Content Posted in 2020
Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses., L J Blumberg, J E Humphries, S D Jones, L B Pearce, R Holgate, A Hearn, J Cheung, A Mahmood, B Del Tito, J S Graydon, L E Stolz, A Bitonti, S Purohit, D de Graaf, K Kacena, J T Andersen, Gregory J. Christianson, Derry C. Roopenian, J J Hubbard, A K Gandhi, K Lasseter, M Pyzik, and R S Blumberg
Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice., Charles B Wright, Hironori Uehara, Younghee Kim, Tetsuhiro Yasuma, Reo Yasuma, Shuichiro Hirahara, Ryan D Makin, Ivana Apicella, Felipe Pereira, Yosuke Nagasaka, Siddharth Narendran, Shinichi Fukuda, Romulo Albuquerque, Benjamin J Fowler, Ana Bastos-Carvalho, Philippe Georgel, Izuho Hatada, Bo Chang, Nagaraj Kerur, Balamurali K Ambati, Jayakrishna Ambati, and Bradley D Gelfand
Colon Cancer Prevention with Walnuts: A Longitudinal Study in Mice from the Perspective of a Gut Enterotype-like Cluster., Yanfei Chen, Masako Nakanishi, Eddy J Bautista, Veneta Qendro, Erica Sodergren, Daniel W Rosenberg, and George M. Weinstock
Discovery of a new predominant cytosine DNA modification that is linked to gene expression in malaria parasites., Elie Hammam, Guruprasad Ananda, Ameya Sinha, Christine Scheidig-Benatar, Mylene Bohec, Peter R Preiser, Peter C Dedon, Artur Scherf, and Shruthi S Vembar
From GWAS Association to Function: Candidate Gene Screening Within Insulin Resistance-Associated Genomic Loci Using a Preadipocyte Differentiation Model., Feria A Ladha, Michael L. Stitzel, and J Travis Hinson
Gene therapies for axonal neuropathies: Available strategies, successes to date, and what to target next., Kathryn H Morelli, Courtney L Hatton, Scott Q Harper, and Robert W. Burgess
Genetic Interactions Affect Lung Function in Patients with Systemic Sclerosis., Anna L. Tyler, J Matthew Mahoney, and Gregory W. Carter
Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer's disease., Ravi S Pandey, Leah C. Graham, Asli Uyar, Christoph Preuss, Gareth R Howell, and Gregory W. Carter
Human and mouse essentiality screens as a resource for disease gene discovery., Pilar Cacheiro, Violeta Muñoz-Fuentes, Stephen A. Murray, Mary E Dickinson, Maja Bucan, Lauryl M J Nutter, Kevin A Peterson, Hamed Haselimashhadi, Ann M Flenniken, Hugh Morgan, Henrik Westerberg, Tomasz Konopka, Chih-Wei Hsu, Audrey Christiansen, Denise G Lanza, Arthur L Beaudet, Jason D Heaney, Helmut Fuchs, Valerie Gailus-Durner, Tania Sorg, Jan Prochazka, Vendula Novosadova, Christopher J Lelliott, Hannah Wardle-Jones, Sara Wells, Lydia Teboul, Heather Cater, Michelle Stewart, Tertius Hough, Wolfgang Wurst, Radislav Sedlacek, David J Adams, John R Seavitt, Glauco Tocchini-Valentini, Fabio Mammano, Robert E Braun, Colin McKerlie, Yann Herault, Martin Hrabě de Angelis, Ann-Marie Mallon, K C Kent Lloyd, Steve D M Brown, Helen Parkinson, Terrence F Meehan, Damian Smedley, Genomics England Research Consortium, and International Mouse Phenotyping Consortium
Loss of ADAMTS19 causes progressive non-syndromic heart valve disease., Florian Wünnemann, Asaf Ta-Shma, Christoph Preuss, Severine Leclerc, Patrick Piet van Vliet, Andrea Oneglia, Maryse Thibeault, Emily Nordquist, Joy Lincoln, Franka Scharfenberg, Christoph Becker-Pauly, Philipp Hofmann, Kirstin Hoff, Enrique Audain, Hans-Heiner Kramer, Wojciech Makalowski, Amiram Nir, Sebastian S Gerety, Matthew Hurles, Johanna Comes, Anne Fournier, Hanna Osinska, Jeffrey Robins, Michel Pucéat, Orly Elpeleg, Marc-Phillip Hitz, and Gregor Andelfinger
Ly6a Differential Expression in Blood-Brain Barrier Is Responsible for Strain Specific Central Nervous System Transduction Profile of AAV-PHP.B., Ana Rita Batista, Oliver D King, Christopher P Reardon, Crystal Davis, Shankaracharya, Vivek M. Philip, Heather Gray-Edwards, Neil Aronin, Cathleen Lutz, John Landers, and Miguel Sena-Esteves
Methods for comparative ChIA-PET and Hi-C data analysis., Dan Capurso, Zhonghui Tang, and Yijun Ruan
Molecular and clonal evolution in recurrent metastatic gliosarcoma., Kevin J Anderson, Aaron C Tan, Jonathon Parkinson, Michael Back, Marina Kastelan, Allison Newey, Janice Brewer, Helen Wheeler, Amanda L Hudson, Samirkumar B Amin, Kevin C Johnson, Floris P Barthel, Roel G W Verhaak, and Mustafa Khasraw
Molecular Biology and Evolution of Cancer: From Discovery to Action., Jason A Somarelli, Heather Gardner, Vincent L Cannataro, Ella F Gunady, Amy M Boddy, Norman A Johnson, Jeffrey Nicholas Fisk, Stephen G Gaffney, Jeffrey Chuang, Sheng Li, Francesca D Ciccarelli, Anna R Panchenko, Kate Megquier, Sudhir Kumar, Alex Dornburg, James DeGregori, and Jeffrey P Townsend
Molecular profiling of CNS tumors for the treatment and management of disease., Qian Nie, Meng-Chang Hsiao, Harshpreet Chandok, Shannon Rowe, Matthew Prego, Bridgette Meyers, Gregory Omerza, Andrew N Hesse, Jasmina Uvalic, Melissa Soucy, Daniel Bergeron, Michael Peracchio, Shelbi Burns, Kevin Kelly, Jens Rueter, and Honey V Reddi
Mouse Phenome Database: a data repository and analysis suite for curated primary mouse phenotype data., Molly A. Bogue, Vivek M. Philip, David O Walton, Stephen C. Grubb, Matthew H Dunn, Georgi Kolishovski, Jake Emerson, Gaurab Mukherjee, Timothy M Stearns, Hao He, Vinita Sinha, Beena Kadakkuzha, Govindarajan Kunde-Ramamoorthy, and Elissa J Chesler
New statistical method identifies cytokines that distinguish stool microbiomes., Dake Yang, Jethro Johnson, Xin Zhou, Elena Deych, Berkley Shands, Blake Hanson, Erica Sodergren, George M. Weinstock, and William D Shannon
Nomenclature: Naming Your Gene-Modified Mouse., Alicia Valenzuela
Overlapping spectrums: The clinicogenetic commonalities between Charcot-Marie-Tooth and other neurodegenerative diseases., Paige B Martin, Amy N Hicks, Sarah E Holbrook, and Gregory A. Cox
Recovery of viable endocrine-specific cells and transcriptomes from human pancreatic islet-engrafted mice., Sambra D Redick, Linda Leehy, Ann R Rittenhouse, David M Blodgett, Alan G Derr, Alper Kucukural, Manuel G Garber, Leonard D. Shultz, Dale L Greiner, Jennifer P Wang, David M Harlan, Rita Bortell, and Agata Jurczyk
Sexual-dimorphism in human immune system aging., Eladio J Márquez, Cheng-Han Chung, Radu Marches, Robert J Rossi, Djamel Nehar-Belaid, Alper Eroglu, David J Mellert, George A Kuchel, Jacques Banchereau, and Duygu Ucar
Significantly different clinical phenotypes associated with mutations in synthesis and transamidase+remodeling glycosylphosphatidylinositol (GPI)-anchor biosynthesis genes., Leigh Carmody, Hannah Blau, Daniel Danis, Xingman A Zhang, Jean-Philippe Gourdine, Nicole Vasilevsky, Peter Krawitz, Miles D Thompson, and Peter N Robinson
Stimulus Complexity and Mouse Strain Drive Escalation of Operant Sensation Seeking Within and Across Sessions in C57BL/6J and DBA/2J Mice., Price E. Dickson and Guy Mittleman
Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable., Chunhua Dai, John T Walker, Alena Shostak, Ana Padgett, Erick Spears, Scott Wisniewski, Greg Poffenberger, Radhika Aramandla, E Danielle Dean, Nripesh Prasad, Shawn E Levy, Dale L Greiner, Leonard D. Shultz, Rita Bottino, and Alvin C Powers
The Deep Genome Project., K C Kent Lloyd, David J Adams, Gareth Baynam, Arthur L Beaudet, Fatima Bosch, Kym M Boycott, Robert E Braun, Mark Caulfield, Ronald Cohn, Mary E Dickinson, Michael S Dobbie, Ann M Flenniken, Paul Flicek, Sanjeev Galande, Xiang Gao, Anne Grobler, Jason D Heaney, Yann Herault, Martin Hrabě de Angelis, James R Lupski, Stanislas Lyonnet, Ann-Marie Mallon, Fabio Mammano, Calum A MacRae, Roderick McInnes, Colin McKerlie, Terrence F Meehan, Stephen A Murray, Lauryl M J Nutter, Yuichi Obata, Helen Parkinson, Michael S Pepper, Radislav Sedlacek, Je Kyung Seong, Toshihiko Shiroishi, Damian Smedley, Glauco Tocchini-Valentini, David Valle, Chi-Kuang Leo Wang, Sara Wells, Jacqueline K White, Wolfgang Wurst, Ying Xu, and Steve D M Brown
The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species., Kent A Shefchek, Nomi L Harris, Michael Gargano, Nicolas Matentzoglu, Deepak Unni, Matthew Brush, Daniel Keith, Tom Conlin, Nicole Vasilevsky, Xingmin Aaron Zhang, James P Balhoff, Larry Babb, Susan M. Bello, Hannah Blau, Yvonne Bradford, Seth Carbon, Leigh Carmody, Lauren E Chan, Valentina Cipriani, Alayne Cuzick, Maria D Rocca, Nathan Dunn, Shahim Essaid, Petra Fey, Chris Grove, Jean-Phillipe Gourdine, Ada Hamosh, Midori Harris, Ingo Helbig, Maureen Hoatlin, Marcin Joachimiak, Simon Jupp, Kenneth B Lett, Suzanna E Lewis, Craig McNamara, Zoë M Pendlington, Clare Pilgrim, Tim Putman, Vida Ravanmehr, Justin Reese, Erin Riggs, Sofia Robb, Paola Roncaglia, James Seager, Erik Segerdell, Morgan Similuk, Andrea L Storm, Courtney Thaxon, Anne Thessen, Julius O B Jacobsen, Julie A McMurry, Tudor Groza, Sebastian Köhler, Damian Smedley, Peter N Robinson, Christopher J Mungall, Melissa A Haendel, Monica C Munoz-Torres, and David Osumi-Sutherland
Treating Cancer as an Invasive Species., Javad Noorbakhsh, Zi-Ming Zhao, James C Russell, and Jeffrey H Chuang