Content Posted in 2017
27-Hydroxycholesterol induces hematopoietic stem cell mobilization and extramedullary hematopoiesis during pregnancy., Hideyuki Oguro, Jeffrey G McDonald, Zhiyu Zhao, Michihisa Umetani, Philip W Shaul, and Sean J Morrison
3D Axon Growth by Exogenous Electrical Stimulus and Soluble Factors., Min D Tang-Schomer
Abcc6 Knockout Rat Model Highlights the Role of Liver in PPi Homeostasis in Pseudoxanthoma Elasticum., Qiaoli Li, Joshua Kingman, Koen van de Wetering, Sami Tannouri, John P Sundberg, and Jouni Uitto
Abnormalities in the Structure and Function of Cerebellar Neurons and Neuroglia in the Lc/+ Chimeric Mouse Model of Variable Developmental Purkinje Cell Loss., James Cairns, Doug Swanson, Joanna Yeung, Anna Sinova, Ronny Chan, Praneetha Potluri, Price E. Dickson, Guy Mittleman, and Dan Goldowitz
Accumulating Evidence for Axonal Translation in Neuronal Homeostasis., Emily L Spaulding and Robert W. Burgess
A Cross-Species Analysis of Animal Models for the Investigation of Preterm Birth Mechanisms., Brian W Nielsen, Elizabeth A Bonney, Bradley D Pearce, Leah Rae Donahue, and Indra Neil Sarkar
Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective., Julia Chifman, Seda Arat, Zhiyong Deng, Erica Lemler, James C Pino, Leonard A Harris, Michael A Kochen, Carlos F Lopez, Steven A Akman, Frank M Torti, Suzy V Torti, and Reinhard Laubenbacher
ADAD2: a new player in RNA granule biology., Cassandra Rios
A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development., V Sivakamasundari, Petra Kraus, Wenjie Sun, Xiaoming Hu, Siew Lan Lim, Shyam Prabhakar, and Thomas Lufkin
Adolescent Obesity and Insulin Resistance: Roles of Ectopic Fat Accumulation and Adipose Inflammation., Sonia Caprio, Rachel Perry, and Romy Kursawe
Advances at the intersection of normal brain aging and Alzheimer's disease., Lynda A Wilmott, Sarah M Neuner, Corina Burger, and Catherine Kaczorowski
Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling., Chunhua Dai, Yan Hang, Alena Shostak, Greg Poffenberger, Nathaniel Hart, Nripesh Prasad, Neil Phillips, Shawn E Levy, Dale L Greiner, Leonard D. Shultz, Rita Bottino, Seung K Kim, and Alvin C Powers
Age exacerbates abnormal protein expression in a mouse model of Down syndrome., Md Mahiuddin Ahmed, Aaron Block, Suhong Tong, Muriel T. Davisson, and Katheleen J Gardiner
A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans., Patrick D Brophy, Maria Rasmussen, Mrutyunjaya Parida, Greg Bonde, Benjamin W Darbro, Xiaojing Hong, Jason C Clarke, Kevin A Peterson, James Denegre, Michael Schneider, Caroline R Sussman, Lone Sunde, Dorte L Lildballe, Jens Michael Hertz, Robert A Cornell, Stephen A. Murray, and J Robert Manak
A Guardian of the Heartbeat., Nadia Rosenthal
Albumin, in the Presence of Calcium, Elicits a Massive Increase in Extracellular Bordetella Adenylate Cyclase Toxin., Laura A Gonyar, Mary C Gray, Gregory J. Christianson, Borna Mehrad, and Erik L Hewlett
A license to cure?, Cathleen Lutz
Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics., Nigel G Kooreman, Patricia E de Almeida, Jonathan P Stack, Raman V Nelakanti, Sebastian Diecke, Ning-Yi Shao, Rutger-Jan Swijnenburg, Veronica Sanchez-Freire, Elena Matsa, Chun Liu, Andrew J Connolly, Jaap F Hamming, Paul H A Quax, Michael A Brehm, Dale L Greiner, Leonard D. Shultz, and Joseph C Wu
Alopecia areata., C Herbert Pratt, Lloyd E King, Andrew G Messenger, Angela M Christiano, and John P Sundberg
Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts., Nathan Lawlor, Ahrim Youn, Romy Kursawe, Duygu Ucar, and Michael L. Stitzel
Alternative splicing: approaching transcriptome complexity in human immune cell subsets., Christina Welch
A missense mutation in Grm6 reduces but does not eliminate mGluR6 expression or rod depolarizing bipolar cell function., Neal S Peachey, Nazarul Hasan, Bernie Fitzmaurice, Samantha Burrill, Gobinda Pangeni, Son Yong Karst, Laura G Reinholdt, Melissa L. Berry, Marjorie Strobel, Ronald G Gregg, Maureen A McCall, and Bo Chang
A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis., Alma-Martina Cepika, Romain Banchereau, Elodie Segura, Marina Ohouo, Brandi Cantarel, Kristina Goller, Victoria Cantrell, Emily Ruchaud, Elizabeth Gatewood, Phuong Nguyen, Jinghua Gu, Esperanza Anguiano, Sandra Zurawski, Jeanine M Baisch, Marilynn Punaro, Nicole Baldwin, Gerlinde Obermoser, Karolina Palucka, Jacques Banchereau, Sebastian Amigorena, and Virginia Pascual
A mutagenesis-derived Lrp5 mouse mutant with abnormal retinal vasculature and low bone mineral density., Jeremy R. Charette, Sarah E Earp, Brent A Bell, Cheryl L Ackert-Bicknell, Dana A Godfrey, Sujata Rao, Bela Anand-Apte, Patsy M. Nishina, and Neal S Peachey
A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers., MoonSun Jung, Amanda J Russell, Bing Liu, Joshy George, Pei Yan Liu, Tao Liu, Anna DeFazio, David D L Bowtell, André Oberthuer, Wendy B London, Jamie I Fletcher, Michelle Haber, Murray D Norris, and Michelle J Henderson
Analysis of autoreactive type one diabetes contributory CD8 T-cell frequencies in Nfkbid deficient NOD mice., Jennifer Allocco
Analysis of BMAA enantiomers in cycads, cyanobacteria, and mammals: in vivo formation and toxicity of D-BMAA., J S Metcalf, Doug Lobner, Sandra Anne Banack, Gregory A. Cox, Peter B Nunn, Peter B Wyatt, and Paul Alan Cox
Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice., Paul H Miller, Gabrielle Rabu, Margarita MacAldaz, David J H F Knapp, Alice M S Cheung, Kiran Dhillon, Naoto Nakamichi, Philip A Beer, Leonard D. Shultz, R Keith Humphries, and Connie J Eaves
Analysis of protein-coding genetic variation in 60,706 humans., Monkol Lek, Konrad J Karczewski, Eric V Minikel, Kaitlin E Samocha, Eric Banks, Timothy Fennell, Anne H O'Donnell-Luria, James S Ware, Andrew J Hill, Beryl B Cummings, Taru Tukiainen, Daniel P Birnbaum, Jack A Kosmicki, Laramie E Duncan, Karol Estrada, Fengmei Zhao, James Zou, Emma Pierce-Hoffman, Joanne Berghout, David N Cooper, Nicole Deflaux, Mark DePristo, Ron Do, Jason Flannick, Menachem Fromer, Laura Gauthier, Jackie Goldstein, Namrata Gupta, Daniel Howrigan, Adam Kiezun, Mitja I Kurki, Ami Levy Moonshine, Pradeep Natarajan, Lorena Orozco, Gina M Peloso, Ryan Poplin, Manuel A Rivas, Valentin Ruano-Rubio, Samuel A Rose, Douglas M Ruderfer, Khalid Shakir, Peter D Stenson, Christine Stevens, Brett P Thomas, Grace Tiao, Maria T Tusie-Luna, Ben Weisburd, Hong-Hee Won, Dongmei Yu, David M Altshuler, Diego Ardissino, Michael Boehnke, John Danesh, Stacey Donnelly, Roberto Elosua, Jose C Florez, Stacey B Gabriel, Gad Getz, Stephen J Glatt, Christina M Hultman, Sekar Kathiresan, Markku Laakso, Steven McCarroll, Mark I McCarthy, Dermot McGovern, Ruth McPherson, Benjamin M Neale, Aarno Palotie, Shaun M Purcell, Danish Saleheen, Jeremiah M Scharf, Pamela Sklar, Patrick F Sullivan, Jaakko Tuomilehto, Ming T Tsuang, Hugh C Watkins, James G Wilson, Mark J Daly, and Daniel G MacArthur
Analysis of the expression pattern of the Egr2-cre driver in the mouse brain during postnatal development., Kiersten Marr
An atypical role for the myeloid receptor Mincle in central nervous system injury., Thiruma V Arumugam, Silvia Manzanero, Milena B Furtado, Patrick J Biggins, Yu-Hsuan Hsieh, Mathias Gelderblom, Kelli Pa MacDonald, Ekaterina Salimova, Yu-I Li, Othmar Korn, Deborah Dewar, I Mhairi Macrae, Robert B Ashman, Sung-Chun Tang, Nadia Rosenthal, Marc J Ruitenberg, Tim Magnus, and Christine A Wells
Ancient hybridization and strong adaptation to viruses across African vervet monkey populations., Hannes Svardal, Anna J Jasinska, Cristian Apetrei, Giovanni Coppola, Yu Huang, Christopher A Schmitt, Beatrice Jacquelin, Vasily Ramensky, Michaela Müller-Trutwin, Martin Antonio, George M. Weinstock, J Paul Grobler, Ken Dewar, Richard K Wilson, Trudy R Turner, Wesley C Warren, Nelson B Freimer, and Magnus Nordborg
An evidence-based evaluation of transferrable skills and job satisfaction for science PhDs., Melanie Sinche, Rebekah L Layton, Patrick D Brandt, Anna B O'Connell, Joshua D Hall, Ashalla M Freeman, Jessica R Harrell, Jeanette Gowen Cook, and Patrick J Brennwald
An exploratory analysis of international mouse phenotyping consortium (IMPC) data., Stephen Price
Angiopoietin-1 is required for Schlemm's canal development in mice and humans., Benjamin R Thomson, Tomokazu Souma, Stuart W Tompson, Tuncer Onay, Krishnakumar Kizhatil, Owen M Siggs, Liang Feng, Kristina N Whisenhunt, Tammy L Yanovitch, Luba Kalaydjieva, Dimitar N Azmanov, Simone Finzi, Christine E Tanna, Alex W Hewitt, David A Mackey, Yasmin S Bradfield, Emmanuelle Souzeau, Shari Javadiyan, Janey L Wiggs, Francesca Pasutto, Xiaorong Liu, Simon W M John, Jamie E Craig, Jing Jin, Terri L Young, and Susan E Quaggin
A Novel Combination Treatment Targeting BCL-XL and MCL1 for KRAS/BRAF-mutated and BCL2L1-amplified Colorectal Cancers., Sung-Yup Cho, Jee Yun Han, Deukchae Na, Wonyoung Kang, Ahra Lee, Jooyoung Kim, Jieun Lee, Seoyeon Min, Jinjoo Kang, Jeesoo Chae, Jong-Il Kim, Hansoo Park, Won-Suk Lee, and Charles Lee
A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo., Mohit K Verma, Julia Clemens, Lisa M. Burzenski, Stephen B. Sampson, Michael A Brehm, Dale L Greiner, and Leonard D. Shultz
Antibiotic-associated Manipulation of the Gut Microbiota and Phenotypic Restoration in NOD Mice., James R Fahey, Bonnie L. Lyons, Haiyan L Olekszak, Anthony J Mourino, Jeremy Ratiu, Jeremy Racine, Harold D Chapman, David V. Serreze, Dina L Baker, and N Ken Hendrix
APOBEC1 complementation factor (A1CF) is dispensable for C-to-U RNA editing in vivo., Elizabeth Snyder, Christopher McCarty, Adrienne Mehalow, Karen L. Svenson, Stephen A. Murray, Ron Korstanje, and Robert E Braun
Application of the metabolic inhibitor 2-Deoxy-D-Glucose to treat autoimmune disease in mice., Rachel Burke
ARHGAP29 Mutation Is Associated with Abnormal Oral Epithelial Adhesions., B J Paul, Kristina Palmer, J C Sharp, C Herbert Pratt, Stephen A Murray, and M Dunnwald
Assessing the potential for raw meat to influence human colonization with Staphylococcus aureus., Margaret Carrel, Chang Zhao, Dipendra Thapaliya, Patrick Bitterman, Ashley E Kates, Blake M Hanson, and Tara C Smith
Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical Applications., Peter W Andrews, Uri Ben-David, Nissim Benvenisty, Peter Coffey, Kevin Eggan, Barbara B. Knowles, Andras Nagy, Martin Pera, Benjamin Reubinoff, Peter J Rugg-Gunn, and Glyn N Stacey
ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis., Zhaomin Li, Peng Zhang, Aimin Yan, Zhengyu Guo, Yuguang Ban, Jin Li, Shi Chen, Hui Yang, Yongzheng He, Jianping Li, Ying Guo, Wen Zhang, Ehsan Hajiramezanali, Huangda An, Darlene Fajardo, J William Harbour, Yijun Ruan, Stephen D Nimer, Peng Yu, Xi Chen, Mingjiang Xu, and Feng-Chun Yang
Atopy as a Modifier of the Relationships Between Endotoxin Exposure and Symptoms Among Laboratory Animal Workers., Ashley N Newton, Meghan Davis, Kirsten Koehler, Wayne Shreffler, Sharon Ahluwalia, Nervana Metwali, Peter S Thorne, Beverly J Paigen, and Elizabeth C Matsui
A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus., Tamara S Roman, Maren E Cannon, Swarooparani Vadlamudi, Martin L Buchkovich, Brooke N Wolford, Ryan P Welch, Mario A Morken, Grace J Kwon, Arushi Varshney, Romy Kursawe, Ying Wu, Anne U Jackson, Michael R Erdos, Johanna Kuusisto, Markku Laakso, Laura J Scott, Michael Boehnke, Francis S Collins, Stephen C J Parker, Michael L. Stitzel, and Karen L Mohlke
Auditory and otologic profile of Alström syndrome: Comprehensive single center data on 38 patients., Spencer Lindsey, Carmen Brewer, Olga Stakhovskaya, Hung Jeffrey Kim, Chris Zalewski, Joy Bryant, Kelly A King, Juergen K. Naggert, William A Gahl, Jan D Marshall, and Meral Gunay-Aygun
Barriers preventing the adoption of comprehensive cancer genomic profiling in the clinic., Cara M. Statz, Sara E. Patterson, and Susan Mockus
Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research., Teri A Manolio, Douglas M Fowler, Lea M Starita, Melissa A Haendel, Daniel G MacArthur, Leslie G Biesecker, Elizabeth Worthey, Rex L Chisholm, Eric D Green, Howard J Jacob, Howard L McLeod, Dan Roden, Laura Lyman Rodriguez, Marc S Williams, Gregory M Cooper, Nancy J Cox, Gail E Herman, Stephen Kingsmore, Cecilia Lo, Cathleen Lutz, Calum A MacRae, Robert L Nussbaum, Jose M Ordovas, Erin M Ramos, Peter N Robinson, Wendy S Rubinstein, Christine Seidman, Barbara E Stranger, Haoyi Wang, Monte Westerfield, and Carol J Bult
Behavioral Phenotyping Assays for Genetic Mouse Models of Neurodevelopmental, Neurodegenerative, and Psychiatric Disorders., Stacey J Sukoff Rizzo and Jacqueline N Crawley
Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy., Yanyan Peng, Deepali N Shinde, C Alexander Valencia, Jun-Song Mo, Jill Rosenfeld, Megan Truitt Cho, Adam Chamberlin, Zhuo Li, Jie Liu, Baoheng Gui, Rachel Brockhage, Alice Basinger, Brenda Alvarez-Leon, Peter Heydemann, Pilar L Magoulas, Andrea M Lewis, Fernando Scaglia, Solange Gril, Shuk Ching Chong, Matthew Bower, Kristin G Monaghan, Rebecca Willaert, Maria-Renee Plona, Rich Dineen, Francisca Milan, George Hoganson, Zoe Powis, Katherine L Helbig, Jennifer Keller-Ramey, Belinda S. Harris, Laura C. Anderson, Stacey J Sukoff Rizzo, Julie Kaylor, Jiani Chen, Min-Xin Guan, Elizabeth Sellars, Steven P Sparagana, James B Gibson, Laura G Reinholdt, Sha Tang, and Taosheng Huang
Biometric and structural ocular manifestations of Marfan syndrome., Petra Gehle, Barbara Goergen, Daniel Pilger, Peter Ruokonen, Peter N Robinson, and Daniel J Salchow
Building regression models for predicting age from human blood epigenomes profiled with the ATAC-seq technology., Gokul Parakulam
Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity., George L. Sutphin, Grant Backer, Susan Sheehan, Shannon Bean, Caroline Corban, Teresa Liu, Marjolein J Peters, Joyce B J van Meurs, Joanne M Murabito, Andrew D Johnson, and Ron Korstanje
Canine Brachycephaly Is Associated with a Retrotransposon-Mediated Missplicing of SMOC2., Thomas W Marchant, Edward J Johnson, Lynn McTeir, Craig I Johnson, Adam Gow, Tiziana Liuti, Dana Kuehn, Karen L. Svenson, Mairead L Bermingham, Michaela Drögemüller, Marc Nussbaumer, Megan G Davey, David J Argyle, Roger M Powell, Sérgio Guilherme, Johann Lang, Gert Ter Haar, Tosso Leeb, Tobias Schwarz, Richard J Mellanby, Dylan N Clements, and Jeffrey J Schoenebeck
Cardiac regeneration: All work and no repair?, Teresa Kennedy-Lydon and Nadia Rosenthal
Ceftaroline-Resistant, Daptomycin-Tolerant, and Heterogeneous Vancomycin-Intermediate Methicillin-Resistant Staphylococcus aureus Causing Infective Endocarditis., Masayuki Nigo, Lorena Diaz, Lina P Carvajal, Truc T Tran, Rafael Rios, Diana Panesso, Juan D Garavito, William R Miller, Audrey Wanger, George M. Weinstock, Jose M Munita, Cesar A Arias, and Henry F Chambers
Cerebellar contribution to higher and lower order rule learning and cognitive flexibility in mice., Price E. Dickson, J Cairns, D Goldowitz, and G Mittleman
Characteristics of cardiomyopathy in Alström syndrome: Prospective single-center data on 38 patients., Alessandra Brofferio, Vandana Sachdev, Hwaida Hannoush, Jan D. Marshall, Juergen K. Naggert, Stanislav Sidenko, Anna Noreuil, Arlene Sirajuddin, Joy Bryant, Joan C Han, Andrew E Arai, William A Gahl, and Meral Gunay-Aygun
Characterization of Crichton mutation leading to age-dependent, behavioral phenotypes., Molly Herman
Chasing the recipe for a pro-regenerative immune system., James W Godwin, Alexander R Pinto, and Nadia A Rosenthal
Chromatin interaction networks revealed unique connectivity patterns of broad H3K4me3 domains and super enhancers in 3D chromatin., Asa Thibodeau, Eladio J Marquez, Dong-Guk Shin, Paola Vera-Licona, and Duygu Ucar
CloudNeo: A cloud pipeline for identifying patient-specific tumor neoantigens., Preeti Bais, Sandeep Namburi, Daniel M. Gatti, Xinyu Zhang, and Jeffrey Chuang
Combination of IL-10 and IL-2 induces oligoclonal human CD4 T cell expansion during xenogeneic and allogeneic GVHD in humanized mice., Sojan Abraham, Hua Guo, Jang-Gi Choi, Chunting Ye, Midhun Ben Thomas, Nora Ortega, Alok Dwivedi, N Manjunath, Guohua Yi, and Premlata Shankar
Combinatorial Ranking of Gene Sets to Predict Disease Relapse: The Retinoic Acid Pathway in Early Prostate Cancer., Hieu T Nim, Milena B Furtado, Mirana Ramialison, and Sarah E Boyd
Communicating science at The Jackson Laboratory, Tamsyn Brann
Community characteristics of the gut microbiomes of competitive cyclists., Lauren M Petersen, Eddy J Bautista, Hoan Nguyen, Blake M Hanson, Lei Chen, Sai H Lek, Erica Sodergren Weinstock, and George M. Weinstock
Comparative genomics to determine the genotype responsible for a bacillus subtilis mutant phenotype., Amber Acquaye
Computational Prediction of Position Effects of Apparently Balanced Human Chromosomal Rearrangements., Cinthya J Zepeda-Mendoza, Jonas Ibn-Salem, Tammy Kammin, David J Harris, Debra Rita, Karen W Gripp, Jennifer J MacKenzie, Andrea Gropman, Brett Graham, Ranad Shaheen, Fowzan S Alkuraya, Campbell K Brasington, Edward J Spence, Diane Masser-Frye, Lynne M Bird, Erica Spiegel, Rebecca L Sparkes, Zehra Ordulu, Michael E Talkowski, Miguel A Andrade-Navarro, Peter N Robinson, and Cynthia C Morton
Concerted effects of heterogeneous nuclear ribonucleoprotein C1/C2 to control vitamin D-directed gene transcription and RNA splicing in human bone cells., Rui Zhou, Juw Won Park, Rene F Chun, Thomas S Lisse, Alejandro J Garcia, Kathryn Zavala, Jessica L Sea, Zhi-Xiang Lu, Jianzhong Xu, John S Adams, Yi Xing, and Martin Hewison
Confined placental mosaicism for 22q11.2 deletion as the etiology for discordant positive NIPT results., M Bunnell, Chengsheng Zhang, Charles Lee, D W Bianchi, and L Wilkins-Haug
Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice., Bixuan Lin, Ashley E Ciecko, Erin MacKinney, David V. Serreze, and Yi-Guang Chen
Constitutive resistance to viral infection in human CD141+ dendritic cells., Aymeric Silvin, Chun I. Yu, Xavier Lahaye, Francesco Imperatore, Jean-Baptiste Brault, Sylvain Cardinaud, Christian Becker, Wing-Hong Kwan, Cecile Conrad, Mathieu Maurin, Christel Goudot, Santy Marques-Ladeira, Yuanyuan Wang, Virginia Pascual, Esperanza Anguiano, Randy A. Albrecht, Matteo Iannacone, Adolfo Garcia-Sastre, Bruno Goud, Marc Dalod, Arnaud Moris, Meriam Merad, A. Karolina Palucka, and Nicholas Manel
Continuous Glucose Monitoring in Female NOD Mice Reveals Daily Rhythms and a Negative Correlation With Body Temperature., Ron Korstanje, Jennifer L Ryan, Holly S Savage, Bonnie L. Lyons, Kevin G Kane, and Stacey J Sukoff Rizzo
Cre-loxP-Mediated Recombination: General Principles and Experimental Considerations., Michael A McLellan, Nadia A Rosenthal, and Alexander R Pinto
Crimean-Congo Hemorrhagic Fever in Humanized Mice Reveals Glial Cells as Primary Targets of Neurological Infection., Jessica R Spengler, M Kelly Keating, Anita K McElroy, Marko Zivcec, JoAnn D Coleman-McCray, Jessica R Harmon, Brigid C Bollweg, Cynthia S Goldsmith, Éric Bergeron, James G. Keck, Sherif R Zaki, Stuart T Nichol, and Christina F Spiropoulou
CRISPR-Cas9-mediated multiplex gene editing in CAR-T cells., Xiaojuan Liu, Yongping Zhang, Chen Cheng, Albert Cheng, Xingying Zhang, Na Li, Changqing Xia, Xiaofei Wei, Xiang Liu, and Haoyi Wang
CRISPRtools: a flexible computational platform for performing CRISPR/Cas9 experiments in the mouse., Kevin A Peterson, Glen L Beane, Leslie Goodwin, Peter Kutny, Laura G Reinholdt, and Stephen A. Murray
Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating., Stacey L Kirkpatrick, Lisa R Goldberg, Neema Yazdani, R Keith Babbs, Jiayi Wu, Eric R Reed, David F Jenkins, Amanda F Bolgioni, Kelsey I Landaverde, Kimberly P Luttik, Karen S Mitchell, Vivek Kumar, W Evan Johnson, Megan K Mulligan, Pietro Cottone, and Camron D Bryant
Data integration & analysis of the epigenetics of drug and alcohol dependence: an application of GeneWeaver., Nkima J Stephenson
Deconvolution of DNA methylation identifies differentially methylated gene regions on 1p36 across breast cancer subtypes., Alexander J Titus, Gregory P Way, Kevin C Johnson, and Brock C Christensen
Defining Disease, Diagnosis, and Translational Medicine within a Homeostatic Perturbation Paradigm: The National Institutes of Health Undiagnosed Diseases Program Experience., Timothy Gall, Elise Valkanas, Christofer Bello, Thomas Markello, Christopher Adams, William P Bone, Alexander J Brandt, Jennifer M Brazill, Lynn Carmichael, Mariska Davids, Joie Davis, Zoraida Diaz-Perez, David Draper, Jeremy Elson, Elise D Flynn, Rena Godfrey, Catherine Groden, Cheng-Kang Hsieh, Roxanne Fischer, Gretchen A Golas, Jessica Guzman, Yan Huang, Megan S Kane, Elizabeth Lee, Chong Li, Amanda E Links, Valerie Maduro, May Christine V Malicdan, Fayeza S Malik, Michele Nehrebecky, Joun Park, Paul Pemberton, Katherine Schaffer, Dimitre Simeonov, Murat Sincan, Damian Smedley, Zaheer Valivullah, Colleen Wahl, Nicole Washington, Lynne A Wolfe, Karen Xu, Yi Zhu, William A Gahl, Cynthia J Tifft, Camillo Toro, David R Adams, Miao He, Peter N Robinson, Melissa A Haendel, R Grace Zhai, and Cornelius F Boerkoel
Determination of the mutation responsible for tachycardia in ENU mutant strain HLB468., Emma Anderson
Determining the genetic framework of hereditary deafness using bioinformatics., Alina K. Andrews
Determining the relationship between spermatogonial stem cells and blood vessels in mouse testis., Yuzhao Hu
Development of Humanized Mice in the Age of Genome Editing., Vishnu Hosur, Benjamin E. Low, Cindy Avery, Leonard D. Shultz, and Michael V. Wiles
Discovering the role of pathogenic BRCA1 mutations in tandem duplicator phenotype development., Conner Lajoie
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium., Terrence F Meehan, Nathalie Conte, David B West, Julius O Jacobsen, Jeremy Mason, Jonathan Warren, Chao-Kung Chen, Ilinca Tudose, Mike Relac, Peter Matthews, Natasha Karp, Luis Santos, Tanja Fiegel, Natalie Ring, Henrik Westerberg, Simon Greenaway, Duncan Sneddon, Hugh Morgan, Gemma F Codner, Michelle E Stewart, James Brown, Neil Horner, Melissa Haendel, Nicole Washington, Christopher J Mungall, Corey L Reynolds, Juan Gallegos, Valerie Gailus-Durner, Tania Sorg, Guillaume Pavlovic, Lynette R Bower, Mark Moore, Iva Morse, Xiang Gao, Glauco P Tocchini-Valentini, Yuichi Obata, Soo Young Cho, Je Kyung Seong, John Seavitt, Arthur L Beaudet, Mary E Dickinson, Yann Herault, Wolfgang Wurst, Martin Hrabe de Angelis, K C Kent Lloyd, Ann M Flenniken, Lauryl M J Nutter, Susan Newbigging, Colin McKerlie, Monica J Justice, Stephen A. Murray, Karen L. Svenson, Robert E Braun, Jacqueline K White, Allan Bradley, Paul Flicek, Sara Wells, William C Skarnes, David J Adams, Helen Parkinson, Ann-Marie Mallon, Steve D M Brown, and Damian Smedley
Downregulation of miR-33a-5p in Hepatocellular Carcinoma: A Possible Mechanism for Chemotherapy Resistance., Wei Meng, Yan Tai, Hui Zhao, Binsheng Fu, Tong Zhang, Wei Liu, Hua Li, Yang Yang, Qi Zhang, Yuliang Feng, and Guihua Chen
Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective., Jeffrey M. Harder, Catherine E. Braine, Pete A. Williams, Xianjun Zhu, Katharine H Macnicoll, Gregory L Sousa, Rebecca A Buchanan, Richard S Smith, Richard T Libby, Gareth R Howell, and Simon W M John
Early induction of NRF2 antioxidant pathway by RHBDF2 mediates rapid cutaneous wound healing., Vishnu Hosur, Lisa M. Burzenski, Timothy M Stearns, Michelle L Farley, John P Sundberg, Michael V. Wiles, and Leonard D. Shultz
Editorial overview: Characterizing the cancer genome: mechanistic insights and translational opportunities., Olivier Delattre and Carol J Bult
Effective biomedical document classification for identifying publications relevant to the mouse Gene Expression Database (GXD)., Xiangying Jiang, Martin Ringwald, Judith A. Blake, and Hagit Shatkay
Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains., Kenneth R. Johnson, Cong Tian, Leona H. Gagnon, Haiyan Jiang, Dalian Ding, and Richard Salvi
Effects of research complexity and competition on the incidence and growth of coauthorship in biomedicine., Jason Cory Brunson, Xiaoyan Wang, and Reinhard Laubenbacher
EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas., Dariush Etemadmoghadam, Walid J Azar, Ying Lei, Tania Moujaber, Dale W Garsed, Catherine J Kennedy, Sian Fereday, Chris Mitchell, Yoke-Eng Chiew, Joy Hendley, Raghwa Sharma, Paul R Harnett, Jason Li, Elizabeth L Christie, Ann-Marie Patch, Joshy George, George Au-Yeung, Gisela Mir Arnau, Timothy P Holloway, Timothy Semple, John V Pearson, Nicola Waddell, Sean M Grimmond, Martin Köbel, Helen Rizos, Ivan B Lomakin, David D L Bowtell, and Anna deFazio
Elucidating retinal transcripts correlated with changes in the aging brain of an Alzheimer's mouse model., Julia Huesa
Embryogenesis in a dish., Martin Pera
EMT/MET at the Crossroad of Stemness, Regeneration and Oncogenesis: The Ying-Yang Equilibrium Recapitulated in Cell Spheroids., Elvira Forte, Isotta Chimenti, Paolo Rosa, Francesco Angelini, Francesca Pagano, Antonella Calogero, Alessandro Giacomello, and Elisa Messina
Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer., Hengyu Lu, Nicole Villafane, Turgut Dogruluk, Caitlin L Grzeskowiak, Kathleen Kong, Yiu Huen Tsang, Oksana Zagorodna, Angeliki Pantazi, Lixing Yang, Nicholas J Neill, Young Won Kim, Chad J Creighton, Roel G W Verhaak, Gordon B Mills, Peter J Park, Raju Kucherlapati, and Kenneth L Scott
EphB4/EphrinB2 therapeutics in Rhabdomyosarcoma., Matthew E Randolph, Megan M Cleary, Zia Bajwa, Matthew N Svalina, Michael C Young, Atiya Mansoor, Pali Kaur, Carol J Bult, Martin W Goros, Joel E Michalek, Sunny Xiang, James G. Keck, Valery Krasnoperov, Parkash Gill, and Charles Keller
Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice., Jiang Wei Wu, Christoph Preuss, Shu Pei Wang, Hao Yang, Bo Ji, Gregory W. Carter, Rebecca Gladdy, Gregor Andelfinger, and Grant A Mitchell
Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice., Anna L. Tyler, Bo Ji, Daniel M. Gatti, Steven C. Munger, Gary A. Churchill, Karen L. Svenson, and Gregory W. Carter
Establishing a role for the kinesin-8 superfamily member Kif18a during cell migration., Ashley Hudson
Evolutionarily Conserved Principles Predict 3D Chromatin Organization., M Jordan Rowley, Michael H Nichols, Xiaowen Lyu, Masami Ando-Kuri, I Sarahi M Rivera, Karen Hermetz, Ping Wang, Yijun Ruan, and Victor G Corces
Examining expression of Scgb1c1 in developing and adult murine hearts., Adam Fasman
Expression and function of ABCG2 and XIAP in glioblastomas., Ivette F Emery, Archana Gopalan, Stephanie Wood, Kin-Hoe Chow, Chiara Battelli, Joshy George, Hagen Blaszyk, Jeffrey Florman, and Kyuson Yun
Factors influencing the infant gut microbiome at age 3-6 months: Findings from the ethnically diverse Vitamin D Antenatal Asthma Reduction Trial (VDAART)., Joanne E Sordillo, Yanjiao Zhou, Michael J McGeachie, John Ziniti, Nancy Lange, Nancy Laranjo, Jessica R Savage, Vincent Carey, George O'Connor, Megan Sandel, Robert Strunk, Leonard Bacharier, Robert Zeiger, Scott T Weiss, George M. Weinstock, Diane R Gold, and Augusto A Litonjua
Finger stick blood collection for gene expression profiling and storage of tempus blood RNA tubes., Darawan Rinchai, Esperanza Anguiano, Phuong Nguyen, and Damien Chaussabel
Forward-genetics analysis of sleep in randomly mutagenized mice., Hiromasa Funato, Chika Miyoshi, Tomoyuki Fujiyama, Takeshi Kanda, Makito Sato, Zhiqiang Wang, Jing Ma, Shin Nakane, Jun Tomita, Aya Ikkyu, Miyo Kakizaki, Noriko Hotta-Hirashima, Satomi Kanno, Haruna Komiya, Fuyuki Asano, Takato Honda, Staci J Kim, Kanako Harano, Hiroki Muramoto, Toshiya Yonezawa, Seiya Mizuno, Shinichi Miyazaki, Linzi Connor, Vivek Kumar, Ikuo Miura, Tomohiro Suzuki, Atsushi Watanabe, Manabu Abe, Fumihiro Sugiyama, Satoru Takahashi, Kenji Sakimura, Yu Hayashi, Qinghua Liu, Kazuhiko Kume, Shigeharu Wakana, Joseph S Takahashi, and Masashi Yanagisawa
From function to dysfunction: gene ontology and cancer., Yoojin Cha
Functional interrogation of human T cell co-stimulatory molecules., Jordana Graveley
Gene mapping of glaucoma related phenotypes in a forward genetics ENU screen., Sherley Collado-Justiniano
Generating CRISPR mouse models: challenges and solutions., Rudolf Jaenisch and David S Grass
Genetic and epigenetic heterogeneity and the impact on cancer relapse., Ciaran Hassan, Ebrahim Afshinnekoo, Sheng Li, Shixiu Wu, and Christopher E Mason
Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes., Jeremy Ratiu, Jeremy Racine, Muneer G. Hasham, Qiming Wang, Jane Branca, Harold D Chapman, Jing Zhu, Nina M. Donghia, Vivek M. Philip, William H. Schott, Clive Wasserfall, Mark A Atkinson, Kevin D Mills, Caroline M Leeth, and David V. Serreze
Genetic Contributors to Intergenerational CAG Repeat Instability in Huntington's Disease Knock-In Mice., João Luís Neto, Jong-Min Lee, Ali Afridi, Tammy Gillis, Jolene R Guide, Stephani Dempsey, Brenda Lager, Isabel Alonso, Vanessa C Wheeler, and Ricardo Mouro Pinto
Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis., Vishnu Hosur, Benjamin E. Low, Leonard D. Shultz, and Michael V. Wiles
Genetic interactions improve models of quantitative traits., Anna L. Tyler and Gregory W. Carter
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes., Arushi Varshney, Laura J Scott, Ryan P Welch, Michael R Erdos, Peter S Chines, Narisu Narisu, Ricardo D'O Albanus, Peter Orchard, Brooke N Wolford, Romy Kursawe, Swarooparani Vadlamudi, Maren E Cannon, John P Didion, John Hensley, Anthony Kirilusha, Lori L Bonnycastle, D Leland Taylor, Richard Watanabe, Karen L Mohlke, Michael Boehnke, Francis S Collins, Stephen C J Parker, and Michael L. Stitzel
Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice., Simon D Pouwels, Alen Faiz, Lisette E den Boef, Reneé Gras, Maarten van den Berge, H Marike Boezen, Ron Korstanje, Nick H T Ten Hacken, Antoon J M van Oosterhout, Irene H Heijink, and Martijn C Nawijn
Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate., Anna J Jasinska, Ivette Zelaya, Susan K Service, Christine B Peterson, Rita M Cantor, Oi-Wa Choi, Joseph DeYoung, Eleazar Eskin, Lynn A Fairbanks, Scott Fears, Allison E Furterer, Yu S Huang, Vasily Ramensky, Christopher A Schmitt, Hannes Svardal, Matthew J Jorgensen, Jay R Kaplan, Diego Villar, Bronwen L Aken, Paul Flicek, Rishi Nag, Emily S Wong, John Blangero, Thomas D Dyer, Marina Bogomolov, Yoav Benjamini, George M. Weinstock, Ken Dewar, Chiara Sabatti, Richard K Wilson, J David Jentsch, Wesley Warren, Giovanni Coppola, Roger P Woods, and Nelson B Freimer
Genomes of the Mouse Collaborative Cross., Anuj Srivastava, Andrew P Morgan, Maya L Najarian, Vishal Kumar Sarsani, J Sebastian Sigmon, John R Shorter, Anwica Kashfeen, Rachel C McMullan, Lucy H Williams, Paola Giusti-Rodríguez, Martin T Ferris, Patrick Sullivan, Pablo Hock, Darla R Miller, Timothy A Bell, Leonard McMillan, Gary A. Churchill, and Fernando Pardo-Manuel de Villena
Genome-Wide Analysis of Protein-Coding Variants in Leprosy., Hong Liu, Zhenzhen Wang, Yi Li, Gongqi Yu, Xi'an Fu, Chuan Wang, Wenting Liu, Yongxiang Yu, Fangfang Bao, Astrid Irwanto, Jian Liu, Tongsheng Chu, Anand Kumar Andiappan, Sebastian Maurer-Stroh, Vachiranee Limviphuvadh, Honglei Wang, Zihao Mi, Yonghu Sun, Lele Sun, Ling Wang, Chaolong Wang, Jiabao You, Jinghui Li, Jia Nee Foo, Herty Liany, Wee Yang Meah, Guiye Niu, Zhenhua Yue, Qing Zhao, Na Wang, Meiwen Yu, Wenjun Yu, Xiujun Cheng, Chiea Chuen Khor, Kar Seng Sim, Tin Aung, Ningli Wang, Deyun Wang, Li Shi, Yong Ning, Zhongyi Zheng, Rongde Yang, Jinlan Li, Jun Yang, Liangbin Yan, Jianping Shen, Guocheng Zhang, Shumin Chen, Jianjun Liu, and Furen Zhang
Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia., M P Hanley, M A Hahn, A X Li, X Wu, Jianan Lin, J Wang, A H Choi, Zhengqing Ouyang, Y Fong, G P Pfeifer, T J Devers, and D W Rosenberg
Genome-wide enrichment of damaging de novo variants in patients with isolated and complex congenital diaphragmatic hernia., Mauro Longoni, Frances A High, Hongjian Qi, Maliackal P Joy, Regis Hila, Caroline M Coletti, Julia Wynn, Maria Loscertales, Linshan Shan, Carol J Bult, Jay M Wilson, Yufeng Shen, Wendy K Chung, and Patricia K Donahoe
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis., Frank J A van Rooij, Rehan Qayyum, Albert V Smith, Yi Zhou, Stella Trompet, Toshiko Tanaka, Margaux F Keller, Li-Ching Chang, Helena Schmidt, Min-Lee Yang, Ming-Huei Chen, James Hayes, Andrew D Johnson, Lisa R Yanek, Christian Mueller, Leslie Lange, James S Floyd, Mohsen Ghanbari, Alan B Zonderman, J Wouter Jukema, Albert Hofman, Cornelia M van Duijn, Karl C Desch, Yasaman Saba, Ayse B Ozel, Beverly M Snively, Jer-Yuarn Wu, Reinhold Schmidt, Myriam Fornage, Robert J Klein, Caroline S Fox, Koichi Matsuda, Naoyuki Kamatani, Philipp S Wild, David J Stott, Ian Ford, P Eline Slagboom, Jaden Yang, Audrey Y Chu, Amy J Lambert, André G Uitterlinden, Oscar H Franco, Edith Hofer, David Ginsburg, Bella Hu, Brendan Keating, Ursula M Schick, Jennifer A Brody, Jun Z Li, Zhao Chen, Tanja Zeller, Jack M Guralnik, Daniel I Chasman, Luanne L. Peters, Michiaki Kubo, Diane M Becker, Jin Li, Gudny Eiriksdottir, Jerome I Rotter, Daniel Levy, Vera Grossmann, Kushang V Patel, Chien-Hsiun Chen, Paul M Ridker, Hua Tang, Lenore J Launer, Kenneth M Rice, Ruifang Li-Gao, Luigi Ferrucci, Michelle K Evans, Avik Choudhuri, Eirini Trompouki, Brian J Abraham, Song Yang, Atsushi Takahashi, Yoichiro Kamatani, Charles Kooperberg, Tamara B Harris, Sun Ha Jee, Josef Coresh, Fuu-Jen Tsai, Dan L Longo, Yuan-Tsong Chen, Janine F Felix, Qiong Yang, Bruce M Psaty, Eric Boerwinkle, Lewis C Becker, Dennis O Mook-Kanamori, James G Wilson, Vilmundur Gudnason, Christopher J O'Donnell, Abbas Dehghan, L Adrienne Cupples, Michael A Nalls, Andrew P Morris, Yukinori Okada, Alexander P Reiner, Leonard I Zon, and Santhi K Ganesh
Genomic analyses of primitive, wild and cultivated citrus provide insights into asexual reproduction., Xia Wang, Yuantao Xu, Siqi Zhang, Li Cao, Yue Huang, Junfeng Cheng, Guizhi Wu, Shilin Tian, Chunli Chen, Yan Liu, Huiwen Yu, Xiaoming Yang, Hong Lan, Nan Wang, Lun Wang, Jidi Xu, Xiaolin Jiang, Zongzhou Xie, Meilian Tan, Robert M Larkin, Ling-Ling Chen, Bin-Guang Ma, Yijun Ruan, Xiuxin Deng, and Qiang Xu
Genomics of Islet (Dys)function and Type 2 Diabetes., Nathan Lawlor, Shubham Khetan, Duygu Ucar, and Michael L. Stitzel
Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma., Pete A. Williams, Jeffrey M. Harder, and Simon W M John
Glioma: experimental models and reality., Krissie Lenting, Roel G W Verhaak, Mark Ter Laan, Pieter Wesseling, and William Leenders
GlioVis data portal for visualization and analysis of brain tumor expression datasets., Robert L Bowman, Qianghu Wang, Angel Carro, Roel G W Verhaak, and Massimo Squatrito
GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma., Pete A. Williams, Catherine E Braine, Nicole E Foxworth, Kelly E Cochran, and Simon W M John
Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA., Walter K Mowel, Sam J McCright, Jonathan J Kotzin, Magalie A Collet, Asli Uyar, Xin Chen, Alexandra DeLaney, Sean P Spencer, Anthony T Virtue, EnJun Yang, Alejandro Villarino, Makoto Kurachi, Margaret C Dunagin, Gretchen Harms Pritchard, Judith Stein, Cynthia Hughes, Diogo Fonseca-Pereira, Henrique Veiga-Fernandes, Arjun Raj, Taku Kambayashi, Igor E Brodsky, John J O'Shea, E John Wherry, Loyal A Goff, John L Rinn, Adam Williams, Richard A Flavell, and Jorge Henao-Mejia
Hearing loss without overt metabolic acidosis in ATP6V1B1 deficient MRL mice, a new genetic model for non-syndromic deafness with enlarged vestibular aqueducts., Cong Tian, Leona H. Gagnon, Chantal M. Longo-Guess, Ron Korstanje, Susan Sheehan, Kevin K Ohlemiller, Angela D Schrader, Jaclynn M Lett, and Kenneth R. Johnson
Heart regeneration in the salamander relies on macrophage-mediated control of fibroblast activation and the extracellular landscape., James W Godwin, R Debuque, E Salimova, and Nadia A Rosenthal
Heightened human red blood cell survival in genetically and chemically engineered next generation NSG mice., Cedric Lozano
Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury., Michal Pyzik, Timo Rath, Timothy T Kuo, Sanda Win, Kristi Baker, Jonathan J Hubbard, Rosa Grenha, Amit Gandhi, Thomas D Krämer, Adam R Mezo, Zachary S Taylor, Kevin McDonnell, Vicki Nienaber, Jan Terje Andersen, Atsushi Mizoguchi, Laurence Blumberg, Shalaka Purohit, Susan D Jones, Gregory J. Christianson, Wayne I Lencer, Inger Sandlie, Neil Kaplowitz, Derry C. Roopenian, and Richard S Blumberg
High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients., Sung-Yup Cho, Changho Park, Deukchae Na, Jee Yun Han, Jieun Lee, Ok-Kyoung Park, Chengsheng Zhang, Chang Ohk Sung, Hyo Eun Moon, Yona Kim, Jeong Hoon Kim, Jong Jae Kim, Shin Kwang Khang, Do-Hyun Nam, Jung Won Choi, Yeon-Lim Suh, Dong Gyu Kim, Sung Hye Park, Hyewon Youn, Kyuson Yun, Jong-Il Kim, Charles Lee, Sun Ha Paek, and Hansoo Park
High-Resolution Maps of Mouse Reference Populations., Petr Simecek, Jiri Forejt, Robert W Williams, Toshihiko Shiroishi, Toyoyuki Takada, Lu Lu, Thomas E Johnson, Beth Bennett, Christian F Deschepper, Marie-Pier Scott-Boyer, Fernando Pardo-Manuel de Villena, and Gary A Churchill
HIV-Infected Children Have Elevated Levels of PD-1+ Memory CD4 T Cells With Low Proliferative Capacity and High Inflammatory Cytokine Effector Functions., Julia Foldi, Lina Kozhaya, Bret McCarty, Mussa Mwamzuka, Fatma Marshed, Tiina Ilmet, Max Kilberg, Adam Kravietz, Aabid Ahmed, William Borkowsky, Derya Unutmaz, and Alka Khaitan
How mice are indispensable for understanding obesity and diabetes genetics., Alan D Attie, Gary A Churchill, and Joseph H Nadeau
Human embryo research and the 14-day rule., Martin Pera
Humanized Mouse Models of Clinical Disease., Nicole C Walsh, Laurie L Kenney, Sonal Jangalwe, Ken-Edwin Aryee, Dale L Greiner, Michael A Brehm, and Leonard D. Shultz
Hypoxic HepG2 cell adaptation decreases ATP synthase dimers and ATP production in inflated cristae by mitofilin down-regulation concomitant to MICOS clustering., Lydie Plecitá-Hlavatá, Hana Engstová, Lukáš Alán, Tomáš Špaček, Andrea Dlasková, Katarína Smolková, Jitka Špačková, Jan Tauber, Vendula Strádalová, Jan Malínský, Mark Lessard, Joerg Bewersdorf, and Petr Ježek
I-ATAC: interactive pipeline for the management and pre-processing of ATAC-seq samples., Zeeshan Ahmed and Duygu Ucar
IGF-1 and healthy aging., Madeline Williams
IKKα regulates human keratinocyte migration through surveillance of the redox environment., Thomas S lisse and Sandra Rieger
Imbalance-Aware Machine Learning for Predicting Rare and Common Disease-Associated Non-Coding Variants., Max Schubach, Matteo Re, Peter N Robinson, and Giorgio Valentini
Immunotherapy: Cancer vaccines on the move., Jacques Banchereau and Karolina Palucka
Impact of Age, Caloric Restriction, and Influenza Infection on Mouse Gut Microbiome: An Exploratory Study of the Role of Age-Related Microbiome Changes on Influenza Responses., Jenna M Bartley, Xin Zhou, George A Kuchel, George M. Weinstock, and Laura Haynes
Improved in vitro fertilization via zona thinning., JAX Mice Clinical and Research services
Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-α2 Related Congenital Muscular Dystrophy., Raffaella Willmann, Heather Gordish-Dressman, Sarina Meinen, Markus A Rüegg, Qing Yu, Kanneboyina Nagaraju, Ayar Kumar, Mahasweta Girgenrath, Caroline B M Coffey, Vivian Cruz, Pam M Van Ry, Laurent P. Bogdanik, Cathleen Lutz, Anne Rutkowski, and Dean J Burkin
Influenza vaccines differentially regulate the interferon response in human dendritic cell subsets., Shruti Athale, Romain Banchereau, LuAnn Thompson-Snipes, Yuanyuan Wang, Karolina Palucka, Virginia Pascual, and Jacques Banchereau
Innovating high school genomic education with hands-on and classroom teaching methods., Ashley Greaves
Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice., Emilia Peuhu, Siiri I Salomaa, Nicola De Franceschi, Christopher S Potter, John P Sundberg, and Jeroen Pouwels
Interferon-γ Limits Diabetogenic CD8(+) T-Cell Effector Responses in Type 1 Diabetes., John P Driver, Jeremy Racine, Cheng Ye, Deanna J Lamont, Brittney N Newby, Caroline M. Leeth, Harold D. Chapman, Todd M Brusko, Yi-Guang Chen, Clayton E Mathews, and David V. Serreze
International Cooperation to Enable the Diagnosis of All Rare Genetic Diseases., Kym M Boycott, Ana Rath, Jessica X Chong, Taila Hartley, Fowzan S Alkuraya, Gareth Baynam, Anthony J Brookes, Michael Brudno, Angel Carracedo, Johan T den Dunnen, Stephanie O M Dyke, Xavier Estivill, Jack Goldblatt, Catherine Gonthier, Stephen C Groft, Ivo Gut, Ada Hamosh, Philip Hieter, Sophie Höhn, Matthew E Hurles, Petra Kaufmann, Bartha M Knoppers, Jeffrey P Krischer, Milan Macek, Gert Matthijs, Annie Olry, Samantha Parker, Justin Paschall, Anthony A Philippakis, Heidi L Rehm, Peter N Robinson, Pak-Chung Sham, Rumen Stefanov, Domenica Taruscio, Divya Unni, Megan R Vanstone, Feng Zhang, Han Brunner, Michael J Bamshad, and Hanns Lochmüller
Interrogating the topological robustness of gene regulatory circuits by randomization., Bin Huang, Mingyang Lu, Dongya Jia, Eshel Ben-Jacob, Herbert Levine, and Jose N Onuchic
Introduction to Mammalian Genome Special Issue: Genome Editing., Lydia Teboul, Yann Hérault, Cynthia Smith, and Bruce Whitelaw
Investigating the effects of sodium channel dysfunction on chemotherapy induced peripheral neuropathy., Carla Martinez
Investigation of the effect of structural variants on RNA secondary structure., Amber Salome
Iron addiction: a novel therapeutic target in ovarian cancer., D Basuli, L Tesfay, Z Deng, B Paul, Y Yamamoto, Gang Ning, W Xian, F McKeon, M Lynch, C P Crum, P Hegde, M Brewer, X Wang, L D Miller, N Dyment, F M Torti, and S V Torti
Isolation and 3D expansion of multipotent Sox9+ mouse lung progenitors., Massimo Nichane, Asif Javed, V Sivakamasundari, Monisha Ganesan, Lay Teng Ang, Petra Kraus, Thomas Lufkin, Kyle M Loh, and Bing Lim
John Langworthy Fuller (1901-1992) Papers, The Jackson Laboratory
KLF6 depletion promotes NF-κB signaling in glioblastoma., A P Masilamani, R Ferrarese, E Kling, N K Thudi, Hoon Kim, D M Scholtens, F Dai, M Hadler, T Unterkircher, L Platania, A Weyerbrock, M Prinz, G Y Gillespie, G R Harsh Iv, M Bredel, and M S Carro
L1Base 2: more retrotransposition-active LINE-1s, more mammalian genomes., Tobias Penzkofer, Marten Jäger, Marek Figlerowicz, Richard Badge, Stefan Mundlos, Peter N Robinson, and Tomasz Zemojtel
Lethality in hspn mutant mice., Se Rin (Julie) Kim
Lithium reduces blood glucose levels, but aggravates albuminuria in BTBR-ob/ob mice., Theun de Groot, Lars Damen, Leanne Kosse, Mohammad Alsady, Rosalinda A. Doty, Ruben Baumgarten, Susan Sheehan, Johan van der Vlag, Ron Korstanje, and Peter M T Deen
Longevity as a complex genetic trait., George L. Sutphin and Ron Korstanje
Long-read ChIA-PET for base-pair-resolution mapping of haplotype-specific chromatin interactions., Xingwang Li, Oscar Junhong Luo, Ping Wang, Meizhen Zheng, Danjuan Wang, Emaly Piecuch, Jacqueline Jufen Zhu, Simon Zhongyuan Tian, Zhonghui Tang, Guoliang Li, and Yijun Ruan
Loss of FAS/FASL signalling does not reduce apoptosis in Sharpin null mice., Christopher S Potter, Kathleen A Silva, Victoria E. Kennedy, Timothy M Stearns, Harm HogenEsch, and John P Sundberg
Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross., John R Shorter, Fanny Odet, David L Aylor, Wenqi Pan, Chia-Yu Kao, Chen-Ping Fu, Andrew P Morgan, Seth Greenstein, Timothy A Bell, Alicia M Stevans, Ryan W Feathers, Sunny Patel, Sarah E Cates, Ginger D Shaw, Darla R Miller, Elissa J Chesler, Leonard McMillian, Deborah A O'Brien, and Fernando Pardo-Manuel de Villena
Manipulating beta cell regulatory circuitry using CRISPR/Cas9 epigenome editing., Rujia Lian
Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer., Jean M Winter, Derek E Gildea, Jonathan P Andreas, Daniel M. Gatti, Kendra A Williams, Minnkyong Lee, Ying Hu, Suiyuan Zhang, James C Mullikin, Tyra G Wolfsberg, Shannon K McDonnell, Zachary C Fogarty, Melissa C Larson, Amy J French, Daniel J Schaid, Stephen N Thibodeau, Gary A Churchill, and Nigel P S Crawford
Mean vector testing for high-dimensional dependent observations., Deepak Nag Ayyala, Junyong Park, and Anindya Roy
Mechanism of tandem duplication formation in BRCA1-mutant cells., Nicholas A Willis, Richard L Frock, Francesca Menghi, Erin E Duffey, Arvind Panday, Virginia Camacho, E Paul Hasty, Edison T Liu, Frederick W Alt, and Ralph Scully
Method of derivation and differentiation of mouse embryonic stem cells generating synchronous neuronal networks., Elena V Gazina, Emma Morrisroe, Gunarathna D C Mendis, Anna E Michalska, Joseph Chen, Christian M Nefzger, Benjamin N Rollo, Christopher A Reid, Martin Pera, and Steven Petrou
Microdose-Induced Drug-DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice., Maike Zimmermann, Si-Si Wang, Hongyong Zhang, Tzu-Yin Lin, Michael Malfatti, Kurt Haack, Ted Ognibene, Hongyuan Yang, Susan Airhart, Kenneth W Turteltaub, George D Cimino, Clifford G Tepper, Alexandra Drakaki, Karim Chamie, Ralph de Vere White, Chong-Xian Pan, and Paul T Henderson
MicroRNAs miR-203-3p, miR-664-3p and miR-708-5p are associated with median strain lifespan in mice., Benjamin P Lee, Ivana Burić, Anupriya George-Pandeth, Kevin Flurkey, David E Harrison, Rong Yuan, Luanne L. Peters, George A Kuchel, David Melzer, and Lorna W Harries
Migratory CD11b+ conventional dendritic cells induce T follicular helper cell-dependent antibody responses., Jayendra Kumar Krishnaswamy, Uthaman Gowthaman, Biyan Zhang, Johan Mattsson, Louis Szeponik, Dong Liu, Renee Wu, Theresa White, Samuele Calabro, Lan Xu, Magalie A Collet, Marina Yurieva, Samuel Alsén, Per Fogelstrand, Anne Walter, William R Heath, Scott N Mueller, Ulf Yrlid, Adam Williams, and Stephanie C Eisenbarth
Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea., Robert M Bowers, Nikos C Kyrpides, Ramunas Stepanauskas, Miranda Harmon-Smith, Devin Doud, T B K Reddy, Frederik Schulz, Jessica Jarett, Adam R Rivers, Emiley A Eloe-Fadrosh, Susannah G Tringe, Natalia N Ivanova, Alex Copeland, Alicia Clum, Eric D Becraft, Rex R Malmstrom, Bruce Birren, Mircea Podar, Peer Bork, George M. Weinstock, George M Garrity, Jeremy A Dodsworth, Shibu Yooseph, Granger Sutton, Frank O Glöckner, Jack A Gilbert, William C Nelson, Steven J Hallam, Sean P Jungbluth, Thijs J G Ettema, Scott Tighe, Konstantinos T Konstantinidis, Wen-Tso Liu, Brett J Baker, Thomas Rattei, Jonathan A Eisen, Brian Hedlund, Katherine D McMahon, Noah Fierer, Rob Knight, Rob Finn, Guy Cochrane, Ilene Karsch-Mizrachi, Gene W Tyson, Christian Rinke, Alla Lapidus, Folker Meyer, Pelin Yilmaz, Donovan H Parks, A M Eren, Lynn Schriml, Jillian F Banfield, Philip Hugenholtz, and Tanja Woyke
Modeling of Patient-Derived Xenografts in Colorectal Cancer., Anastasia Katsiampoura, Kanwal Raghav, Zhi-Qin Jiang, David G Menter, Andreas Varkaris, Maria P Morelli, Shanequa Manuel, Ji Wu, Alexey V Sorokin, Bahar Salimian Rizi, Christopher Bristow, Feng Tian, Susan Airhart, Mingshan Cheng, Bradley M Broom, Jeffrey Morris, Michael J Overman, Garth Powis, and Scott Kopetz
Modeling the response of a tumor-suppressive network to mitogenic and oncogenic signals., Xinyu Tian, Bo Huang, Xiao-Peng Zhang, Mingyang Lu, Feng Liu, José N Onuchic, and Wei Wang
Modulation of the adaptive immune system by cardiac fibroblasts., Maddie Mara
Molecular features of influenza A (H1N1)pdm09 prevalent in Mexico during winter seasons 2012-2014., Rocío Arellano-Llamas, Luis Alfaro-Ruiz, Cristian Arriaga Canon, Ivan Imaz Rosshandler, Alfredo Cruz-Lagunas, Joaquín Zúñiga, Rosa Rebollar Vega, Christopher W Wong, Sebastian Maurer-Stroh, Sandra Romero Córdoba, Edison T Liu, Alfredo Hidalgo-Miranda, and Joel A Vázquez-Pérez
Mouse Genome Database (MGD)-2017: community knowledge resource for the laboratory mouse., Judith A. Blake, Janan T. Eppig, James A. Kadin, Joel E Richardson, Cynthia Smith, Carol J Bult, and Mouse Genome Database Group
Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse., Janan T. Eppig
Mouse Models for Drug Discovery. Can New Tools and Technology Improve Translational Power?, Aamir Zuberi and Cathleen Lutz
Mouse models of human ocular disease for translational research., Mark P. Krebs, Gayle B. Collin, Wanda L. Hicks, Minzhong Yu, Jeremy R. Charette, Lan Ying Shi, Jieping Wang, Juergen K. Naggert, Neal S Peachey, and Patsy M. Nishina
mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors., Jungmin Lee, Brad Dykstra, Joel A Spencer, Laurie L Kenney, Dale L Greiner, Leonard D. Shultz, Michael A Brehm, Charles P Lin, Robert Sackstein, and Derrick J Rossi
mTOR Inhibitors in Castration-Resistant Prostate Cancer: A Systematic Review., Cara M. Statz, Sara E. Patterson, and Susan Mockus
Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy., Jana Blazkova, Sarthak Gupta, Yudong Liu, Brice Gaudilliere, Edward A Ganio, Christopher R Bolen, Ron Saar-Dover, Gabriela K Fragiadakis, Martin S Angst, Sarfaraz Hasni, Nima Aghaeepour, David Stevenson, Nicole Baldwin, Esperanza Anguiano, Damien Chaussabel, Matthew C Altman, Mariana J Kaplan, Mark M Davis, and David Furman
Multigene signature for predicting prognosis of patients with 1p19q co-deletion diffuse glioma., Xin Hu, Emmanuel Martinez-Ledesma, Siyuan Zheng, Hoon Kim, Floris P Barthel, Tao Jiang, Kenneth R Hess, and Roel G W Verhaak
Mutations in the Katnb1 gene cause left-right asymmetry and heart defects., Milena B Furtado, D Jo Merriner, Silke Berger, Danielle Rhodes, Duangporn Jamsai, and Moira K O'Bryan
Mutations in TP53, PIK3CA, PTEN and other genes in EGFR mutated lung cancers: Correlation with clinical outcomes., Paul A VanderLaan, Deepa Rangachari, Susan Mockus, Vanessa Spotlow, Honey V Reddi, Joan Malcolm, Mark S Huberman, Loren J Joseph, Susumu S Kobayashi, and Daniel B Costa
Naming CRISPR alleles: endonuclease-mediated mutation nomenclature across species., Michelle N Knowlton and Cynthia L Smith
Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity., F Bearoff, R Del Rio, L K Case, J A Dragon, T Nguyen-Vu, C-Y Lin, E P Blankenhorn, C Teuscher, and D N Krementsov
Navigating the Cancer Transcriptome by Decoding Divergent Oncogenic States., Samirkumar B Amin and Roel G W Verhaak
Neomorphic effects of the neonatal anemia (Nan-Eklf) mutation contribute to deficits throughout development., Antanas Planutis, Li Xue, Cecelia D Trainor, Mohan Dangeti, Kevin Gillinder, Miroslawa Siatecka, Danitza Nébor, Luanne L. Peters, Andrew C Perkins, and James J Bieker
Nervous system., Jessica M. Snyder, Catherine E. Hagan, Brad Bolon, and C Dirk Keene
Neuroinflammation in glaucoma: A new opportunity., Pete A. Williams, Nick Marsh-Armstrong, and Gareth R Howell
Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob., Lisa K Denzin, Aly A Khan, Francesca Virdis, Jessica Wilks, Melissa Kane, Helen A Beilinson, Stanislav Dikiy, Laure K Case, Derry C. Roopenian, Michele Witkowski, Alexander V Chervonsky, and Tatyana V Golovkina
NIA Interventions testing program: A Collaborative approach for investigating interventions to promote healthy aging., Nancy L. Nadon, Richard A. Miller, Randy Strong, and David E Harrison
NIA Interventions Testing Program: Investigating Putative Aging Intervention Agents in a Genetically Heterogeneous Mouse Model., Nancy L Nadon, Randy Strong, Richard A Miller, and David E Harrison
Nicotinamide and WLD(S) Act Together to Prevent Neurodegeneration in Glaucoma., Pete A. Williams, Jeffrey M. Harder, Nicole E Foxworth, Brynn H Cardozo, Kelly E Cochran, and Simon W M John
NMDA Receptors Regulate the Development of Neuronal Intrinsic Excitability through Cell-Autonomous Mechanisms., Guoqiang Hou and Zhong-Wei Zhang
Normal behavioral responses to light and darkness and the pupillary light reflex are dependent upon the olivary pretectal nucleus in the diurnal Nile grass rat., Andrew J Gall, Ohanes S Khacherian, Brandi Ledbetter, Sean P Deats, Megan Luck, Laura Smale, Lily Yan, and Antonio A Nunez
Of mice and CRISPR: The post-CRISPR future of the mouse as a model system for the human condition., Edison T Liu, Ewelina Bolcun-Filas, David S Grass, Cathleen Lutz, Stephen A Murray, Leonard D. Shultz, and Nadia Rosenthal
Once doesn't count: Phenotype-driven gene hunting in cohorts., Peter N Robinson
Open chromatin profiling as a novel strategy for identifying cancer cell of origin., Kira Young and Jennifer J. Trowbridge
Optimization and Control of Agent-Based Models in Biology: A Perspective., G An, B G Fitzpatrick, S Christley, P Federico, A Kanarek, R Miller Neilan, M Oremland, R Salinas, Reinhard Laubenbacher, and S Lenhart
Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways., Yoriko Saito, Yoshiki Mochizuki, Ikuko Ogahara, Takashi Watanabe, Leah Hogdal, Shinsuke Takagi, Kaori Sato, Akiko Kaneko, Hiroshi Kajita, Naoyuki Uchida, Takehiro Fukami, Leonard D. Shultz, Shuichi Taniguchi, Osamu Ohara, Anthony G Letai, and Fumihiko Ishikawa
PAF promotes stemness and radioresistance of glioma stem cells., Derrick Sek Tong Ong, Baoli Hu, Yan Wing Ho, Charles-Etienne Gabriel Sauvé, Christopher A Bristow, Qianghu Wang, Asha S Multani, Peiwen Chen, Luigi Nezi, Shan Jiang, Claire Elizabeth Gorman, Marta Moreno Monasterio, Dimpy Koul, Matteo Marchesini, Simona Colla, Eun-Jung Jin, Erik P Sulman, Denise J Spring, Wai-Kwan Alfred Yung, Roel G W Verhaak, Lynda Chin, Y Alan Wang, and Ronald A DePinho
Patient-derived xenograft (PDX) models in basic and translational breast cancer research., Lacey E Dobrolecki, Susan D Airhart, Denis G Alferez, Samuel Aparicio, Fariba Behbod, Mohamed Bentires-Alj, Cathrin Brisken, Carol J Bult, Shirong Cai, Robert B Clarke, Heidi Dowst, Matthew J Ellis, Eva Gonzalez-Suarez, Richard D Iggo, Peter Kabos, Shunqiang Li, Geoffrey J Lindeman, Elisabetta Marangoni, Aaron McCoy, Funda Meric-Bernstam, Helen Piwnica-Worms, Marie-France Poupon, Jorge Reis-Filho, Carol A Sartorius, Valentina Scabia, George Sflomos, Yizheng Tu, François Vaillant, Jane E Visvader, Alana Welm, Max S Wicha, and Michael T Lewis
PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models., Terrence F Meehan, Nathalie Conte, Theodore Goldstein, Giorgio Inghirami, Mark A Murakami, Sebastian Brabetz, Zhiping Gu, Jeffrey A Wiser, Patrick Dunn, Dale A. Begley, Debra M. Krupke, Andrea Bertotti, Alejandra Bruna, Matthew H Brush, Annette T Byrne, Carlos Caldas, Amanda L Christie, Dominic A Clark, Heidi Dowst, Jonathan R Dry, James H Doroshow, Olivier Duchamp, Yvonne A Evrard, Stephane Ferretti, Kristopher K Frese, Neal C Goodwin, Danielle Greenawalt, Melissa A Haendel, Els Hermans, Peter J Houghton, Jos Jonkers, Kristel Kemper, Tin O Khor, Michael T Lewis, K C Kent Lloyd, Jeremy Mason, Enzo Medico, Steven B Neuhauser, James M Olson, Daniel S Peeper, Oscar M Rueda, Je Kyung Seong, Livio Trusolino, Emilie Vinolo, Robert J Wechsler-Reya, David M Weinstock, Alana Welm, S John Weroha, Frédéric Amant, Stefan M Pfister, Marcel Kool, Helen Parkinson, Atul J Butte, and Carol J Bult
Pharmacological Inhibition of the DNA Damage Checkpoint Prevents Radiation-Induced Oocyte Death., Vera D Rinaldi, Kristin Hsieh, Robert Munroe, Ewelina Bolcun-Filas, and John C Schimenti
Phenotyping first-generation genome editing mutants: a new standard?, Lydia Teboul, Stephen A. Murray, and Patrick M Nolan
Plasma PPi Deficiency Is the Major, but Not the Exclusive, Cause of Ectopic Mineralization in an Abcc6(-/-) Mouse Model of PXE., Jingyi Zhao, Joshua Kingman, John P Sundberg, Jouni Uitto, and Qiaoli Li
Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling., Milena B Furtado, Julia C Wilmanns, Anjana Chandran, Joelle Perera, Olivia Hon, Christine Biben, Taylor J Willow, Hieu T Nim, Gurpreet Kaur, Stephanie Simonds, Qizhu Wu, David Willians, Ekaterina Salimova, Nicolas Plachta, James M. Denegre, Stephen A. Murray, Diane Fatkin, Michael Cowley, James T Pearson, David Kaye, Mirana Ramialison, Richard P Harvey, Nadia A Rosenthal, and Mauro W Costa
Polygenic and Mendelian mechanisms of inherited anemia., Tejal Patwardhan
Positional cloning of the genetic mutation and histological analysis of femoral nerve axonal degeneration in the NM4803 mouse mutant., Allen Schroeder
PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis., Emil D Parvanov, Hui Tian, Timothy Billings, Ruth L. Saxl, Catrina Spruce, Rakesh Aithal, Lumir Krejci, Kenneth Paigen, and Petko M. Petkov
Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma., Narendra Bharathy, Matthew N Svalina, Teagan P Settelmeyer, Megan M Cleary, Noah E Berlow, Susan D Airhart, Sunny Xiang, James Keck, James B Hayden, Jack F Shern, Atiya Mansoor, Melvin Lathara, Ganapati Srinivasa, David M Langenau, and Charles Keller
Precocious Interleukin 21 Expression in Naive Mice Identifies a Natural Helper Cell Population in Autoimmune Disease., Elisabeth A Marnik, Xulong Wang, Thomas J. Sproule, Giljun Park, Gregory J. Christianson, Sarah Kate Lane-Reticker, Shweta Jain, Ted Duffy, Hongsheng Wang, Gregory W. Carter, Herbert C Morse, and Derry C. Roopenian
Predicting differential regulation of cell cycle genes in aging hematopoietic progenitor cells., Zollie Yavarow
Prediction of Human Phenotype Ontology terms by means of hierarchical ensemble methods., Marco Notaro, Max Schubach, Peter N Robinson, and Giorgio Valentini
Prevalence of sexual dimorphism in mammalian phenotypic traits., Natasha A Karp, Jeremy Mason, Arthur L Beaudet, Yoav Benjamini, Lynette Bower, Robert E Braun, Steve D M Brown, Elissa J Chesler, Mary E Dickinson, Ann M Flenniken, Helmut Fuchs, Martin Hrabe de Angelis, Xiang Gao, Shiying Guo, Simon Greenaway, Ruth Heller, Yann Herault, Monica J Justice, Natalja Kurbatova, Christopher J Lelliott, K C Kent Lloyd, Ann-Marie Mallon, Judith E Mank, Hiroshi Masuya, Colin McKerlie, Terrence F Meehan, Richard F Mott, Stephen A. Murray, Helen Parkinson, Ramiro Ramirez-Solis, Luis Santos, John R Seavitt, Damian Smedley, Tania Sorg, Anneliese O Speak, Karen P Steel, Karen L. Svenson, Shigeharu Wakana, David West, Sara Wells, Henrik Westerberg, Shay Yaacoby, and Jacqueline K White
PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer., Jessie Hao-Ru Hsu, Benjamin Hubbell-Engler, Guillaume Adelmant, Jialiang Huang, Cailin E Joyce, Francisca Vazquez, Barbara A Weir, Philip Montgomery, Aviad Tsherniak, Andrew O Giacomelli, Jennifer A Perry, Jennifer J. Trowbridge, Yuko Fujiwara, Glenn S Cowley, Huafeng Xie, Woojin Kim, Carl D Novina, William C Hahn, Jarrod A Marto, and Stuart H Orkin
Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability., Kevin R Gillinder, Melissa D Ilsley, Danitza Nébor, Ravi Sachidanandam, Mathieu Lajoie, Graham W Magor, Michael R Tallack, Timothy Bailey, Michael J Landsberg, Joel P Mackay, Michael W Parker, Luke A Miles, Joel H. Graber, Luanne L. Peters, James J Bieker, and Andrew C Perkins
Properties and Immune Function of Cardiac Fibroblasts., Milena B Furtado and Muneer G. Hasham
Protein Ontology (PRO): enhancing and scaling up the representation of protein entities., Darren A Natale, Cecilia N Arighi, Judith A. Blake, Jonathan Bona, Chuming Chen, Sheng-Chih Chen, Karen R. Christie, Julie Cowart, Peter D'Eustachio, Alexander D Diehl, Harold J. Drabkin, William D Duncan, Hongzhan Huang, Jia Ren, Karen Ross, Alan Ruttenberg, Veronica Shamovsky, Barry Smith, Qinghua Wang, Jian Zhang, Abdelrahman El-Sayed, and Cathy H Wu
QTL and systems genetics analysis of mouse grooming and behavioral responses to novelty in an open field., A Delprato, M-P Algéo, B Bonheur, Jason A. Bubier, L Lu, R W Williams, Elissa J Chesler, and W E Crusio
Rapid replacement by non-vaccine pneumococcal serotypes may mitigate the impact of the pneumococcal conjugate vaccine on nasopharyngeal bacterial ecology., Brenda Kwambana-Adams, Blake M Hanson, Archibald Worwui, Schadrac Agbla, Ebenezer Foster-Nyarko, Fatima Ceesay, Chinelo Ebruke, Uzochukwu Egere, Yanjiao Zhou, Maze Ndukum, Erica Sodergren Weinstock, Michael Barer, Richard Adegbola, George M. Weinstock, and Martin Antonio
Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection., Benjamin Y Winer, Tiffany Huang, Benjamin E. Low, Cindy Avery, Mihai-Alexandru Pais, Gabriela Hrebikova, Evelyn Siu, Luis Chiriboga, Michael V. Wiles, and Alexander Ploss
Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors., Huipeng Li, Elise T Courtois, Debarka Sengupta, Yuliana Tan, Kok Hao Chen, Jolene Jie Lin Goh, Say Li Kong, Clarinda Chua, Lim Kiat Hon, Wah Siew Tan, Mark Wong, Paul Jongjoon Choi, Lawrence J K Wee, Axel M Hillmer, Iain Beehuat Tan, Paul Robson, and Shyam Prabhakar
Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells., Jung-Hyun Kim, Andreas Kurtz, Bao-Zhu Yuan, Fanyi Zeng, Geoff Lomax, Jeanne F Loring, Jeremy Crook, Ji Hyeon Ju, Laura Clarke, Maneesha S Inamdar, Martin Pera, Meri T Firpo, Michael Sheldon, Nafees Rahman, Orla O'Shea, Patricia Pranke, Qi Zhou, Rosario Isasi, Ruttachuk Rungsiwiwut, Shin Kawamata, Steve Oh, Tenneille Ludwig, Tohru Masui, Thomas J Novak, Tsuneo Takahashi, Wataru Fujibuchi, Soo Kyung Koo, and Glyn N Stacey
Report of the National Heart, Lung, and Blood Institute Working Group on Sex Differences Research in Cardiovascular Disease: Scientific Questions and Challenges., Christine Maric-Bilkan, Arthur P Arnold, Doris A Taylor, Melinda Dwinell, Susan E Howlett, Nanette Wenger, Jane F Reckelhoff, Kathryn Sandberg, Gary Churchill, Ellis Levin, and Martha S Lundberg
Reproducibility of histopathological findings in experimental pathology of the mouse: a sorry tail., Jerrold M Ward, Paul N Schofield, and John P Sundberg
Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis., Kerstin Seidel, Pauline Marangoni, Cynthia Tang, Bahar Houshmand, Wen Du, Richard L Maas, Stephen A Murray, Michael C Oldham, and Ophir D Klein
Respiratory manifestations in 38 patients with Alström syndrome., Caroline Boerwinkle, Jan D Marshall, Joy Bryant, William A Gahl, Kenneth N Olivier, and Meral Gunay-Aygun
Review of CO₂ as a Euthanasia Agent for Laboratory Rats and Mice., Gregory P Boivin, Debra L Hickman, Michelle A Creamer-Hente, Kathleen R Pritchett-Corning, and Natalie A Bratcher
Revisiting the Warnock rule., J Benjamin Hurlbut, Insoo Hyun, Aaron D Levine, Robin Lovell-Badge, Jeantine E Lunshof, Kirstin R W Matthews, Peter Mills, Alison Murdoch, Martin Pera, Christopher Thomas Scott, Juliet Tizzard, Mary Warnock, Magdalena Zernicka-Goetz, Qi Zhou, and Laurie Zoloth
S100A4 Is a Biomarker and Regulator of Glioma Stem Cells That Is Critical for Mesenchymal Transition in Glioblastoma., Kin-Hoe Chow, Hee Jung Park, Joshy George, Keiko Yamamoto, Andrew D Gallup, Joel H. Graber, Yuanxin Chen, Wen Jiang, Dennis A Steindler, Eric G Neilson, Betty Y S Kim, and Kyuson Yun
Severity of Demyelinating and Axonal Neuropathy Mouse Models Is Modified by Genes Affecting Structure and Function of Peripheral Nodes., Kathryn H. Morelli, Kevin L. Seburn, David G. Schroeder, Emily L Spaulding, Louise A. Dionne, Gregory A. Cox, and Robert W. Burgess
SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland., Emilia Peuhu, Riina Kaukonen, Martina Lerche, Markku Saari, Camilo Guzmán, Pia Rantakari, Nicola De Franceschi, Anni Wärri, Maria Georgiadou, Guillaume Jacquemet, Elina Mattila, Reetta Virtakoivu, Yuming Liu, Youmna Attieh, Kathleen A Silva, Timo Betz, John P Sundberg, Marko Salmi, Marie-Ange Deugnier, Kevin W Eliceiri, and Johanna Ivaska
Shedding light on microbial dark matter: reference-based species identification in microbiomes., Nicole Gay
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes., Nathan Lawlor, Joshy George, Mohan Bolisetty, Romy Kursawe, Lili Sun, V Sivakamasundari, Ina Kycia, Paul Robson, and Michael L. Stitzel
Skin and adnexa., John P Sundberg, Carmen J. Booth, Lillian B. Nanney, Philip Fleckman, and Lloyd E. King Jr
Skin fragility in the wild-derived, inbred mouse strain Mus pahari/EiJ., C Herbert Pratt, Christopher S Potter, Raoul V Kuiper, Son Yong Karst, Soheil S Dadras, Derry C. Roopenian, and John P Sundberg
Small-world networks exhibit pronounced intermittent synchronization., Anshul Choudhary, Chiranjit Mitra, Vivek Kohar, Sudeshna Sinha, and Jürgen Kurths
SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes., Grace Hwang, Fengyun Sun, Marilyn J. O'Brien, John J. Eppig, Mary Ann Handel, and Philip W Jordan
Spectral-domain optical coherence tomography findings in Alström syndrome., Gad Dotan, Vikas Khetan, Jan D Marshall, Elizabeth Affel, Denise Armiger-George, Juergen K. Naggert, Gayle B. Collin, and Alex V Levin
STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus., Peng Li, Suman Mitra, Rosanne Spolski, Jangsuk Oh, Wei Liao, Zhonghui Tang, Fei Mo, Xingwang Li, Erin E West, Daniel Gromer, Jian-Xin Lin, Chengyu Liu, Yijun Ruan, and Warren J Leonard
Structural Variation Shapes the Landscape of Recombination in Mouse., Andrew P Morgan, Daniel M. Gatti, Maya L Najarian, Thomas M Keane, Raymond J Galante, Allan I Pack, Richard Mott, Gary A. Churchill, and Fernando Pardo-Manuel de Villena
Survey on variation in epigenetic histone modification across nine inbred mouse strains., Arya Royal
Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency., Florie Borel, Qiushi Tang, Gwladys Gernoux, Cynthia Greer, Ziqiong Wang, Adi Barzel, Mark A Kay, Leonard D. Shultz, Dale L Greiner, Terence R Flotte, Michael A Brehm, and Christian Mueller
Survival of Del17p CLL Depends on Genomic Complexity and Somatic Mutation., Lijian Yu, Haesook T Kim, Siddha N Kasar, Parul Benien, Wei Du, Kevin Hoang, Andrew Aw, Bethany Tesar, Reina Improgo, Stacey M Fernandes, Saranya Radhakrishnan, Josephine L Klitgaard, Charles Lee, Gad Getz, Sunita R Setlur, and Jennifer R Brown
SVEP1 plays a crucial role in epidermal differentiation., Liat Samuelov, Qiaoli Li, Ron Bochner, Nicole A Najor, Lauren Albrecht, Natalia Malchin, Tomer Goldsmith, Meital Grafi-Cohen, Dan Vodo, Gilad Fainberg, Benjamin Meilik, Ilan Goldberg, Emily Warshauer, Tova Rogers, Sarah Edie, Akemi Ishida-Yamamoto, Lisa M. Burzenski, Noam Erez, Stephen A Murray, Alan D Irvine, Leonard D. Shultz, Kathleen J Green, Jouni Uitto, Eli Sprecher, and Ofer Sarig
Systematic analysis of telomere length and somatic alterations in 31 cancer types., Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang, Tara Lichtenberg, Jian Hu, Jianhua Zhang, Siyuan Zheng, and Roel G W Verhaak
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program., John P Sundberg, Soheil S Dadras, Kathleen A Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N Schofield, and C Herbert Pratt
Systemic autoimmunity induced by the TLR7/8 agonist Resiquimod causes myocarditis and dilated cardiomyopathy in a new mouse model of autoimmune heart disease., Muneer G. Hasham, Nicoleta Baxan, Daniel J Stuckey, Jane Branca, Bryant Perkins, Oliver Dent, Ted Duffy, Tolani S Hameed, Sarah E Stella, Mohammed Bellahcene, Michael D Schneider, Sian E Harding, Nadia Rosenthal, and Susanne Sattler
Systems Genetic Analysis in GeneNetwork.org., Clarissa C Parker, Price E. Dickson, Vivek M. Philip, Mary Thomas, and Elissa J Chesler
Tandem duplications affect gene integrity/expression in triple negative breast cancer., Tyler Jackson
Targeting interferon-alpha to dendritic cells enhances a CD8(+) T cell response to a human CD40-targeted cancer vaccine., John P Graham, Pierre Authie, A Karolina Palucka, and Gerard Zurawski
Testicular adenosine to inosine RNA editing in the mouse is mediated by ADARB1†,‡., Elizabeth M Snyder, Konstantin Licht, and Robert E Braun
Testing the paradigm: cancer gene sets and the hallmarks of cancer., Jesus Roberto Franco
The chromatin accessibility signature of human immune aging stems from CD8(+) T cells., Duygu Ucar, Eladio J Marquez, Cheng-Han Chung, Radu Marches, Robert J Rossi, Asli Uyar, Te-Chia Wu, Joshy George, Michael L. Stitzel, A Karolina Palucka, George A Kuchel, and Jacques Banchereau
The complex genetics of hypoplastic left heart syndrome., Xiaoqin Liu, Hisato Yagi, Shazina Saeed, Abha S Bais, George C Gabriel, Zhaohan Chen, Kevin A Peterson, You Li, Molly C Schwartz, William T Reynolds, Manush Saydmohammed, Brian Gibbs, Yijen Wu, William Devine, Bishwanath Chatterjee, Nikolai T Klena, Dennis Kostka, Karen L de Mesy Bentley, Madhavi K Ganapathiraju, Phillip Dexheimer, Linda Leatherbury, Omar Khalifa, Anchit Bhagat, Maliha Zahid, William Pu, Simon Watkins, Paul Grossfeld, Stephen A. Murray, George A Porter, Michael Tsang, Lisa J Martin, D Woodrow Benson, Bruce J Aronow, and Cecilia W Lo
The Degeneration and Apoptosis Patterns of Cone Photoreceptors in rd11 Mice., Hua Zhang, Xia Li, Xufeng Dai, Juanjuan Han, Yangyang Zhang, Yan Qi, Ying He, Yan Liu, Bo Chang, and Ji-Jing Pang
The DNA Damage Checkpoint Eliminates Mouse Oocytes with Chromosome Synapsis Failure., Vera D Rinaldi, Ewelina Bolcun-Filas, Hiroshi Kogo, Hiroki Kurahashi, and John C Schimenti
The effects of high-fat diets with varied carbohydrate content on the development of diabetes in obese mouse models., Emma Anderson
The experimental validation of structural variation candidates produced by the FusorSV algorithm., John E. Sargent
The Gene Ontology of eukaryotic cilia and flagella., Paola Roncaglia, Teunis J P van Dam, Karen R. Christie, Lora Nacheva, Grischa Toedt, Martijn A Huynen, Rachael P Huntley, Toby J Gibson, and Jane Lomax
The Human Phenotype Ontology in 2017., Sebastian Köhler, Nicole A Vasilevsky, Mark Engelstad, Erin Foster, Julie McMurry, Ségolène Aymé, Gareth Baynam, Susan M. Bello, Cornelius F Boerkoel, Kym M Boycott, Michael Brudno, Orion J Buske, Patrick F Chinnery, Valentina Cipriani, Laureen E Connell, Hugh J S Dawkins, Laura E DeMare, Andrew D Devereau, Bert B A de Vries, Helen V Firth, Kathleen Freson, Daniel Greene, Ada Hamosh, Ingo Helbig, Courtney Hum, Johanna A Jähn, Roger James, Roland Krause, Stanley J F Laulederkind, Hanns Lochmüller, Gholson J Lyon, Soichi Ogishima, Annie Olry, Willem H Ouwehand, Nikolas Pontikos, Ana Rath, Franz Schaefer, Richard H Scott, Michael Segal, Panagiotis I Sergouniotis, Richard Sever, Cynthia L Smith, Volker Straub, Rachel Thompson, Catherine Turner, Ernest Turro, Marijcke W M Veltman, Tom Vulliamy, Jing Yu, Julie von Ziegenweidt, Andreas Zankl, Stephan Züchner, Tomasz Zemojtel, Julius O B Jacobsen, Tudor Groza, Damian Smedley, Christopher J Mungall, Melissa Haendel, and Peter N Robinson
The influence of canalization on the robustness of Boolean networks, C Kadelka, J Kuipers, and Reinhard Laubenbacher
The LGN protein promotes planar proliferative divisions in the neocortex but apicobasal asymmetric terminal divisions in the retina., Marine Lacomme, Basile Tarchini, Camille Boudreau-Pinsonneault, Carine Monat, and Michel Cayouette
The Monarch Initiative: an integrative data and analytic platform connecting phenotypes to genotypes across species., Christopher J Mungall, Julie A McMurry, Sebastian Köhler, James P Balhoff, Charles Borromeo, Matthew Brush, Seth Carbon, Tom Conlin, Nathan Dunn, Mark Engelstad, Erin Foster, J P Gourdine, Julius O B Jacobsen, Dan Keith, Bryan Laraway, Suzanna E Lewis, Jeremy NguyenXuan, Kent Shefchek, Nicole Vasilevsky, Zhou Yuan, Nicole Washington, Harry Hochheiser, Tudor Groza, Damian Smedley, Peter N Robinson, and Melissa A Haendel
The mouse Gene Expression Database (GXD): 2017 update., Jacqueline H. Finger, Constance M. Smith, Terry F. Hayamizu, Ingeborg J. McCright, Jingxia Xu, MeiYee Law, David R. Shaw, Richard M. Baldarelli, Jon S Beal, Olin Blodgett, Jeff W Campbell, Lori E. Corbani, Jill R Lewis, Kim L. Forthofer, Pete J. Frost, Sharon C Giannatto, Lucie Hutchins, Dave Miers, Howie Motenko, Kevin R. Stone, Janan T. Eppig, James A. Kadin, Joel E Richardson, and Martin Ringwald
The Mouse Tumor Biology Database: A Comprehensive Resource for Mouse Models of Human Cancer., Debra M. Krupke, Dale A. Begley, John P Sundberg, Joel E Richardson, Steven B Neuhauser, and Carol J Bult
The Phosphatidylinositol 3-Kinase Pathway as a Potential Therapeutic Target in Bladder Cancer., Shu-Xiong Zeng, Yanjun Zhu, Ai-Hong Ma, Weimin Yu, Hongyong Zhang, Tzu-Yin Lin, Wei Shi, Clifford G Tepper, Paul T Henderson, Susan Airhart, Jian-Ming Guo, Chuan-Liang Xu, Ralph W deVere White, and Chong-Xian Pan
The relationship between the adaptive immune system and aging., Samuel Elliot Krause
The role of androgen receptor in meiotic progress of male germ cells., Nadia V. Harerimana
The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation., Daosheng Huang, Guoji Guo, Ping Yuan, Amy Ralston, Lingang Sun, Mikael Huss, Tapan Mistri, Luca Pinello, Huck Hui Ng, Guocheng Yuan, Junfeng Ji, Janet Rossant, Paul Robson, and Xiaoping Han
The role of platelet and endothelial GARP in thrombosis and hemostasis., Elien Vermeersch, Frederik Denorme, Wim Maes, Simon F De Meyer, Karen Vanhoorelbeke, Justin Edwards, Ethan M Shevach, Derya Unutmaz, Hodaka Fujii, Hans Deckmyn, and Claudia Tersteeg
The rs7903146 Variant in the TCF7L2 Gene Increases the Risk of Prediabetes/Type 2 Diabetes in Obese Adolescents by Impairing β-Cell Function and Hepatic Insulin Sensitivity., Catrina Cropano, Nicola Santoro, Leif Groop, Chiara Dalla Man, Claudio Cobelli, Alfonso Galderisi, Romy Kursawe, Bridget Pierpont, Martina Goffredo, and Sonia Caprio
The Spindle Orientation Machinery Beyond Mitosis: When Cell Specialization Demands Polarization., Abigail L.D. Tadenev and Basile Tarchini
The Vital Role of Pathology in Improving Reproducibility and Translational Relevance of Aging Studies in Rodents., P M Treuting, J M Snyder, Y Ikeno, P N Schofield, J M Ward, and John P Sundberg
Time-Restricted Feeding Shifts the Skin Circadian Clock and Alters UVB-Induced DNA Damage., Hong Wang, Elyse van Spyk, Qiang Liu, Mikhail Geyfman, Michael L Salmans, Vivek Kumar, Alexander Ihler, Ning Li, Joseph S Takahashi, and Bogi Andersen
Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease., Vishnu Hosur, Bonnie L. Lyons, Lisa M. Burzenski, and Leonard D. Shultz
Towards a standard ontology metadata model., Hua Min, Stuart Turner, Sherri de Coronado, Brian Davis, Trish Whetzel, Robert R. Freimuth, Harold R. Solbrig, Richard Kiefer, Grace Stafford, Lawrence Wright, and Riki Ohira
Tracking spontaneous hair cell regeneration in wildtype mice., Michaela Flonard
Training at Bar Harbor., C C Little
Training mouse pathologists: 15 years of workshops on the pathology of mouse models of human disease., John P Sundberg, Kelli Boyd, Harm Hogenesch, Alexander Y Nikitin, Piper M Treuting, and Jerrold M Ward
Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy., Qiming Wang, Jeremy Racine, Jeremy Ratiu, Shu Wang, Rachel Ettinger, Clive Wasserfall, Mark A Atkinson, and David V. Serreze
Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations., James N Sleigh, John M Dawes, Steven J West, Na Wei, Emily L Spaulding, Adriana Gómez-Martín, Qian Zhang, Robert W. Burgess, M Zameel Cader, Kevin Talbot, Xiang-Lei Yang, David L Bennett, and Giampietro Schiavo
Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment., Qianghu Wang, Baoli Hu, Xin Hu, Hoon Kim, Massimo Squatrito, Lisa Scarpace, Ana C deCarvalho, Sali Lyu, Pengping Li, Yan Li, Floris P Barthel, Hee Jin Cho, Yu-Hsi Lin, Nikunj Satani, Emmanuel Martinez-Ledesma, Siyuan Zheng, Edward Chang, Charles-Etienne Gabriel Sauvé, Adriana Olar, Zheng D Lan, Gaetano Finocchiaro, Joanna J Phillips, Mitchel S Berger, Konrad R Gabrusiewicz, Guocan Wang, Eskil Eskilsson, Jian Hu, Tom Mikkelsen, Ronald A DePinho, Florian Muller, Amy B Heimberger, Erik P Sulman, Do-Hyun Nam, and Roel G W Verhaak
Tutorial on Protein Ontology Resources., Cecilia N Arighi, Harold J. Drabkin, Karen R. Christie, Karen E Ross, and Darren A Natale
Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures., Javad Noorbakhsh and Jeffrey H Chuang
Understanding Human Autoimmunity and Autoinflammation Through Transcriptomics., Romain Banchereau, Alma-Martina Cepika, Jacques Banchereau, and Virginia Pascual
Using Vascular Landmarks to Orient 3D Optical Coherence Tomography Images of the Mouse Eye., Mark P. Krebs
Validation of Metagenomic Next-Generation Sequencing Tests for Universal Pathogen Detection., Robert Schlaberg, Charles Y Chiu, Steve Miller, Gary W Procop, and George M. Weinstock
Variable patterns of ectopic mineralization in Enpp1asj-2J mice, a model for generalized arterial calcification of infancy., Sarah Y Siu, Nathaniel A Dyment, David W Rowe, John P Sundberg, Jouni Uitto, and Qiaoli Li
Varying non-synonymous/synonymous rate ratios (dN/dS) in TCGA data points to prevalence of Darwinian tumor evolution, Alexander Iyabor Jr.
Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice., Pete A. Williams, Jeffrey M. Harder, Nicole E Foxworth, Kelly E Cochran, Vivek M. Philip, Vittorio Porciatti, Oliver Smithies, and Simon W M John
What can the genomics of normal development tell us about disease?, Raphael B. Espinoza
Workshop on challenges, insights, and future directions for mouse and humanized models in cancer immunology and immunotherapy: a report from the associated programs of the 2016 annual meeting for the Society for Immunotherapy of cancer., Andrew Zloza, A Karolina Palucka, Lisa M Coussens, Philip J Gotwals, Mark B Headley, Elizabeth M Jaffee, Amanda W Lund, Arlene H Sharpe, Mario Sznol, Derek A Wainwright, Kwok-Kin Wong, and Marcus W Bosenberg