooper, Matthew N Svalina, Zia Bajwa, Martin W Goros, Brian S Hernandez, Johannes E Wolff, Ranadip Pal, Angela M Davies, Arya Ashok, Darnell Bushby, Maria Mancini, Christopher Noakes, Neal C Goodwin, Peter Ordentlich, James G. Keck, Douglas S Hawkins, Erin R Rudzinski, Atiya Mansoor, Theodore J Perkins, Christopher R Vakoc, Joel E Michalek, and Charles Keller
Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma., Noah E Berlow, Rishi Rikhi, Mathew Geltzeiler, Jinu Abraham, Matthew N Svalina, Lara E Davis, Erin Wise, Maria Mancini, Jonathan Noujaim, Atiya Mansoor, Michael J Quist, Kevin L Matlock, Martin W Goros, Brian S Hernandez, Yee C Doung, Khin Thway, Tomohide Tsukahara, Jun Nishio, Elaine T Huang, Susan Airhart, Carol J Bult, Regina Gandour-Edwards, Robert G Maki, Robin L Jones, Joel E Michalek, Milan Milovancev, Souparno Ghosh, Ranadip Pal, and Charles Keller
Proliferative Typhlocolitis With Multinucleated Giant Cells: A Nonspecific Enteropathy in Immunodeficient Sentinel Mice., Kerriann M Casey, Amanda L Johnson, Melea N Hunrath, Jenelle K Fraser, Nicole C McCowan, Katherine Wasson, Rosalinda A. Doty, Stephen M Griffey, and Denise M Imai
Provider engagement in precision oncology education: an exploratory analysis of online continuing medical education data., Emily A Edelman, Paige C Tanner, Katherine Aj Taber, Sean C McConnell, Laura J Nicholson, Therese Ingram, Linda Steinmark, and Eleanor K Reed
Quantitative evaluation of ontology design patterns for combining pathology and anatomy ontologies., Sarah M Alghamdi, Beth A. Sundberg, John P Sundberg, Paul N Schofield, and Robert Hoehndorf
Quantitative Trait Locus and Integrative Genomics Revealed Candidate Modifier Genes for Ectopic Mineralization in Mouse Models of Pseudoxanthoma Elasticum., Qiaoli Li, Vivek M. Philip, Timothy M Stearns, Jason A. Bubier, Benjamin L King, Benjamin E. Low, Michael V. Wiles, Amir Hossein Saeidian, Beth A. Sundberg, Jouni Uitto, and John P Sundberg
Rapid growth is a dominant predictor of hepcidin suppression and declining ferritin in Gambian infants., Andrew E Armitage, Schadrac C Agbla, Modupeh Betts, Ebrima A Sise, Momodou W Jallow, Ellen Sambou, Bakary Darboe, Archibald Worwui, George M. Weinstock, Martin Antonio, Sant-Rayn Pasricha, Andrew M Prentice, Hal Drakesmith, Momodou K Darboe, and Brenda Anna Kwambana-Adams
Recoding the metagenome: microbiome engineering in situ., Travis Whitfill and Julia Oh
Recommended housing densities for research mice: filling the gap in data-driven alternatives., Karen L. Svenson and Beverly J Paigen
Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation., Danielle A Simmons, Frederick M Lartey, Emil Schüler, Marjan Rafat, Gregory King, Anna Kim, Ryan Ko, Sarah Semaan, Selena Gonzalez, Melissa Jenkins, Pooja Pradhan, Zion Shih, Jinghui Wang, Rie von Eyben, Edward E Graves, Peter G Maxim, Frank M Longo, and Billy W Loo
Reference Trait Analysis Reveals Correlations Between Gene Expression and Quantitative Traits in Disjoint Samples., Daniel A Skelly, Narayanan Raghupathy, Ray F. Robledo, Joel H. Graber, and Elissa J Chesler
Regulation of intrinsic excitability: Roles for learning and memory, aging and Alzheimer's disease, and genetic diversity., Amy R Dunn and Catherine Kaczorowski
Representing glycophenotypes: semantic unification of glycobiology resources for disease discovery., Jean-Philippe F Gourdine, Matthew H Brush, Nicole A Vasilevsky, Kent Shefchek, Sebastian Köhler, Nicolas Matentzoglu, Monica C Munoz-Torres, Julie A McMurry, Xingmin Aaron Zhang, Peter N Robinson, and Melissa A Haendel
Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model., Yueqin Zhou, Sharon Carmona, A K M G Muhammad, Shaughn Bell, Jesse Landeros, Michael Vazquez, Ritchie Ho, Antonietta Franco, Bin Lu, Gerald W Dorn, Shaomei Wang, Cathleen Lutz, and Robert H Baloh
Robust mouse tracking in complex environments using neural networks., Brian Q Geuther, Sean P Deats, Kai J Fox, Stephen A Murray, Robert E Braun, Jacqueline K White, Elissa J Chesler, Cathleen Lutz, and Vivek Kumar
R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations., Karl W Broman, Daniel M Gatti, Petr Simecek, Nicholas A Furlotte, Pjotr Prins, Śaunak Sen, Brian S Yandell, and Gary Churchill
Sarcomere-Directed Calcium Reporters in Cardiomyocytes., Stuart G Campbell, Yibing Qyang, and J Travis Hinson
Selective colonization ability of human fecal microbes in different mouse gut environments., Wei Zhou, Kin-Hoe Chow, Elizabeth Fleming, and Julia Oh
Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery., Xingmin Aaron Zhang, Amy Yates, Nicole Vasilevsky, J P Gourdine, Tiffany J Callahan, Leigh Carmody, Daniel Danis, Marcin P Joachimiak, Vida Ravanmehr, Emily R Pfaff, James Champion, Kimberly Robasky, Hao Xu, Karamarie Fecho, Nephi A Walton, Richard L Zhu, Justin Ramsdill, Christopher J Mungall, Sebastian Köhler, Melissa A Haendel, Clement J McDonald, Daniel J Vreeman, David B Peden, Tellen D Bennett, James A Feinstein, Blake Martin, Adrianne L Stefanski, Lawrence E Hunter, Christopher G Chute, and Peter N Robinson
Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis., Matthew A Loberg, Rebecca K Bell, Leslie Goodwin, Elizabeth Eudy, Linde A Miles, Jennifer M SanMiguel, Kira Young, David E. Bergstrom, Ross L Levine, Rebekka K Schneider, and Jennifer J. Trowbridge
Seroconversion of 1-year-old Mice to Murine Norovirus., Julia Zaias, Catia Farrington, Robert S Livingston, and Linda Waterman
Significant Strain Variation in the Mutation Spectra of Inbred Laboratory Mice., Beth L Dumont
Single-cell transcriptomic analysis of the lateral hypothalamic area reveals molecularly distinct populations of inhibitory and excitatory neurons., Laura E Mickelsen, Mohan Bolisetty, Brock R Chimileski, Akie Fujita, Eric J Beltrami, James T Costanzo, Jacob R Naparstek, Paul Robson, and Alexander C Jackson
Single cell transcriptomics based-MacSpectrum reveals novel macrophage activation signatures in diseases., Chuan Li, Antoine Menoret, Cullen Farragher, Zhengqing Ouyang, Christopher Bonin, Paul Holvoet, Anthony T Vella, and Beiyan Zhou
Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct mRNA Isoforms in Human Bone Marrow Cell Subpopulations., Anne DeslattesMays, Marcel Schmidt, Garrett Graham, Elizabeth Tseng, Primo Baybayan, Robert Sebra, Miloslav Sanda, Jean-Baptiste Mazarati, Anna Riegel, and Anton Wellstein
Somatic Testing: Implications for Targeted Treatment., E Kate Reed, Linda Steinmark, Diane C Seibert, and Emily A Edelman
Sox2-Dependent 3D Chromatin Interactomes in Transcription, Neural Stem Cell Proliferation and Neurodevelopmental Diseases., Chia-Lin Wei, Silvia K Nicolis, Yanfen Zhu, and Miriam Pagin
Spatial chromatin architecture alteration by structural variations in human genomes at the population scale., Michal Sadowski, Agnieszka Kraft, Przemyslaw Szalaj, Michal Wlasnowolski, Zhonghui Tang, Yijun Ruan, and Dariusz Plewczynski
Split selectable markers., Nathaniel L. Jillette, Menghan Du, Jacqueline Jufen Zhu, Peter Cardoz, and Albert W Cheng
Spontaneous mutations of the Zpld1 gene in mice cause semicircular canal dysfunction but do not impair gravity receptor or hearing functions., Sarath Vijayakumar, Sherri M Jones, Timothy A Jones, Cong Tian, and Kenneth R. Johnson
Structure and function of the immune system in the spleen., Steven M Lewis, Adam Williams, and Stephanie C Eisenbarth
Symbiotic organs shaped by distinct modes of genome evolution in cephalopods., Mahdi Belcaid, Giorgio Casaburi, Sarah J McAnulty, Hannah Schmidbaur, Andrea M Suria, Silvia Moriano-Gutierrez, M Sabrina Pankey, Todd H Oakley, Natacha Kremer, Eric J Koch, Andrew J Collins, Hoan Nguyen, Sai H Lek, Irina Goncharenko-Foster, Patrick Minx, Erica Sodergren Weinstock, George M. Weinstock, Daniel S Rokhsar, Margaret McFall-Ngai, Oleg Simakov, Jamie S Foster, and Spencer V Nyholm
Systems genetics of sensation seeking., Price E. Dickson, Tyler A Roy, Kathryn A. McNaughton, Troy Wilcox, Padam Kumar, and Elissa J Chesler
TBX1 is required for normal stria vascularis and semicircular canal development., Cong Tian and Kenneth R. Johnson
Technical and Regulatory Considerations for Taking Liquid Biopsy to the Clinic: Validation of the JAX PlasmaMonitor, Bridgette Sisson, Jasmina Uvalic, Kevin Kelly, Pavalan Selvam, Andrew N Hesse, Guruprasad Ananda, Harshpreet Chandok, Daniel Bergeron, Lauren Holinka, and Honey V Reddi
Testing Pleiotropy vs. Separate QTL in Multiparental Populations., Frederick J Boehm, Elissa J Chesler, Brian S Yandell, and Karl W Broman
Testing the gene expression classification of the EMT spectrum., Dongya Jia, Jason T George, Satyendra C Tripathi, Deepali L Kundnani, Mingyang Lu, Samir M Hanash, José N Onuchic, Mohit Kumar Jolly, and Herbert Levine
TeXP: Deconvolving the effects of pervasive and autonomous transcription of transposable elements., Fabio Cp Navarro, Jacob Hoops, Lauren Bellfy, Eliza Cerveira, Qihui Zhu, Chengsheng Zhang, Charles Lee, and Mark B Gerstein
Thanatomicrobiome composition profiling as a tool for forensic investigation., Wei Zhou and Yingnan Bian
The 5th International 3D Genomics Workshop 2018: conference report., Yan Zhang, Yijun Ruan, and Guoliang Li
The Alliance of Genome Resources: Building a Modern Data Ecosystem for Model Organism Databases., Alliance of Genome Resources Consortium, Carol J Bult, Judith A. Blake, Brian R Calvi, J. Michael Cherry, Valentina DiFrancesco, Robert Fullem, Kevin L Howe, Thom Kaufman, Chris Mungall, Norbert Perrimon, Mary Shimoyama, Paul W Sternberg, Paul Thomas, and Monte Westerfield
The contribution of microRNA-mediated regulation to short- and long-term gene expression predictability., Russell Posner and Reinhard Laubenbacher
The effects of MicroRNA deregulation on pre-RNA processing network in multiple myeloma., Sophia Adamia, Ivane Abiatari, Samir Amin, Mariateresa Fulciniti, Stephane Minvielle, Cheng Li, Philippe Moreau, Herve Avet-Loiseau, Nikhil C Munshi, and Kenneth C Anderson
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis., Jordan P Lewandowski, James C Lee, Taeyoung Hwang, Hongjae Sunwoo, Jill M Goldstein, Abigail F Groff, Nydia P Chang, William Mallard, Adam Williams, Jorge Henao-Meija, Richard A Flavell, Jeannie T Lee, Chiara Gerhardinger, Amy J Wagers, and John L Rinn
The Gene Ontology Resource: 20 years and still GOing strong., Gene Ontology Consortium
The Genetics of Neuropathic Pain from Model Organisms to Clinical Application., Margarita Calvo, Alexander J Davies, Harry L Hébert, Greg A Weir, Elissa J Chesler, Nanna B Finnerup, Roy C Levitt, Blair H Smith, G Gregory Neely, Michael Costigan, and David L Bennett
The Genome of C57BL/6J "Eve", the Mother of the Laboratory Mouse Genome Reference Strain., Vishal Kumar Sarsani, Narayanan Raghupathy, Ian T Fiddes, Joel Armstrong, Francoise Thibaud-Nissen, Oraya Zinder, Mohan Bolisetty, Kerstin Howe, Doug Hinerfeld, Xiaoan Ruan, Lucy B. Rowe, Mary Barter, Guruprasad Ananda, Benedict Paten, George M. Weinstock, Gary Churchill, Michael V. Wiles, Valerie A Schneider, Anuj Srivastava, and Laura G Reinholdt
The Global State of the Genetic Counseling Profession., MaryAnn Abacan, Lamia Alsubaie, Kristine Barlow-Stewart, Beppy Caanen, Christophe Cordier, Eliza Courtney, Emeline Davoine, Janice Edwards, Niby J Elackatt, Kate Gardiner, Yue Guan, Lian-Hua Huang, Charlotta Ingvoldstad Malmgren, Sahil Kejriwal, Hyon J Kim, Deborah Lambert, Paulina Araceli Lantigua-Cruz, Juliana M H Lee, Marianne Lodahl, Åshild Lunde, Shelley Macaulay, Ivan Macciocca, Sonia Margarit, Anna Middleton, Ramona Moldovan, Joanne Ngeow, Alexandra J Obregon-Tito, Kelly E Ormond, Milena Paneque, Karen Powell, Kunal Sanghavi, Diana Scotcher, Jenna Scott, Clara Serra Juhé, Shiri Shkedi-Rafid, Tina-Marié Wessels, Sook-Yee Yoon, and Catherine Wicklund
The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions., Zoltan Nagy, Timo Vögtle, Mitchell J Geer, Jun Mori, Silke Heising, Giada Di Nunzio, Ralph Gareus, Alexander Tarakhovsky, Arthur Weiss, Benjamin G Neel, Guillaume E Desanti, Alexandra Mazharian, and Yotis A Senis
The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs., Anthony T Virtue, Sam J McCright, Jasmine M Wright, Monica T Jimenez, Walter K Mowel, Jonathan J Kotzin, Leonel Joannas, Megha G Basavappa, Sean P Spencer, Megan L Clark, Stephen H Eisennagel, Adam Williams, Maayan Levy, Sasikanth Manne, Sarah E Henrickson, E John Wherry, Christoph A Thaiss, Eran Elinav, and Jorge Henao-Mejia
The Jackson Laboratory Annual Report 1991, Office of Public Information
The JAX Synteny Browser for mouse-human comparative genomics., Georgi Kolishovski, Anna Lamoureux, Paul Hale, Joel E Richardson, Jill M. Recla, Omoluyi Adesanya, Allen K. Simons, Govindarajan Kunde-Ramamoorthy, and Carol J Bult
The long noncoding RNA Morrbid regulates CD8 T cells in response to viral infection., Jonathan J Kotzin, Fany Iseka, Jasmine Wright, Megha G Basavappa, Megan L Clark, Mohammed-Alkhatim Ali, Mohamed S Abdel-Hakeem, Tanner F Robertson, Walter K Mowel, Leonel Joannas, Vanessa D Neal, Sean P Spencer, Camille M Syrett, Montserrat C Anguera, Adam Williams, E John Wherry, and Jorge Henao-Mejia
The lung microbiome, vitamin D, and the tuberculous granuloma: A balance triangle., María Elvira Balcells, Noemí Yokobori, Bo-Young Hong, John Corbett, and Jorge Cervantes
The mouse Gene Expression Database (GXD): 2019 update., Constance M. Smith, Terry F. Hayamizu, Jacqueline H. Finger, Susan M. Bello, Ingeborg J. McCright, Jingxia Xu, Richard M. Baldarelli, Jonathan S Beal, Jeffrey Campbell, Lori E. Corbani, Pete J. Frost, Jill R Lewis, Sharon C Giannatto, Dave Miers, David R. Shaw, James A. Kadin, Joel E Richardson, Cynthia Smith, and Martin Ringwald
Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction., Anne S De Groot, Gail Skowron, James Robert White, Christine Boyle, Guilhem Richard, David V. Serreze, and William D Martin
The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming., Victor A Ruthig, Matthew B Friedersdorf, Jason A Garness, Steven C. Munger, Corey Bunce, Jack D Keene, and Blanche Capel
The Role of Emotional Contagion in the Distress Exhibited by Grouped Mice Exposed to CO₂., Andrea D Moffitt, Laurie L Brignolo, Amir Ardeshir, and Michelle A Creamer-Hente
The Roles of Cholesterol and Its Metabolites in Normal and Malignant Hematopoiesis., Hideyuki Oguro
The Synaptic Vesicle Glycoprotein 2: Structure, Function, and Disease Relevance., Kristen A Stout, Amy R Dunn, Carlie Hoffman, and Gary W Miller
The upper-airway microbiota and loss of asthma control among asthmatic children., Yanjiao Zhou, Daniel Jackson, Leonard B Bacharier, David Mauger, Homer Boushey, Mario Castro, Juliana Durack, Yvonne Huang, Robert F Lemanske, Gregory A Storch, George M. Weinstock, Kristine Wylie, Ronina Covar, Anne M Fitzpatrick, Wanda Phipatanakul, Rachel G Robison, and Avraham Beigelman
Three things every nurse practitioner can do to integrate genetics into practice., E Kate Reed, Therese Ingram, and Emily A Edelman
Tissue-Specific Trans Regulation of the Mouse Epigenome., Christopher L. Baker, Michael Walker, Seda Arat, Guruprasad Ananda, Pavlina Petkova, Natalie Powers, Hui Tian, Catrina Spruce, Bo Ji, Dylan Rausch, Kwangbom Choi, Petko M. Petkov, Gregory W. Carter, and Kenneth Paigen
Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop., Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Chowell, Lisa M Coussens, Daniel D De Carvalho, David G DeNardo, Jérôme Galon, Howard L Kaufman, Tomas Kirchhoff, Michael T Lotze, Jason J Luke, Andy J Minn, Katerina Politi, Leonard D. Shultz, Richard Simon, Vésteinn Thórsson, Joanne B Weidhaas, Maria Libera Ascierto, Paolo Antonio Ascierto, James M Barnes, Valentin Barsan, Praveen K Bommareddy, Adrian Bot, Sarah E Church, Gennaro Ciliberto, Andrea De Maria, Dobrin Draganov, Winson S Ho, Heather M McGee, Anne Monette, Joseph F Murphy, Paola Nisticò, Wungki Park, Maulik Patel, Michael Quigley, Laszlo Radvanyi, Harry Raftopoulos, Nils-Petter Rudqvist, Alexandra Snyder, Randy F Sweis, Sara Valpione, Lisa H Butterfield, Mary L Disis, Bernard A Fox, Alessandra Cesano, and Francesco M Marincola
Toward Regeneration of the Heart: Bioengineering Strategies for Immunomodulation., Arianna Ferrini, Molly M Stevens, Susanne Sattler, and Nadia Rosenthal
Towards large scale automated cage monitoring - Diurnal rhythm and impact of interventions on in-cage activity of C57BL/6J mice recorded 24/7 with a non-disrupting capacitive-based technique., Karin Pernold, F Iannello, Benjamin E. Low, M Rigamonti, G Rosati, F Scavizzi, J Wang, M Raspa, Michael V. Wiles, and B Ulfhake
Transcriptional profiling predicts running promotes cerebrovascular remodeling in young but not midlife mice., Kate E Foley, Hongtian Stanley Yang, Leah C. Graham, and Gareth R Howell
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases., Akul Singhania, Christine M Graham, Leona Gabryšová, Lúcia Moreira-Teixeira, Evangelos Stavropoulos, Jonathan M Pitt, Probir Chakravarty, Annika Warnatsch, William J Branchett, Laura Conejero, Jing-Wen Lin, Sophia Davidson, Mark S Wilson, Gregory Bancroft, Jean Langhorne, Eva Frickel, Abdul K Sesay, Simon L Priestnall, Eleanor Herbert, Marianna Ioannou, Qian Wang, Ian R Humphreys, Jonathan Dodd, Peter J M Openshaw, Katrin D Mayer-Barber, Dragana Jankovic, Alan Sher, Clare M Lloyd, Nicole Baldwin, Damien Chaussabel, Venizelos Papayannopoulos, Andreas Wack, Jacques Banchereau, Virginia M Pascual, and Anne O'Garra
Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity., Hongtian Yang, Leah C. Graham, Alaina M Reagan, Weronika Grabowska, William H. Schott, and Gareth R Howell
Tumor Origins Through Genomic Profiles., Edison Liu and Susan M Mockus
Ultra-long Read Sequencing for Whole Genomic DNA Analysis., Liang Gong, Chee-Hong Wong, Jennifer Idol, Chew Yee Ngan, and Chia-Lin Wei
Uncoupling of transcriptomic and cytological differentiation in mouse spermatocytes with impaired meiosis., Alexander D Fine, Robyn L Ball, Yasuhiro Fujiwara, Mary Ann Handel, and Gregory W. Carter
Unstable Genome and Transcriptome Dynamics during Tumor Metastasis Contribute to Therapeutic Heterogeneity in Colorectal Cancers., Sung-Yup Cho, Jeesoo Chae, Deukchae Na, Wonyoung Kang, Ahra Lee, Seoyeon Min, Jinjoo Kang, Boram Choi, Jieun Lee, Chang Ohk Sung, Jeffrey Chuang, Charles Lee, Won-Suk Lee, Hansoo Park, and Jong-Il Kim
Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom"., Georgia Charkoftaki, Yewei Wang, Monica McAndrews, Elspeth A Bruford, David C Thompson, Vasilis Vasiliou, and Daniel W Nebert
Urolithiasis Is a Risk Factor for Uroseptic Shock and Acute Kidney Injury in Patients With Urinary Tract Infection., Chih-Yen Hsiao, Tsung-Hsien Chen, Yi-Chien Lee, Meng-Chang Hsiao, Peir-Haur Hung, Yih-Yuan Chen, and Ming-Cheng Wang
Utility of the JAX Clinical Knowledgebase in capture and assessment of complex genomic cancer data., Sara E. Patterson, Cara M. Statz, Taofei Yin, and Susan Mockus
Variable outcomes of human heart attack recapitulated in genetically diverse mice., Ekaterina Salimova, Kristen J Nowak, Ana C Estrada, Milena B Furtado, Elyshia McNamara, Quang Nguyen, Lois Balmer, Christoph Preuss, Jeffrey W Holmes, Mirana Ramialison, Grant Morahan, and Nadia Rosenthal
Vascular Inflammation Risk Factors in Retinal Disease., Ileana Soto, Mark P. Krebs, Alaina M Reagan, and Gareth R Howell
Visual Discrimination, Serial Reversal, and Extinction Learning in the, Price E. Dickson and Guy Mittleman
What are the earlier life contributions to reserve and resilience?, Kristine B Walhovd, Gareth R Howell, Stuart J Ritchie, Roger T Staff, and Carl W Cotman