Content Posted in 2018
A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease., Xulong Wang, Vivek M. Philip, Guruprasad Ananda, Charles C White, Ankit Malhotra, Paul J Michalski, Krishna R Murthy Karuturi, Sumana R Chintalapudi, Casey Acklin, Michael Sasner, David A Bennett, Philip L De Jager, Gareth R Howell, and Gregory W. Carter
Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy., Zhongying Mo, Xiaobei Zhao, Huaqing Liu, Qinghua Hu, Xu-Qiao Chen, Jessica Pham, Na Wei, Ze Liu, Jiadong Zhou, Robert W. Burgess, Samuel L Pfaff, C Thomas Caskey, Chengbiao Wu, Ge Bai, and Xiang-Lei Yang
Acclimation and Institutionalization of the Mouse Microbiota Following Transportation., Dan R Montonye, Aaron C Ericsson, Susheel B Busi, Cathleen Lutz, Keegan Wardwell, and Craig L Franklin
A change of heart: a transforming view of cardiac function., Alexander R Pinto
A commensal strain of Staphylococcus epidermidis protects against skin neoplasia., Teruaki Nakatsuji, Tiffany H Chen, Anna M Butcher, Lynnie L Trzoss, Sang-Jip Nam, Karina T Shirakawa, Wei Zhou, Julia Oh, Michael Otto, William Fenical, and Richard L Gallo
A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression., Ina Kycia, Brooke N Wolford, Jeroen R Huyghe, Christian Fuchsberger, Swarooparani Vadlamudi, Romy Kursawe, Ryan P Welch, Ricardo d'Oliveira Albanus, Asli Uyar, Shubham Khetan, Nathan Lawlor, Mohan Bolisetty, Anubhuti Mathur, Johanna Kuusisto, Markku Laakso, Duygu Ucar, Karen L Mohlke, Michael Boehnke, Francis S Collins, Stephen C J Parker, and Michael L. Stitzel
Activation of Serine One-Carbon Metabolism by Calcineurin Aβ1 Reduces Myocardial Hypertrophy and Improves Ventricular Function., Laura Padrón-Barthe, María Villalba-Orero, Jesús M Gómez-Salinero, Rebeca Acín-Pérez, Sara Cogliati, Marina López-Olañeta, Paula Ortiz-Sánchez, Elena Bonzón-Kulichenko, Jesús Vázquez, Pablo García-Pavía, Nadia Rosenthal, José Antonio Enríquez, and Enrique Lara-Pezzi
ADAM17 is essential for ectodomain shedding of the EGF-receptor ligand amphiregulin., Vishnu Hosur, Michelle L Farley, Lisa M. Burzenski, Leonard D. Shultz, and Michael V. Wiles
A Database Study of Visual Outcomes and Intraoperative Complications of Postvitrectomy Cataract Surgery., Mohamed Kamel Soliman, Joshua S Hardin, Fayez Jawed, Sami H Uwaydat, Mohammed F Faramawi, Colin J Chu, Yit C Yang, and Ahmed B Sallam
Addressing current challenges in cancer immunotherapy with mathematical and computational modelling., Anna Konstorum, Anthony T Vella, Adam J Adler, and Reinhard Laubenbacher
ADIPOR1 is essential for vision and its RPE expression is lost in the Mfrp, Valentin M Sluch, Angela Banks, Hui Li, Maura A Crowley, Vanessa Davis, Chuanxi Xiang, Junzheng Yang, John T Demirs, Joanna Vrouvlianis, Barrett Leehy, Shawn Hanks, Alexandra M Hyman, Jorge Aranda, Bo Chang, Chad E Bigelow, and Dennis S Rice
A FRMD4B variant suppresses dysplastic photoreceptor lesions in models of enhanced S-cone syndrome and of Nrl deficiency., Yang Kong, Lihong Zhao, Jeremy R. Charette, Wanda L. Hicks, Lisa Stone, Patsy M. Nishina, and Juergen K. Naggert
A human endothelial cell-based recycling assay for screening of FcRn targeted molecules., Algirdas Grevys, Jeannette Nilsen, Kine M K Sand, Muluneh B Daba, Inger Øynebråten, Malin Bern, Martin B McAdam, Stian Foss, Tilman Schlothauer, Terje E Michaelsen, Gregory J. Christianson, Derry C. Roopenian, Richard S Blumberg, Inger Sandlie, and Jan Terje Andersen
A Hypermorphic Nfkbid Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in NOD Mice., Maximiliano Presa, Jeremy Racine, Jennifer R Dwyer, Deanna Lamont, Jeremy Ratiu, Vishal Kumar Sarsani, Yi-Guang Chen, Aron Geurts, Ingo Schmitz, Timothy M Stearns, Jennifer Allocco, Harry Chapman, and David V. Serreze
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction., Michael R Bowl, Michelle M Simon, Neil J Ingham, Simon Greenaway, Luis Santos, Heather Cater, Sarah Taylor, Jeremy Mason, Natalja Kurbatova, Selina Pearson, Lynette R Bower, Dave A Clary, Hamid Meziane, Patrick Reilly, Osamu Minowa, Lois Kelsey, International Mouse Phenotyping Consortium, Glauco P Tocchini-Valentini, Xiang Gao, Allan Bradley, William C Skarnes, Mark Moore, Arthur L Beaudet, Monica J Justice, John Seavitt, Mary E Dickinson, Wolfgang Wurst, Martin Hrabe de Angelis, Yann Herault, Shigeharu Wakana, Lauryl M J Nutter, Ann M Flenniken, Colin McKerlie, Stephen A. Murray, Karen L. Svenson, Robert E Braun, David B West, K C Kent Lloyd, David J Adams, Jacqui White, Natasha Karp, Paul Flicek, Damian Smedley, Terrence F Meehan, Helen E Parkinson, Lydia M Teboul, Sara Wells, Karen P Steel, Ann-Marie Mallon, and Steve D M Brown
Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates., Fang Li, Ruijuan Xu, Benjamin E. Low, Chih-Li Lin, Monica Garcia-Barros, Jennifer Schrandt, Izolda Mileva, Ashley Snider, Catherine K Luo, Xian-Cheng Jiang, Ming-Song Li, Yusuf A Hannun, Lina M Obeid, Michael V. Wiles, and Cungui Mao
Alström syndrome: Renal findings in correlation with obesity, insulin resistance, dyslipidemia and cardiomyopathy in 38 patients prospectively evaluated at the NIH clinical center., Meryl Waldman, Joan C Han, Daniela P Reyes-Capo, Joy Bryant, Kathryn A Carson, Baris Turkbey, Peter Choyke, Juergen K. Naggert, William A Gahl, Jan D Marshall, and Meral Gunay-Aygun
Alterations in the Rho pathway contribute to Epstein-Barr virus-induced lymphomagenesis in immunosuppressed environments., Sung-Yup Cho, Chang Ohk Sung, Jeesoo Chae, Jieun Lee, Deukchae Na, Wonyoung Kang, Jinjoo Kang, Seoyeon Min, Ahra Lee, Eunhye Kwak, Jooyoung Kim, Boram Choi, Hyunsoo Kim, Jeffrey H Chuang, Hyo-Kyung Pak, Chan-Sik Park, Sanghui Park, Young Hyeh Ko, Dakeun Lee, Jin Roh, Min-Sun Cho, Seongyeol Park, Young Seok Ju, Yun-Suhk Suh, Seong-Ho Kong, Hyuk-Joon Lee, James Keck, Jacques Banchereau, Edison T Liu, Woo-Ho Kim, Hansoo Park, Han-Kwang Yang, Jong-Il Kim, and Charles Lee
Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics., Laura M Urbanski, Nathan Leclair, and Olga Anczuków
Amelioration of Neurosensory Structure and Function in Animal and Cellular Models of a Congenital Blindness., Ji Yun Song, Puya Aravand, Sergei Nikonov, Lanfranco Leo, Arkady Lyubarsky, Jeannette L Bennicelli, Jieyan Pan, Zhangyong Wei, Ivan Shpylchak, Pamela Herrera, Daniel J Bennett, Nicoletta Commins, Albert M Maguire, Jennifer Pham, Anneke I den Hollander, Frans P M Cremers, Robert K Koenekoop, Ronald Roepman, Patsy M. Nishina, Shangzhen Zhou, Wei Pan, Gui-Shuang Ying, Tomas S Aleman, Jimmy de Melo, Ilan McNamara, Junwei Sun, Jason Mills, and Jean Bennett
A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci., Hélène Choquet, Seyyedhassan Paylakhi, Stephen C. Kneeland, Khanh K Thai, Thomas J Hoffmann, Jie Yin, Mark N Kvale, Yambazi Banda, Nicholas G Tolman, Pete A. Williams, Catherine Schaefer, Ronald B Melles, Neil Risch, Simon W M John, K Saidas Nair, and Eric Jorgenson
A multi-tissue full lifespan epigenetic clock for mice., Michael J Thompson, Karolina Chwiałkowska, Liudmilla Rubbi, Aldons J Lusis, Richard C Davis, Anuj Srivastava, Ron Korstanje, Gary A Churchill, Steve Horvath, and Matteo Pellegrini
An Analysis of the Epidemic of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Convergence of Two Evolutionary Mechanisms Creates the "Perfect Storm"., Laura J Rojas, George M. Weinstock, Elsa De La Cadena, Lorena Diaz, Rafael Rios, Blake M Hanson, Joseph S Brown, Purva Vats, Daniel S Phillips, Hoan Nguyen, Kristine M Hujer, Adriana Correa, Mark D Adams, Federico Perez, Erica Sodergren Weinstock, Apurva Narechania, Paul J Planet, Maria V Villegas, Robert A Bonomo, and Cesar A Arias
Androgen receptor deficiency in monocytes/macrophages does not alter adiposity or glucose homeostasis in male mice., Katya B Rubinow, Barbara Houston, Shari Wang, Leela Goodspeed, Kayoko Ogimoto, Gregory J Morton, Christopher McCarty, Robert E Braun, and Stephanie T Page
A neural network based model effectively predicts enhancers from clinical ATAC-seq samples., Asa Thibodeau, Asli Uyar, Shubham Khetan, Michael L. Stitzel, and Duygu Ucar
A new GARS mutation, S625L, sensitizes peripheral neurons to degeneration., Donson Cook-Gallardo
Animal models for evaluation of albumin-based therapeutics, Jeannette Nilsen, Inger Sandlie, Derry C. Roopenian, and Jan Terje Andersen
An important role for periplasmic storage in Pseudomonas aeruginosa copper homeostasis revealed by a combined experimental and computational modeling study., Jignesh H Parmar, Julia Quintana, David Ramírez, Reinhard Laubenbacher, José M Argüello, and Pedro Mendes
An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues., Christopher Terranova, Ming Tang, Elias Orouji, Mayinuer Maitituoheti, Ayush Raman, Samirkumar B Amin, Zhiyi Liu, and Kunal Rai
An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos., Wenqing Jean Lee, Sumantra Chatterjee, Sook Peng Yap, Siew Lan Lim, Xing Xing, Petra Kraus, Wenjie Sun, Xiaoming Hu, V Sivakamasundari, Hsiao Yun Chan, Prasanna R Kolatkar, Shyam Prabhakar, and Thomas Lufkin
ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase., My-Nuong Vo, Markus Terrey, Jeong Woong Lee, Bappaditya Roy, James J Moresco, Litao Sun, Hongjun Fu, Qi Liu, Thomas G Weber, John R Yates, Kurt Fredrick, Paul Schimmel, and Susan L Ackerman
Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions., Nicolas Floc'h, Matthew J Martin, Jonathan W Riess, Jonathan P Orme, Anna D Staniszewska, Ludovic Ménard, Maria Emanuela Cuomo, Daniel J O'Neill, Richard A Ward, M Raymond V Finlay, Darren McKerrecher, Mingshan Cheng, Daniel P Vang, Rebekah A Burich, James G. Keck, David R Gandara, Philip C Mack, and Darren A E Cross
A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes., Ahrim Youn, Kyung In Kim, Raul Rabadan, Benjamin Tycko, Yufeng Shen, and Shuang Wang
A Prospective Cohort Multicenter Study of Molecular Epidemiology and Phylogenomics of Staphylococcus aureus Bacteremia in Nine Latin American Countries., Cesar A Arias, Jinnethe Reyes, Lina Paola Carvajal, Sandra Rincon, Lorena Diaz, Diana Panesso, Gabriel Ibarra, Rafael Rios, Jose M Munita, Mauro J Salles, Carlos Alvarez-Moreno, Jaime Labarca, Coralith Garcia, Carlos M Luna, Carlos Mejia-Villatoro, Jeannete Zurita, Manuel Guzman-Blanco, Eduardo Rodriguez-Noriega, Apurva Narechania, Laura J Rojas, Paul J Planet, George M Weinstock, Eduardo Gotuzzo, and Carlos Seas
A prospective microbiome-wide association study of food sensitization and food allergy in early childhood., Jessica H Savage, Kathleen A Lee-Sarwar, Joanne Sordillo, Supinda Bunyavanich, Yanjiao Zhou, George O'Connor, Megan Sandel, Leonard B Bacharier, Robert Zeiger, Erica Sodergren Weinstock, George M. Weinstock, Diane R Gold, Scott T Weiss, and Augusto A Litonjua
A reporter system for template bias of meiotic repair in mammals., Emily Bramel
A robust Pax7EGFP mouse that enables the visualization of dynamic behaviors of muscle stem cells., Elisia D Tichy, David K Sidibe, Christopher D Greer, Nicholas M Oyster, Panteleimon Rompolas, Nadia Rosenthal, Helen M Blau, and Foteini Mourkioti
A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development., Basile Tarchini, Chantal M. Longo-Guess, Cong Tian, Abigail L.D. Tadenev, Nicholas Devanney, and Kenneth R. Johnson
Assessing Alzheimer's disease phenotypes in a type 2 diabetic mouse model., Bansri Patel
Assessing Healthspan and Lifespan Measures in Aging Mice: Optimization of Testing Protocols, Replicability, and Rater Reliability., Stacey J Sukoff Rizzo, Laura C. Anderson, Torrian L Green, Tracy C. McGarr, Gaylynn Wells, and Shawn S Winter
A Systems Biology Approach to Understanding the Pathophysiology of High-Grade Serous Ovarian Cancer: Focus on Iron and Fatty Acid Metabolism., Anna Konstorum, Miranda L Lynch, Suzy V Torti, Frank M Torti, and Reinhard C Laubenbacher
Automatic glomerular identification and quantification of histological phenotypes using image analysis and machine learning., Susan M Sheehan and Ron Korstanje
Biallelic mutations in FDXR cause neurodegeneration associated with inflammation., Jesse Slone, Yanyan Peng, Adam Chamberlin, Belinda S. Harris, Julie Kaylor, Marie T McDonald, Monica Lemmon, Mays Antonine El-Dairi, Dmitry Tchapyjnikov, Laura A Gonzalez-Krellwitz, Elizabeth A Sellars, Allyn McConkie-Rosell, Laura G Reinholdt, and Taosheng Huang
Biological explanations for discordant noninvasive prenatal test results: Preliminary data and lessons learned., Louise Wilkins-Haug, Chengsheng Zhang, Eliza Cerveira, Mallory Ryan, Adam Mil-Homens, Qihui Zhu, Honey V Reddi, Charles Lee, and Diana W Bianchi
Capturing Totipotent Stem Cells., Christopher L. Baker and Martin F Pera
Cardioprotective effects of dietary rapamycin on adult female C57BLKS/J-Lepr, Peter C. Reifsnyder, Sergey Ryzhov, Kevin Flurkey, Rea P Anunciado-Koza, Ian Mills, David E Harrison, and Robert A Koza
Cell Labeling with Magneto-Endosymbionts and the Dissection of the Subcellular Location, Fate, and Host Cell Interactions., Kayla R Lee, Abdul Wakeel, Papia Chakraborty, Chandler S Foote, Lauren Kajiura, Joyce C Barrozo, Andrea C Chan, Alexey V Bazarov, Ryan Spitler, Peter M Kutny, James M. Denegre, Robert A. Taft, Joachim Seemann, Bradley W Rice, Christopher H Contag, Brian K Rutt, and Caleb B Bell
Characterization of glycosylphosphatidylinositol biosynthesis defects by clinical features, flow cytometry, and automated image analysis., Alexej Knaus, Jean Tori Pantel, Manuela Pendziwiat, Nurulhuda Hajjir, Max Zhao, Tzung-Chien Hsieh, Max Schubach, Yaron Gurovich, Nicole Fleischer, Marten Jäger, Sebastian Köhler, Hiltrud Muhle, Christian Korff, Rikke S Møller, Allan Bayat, Patrick Calvas, Nicolas Chassaing, Hannah Warren, Steven Skinner, Raymond Louie, Christina Evers, Marc Bohn, Hans-Jürgen Christen, Myrthe van den Born, Ewa Obersztyn, Agnieszka Charzewska, Milda Endziniene, Fanny Kortüm, Natasha Brown, Peter N Robinson, Helenius J Schelhaas, Yvonne Weber, Ingo Helbig, Stefan Mundlos, Denise Horn, and Peter M Krawitz
Characterization of strain specific cardiac macrophage-trophic microenvironments., Kelsey Letson
Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy., Bruno Gomes, Gregory Driessens, Derek Bartlett, Danying Cai, Sandra Cauwenberghs, Stefano Crosignani, Deepak Dalvie, Sofie Denies, Christopher P Dillon, Valeria R Fantin, Jie Guo, Marie-Claire Letellier, Wenlin Li, Karen Maegley, Reece Marillier, Nichol Miller, Romain Pirson, Virginie Rabolli, Chad Ray, Nicole Streiner, Vince R Torti, Konstantinos Tsaparikos, Benoit J Van den Eynde, Martin Wythes, Li-Chin Yao, Xianxian Zheng, Joseph Tumang, and Manfred Kraus
Characterizing sex ratio distortion in the Collaborative Cross., Francesca Barradale
Chracterization of the effect of the Mnm(c) modifying allele on a new, CRISPR-based mouse model of SMARD1, Alex Thele
Chromatin Immunoprecipitation for Chromatin Interaction Analysis Using Paired-End-Tag (ChIA-PET) Sequencing in Tadpole Tissues., Nicolas Buisine, Xiaoan Ruan, Yijun Ruan, and Laurent M Sachs
Chromatin Interaction Analysis Using Paired-End-Tag (ChIA-PET) Sequencing in Tadpole Tissues., Nicolas Buisine, Xiaoan Ruan, Yijun Ruan, and Laurent M Sachs
Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias., John P Sundberg, Maria K Hordinsky, Wilma Bergfeld, Yolanda M Lenzy, Amy J McMichael, Angela M Christiano, Tracy McGregor, Kurt S Stenn, Raja K Sivamani, C Herbert Pratt, and Lloyd E King
Circulating serum oncologic miRNA in pediatric juvenile pilocytic astrocytoma patients predicts mural nodule volume., Markus Bookland, Min D Tang-Schomer, Eileen Gillan, and Antonina Kolmakova
Classification, Ontology, and Precision Medicine., Melissa A Haendel, Christopher G Chute, and Peter N Robinson
Comparing phenotypic variation between inbred and outbred mice., Alexander H Tuttle, Vivek M. Philip, Elissa J Chesler, and Jeffrey S Mogil
Comprehensive Endocrine-Metabolic Evaluation of Patients With Alström Syndrome Compared With BMI-Matched Controls., Joan C Han, Daniela P Reyes-Capo, Chia-Ying Liu, James C Reynolds, Evrim Turkbey, Ismail Baris Turkbey, Joy Bryant, Jan D Marshall, Juergen K. Naggert, William A Gahl, Jack A Yanovski, and Meral Gunay-Aygun
Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model., Chad A Tagge, Andrew M Fisher, Olga V Minaeva, Amanda Gaudreau-Balderrama, Juliet A Moncaster, Xiao-Lei Zhang, Mark W Wojnarowicz, Noel Casey, Haiyan Lu, Olga N Kokiko-Cochran, Sudad Saman, Maria Ericsson, Kristen D. Onos, Ronel Veksler, Vladimir V Senatorov, Asami Kondo, Xiao Z Zhou, Omid Miry, Linnea R Vose, Katisha R Gopaul, Chirag Upreti, Christopher J Nowinski, Robert C Cantu, Victor E Alvarez, Audrey M Hildebrandt, Erich S Franz, Janusz Konrad, James A Hamilton, Ning Hua, Yorghos Tripodis, Andrew T Anderson, Gareth R Howell, Daniela Kaufer, Garth F Hall, Kun P Lu, Richard M Ransohoff, Robin O Cleveland, Neil W Kowall, Thor D Stein, Bruce T Lamb, Bertrand R Huber, William C Moss, Alon Friedman, Patric K Stanton, Ann C McKee, and Lee E Goldstein
Consensus coding sequence (CCDS) database: a standardized set of human and mouse protein-coding regions supported by expert curation., Shashikant Pujar, Nuala A O'Leary, Catherine M Farrell, Jane E Loveland, Jonathan M Mudge, Craig Wallin, Carlos G Girón, Mark Diekhans, If Barnes, Ruth Bennett, Andrew E Berry, Eric Cox, Claire Davidson, Tamara Goldfarb, Jose M Gonzalez, Toby Hunt, John Jackson, Vinita Joardar, Mike P Kay, Vamsi K Kodali, Fergal J Martin, Monica McAndrews, Kelly M McGarvey, Michael Murphy, Bhanu Rajput, Sanjida H Rangwala, Lillian D Riddick, Ruth L Seal, Marie-Marthe Suner, David Webb, Sophia Zhu, Bronwen L Aken, Elspeth A Bruford, Carol J Bult, Adam Frankish, Terence Murphy, and Kim D Pruitt
Corneocyte proteomics: Applications to skin biology and dermatology., Robert H Rice, Blythe P Durbin-Johnson, Selena M Mann, Michelle Salemi, Shiro Urayama, David M Rocke, Brett S Phinney, and John P Sundberg
Cortical Network Synchrony Under Applied Electrical Field, Min D Tang-Schomer, Taylor Jackvony, and Sabato Santaniello
COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin., Fuli Wang, Hongyong Zhang, Ai-Hong Ma, Weimin Yu, Maike Zimmermann, Jun Yang, Sung Hee Hwang, Daniel Zhu, Tzu-Yin Lin, Michael Malfatti, Kenneth W Turteltaub, Paul T Henderson, Susan Airhart, Bruce D Hammock, Jianlin Yuan, Ralph W de Vere White, and Chong-Xian Pan
Cre Driver Mice Targeting Macrophages., Jiayuan Shi, Li Hua, Danielle Harmer, Peishan Li, and Guangwen Ren
Cross-organism analysis using InterMine., Rachel Lyne, Julie Sullivan, Daniela Butano, Sergio Contrino, Joshua Heimbach, Fengyuan Hu, Alex Kalderimis, Mike Lyne, Richard N Smith, Radek Štěpán, Rama Balakrishnan, Gail Binkley, Todd Harris, Kalpana Karra, Sierra A T Moxon, Steven Neuhauser, Leyla Ruzicka, Mike Cherry, Joel E Richardson, Lincoln Stein, Monte Westerfield, Elizabeth Worthey, and Gos Micklem
Culture-independent analysis of liver abscess using nanopore sequencing., Liang Gong, Yao-Ting Huang, Chee-Hong Wong, Wen-Cheng Chao, Zong-Yen Wu, Chia-Lin Wei, and Po-Yu Liu
CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse., Hui Tian, Timothy Billings, and Petko M. Petkov
Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis., Manju Sharma and Robert E Braun
Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles., Kimberly Siletti, Basile Tarchini, and A J Hudspeth
DDR: efficient computational method to predict drug-target interactions using graph mining and machine learning approaches., Rawan S Olayan, Haitham Ashoor, and Vladimir B Bajic
Deletion of a Long-Range, Kenneth R. Johnson, Leona H. Gagnon, Cong Tian, Chantal M. Longo-Guess, Benjamin E. Low, Michael V. Wiles, and Amy E Kiernan
Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice., Kenneth R. Johnson, Leona H. Gagnon, Cong Tian, Chantal M. Longo-Guess, Benjamin E. Low, Michael V. Wiles, and Amy E Kiernan
Deletion of GARP on mouse regulatory T cells is not sufficient to inhibit the growth of transplanted tumors., E Vermeersch, S Liénart, A Collignon, S Lucas, A Gallimore, C Gysemans, Derya Unutmaz, K Vanhoorelbeke, S F De Meyer, W Maes, and H Deckmyn
Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy., Caroline Choquet, Thi Hong Minh Nguyen, Pierre Sicard, Emeline Buttigieg, Thi Thom Tran, Frank Kober, Isabelle Varlet, Rachel Sturny, Mauro W Costa, Richard P Harvey, Catherine Nguyen, Pascal Rihet, Sylvain Richard, Monique Bernard, Robert G Kelly, Nathalie Lalevée, and Lucile Miquerol
Deletion of Nrip1 Extends Female Mice Longevity, Increases Autophagy, and Delays Cell Senescence., Jinyu Wang, Xundi Chen, Jared Osland, Skyler J Gerber, Chao Luan, Kristin Delfino, Leslie Goodwin, and Rong Yuan
Delivery of CRISPR-Cas9 into Mouse Zygotes by Electroporation., Wenning Qin and Haoyi Wang
Depletion of SMC5/6 sensitizes male germ cells to DNA damage., G Hwang, D E Verver, Mary Ann Handel, G Hamer, and P W Jordan
Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development., Heather E Stefanski, Yan Xing, Patricia A Taylor, Stefano Maio, Jorge Henao-Meija, Adam Williams, Richard A Flavell, Georg A Hollander, and Bruce R Blazar
Detection of correlated hidden factors from single cell transcriptomes using Iteratively Adjusted-SVA (IA-SVA)., Donghyung Lee, Anthony Cheng, Nathan Lawlor, Mohan Bolisetty, and Duygu Ucar
Determination of T Follicular Helper Cell Fate by Dendritic Cells., Jayendra Kumar Krishnaswamy, Samuel Alsén, Ulf Yrlid, Stephanie C Eisenbarth, and Adam Williams
Developmental constraint through negative pleiotropy in the zygomatic arch., Christopher J Percival, Rebecca Green, Charles C Roseman, Daniel M. Gatti, Judy Morgan, Stephen A. Murray, Leah Rae Donahue, Jessica M Mayeux, K Michael Pollard, Kunjie Hua, Daniel Pomp, Ralph Marcucio, and Benedikt Hallgrímsson
Development, Function, and Clinical Significance of Plasmacytoid Dendritic Cells in Chronic Myeloid Leukemia., Sabrina Inselmann, Ying Wang, Susanne Saussele, Lea Fritz, Christin Schütz, Magdalena Huber, Simone Liebler, Thomas Ernst, Dali Cai, Sarah Botschek, Cornelia Brendel, Raffaele A Calogero, Dinko Pavlinic, Vladimir Benes, Edison T Liu, Andreas Neubauer, Andreas Hochhaus, and Andreas Burchert
Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia., Bruce A Rosa, Taniawati Supali, Lincoln Gankpala, Yenny Djuardi, Erliyani Sartono, Yanjiao Zhou, Kerstin Fischer, John Martin, Rahul Tyagi, Fatorma K Bolay, Peter U Fischer, Maria Yazdanbakhsh, and Makedonka Mitreva
Digestion-ligation-only Hi-C is an efficient and cost-effective method for chromosome conformation capture., Da Lin, Ping Hong, Siheng Zhang, Weize Xu, Muhammad Jamal, Keji Yan, Yingying Lei, Liang Li, Yijun Ruan, Zhen F Fu, Guoliang Li, and Gang Cao
Direct-to-consumer genetic testing for breast cancer risk., Kate Reed and Emily A Edelman
Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma., Ana C deCarvalho, Hoon Kim, Laila M Poisson, Mary E Winn, Claudius Mueller, David Cherba, Julie Koeman, Sahil Seth, Alexei Protopopov, Michelle Felicella, Siyuan Zheng, Asha Multani, Yongying Jiang, Jianhua Zhang, Do-Hyun Nam, Emanuel F Petricoin, Lynda Chin, Tom Mikkelsen, and Roel G W Verhaak
Disease Ontology: improving and unifying disease annotations across species., Susan M. Bello, Mary Shimoyama, Elvira Mitraka, Stanley J F Laulederkind, Cynthia Smith, Janan T. Eppig, and Lynn M Schriml
Distribution-based measures of tumor heterogeneity are sensitive to mutation calling and lack strong clinical predictive power., Javad Noorbakhsh, Hyunsoo Kim, Sandeep Namburi, and Jeffrey H Chuang
DNA methylomes of bovine gametes and in vivo produced preimplantation embryos., Zongliang Jiang, Jianan Lin, Hong Dong, Xinbao Zheng, Sadie L Marjani, Jingyue Duan, Zhengqing Ouyang, Jingbo Chen, and Xiuchun Cindy Tian
Drivers of pancreatic islet composition., Sadie Allen
DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members., Andrew M. Garrett, Andre Khalil, David O Walton, and Robert W. Burgess
Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through, Tapan Kumar Mistri, Wibowo Arindrarto, Wei Ping Ng, Choayang Wang, Leng Hiong Lim, Lili Sun, Ian Chambers, Thorsten Wohland, and Paul Robson
Dynamics of semilattice networks with strongly connected dependency graph., Alan Veliz-Cuba and Reinhard Laubenbacher
Editorial: Axonopathy in Neurodegenerative Disease., Robert W. Burgess and Samuel D Crish
ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells., Jocelyn F Krey, Rachel A Dumont, Philip A Wilmarth, Larry L David, Kenneth R. Johnson, and Peter G Barr-Gillespie
Enterotypes in the landscape of gut microbial community composition., Paul I Costea, Falk Hildebrand, Arumugam Manimozhiyan, Fredrik Bäckhed, Martin J Blaser, Frederic D Bushman, Willem M de Vos, S Dusko Ehrlich, Claire M Fraser, Masahira Hattori, Curtis Huttenhower, Ian B Jeffery, Dan Knights, James D Lewis, Ruth E Ley, Howard Ochman, Paul W O'Toole, Christopher Quince, David A Relman, Fergus Shanahan, Shinichi Sunagawa, Jun Wang, George M. Weinstock, Gary D Wu, Georg Zeller, Liping Zhao, Jeroen Raes, Rob Knight, and Peer Bork
Etidronate prevents, but does not reverse, ectopic mineralization in a mouse model of pseudoxanthoma elasticum (, Qiaoli Li, Joshua Kingman, John P Sundberg, Michael A Levine, and Jouni Uitto
Evaluating machine learning approaches for deciding relevance of ArrayExpress experiments for the Gene Expression Database., Yasmine Boukataya
Evaluating the therapeutic effect of 2-Deoxy-D-glucose on various cancer models., Nathan Labrie
Evaluation of concordance of variant to phenotype associations in mouse and human., Cassandra Alvarado
Evaluation of exome filtering techniques for the analysis of clinically relevant genes., Kristin D Kernohan, Taila Hartley, Najmeh Alirezaie, Care4Rare Canada Consortium, Peter N Robinson, David A Dyment, and Kym M Boycott
Evolving Insights into the Molecular Neuropathology of Diffuse Gliomas in Adults., Floris P Barthel, Kevin C Johnson, Pieter Wesseling, and Roel G W Verhaak
Examining the role of Dyrkl a in the development and function of inhibitory neurons., Rachel V. Levy
Exploring autophagy with Gene Ontology., Paul Denny, Marc Feuermann, David P. Hill, Ruth C Lovering, Helene Plun-Favreau, and Paola Roncaglia
Exploring autophagy with Gene Ontology., Paul Denny, Marc Feuermann, David P. Hill, Ruth C Lovering, Helene Plun-Favreau, and Paola Roncaglia
Extensive Gene Amplification as a Mechanism for Piperacillin-Tazobactam Resistance in Escherichia coli., Lisa M Schechter, David P Creely, Cherilyn D Garner, Dee Shortridge, Hoan Nguyen, Lei Chen, Blake M Hanson, Erica Sodergren Weinstock, George M. Weinstock, W Michael Dunne, Alex van Belkum, and Shana R Leopold
Extracellular vesicles in DLBCL provide abundant clues to aberrant transcriptional programming and genomic alterations., Sarah C Rutherford, Angela A Fachel, Sheng Li, Seema Sawh, Ashlesha Muley, Jennifer Ishii, Ashish Saxena, Pilar M Dominguez, Eloisi Caldas Lopes, Xabier Agirre, Nyasha Chambwe, Fabian Correa, Yanwen Jiang, Kristy L Richards, Doron Betel, and Rita Shaknovich
FAR2 is Associated with Kidney Disease in Mice and Humans., Grant Backer, Sean Eddy, Susan Sheehan, Yuka Takemon, Anna Reznichenko, Holly S Savage, Matthias Kretzler, and Ron Korstanje
Fay Lawson Oral History, Fay Lawson
Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions., Anant Chopra, Matthew L Kutys, Kehan Zhang, William J Polacheck, Calvin C Sheng, Rebeccah J Luu, Jeroen Eyckmans, J Travis Hinson, Jonathan G Seidman, Christine E Seidman, and Christopher S Chen
Frataxin-deficient neurons and mice models of Friedreich ataxia are improved by TAT-MTScs-FXN treatment., Elena Britti, Fabien Delaspre, Anat Feldman, Melissa Osborne, Hagar Greif, Jordi Tamarit, and Joaquim Ros
Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing., Xin Chen, Lina Kozhaya, Cihan Tastan, Lindsey Placek, Mikail Dogan, Meghan Horne, Rebecca Abblett, Ece Karhan, Martin Vaeth, Stefan Feske, and Derya Unutmaz
Functional Redundancy of DICER Cofactors TARBP2 and PRKRA During Murine Embryogenesis Does Not Involve miRNA Biogenesis., Sri Ramulu N Pullagura, F William Buaas, Nichelle Gray, Lindsey C Krening, Anuj Srivastava, and Robert E Braun
FusorSV: an algorithm for optimally combining data from multiple structural variation detection methods., Timothy Becker, Wan-Ping Lee, Joseph Leone, Qihui Zhu, Chengsheng Zhang, Silvia Liu, Jack Sargent, Kritika Shanker, Adam Mil-Homens, Eliza Cerveira, Mallory Ryan, Jane Cha, Fabio C P Navarro, Timur Galeev, Mark Gerstein, Ryan E Mills, Dong-Guk Shin, Charles Lee, and Ankit Malhotra
Gearing up to handle the mosaic nature of life in the quest for orthologs., Kristoffer Forslund, Cecile Pereira, Salvador Capella-Gutierrez, Alan Sousa da Silva, Adrian Altenhoff, Jaime Huerta-Cepas, Matthieu Muffato, Mateus Patricio, Klaas Vandepoele, Ingo Ebersberger, Judith A. Blake, Jesualdo Tomás Fernández Breis, The Quest for Orthologs Consortium, Brigitte Boeckmann, Toni Gabaldón, Erik Sonnhammer, Christophe Dessimoz, and Suzanna Lewis
Gene Ontology Consortium: going forward., Gene Ontology Consortium, Judith A. Blake, Karen R. Christie, Mary E. Dolan, Harold J. Drabkin, David P. Hill, Li Ni, Dmitry Sitnikov, and et .. al
Gene Therapy with an Adeno-Associated Viral Vector Expressing Human Interleukin-2 Alters Immune System Homeostasis in Humanized Mice., Philip A Durost, Ken-Edwin Aryee, Fatima Manzoor, Roland M Tisch, Christian Mueller, Agata Jurczyk, Leonard D. Shultz, and Michael A Brehm
Genetic background influences susceptibility to chemotherapy-induced hematotoxicity., Daniel M. Gatti, S N Weber, N C Goodwin, F Lammert, and Gary A Churchill
Genetic drivers of insulin homeostasis., Takanao Ishimura
Genetic Drivers of Pancreatic Islet Function., Mark P Keller, Daniel M. Gatti, Kathryn L Schueler, Mary E Rabaglia, Donnie S Stapleton, Petr Simecek, Matthew J Vincent, Sadie Allen, Aimee Teo Broman, Rhonda Bacher, Christina Kendziorski, Karl W Broman, Brian S Yandell, Gary A Churchill, and Alan D Attie
Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats., Gregory R Keele, Jeremy W Prokop, Hong He, Katie Holl, John Littrell, Aaron Deal, Sanja Francic, Leilei Cui, Daniel M. Gatti, Karl W Broman, Michael Tschannen, Shirng-Wern Tsaih, Maie Zagloul, Yunjung Kim, Brittany Baur, Joseph Fox, Melanie Robinson, Shawn Levy, Michael J Flister, Richard Mott, William Valdar, and Leah C Solberg Woods
Genetic Models of Macrophage Depletion., Li Hua, Jiayuan Shi, Leonard D. Shultz, and Guangwen Ren
Genome-wide association for testis weight in the diversity outbred mouse population., Joshua T Yuan, Daniel M. Gatti, Vivek M. Philip, Steven Kasparek, Andrew M Kreuzman, Benjamin Mansky, Kayvon Sharif, Dominik Taterra, Walter M Taylor, Mary Thomas, Jeremy O Ward, Andrew Holmes, Elissa J Chesler, and Clarissa C Parker
Genomic Approach to Understand the Association of DNA Repair with Longevity and Healthy Aging Using Genomic Databases of Oldest-Old Population., Yeo Jin Kim, Hyun Soo Kim, and Young Rok Seo
Genomic Profiling of T-Cell Neoplasms Reveals Frequent, Allison Greenplate, Kai Wang, Rati M Tripathi, Norma Palma, Siraj M Ali, Phil J Stephens, Vincent A Miller, Yu Shyr, Yan Guo, Nishitha M Reddy, Lina Kozhaya, Derya Unutmaz, Xueyan Chen, Jonathan M Irish, and Utpal P Davé
Genomic Profiling of Two Histologically Distinct Rare Urothelial Cancers in a Clinical Setting to Identify Potential Therapeutic Options for Treatment and Management of Disease., Andrew N Hesse, William Fabricius, Christian A Thomas, Ramesh Gaindh, Robert Christman, Pavalan Selvam, Matthew Prego, Gregory Lewis, Jasmina Uvalic, Daniel Bergeron, Shelbi Burns, Bridgette Sisson, Kevin Kelly, Jens Rueter, and Honey V Reddi
Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium., The GLASS Consortium, Hoon Kim, and Roel G W Verhaak
Harmonising phenomics information for a better interoperability in the rare disease field., Sylvie Maiella, Annie Olry, Marc Hanauer, Valérie Lanneau, Halima Lourghi, Bruno Donadille, Charlotte Rodwell, Sebastian Köhler, Dominik Seelow, Simon Jupp, Helen Parkinson, Tudor Groza, Michael Brudno, Peter N Robinson, and Ana Rath
Hematopoietic cells as site of first-pass catabolism after subcutaneous dosing and contributors to systemic clearance of a monoclonal antibody in mice., Wolfgang F Richter, Gregory J. Christianson, Nicolas Frances, Hans Peter Grimm, Gabriele Proetzel, and Derry C. Roopenian
Hierarchical analysis of RNA-seq reads improves the accuracy of allele-specific expression., Narayanan Raghupathy, Kwangbom Choi, Matthew J Vincent, Glen L Beane, Keith Sheppard, Steven C. Munger, Ron Korstanje, Fernando Pardo-Manual de Villena, and Gary Churchill
High-resolution deconstruction of evolution induced by chemotherapy treatments in breast cancer xenografts., Hyunsoo Kim, Pooja A Kumar, Francesca Menghi, Javad Noorbakhsh, Eliza Cerveira, Mallory Ryan, Qihui Zhu, Guruprasad Ananda, Joshy George, Henry C Chen, Susan Mockus, Chengsheng Zhang, Yan Yang, James G. Keck, Radha Krishna Murthy Karuturi, Carol J Bult, Charles Lee, Edison Liu, and Jeffrey H Chuang
High throughput in situ metagenomic measurement of bacterial replication at ultra-low sequencing coverage., Akintunde Emiola and Julia Oh
HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression., Jennifer Schloss, Riyasat Ali, Jeremy Racine, Harry D Chapman, David V. Serreze, and Teresa P DiLorenzo
Homeward bound: The capacity of the food hoarding task to assess complex cognitive processes., Shawn S Winter, Philip A Blankenship, and Max L Mehlman
Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss Are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer., Dale W Garsed, Kathryn Alsop, Sian Fereday, Catherine Emmanuel, Catherine J Kennedy, Dariush Etemadmoghadam, Bo Gao, Val Gebski, Valérie Garès, Elizabeth L Christie, Maartje C A Wouters, Katy Milne, Joshy George, Ann-Marie Patch, Jason Li, Gisela Mir Arnau, Timothy Semple, Sreeja R Gadipally, Yoke-Eng Chiew, Joy Hendley, Thomas Mikeska, Giada V Zapparoli, Kaushalya Amarasinghe, Sean M Grimmond, John V Pearson, Nicola Waddell, Jillian Hung, Colin J R Stewart, Raghwa Sharma, Prue E Allan, Peter F Rambau, Orla McNally, Linda Mileshkin, Anne Hamilton, Sumitra Ananda, Marisa Grossi, Paul A Cohen, Yee C Leung, Robert M Rome, Philip Beale, Penny Blomfield, Michael Friedlander, Alison Brand, Alexander Dobrovic, Martin Köbel, Paul Harnett, Brad H Nelson, David D L Bowtell, and Anna deFazio
Human dental stem cell derived transgene-free iPSCs generate functional neurons via embryoid body-mediated and direct induction methods., Ikbale El Ayachi, Jun Zhang, Xiao-Ying Zou, Dong Li, Zongdong Yu, Wei Wei, Kristen M S O'Connell, and George T-J Huang
Human immune cell engraftment does not alter development of severe acute Rift Valley fever in mice., Jessica R Spengler, Anita K McElroy, Jessica R Harmon, JoAnn D Coleman-McCray, Stephen R Welch, James G. Keck, Stuart T Nichol, and Christina F Spiropoulou
Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy., Minan Wang, Li-Chin Yao, Mingshan Cheng, Danying Cai, Jan Martinek, Chong-Xian Pan, Wei Shi, Ai-Hong Ma, Ralph W De Vere White, Susan Airhart, Edison T Liu, Jacques Banchereau, Michael A Brehm, Dale L Greiner, Leonard D. Shultz, Karolina Palucka, and James G. Keck
Humanizing the mdx mouse model of DMD: the long and the short of it., Nora Yucel, Alex C Chang, John W Day, Nadia Rosenthal, and Helen M Blau
Identification of a Novel microRNA Profile in Pediatric Cancer Patients treated with Anthracycline Chemotherapy., Kelsie E Oatmen, Olga H Toro-Salazar, Kristine Hauser, Kia N Zellars, Kathryn C Mason, Kan Hor, Eileen Gillan, Caroline J Zeiss, Daniel M. Gatti, and Francis G Spinale
Identification of genes required for eye development by high-throughput screening of mouse knockouts., Bret A Moore, Brian C Leonard, Lionel Sebbag, Sydney G Edwards, Ann Cooper, Denise M Imai, Ewan Straiton, Luis Santos, Christopher Reilly, Stephen M Griffey, Lynette Bower, David Clary, Jeremy Mason, Michel J Roux, Hamid Meziane, Yann Herault, Colin McKerlie, Ann M Flenniken, Lauryl M J Nutter, Zorana Berberovic, Celeste Owen, Susan Newbigging, Hibret Adissu, Mohammed Eskandarian, Chih-Wei Hsu, Sowmya Kalaga, Uchechukwu Udensi, Chinwe Asomugha, Ritu Bohat, Juan J Gallegos, John R Seavitt, Jason D Heaney, Arthur L Beaudet, Mary E Dickinson, Monica J Justice, Vivek M. Philip, Vivek Kumar, Karen L. Svenson, Robert E Braun, Sara Wells, Heather Cater, Michelle Stewart, Sharon Clementson-Mobbs, Russell Joynson, Xiang Gao, Tomohiro Suzuki, Shigeharu Wakana, Damian Smedley, J K Seong, Glauco Tocchini-Valentini, Mark Moore, Colin Fletcher, Natasha Karp, Ramiro Ramirez-Solis, Jacqueline K White, Martin Hrabe de Angelis, Wolfgang Wurst, Sara M Thomasy, Paul Flicek, Helen Parkinson, Steve D M Brown, Terrence F Meehan, Patsy M. Nishina, Stephen A. Murray, Mark P. Krebs, Ann-Marie Mallon, K C Kent Lloyd, Christopher J Murphy, and Ala Moshiri
Identification of genetic elements in metabolism by high-throughput mouse phenotyping., Jan Rozman, Birgit Rathkolb, Manuela A Oestereicher, Christine Schütt, Aakash Chavan Ravindranath, Stefanie Leuchtenberger, Sapna Sharma, Martin Kistler, Monja Willershäuser, Robert Brommage, Terrence F Meehan, Jeremy Mason, Hamed Haselimashhadi, Tertius Hough, Ann-Marie Mallon, Sara Wells, Luis Santos, Christopher J Lelliott, Jacqueline K White, Tania Sorg, Marie-France Champy, Lynette R Bower, Corey L Reynolds, Ann M Flenniken, Stephen A. Murray, Lauryl M J Nutter, Karen L. Svenson, David West, Glauco P Tocchini-Valentini, Arthur L Beaudet, Fatima Bosch, Robert E Braun, Michael S Dobbie, Xiang Gao, Yann Herault, Ala Moshiri, Bret A Moore, K C Kent Lloyd, Colin McKerlie, Hiroshi Masuya, Nobuhiko Tanaka, Paul Flicek, Helen E Parkinson, Radislav Sedlacek, Je Kyung Seong, Chi-Kuang Leo Wang, Mark Moore, Steve D Brown, Matthias H Tschöp, Wolfgang Wurst, Martin Klingenspor, Eckhard Wolf, Johannes Beckers, Fausto Machicao, Andreas Peter, Harald Staiger, Hans-Ulrich Häring, Harald Grallert, Monica Campillos, Holger Maier, Helmut Fuchs, Valerie Gailus-Durner, Thomas Werner, and Martin Hrabe de Angelis
Identification of non-histone protein targets of KMT5A in hematopoietic cells., Teniola Idowu
Identifying addiction related genes through operant sensation seeking in a BXD recombinant inbred panel., Padam Kumar
Identifying genetic variation with diet and sex-dependent effects in diversity outbred mice., Douglas Perkins
Identifying noncoding risk variants using disease-relevant gene regulatory networks., Long Gao, Yasin Uzun, Peng Gao, Bing He, Xiaoke Ma, Jiahui Wang, Shizhong Han, and Kai Tan
IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer., Te-Chia Wu, Kangling Xu, Jan Martinek, Robyn R Young, Romain Banchereau, Joshy George, Jacob Turner, Kyung In Kim, Sandra Zurawski, Xuan Wang, Derek Blankenship, Hannah M Brookes, Florentina Marches, Gerlinde Obermoser, Elizabeth Lavecchio, Maren K Levin, Sookyoung Bae, Cheng-Han Chung, Jennifer L Smith, Alma-Martina Cepika, Kyp L Oxley, George J Snipes, Jacques Banchereau, Virginia Pascual, Joyce O'Shaughnessy, and A. Karolina Palucka
Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model., Qilai Long, Tzu-Yin Lin, Yee Huang, Xiaocen Li, Ai-Hong Ma, Hongyong Zhang, Randy Carney, Susan Airhart, Kit S Lam, Ralph W deVere White, Chong-Xian Pan, and Yuanpei Li
Immunodeficiency in a Child with Alström Syndrome., Taha Resid Ozdemir, Neslihan Edeer Karaca, Jan Davis Marshall, Necil Kutukculer, Guzide Aksu, Riza Koksal Ozgul, Aysegul Ozanturk, Esra Isik, Bilcag Akgun, Hamiyet Hekimci Ozdemir, Sukran Darcan, Ferda Ozkinay, and Ozgur Cogulu
Immunomodulatory interventions in myocardial infarction and heart failure: a systematic review of clinical trials and meta-analysis of IL-1 inhibition., Mona Panahi, Angelos Papanikolaou, Azam Torabi, Ji-Gang Zhang, Habib Khan, Ali Vazir, Muneer G. Hasham, John G F Cleland, Nadia Rosenthal, Sian E Harding, and Susanne Sattler
Immunotherapy: The path to win the war on cancer?, Suzanne L Topalian, Jedd D Wolchok, Timothy A Chan, Ira Mellman, Karolina Palucka, Jacques Banchereau, Steven A Rosenberg, and K Dane Wittrup
Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development., Jeremy Racine, Isabel Stewart, Jeremy Ratiu, Gregory J. Christianson, Emily Lowell, Kelsay Helm, Jennifer Allocco, Richard S. Maser, Yi-Guang Chen, Cathleen Lutz, Derry C. Roopenian, Jennifer Schloss, Teresa P DiLorenzo, and David V. Serreze
Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology., Ruth C Lovering, Paola Roncaglia, Douglas G Howe, Stanley J F Laulederkind, Varsha K Khodiyar, Tanya Z Berardini, Susan Tweedie, Rebecca E Foulger, David Osumi-Sutherland, Nancy H Campbell, Rachael P Huntley, Philippa J Talmud, Judith A. Blake, Ross Breckenridge, Paul R Riley, Pier D Lambiase, Perry M Elliott, Lucie Clapp, Andrew Tinker, and David P. Hill
Increased Reactive Oxygen Species and Cell Cycle Defects Contribute to Anemia in the RASA3 Mutant Mouse Model s, Emily S Hartman, Elena C Brindley, Julien Papoin, Steven L. Ciciotte, Yue Zhao, Luanne L. Peters, and Lionel Blanc
Inferring Transmission Histories of Rare Alleles in Population-Scale Genealogies., Dominic Nelson, Claudia Moreau, Marianne de Vriendt, Yixiao Zeng, Christoph Preuss, Hélène Vézina, Emmanuel Milot, Gregor Andelfinger, Damian Labuda, and Simon Gravel
Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells., Seung-Chul Choi, Anton A Titov, Georges Abboud, Howard R Seay, Todd M Brusko, Derry C. Roopenian, Shahram Salek-Ardakani, and Laurence Morel
Inhibition of Glycolysis Reduces Disease Severity in an Autoimmune Model of Rheumatoid Arthritis., Georges Abboud, Seung-Chul Choi, Nathalie Kanda, Leilani Zeumer-Spataro, Derry C. Roopenian, and Laurence Morel
Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis., Zhigang Cai, Jonathan J Kotzin, Baskar Ramdas, Sisi Chen, Sai Nelanuthala, Lakshmi Reddy Palam, Ruchi Pandey, Raghuveer Singh Mali, Yan Liu, Mark R Kelley, George Sandusky, Morvarid Mohseni, Adam Williams, Jorge Henao-Mejia, and Reuben Kapur
Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery., A L Wollenberg, T M O'Shea, J H Kim, Anne M Czechanski, Laura G Reinholdt, M V Sofroniew, and T J Deming
Integrative annotation and knowledge discovery of kinase post-translational modifications and cancer-associated mutations through federated protein ontologies and resources., Liang-Chin Huang, Karen E Ross, Timothy R Baffi, Harold J. Drabkin, Krzysztof J Kochut, Zheng Ruan, Peter D'Eustachio, Daniel McSkimming, Cecilia Arighi, Chuming Chen, Darren A Natale, Cynthia Smith, Pascale Gaudet, Alexandra C Newton, Cathy Wu, and Natarajan Kannan
Integrative Personal Omics Profiles during Periods of Weight Gain and Loss., Brian D Piening, Wenyu Zhou, Kévin Contrepois, Hannes Röst, Gucci Jijuan Gu Urban, Tejaswini Mishra, Blake M Hanson, Eddy J Bautista, Shana Leopold, Christine Y Yeh, Daniel Spakowicz, Imon Banerjee, Cynthia Chen, Kimberly Kukurba, Dalia Perelman, Colleen Craig, Elizabeth Colbert, Denis Salins, Shannon Rego, Sunjae Lee, Cheng Zhang, Jessica Wheeler, M Reza Sailani, Liang Liang, Charles Abbott, Mark Gerstein, Adil Mardinoglu, Ulf Smith, Daniel L Rubin, Sharon Pitteri, Erica Sodergren Weinstock, Tracey L McLaughlin, George M. Weinstock, and Michael P Snyder
Interaction between the microbiome and TP53 in human lung cancer., K Leigh Greathouse, James R White, Ashely J Vargas, Valery V Bliskovsky, Jessica A Beck, Natalia von Muhlinen, Eric C Polley, Elise D Bowman, Mohammed A Khan, Ana I Robles, Tomer Cooks, Bríd M Ryan, Noah Padgett, Amiran H Dzutsev, Giorgio Trinchieri, Marbin A Pineda, Sven Bilke, Paul S Meltzer, Alexis N Hokenstad, Tricia M Stickrod, Marina R Walther-Antonio, Joshua P Earl, Joshua C Mell, Jaroslaw E Krol, Sergey V Balashov, Archana S Bhat, Garth D Ehrlich, Alex Valm, Clayton Deming, Sean Conlan, Julia Oh, Julie A Segre, and Curtis C Harris
Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota., Francesca Cignarella, Claudia Cantoni, Laura Ghezzi, Amber Salter, Yair Dorsett, Lei Chen, Daniel S Phillips, George M. Weinstock, Luigi Fontana, Anne H Cross, Yanjiao Zhou, and Laura Piccio
Introduction to mammalian genome special issue: the combined role of genetics and environment relevant to human disease outcomes., Ivan Rusyn, Steven R Kleeberger, Kimberly A McAllister, John E French, and Karen L. Svenson
Investigating the role of Rab34 in regulating Hedgehog signaling pathway activity., Amelia Meles
In vitro 3D regeneration-like growth of human patient brain tissue., Min D Tang-Schomer, W B Wu, D L Kaplan, and M J Bookland
In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions., S R Burstein, F Valsecchi, H Kawamata, M Bourens, R Zeng, Aamir Zuberi, T A Milner, S M Cloonan, Cathleen Lutz, A Barrientos, and G Manfredi
Is RNA editing involved in the full recovery of kidneys in Black Bears after hibernation., Selena Neptune-Bear
JEPEGMIX2: improved gene-level joint analysis of eQTLs in cosmopolitan cohorts., Chris Chatzinakos, Donghyung Lee, Bradley T Webb, Vladimir I Vladimirov, Kenneth S Kendler, and Silviu-Alin Bacanu
Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice., Jeffrey M. Harder, Pete A. Williams, Ileana Soto, Nicole E Foxworth, Kimberly A Fernandes, Nelson F Freeburg, Richard T Libby, and Simon W M John
Joint principal trend analysis for longitudinal high-dimensional data., Yuping Zhang and Zhengqing Ouyang
King Gustaf Awards Nobel Prize to George Davis Snell, George Davis Snell
Lithium induces aerobic glycolysis and glutaminolysis in collecting duct principal cells., Mohammad Alsady, Theun de Groot, Marleen L A Kortenoeven, Claudia Carmone, Kim Neijman, Melissa Bekkenkamp-Grovenstein, Udo Engelke, Ron Wevers, Ruben Baumgarten, Ron Korstanje, and Peter M T Deen
Living inside the box: environmental effects on mouse models of human disease., John P Sundberg and Paul N Schofield
Low Peripheral T Follicular Helper Cells in Perinatally HIV-Infected Children Correlate With Advancing HIV Disease., Bret McCarty, Mussa Mwamzuka, Fatma Marshed, Matthew Generoso, Patricia Alvarez, Tiina Ilmet, Adam Kravietz, Aabid Ahmed, William Borkowsky, Derya Unutmaz, and Alka Khaitan
Machine learning in the observation of behavioral phenotypes., Gabrielle Cohn
Mean-Variance QTL Mapping Identifies Novel QTL for Circadian Activity and Exploratory Behavior in Mice., Robert W Corty, Vivek Kumar, Lisa M Tarantino, Joseph S Takahashi, and William Valdar
Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling., Enrique J Cobos, Chelsea A Nickerson, Fuying Gao, Vijayendran Chandran, Inmaculada Bravo-Caparrós, Rafael González-Cano, Priscilla Riva, Nick A Andrews, Alban Latremoliere, Corey R Seehus, Gloria Perazzoli, Francisco R Nieto, Nicole Joller, Michio W Painter, Chi Him Eddie Ma, Takao Omura, Elissa J Chesler, Daniel H Geschwind, Giovanni Coppola, Manu Rangachari, Clifford J Woolf, and Michael Costigan
Mechanistic insights into liposarcoma progression., Ellen Kendall
Meiosis: the chromosomal foundation of reproduction., Ewelina Bolcun-Filas and Mary Ann Handel
Meta-analysis of human gene expression in response to Mycobacterium tuberculosis infection reveals potential therapeutic targets., Zhang Wang, Seda Arat, Michal Magid-Slav, and James R Brown
Meta-analysis of the lung microbiota in pulmonary tuberculosis., Bo-Young Hong, Joseph N Paulson, O Colin Stine, George M. Weinstock, and Jorge L Cervantes
Metabolic profiling of follistatin overexpression: a novel therapeutic strategy for metabolic diseases., Rajan Singh, Shehla Pervin, Se-Jin Lee, Alan Kuo, Victor Grijalva, John David, Laurent Vergnes, and Srinivasa T Reddy
Methodology, Criteria, and Characterization of Patient-Matched Thyroid Cell Lines and Patient-Derived Tumor Xenografts., Laura A Marlow, Stephen D Rohl, James L Miller, Jeffery A Knauf, James A Fagin, Mabel Ryder, Dragana Milosevic, Brian C Netzel, Stefan K Grebe, Honey V Reddi, Robert C Smallridge, and John A Copland
Modeling the differentiation of induced pluripotent stem cells using single cell RNA sequencing data, Tossapol Pholcharee
Model organism data evolving in support of translational medicine., Douglas G Howe, Judith A. Blake, Yvonne M Bradford, Carol J Bult, Brian R Calvi, Stacia R Engel, James A. Kadin, Thomas C Kaufman, Ranjana Kishore, Stanley J F Laulederkind, Suzanna E Lewis, Sierra A T Moxon, Joel E Richardson, and Cynthia Smith
Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma., Fengdan Ye, Dongya Jia, Mingyang Lu, Herbert Levine, and Michael W Deem
Modulation of immune and stromal cells by cancer immunotherapy and chemotherapy in mice., Kevin Hayes
Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse., Cynthia Smith, Judith A. Blake, James A. Kadin, Joel E Richardson, Carol J Bult, and Mouse Genome Database Group
Mouse Genome Informatics (MGI) Is the International Resource for Information on the Laboratory Mouse., MeiYee Law and David R. Shaw
Mouse Models for Cancer Immunotherapy Research., Brian Olson, Yadi Li, Yu Lin, Edison T Liu, and Akash Patnaik
Mouse models of ALS: Past, present and future., Cathleen Lutz
Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice., Molly A. Bogue, Stephen C. Grubb, David O Walton, Vivek M. Philip, Georgi Kolishovski, Timothy M Stearns, Matthew H Dunn, Daniel A Skelly, Beena Kadakkuzha, Gregg TeHennepe, Govindarajan Kunde-Ramamoorthy, and Elissa J Chesler
Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error., Seyyedhassan Paylakhi, Cassandre Labelle-Dumais, Nicholas G Tolman, Michael A Sellarole, Yusef Seymens, Joseph Saunders, Hesham Lakosha, Wilhelmine N de Vries, Andrew C Orr, Piotr Topilko, Simon W M John, and K Saidas Nair
Multicolor Fluorescence In Situ Hybridization (FISH) Approaches for Simultaneous Analysis of the Entire Human Genome., Chengsheng Zhang, Eliza Cerveira, Willem Rens, Fengtang Yang, and Charles Lee
MultiDCoX: Multi-factor analysis of differential co-expression., Herty Liany, Jagath C Rajapakse, and Radha Krishna Murthy Karuturi
Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis., Danitza Nébor, Joel H. Graber, Steven L. Ciciotte, Ray F. Robledo, Julien Papoin, Emily Hartman, Kevin R Gillinder, Andrew C Perkins, James J Bieker, Lionel Blanc, and Luanne L. Peters
Mutations in DNA repair genes are associated with increased neo-antigen load and activated T cell infiltration in lung adenocarcinoma., Young Kwang Chae, Jonathan F Anker, Preeti Bais, Sandeep Namburi, Francis J Giles, and Jeffrey H Chuang
Nicotinamide treatment robustly protects from inherited mouse glaucoma., Pete A. Williams, Jeffrey M. Harder, Brynn H Cardozo, Nicole E Foxworth, and Simon W M John
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network., David J Anderson, David I Kaplan, Katrina M Bell, Katerina Koutsis, John M Haynes, Richard J Mills, Dean G Phelan, Elizabeth L Qian, Ana Rita Leitoguinho, Deevina Arasaratnam, Tanya Labonne, Elizabeth S Ng, Richard P Davis, Simona Casini, Robert Passier, James E Hudson, Enzo R Porrello, Mauro W Costa, Arash Rafii, Clare L Curl, Lea M Delbridge, Richard P Harvey, Alicia Oshlack, Michael M Cheung, Christine L Mummery, Stephen Petrou, Andrew G Elefanty, Edouard G Stanley, and David A Elliott
Nobel Prize Box, George Davis Snell
Nobel Prize Document Cover, George Davis Snell
Nobel Prize Medal (back), George Davis Snell
Nobel Prize Medal (front), George Davis Snell
Nondestructive, label-free characterization of mechanical microheterogeneity in biomimetic materials., Devina Jaiswal, Min D Tang-Schomer, Disha Sood, David L Kaplan, and Kazunori Hoshino
Novel Endomorphin Analogs Are More Potent and Longer-Lasting Analgesics in Neuropathic, Inflammatory, Postoperative, and Visceral Pain Relative to Morphine., Amy K Feehan, Jenny Morgenweck, Xing Zhang, Ariel T Amgott-Kwan, and James E Zadina
Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusions., Ryo Tamura, Kosuke Yoshihara, Tetsuya Saito, Ryosuke Ishimura, Juan Emmanuel Martínez-Ledesma, Hu Xin, Tatsuya Ishiguro, Yutaro Mori, Kaoru Yamawaki, Kazuaki Suda, Seiya Sato, Hiroaki Itamochi, Teiichi Motoyama, Yoichi Aoki, Shujiro Okuda, Cristine R Casingal, Hirofumi Nakaoka, Ituro Inoue, Roel G W Verhaak, Masaaki Komatsu, and Takayuki Enomoto
Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice., Jianjun Hu, Fengyun Sun, and Mary Ann Handel
Obesity and obesogenic growth are both highly heritable and modified by diet in a nonhuman primate model, the African green monkey (Chlorocebus aethiops sabaeus)., C A Schmitt, S K Service, A J Jasinska, T D Dyer, M J Jorgensen, R M Cantor, George M. Weinstock, J Blangero, J R Kaplan, and N B Freimer
"Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic., Heather Gordish-Dressman, Raffaella Willmann, Laura Dalle Pazze, Arati Kreibich, Maaike van Putten, Ahlke Heydemann, Laurent P. Bogdanik, Cathleen Lutz, Kay Davies, Alexis R Demonbruen, Dongsheng Duan, David Elsey, So-Ichiro Fukada, Mahasweta Girgenrath, J Patrick Gonzalez, Miranda D Grounds, Andy Nichols, Terry Partridge, Marco Passini, Francesca Sanarica, Frederick J Schnell, Dominic J Wells, Toshifumi Yokota, Courtney S Young, Zhong Zhong, Christopher Spurney, Melissa Spencer, Annamaria De Luca, Kanneboyina Nagaraju, and Annemieke Aartsma-Rus
Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice., Jing Guo, Teng Zhang, Yueshuai Guo, Tao Sun, Hui Li, Xiaoyun Zhang, Hong Yin, Guangyi Cao, Yaoxue Yin, Hao Wang, Lanying Shi, Xuejiang Guo, Jiahao Sha, John J. Eppig, and You-Qiang Su
Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma., Seçkin Akgül, Yinghua Li, Siyuan Zheng, Marcel Kool, Daniel M Treisman, Chaoyang Li, Yuan Wang, Susanne Gröbner, Tsuneo Ikenoue, Yiping Shen, Sandra Camelo-Piragua, Gerald Tomasek, Sebastian Stark, Vinay Guduguntla, James F Gusella, Kun-Liang Guan, Stefan M Pfister, Roel G W Verhaak, and Yuan Zhu
ORAI1 mutations abolishing store-operated Ca, Jayson Lian, Mario Cuk, Sascha Kahlfuss, Lina Kozhaya, Martin Vaeth, Frédéric Rieux-Laucat, Capucine Picard, Melina J Benson, Antonia Jakovcevic, Karmen Bilic, Iva Martinac, Peter Stathopulos, Imre Kacskovics, Thomas Vraetz, Carsten Speckmann, Stephan Ehl, Thomas Issekutz, Derya Unutmaz, and Stefan Feske
Oral Pathobiont Activates Anti-Apoptotic Pathway, Promoting both Immune Suppression and Oncogenic Cell Proliferation., Pachiappan Arjunan, Mohamed M Meghil, Wenhu Pi, Jinxian Xu, Liwei Lang, Ahmed El-Awady, William Sullivan, Mythilypriya Rajendran, Mariana Sousa Rabelo, Tong Wang, Omnia K Tawfik, Govindarajan Kunde-Ramamoorthy, Nagendra Singh, Thangaraju Muthusamy, Cristiano Susin, Yong Teng, Roger M Arce, and Christopher W Cutler
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours., Xiaotu Ma, Yu Liu, Yanling Liu, Ludmil B Alexandrov, Michael N Edmonson, Charles Gawad, Xin Zhou, Yongjin Li, Michael C Rusch, John Easton, Robert Huether, Veronica Gonzalez-Pena, Mark R Wilkinson, Leandro C Hermida, Sean Davis, Edgar Sioson, Stanley Pounds, Xueyuan Cao, Rhonda E Ries, Zhaoming Wang, Xiang Chen, Li Dong, Sharon J Diskin, Malcolm A Smith, Jaime M Guidry Auvil, Paul S Meltzer, Ching C Lau, Elizabeth J Perlman, John M Maris, Soheil Meshinchi, Stephen P Hunger, Daniela S Gerhard, and Jinghui Zhang
Patient-derived xenografts of low-grade B-cell lymphomas demonstrate roles of the tumor microenvironment., W Richard Burack, Janice M Spence, John P Spence, Stephen A Spence, Philip J Rock, Gautam N Shenoy, Leonard D. Shultz, Richard B Bankert, and Steven H Bernstein
Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy., Jin-Ku Lee, Zhaoqi Liu, Jason K Sa, Sang Shin, Jiguang Wang, Mykola Bordyuh, Hee Jin Cho, Oliver Elliott, Timothy Chu, Seung Won Choi, Daniel I S Rosenbloom, In-Hee Lee, Yong Jae Shin, Hyun Ju Kang, Donggeon Kim, Sun Young Kim, Moon-Hee Sim, Jusun Kim, Taehyang Lee, Yun Jee Seo, Hyemi Shin, Mijeong Lee, Sung Heon Kim, Yong-Jun Kwon, Jeong-Woo Oh, Minsuk Song, Misuk Kim, Doo-Sik Kong, Jung Won Choi, Ho Jun Seol, Jung-Il Lee, Seung Tae Kim, Joon Oh Park, Kyoung-Mee Kim, Sang-Yong Song, Jeong-Won Lee, Hee-Cheol Kim, Jeong Eon Lee, Min Gew Choi, Sung Wook Seo, Young Mog Shim, Jae Ill Zo, Byong Chang Jeong, Yeup Yoon, Gyu Ha Ryu, Nayoung K D Kim, Joon Seol Bae, Woong-Yang Park, Jeongwu Lee, Roel G W Verhaak, Antonio Iavarone, Jeeyun Lee, Raul Rabadan, and Do-Hyun Nam
Photoreceptor degeneration in a new Cacna1f mutant mouse model., Xufeng Dai, Shiyi Pang, Jieping Wang, Bernard FitzMaurice, Jijing Pang, and Bo Chang
Physician-diagnosed eczema is an independent risk factor for incident mouse skin test sensitization in adults., Torie Grant, Jennifer Dantzer, Corinne Keet, Roger Peng, Beverly J Paigen, Mary Krevans, Karol Hagberg, Jean Curtin-Brosnan, Wayne Shreffler, and Elizabeth C Matsui
Picky comprehensively detects high-resolution structural variants in nanopore long reads., Liang Gong, Chee-Hong Wong, Wei-Chung Cheng, Harianto Tjong, Francesca Menghi, Chew Yee Ngan, Edison T Liu, and Chia-Lin Wei
Plain-language medical vocabulary for precision diagnosis., Nicole A Vasilevsky, Erin D Foster, Mark E Engelstad, Leigh Carmody, Matt Might, Chip Chambers, Hugh J S Dawkins, Janine Lewis, Maria G Della Rocca, Michelle Snyder, Cornelius F Boerkoel, Ana Rath, Sharon F Terry, Alastair Kent, Beverly Searle, Gareth Baynam, Erik Jones, Pam Gavin, Michael Bamshad, Jessica Chong, Tudor Groza, David Adams, Adam C Resnick, Allison P Heath, Chris Mungall, Ingrid A Holm, Kayli Rageth, Catherine A Brownstein, Kent Shefchek, Julie A McMurry, Peter N Robinson, Sebastian Köhler, and Melissa A Haendel
PRDM9 and Its Role in Genetic Recombination., Kenneth Paigen and Petko M. Petkov
Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection., Benjamin Y Winer, Elham Shirvani-Dastgerdi, Yaron Bram, Julie Sellau, Benjamin E. Low, Heath Johnson, Tiffany Huang, Gabriela Hrebikova, Brigitte Heller, Yael Sharon, Katja Giersch, Sherif Gerges, Kathleen Seneca, Mihai-Alexandru Pais, Angela S Frankel, Luis Chiriboga, John Cullen, Ronald G Nahass, Marc Lutgehetmann, Jared E Toettcher, Michael V. Wiles, Robert E Schwartz, and Alexander Ploss
Predicting cancer drug targets using genetic networks., Madelyn Adams
Primary hepatic neuroendocrine carcinoma: report of two cases and literature review., Zi-Ming Zhao, Jin Wang, Ugochukwu C Ugwuowo, Liming Wang, and Jeffrey P Townsend
Profiling of epidermal lipids in a mouse model of dermatitis: Identification of potential biomarkers., Jackeline Franco, Christina Ferreira, Tiago J Paschoal Sobreira, John P Sundberg, and Harm HogenEsch
Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza., Jake Dunning, Simon Blankley, Long T Hoang, Mike Cox, Christine M Graham, Philip L James, Chloe I Bloom, Damien Chaussabel, Jacques Banchereau, Stephen J Brett, MOSAIC Investigators, Miriam F Moffatt, Anne O'Garra, and Peter J M Openshaw
Prolonging Reproductive Life after Cancer: The Need for Fertoprotective Therapies., Terri L Woodard and Ewelina Bolcun-Filas
Proteomics and metabolomics for analysis of the dynamics of microbiota., Alex Van Belkum, David Broadwell, Douglas Lovern, Lauren M Petersen, George M. Weinstock, and W Michael Dunne
Quantitative trait mapping in Diversity Outbred mice identifies two genomic regions associated with heart size., John R Shorter, Wei Huang, Ju Youn Beak, Kunjie Hua, Daniel M. Gatti, Fernando Pardo-Manuel de Villena, Daniel Pomp, and Brian C Jensen
RACIPE: a computational tool for modeling gene regulatory circuits using randomization., Bin Huang, Dongya Jia, Jingchen Feng, Herbert Levine, José N Onuchic, and Mingyang Lu
Reconstructing the molecular life history of gliomas., Floris P Barthel, Pieter Wesseling, and Roel G W Verhaak
Regenerative medicine: are we there yet?, Stephen Badylak and Nadia Rosenthal
Relative Contributions of B Cells and Dendritic Cells from Lupus-Prone Mice to CD4, Seung-Chul Choi, Zhiwei Xu, Wei Li, Hong Yang, Derry C. Roopenian, Herbert C Morse, and Laurence Morel
ReprDB and panDB: minimalist databases with maximal microbial representation., Wei Zhou, Nicole R Gay, and Julia Oh
Reproducibility and replicability of rodent phenotyping in preclinical studies., Neri Kafkafi, Joseph Agassi, Elissa J Chesler, John C Crabbe, Wim E Crusio, David Eilam, Robert Gerlai, Ilan Golani, Alex Gomez-Marin, Ruth Heller, Fuad Iraqi, Iman Jaljuli, Natasha A Karp, Hugh Morgan, George Nicholson, Donald W Pfaff, S Helene Richter, Philip B Stark, Oliver Stiedl, Victoria Stodden, Lisa M Tarantino, Valter Tucci, William Valdar, Robert W Williams, Hanno Würbel, and Yoav Benjamini
Reproduction: Oocytes Call, Granulosa Cells Connect., John J. Eppig
Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects., Simona Volpi, Carol J Bult, Rex L Chisholm, Patricia A Deverka, Geoffrey S Ginsburg, Howard J Jacob, Melpomeni Kasapi, Howard L McLeod, Dan M Roden, Marc S Williams, Eric D Green, Laura Lyman Rodriguez, Samuel Aronson, Larisa H Cavallari, Joshua C Denny, Lynn G Dressler, Julie A Johnson, Teri E Klein, J Steven Leeder, Micheline Piquette-Miller, Minoli Perera, Laura J Rasmussen-Torvik, Heidi L Rehm, Marylyn D Ritchie, Todd C Skaar, Nikhil Wagle, Richard Weinshilboum, Kristin W Weitzel, Robert Wildin, John Wilson, Teri A Manolio, and Mary V Relling
Research in Action: effectively communicating our translational impact on the JAX.org public website., Grace Niewijk
Resident risks., Michelle Spoto and Julia Oh
Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo"., Lauryl M J Nutter, Jason D Heaney, K C Kent Lloyd, Stephen A. Murray, John R Seavitt, William C Skarnes, Lydia Teboul, Steve D M Brown, and Mark Moore
Restoration of vision after de novo genesis of rod photoreceptors in mammalian retinas., Kai Yao, Suo Qiu, Yanbin V Wang, Silvia J H Park, Ethan J Mohns, Bhupesh Mehta, Xinran Liu, Bo Chang, David Zenisek, Michael C Crair, Jonathan B Demb, and Bo Chen
RHBDF2-regulated growth factor signaling in a rare human disease tylosis with esophageal cancer: What can we learn from murine models?, Vishnu Hosur, Benjamin E. Low, Michelle L Farley, Lisa M. Burzenski, Leonard D. Shultz, and Michael V. Wiles
ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm., Russell A Gould, Hamza Aziz, Courtney E Woods, Manuel Alejandro Seman-Senderos, Elizabeth Sparks, Christoph Preuss, Florian Wünnemann, Djahida Bedja, Cassandra R Moats, Sarah A McClymont, Rebecca Rose, Nara Sobreira, Hua Ling, Gretchen MacCarrick, Ajay Anand Kumar, Ilse Luyckx, Elyssa Cannaerts, Aline Verstraeten, Hanna M Björk, Ann-Cathrin Lehsau, Vinod Jaskula-Ranga, Henrik Lauridsen, Asad A Shah, Christopher L Bennett, Patrick T Ellinor, Honghuang Lin, Eric M Isselbacher, Christian Lacks Lino Cardenas, Jonathan T Butcher, G Chad Hughes, Mark E Lindsay, Luc Mertens, Anders Franco-Cereceda, Judith M A Verhagen, Marja Wessels, Salah A Mohamed, Per Eriksson, Seema Mital, Lut Van Laer, Bart L Loeys, Gregor Andelfinger, Andrew S McCallion, and Harry C Dietz
Role of Alström syndrome 1 in the regulation of blood pressure and renal function., Ankita Bachhawat Jaykumar, Paulo S Caceres, Keyona N King-Medina, Tang-Dong Liao, Indrani Datta, Dipak Maskey, Juergen K. Naggert, Mariela Mendez, William H Beierwaltes, and Pablo A Ortiz
Role of metabolic spatiotemporal dynamics in regulating biofilm colony expansion., Federico Bocci, Yoko Suzuki, Mingyang Lu, and José N Onuchic
Role of noise and parametric variation in the dynamics of gene regulatory circuits., Vivek Kohar and Mingyang Lu
Role of PRDM9 KRAB domain in H3K4 trimethylation at hotspot loci., Naomi Bronkema
Role of TGF-β in Self-Peptide Regulation of Autoimmunity., Bhagirath Singh, Michael D Krawetz, Rachel M De Lima, Rinee Mukherjee, Pratibha Chaturvedi, Edwin Lee-Chan, Edward H. Leiter, and Kelly L Summers
SARNAclust: Semi-automatic detection of RNA protein binding motifs from immunoprecipitation data., Ivan Dotu, Scott I Adamson, Benjamin Coleman, Cyril Fournier, Emma Ricart-Altimiras, Eduardo Eyras, and Jeffrey H Chuang
Screening Gene Knockout Mice for Variation in Bone Mass: Analysis by μCT and Histomorphometry., David W Rowe, Douglas J Adams, Seung-Hyun Hong, Caibin Zhang, Dong-Guk Shin, C Renata Rydzik, Li Chen, Zhihua Wu, Gaven Garland, Dana A Godfrey, John P Sundberg, and Cheryl Ackert-Bicknell
Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia., John P Sundberg, Tong Shen, Oliver Fiehn, Robert H Rice, Kathleen A Silva, Victoria E. Kennedy, Nicholas E Gott, Louise A. Dionne, Lesley S Bechtold, Stephen A. Murray, Raoul Kuiper, and C Herbert Pratt
Sensing the cilium, digital capture of ciliary data for comparative genomics investigations., Karen R. Christie and Judith A. Blake
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls., Jason Flannick, Michael L. Stitzel, and et al
Serial immunological parameters in a phase II trial of exemestane and low-dose oral cyclophosphamide in advanced hormone receptor-positive breast cancer., Maryann Kwa, Xiaochun Li, Yelena Novik, Ruth Oratz, Komal Jhaveri, Jennifer Wu, Ping Gu, Marleen Meyers, Franco Muggia, James Speyer, Alyssa Iwano, Maryam Bonakdar, Lina Kozhaya, Ece Tavukcuoglu, Bahar Budan, Roy Raad, Judith D Goldberg, Derya Unutmaz, and Sylvia Adams
Severity of Disease in Humanized Mice Infected With Ebola Virus or Reston Virus Is Associated With Magnitude of Early Viral Replication in Liver., Jessica R Spengler, Greg Saturday, Kerry J Lavender, Cynthia Martellaro, James G. Keck, Stuart T Nichol, Christina F Spiropoulou, Heinz Feldmann, and Joseph Prescott
Sex- and Strain-related Differences in the Stress Response of Mice to CO₂ Euthanasia., Michelle A Creamer-Hente, Fironica K Lao, Zala P Dragos, and Linda L Waterman
Shared and organism-specific host responses to childhood diarrheal diseases revealed by whole blood transcript profiling., Hannah A DeBerg, Mussaret B Zaidi, Matthew C Altman, Prasong Khaenam, Vivian H Gersuk, Freddy D Campos, Iza Perez-Martinez, Mario Meza-Segura, Damien Chaussabel, Jacques Banchereau, Teresa Estrada-Garcia, and Peter S Linsley
Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication in the Mouse Heart., Daniel A Skelly, Galen T Squiers, Michael A McLellan, Mohan T Bolisetty, Paul Robson, Nadia A Rosenthal, and Alexander R Pinto
Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes., Bruce A Rheaume, Amyeo Jereen, Mohan Bolisetty, Muhammad S Sajid, Yue Yang, Kathleen Renna, Lili Sun, Paul Robson, and Ephraim F Trakhtenberg
Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci., Jingtao Lilue, Anthony G Doran, Ian T Fiddes, Monica Abrudan, Joel Armstrong, Ruth Bennett, William Chow, Joanna Collins, Stephan Collins, Anne M Czechanski, Petr Danecek, Mark Diekhans, Dirk-Dominik Dolle, Matt Dunn, Richard Durbin, Dent Earl, Anne Ferguson-Smith, Paul Flicek, Jonathan Flint, Adam Frankish, Beiyuan Fu, Mark Gerstein, James Gilbert, Leo Goodstadt, Jennifer Harrow, Kerstin Howe, Ximena Ibarra-Soria, Mikhail Kolmogorov, Chris J Lelliott, Darren W Logan, Jane Loveland, Clayton E Mathews, Richard Mott, Paul Muir, Stefanie Nachtweide, Fabio C P Navarro, Duncan T Odom, Naomi Park, Sarah Pelan, Son K Pham, Mike Quail, Laura Reinholdt, Lars Romoth, Lesley Shirley, Cristina Sisu, Marcela Sjoberg-Herrera, Mario Stanke, Charles Steward, Mark Thomas, Glen Threadgold, David Thybert, James Torrance, Kim Wong, Jonathan Wood, Binnaz Yalcin, Fengtang Yang, David J Adams, Benedict Paten, and Thomas M Keane
Snell Nobel Document (left page), George Davis Snell
Snell Nobel Document (right page), George Davis Snell
Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia., Valentina Cerrato, Sara Mercurio, Ketty Leto, Elisa Fucà, Eriola Hoxha, Sara Bottes, Miriam Pagin, Marco Milanese, Chew Yee Ngan, Giulia Concina, Sergio Ottolenghi, Chia-Lin Wei, Giambattista Bonanno, Giulio Pavesi, Filippo Tempia, Annalisa Buffo, and Silvia K Nicolis
Spermatogonial stem cell self-renewal in the mouse, Danielle Smith
Spontaneous Posterior Segment Vascular Disease Phenotype of a Mouse Model, rnv3, Is Dependent on the Crb1rd8 Allele., Bo Chang, Bernie Fitzmaurice, Jieping Wang, Benjamin E. Low, Michael V. Wiles, and Patsy M. Nishina
Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice., Yunsik Choi, Sanghyuk Lee, Kapyoul Kim, Soo-Hyun Kim, Yeun-Jun Chung, and Charles Lee
Sympathetic innervation of the developing aqueous humor drainage structures., Haelynn Gim
Synthetic Peptide CK2.3 Enhances Bone Mineral Density in Senile Mice., John Nguyen, Hilary Weidner, Lora M Schell, Linda Sequeira, Ryan Kabrick, Saurabh Dharmadhikari, Harold Coombs, Randall L Duncan, Liyun Wang, and Anja Nohe
Systematic analysis of copy number variation associated with congenital diaphragmatic hernia., Qihui Zhu, Frances A High, Chengsheng Zhang, Eliza Cerveira, Meaghan K Russell, Mauro Longoni, Maliackal P Joy, Mallory Ryan, Adam Mil-Homens, Lauren Bellfy, Caroline M Coletti, Pooja Bhayani, Regis Hila, Jay M Wilson, Patricia K Donahoe, and Charles Lee
T-Cell-Intrinsic Receptor Interacting Protein 2 Regulates Pathogenic T Helper 17 Cell Differentiation., Kenichi Shimada, Rebecca A Porritt, Janet L Markman, Jacqueline Gire O'Rourke, Daiko Wakita, Magali Noval Rivas, Chihiro Ogawa, Lina Kozhaya, Gislâine A Martins, Derya Unutmaz, Robert H Baloh, Timothy R Crother, Shuang Chen, and Moshe Arditi
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis., Pilar M Dominguez, Hussein Ghamlouch, Wojciech Rosikiewicz, Parveen Kumar, Wendy Béguelin, Lorena Fontán, Martín A Rivas, Patrycja Pawlikowska, Marine Armand, Enguerran Mouly, Miguel Torres-Martin, Ashley S Doane, María T Calvo Fernandez, Matt Durant, Veronique Della-Valle, Matt Teater, Luisa Cimmino, Nathalie Droin, Saber Tadros, Samaneh Motanagh, Alan H Shih, Mark A Rubin, Wayne Tam, Iannis Aifantis, Ross L Levine, Olivier Elemento, Giorgio Inghirami, Michael R Green, Maria E Figueroa, Olivier A Bernard, Said Aoufouchi, Sheng Li, Rita Shaknovich, and Ari M Melnick
The adaptive immune response to cardiac injury-the true roadblock to effective regenerative therapies?, Susanne Sattler, Paul Fairchild, Fiona M Watt, Nadia Rosenthal, and Sian E Harding
The "adipose tissue expandability" hypothesis: a potential mechanism for insulin resistance in obese youth., Sonia Caprio, Bridget Pierpont, and Romy Kursawe
The Energetics and Physiological Impact of Cohesin Extrusion., Laura Vian, Aleksandra Pękowska, Suhas S P Rao, Kyong-Rim Kieffer-Kwon, Seolkyoung Jung, Laura Baranello, Su-Chen Huang, Laila El Khattabi, Marei Dose, Nathanael Pruett, Adrian L Sanborn, Andres Canela, Yaakov Maman, Anna Oksanen, Wolfgang Resch, Xingwang Li, Byoungkoo Lee, Alexander L Kovalchuk, Zhonghui Tang, Steevenson Nelson, Michele Di Pierro, Ryan R Cheng, Ido Machol, Brian Glenn St Hilaire, Neva C Durand, Muhammad S Shamim, Elena K Stamenova, José N Onuchic, Yijun Ruan, Andre Nussenzweig, David Levens, Erez Lieberman Aiden, and Rafael Casellas
The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection., Andrea M Muscat, Nicholas C Wong, Katharine J Drummond, Elizabeth M Algar, Mustafa Khasraw, Roel G W Verhaak, Kathryn Field, Mark A Rosenthal, and David M Ashley
The Genetic Landscape of Hypoplastic Left Heart Syndrome., Hisato Yagi, Xiaoqin Liu, George C Gabriel, Yijen Wu, Kevin A Peterson, Stephen A. Murray, Bruce J Aronow, Lisa J Martin, D Woodrow Benson, and Cecilia W Lo
The genetic mechanism driving risk taking phenotype in BXD recombinant inbred panel., Sartre K. Ndebaneza
The HDAC3-SMARCA4-miR-27a axis promotes expression of the, Narendra Bharathy, Noah E Berlow, Eric Wang, Jinu Abraham, Teagan P Settelmeyer, Jody E Hooper, Matthew N Svalina, Yoshihiro Ishikawa, Keith Zientek, Zia Bajwa, Martin W Goros, Brian S Hernandez, Johannes E Wolff, Michelle A Rudek, Linping Xu, Nicole M Anders, Ranadip Pal, Alexandria P Harrold, Angela M Davies, Arya Ashok, Darnell Bushby, Maria Mancini, Christopher Noakes, Neal C Goodwin, Peter Ordentlich, James G. Keck, Douglas S Hawkins, Erin R Rudzinski, Bishwanath Chatterjee, Hans Peter Bächinger, Frederic G Barr, Jennifer Liddle, Benjamin A Garcia, Atiya Mansoor, Theodore J Perkins, Christopher R Vakoc, Joel E Michalek, and Charles Keller
The Impact of Adherens and Tight Junctions on Physiological Function and Pathological Changes in the Retina., Yang Kong, Juergen K. Naggert, and Patsy M. Nishina
The innate immune response to ischemic injury: a multiscale modeling perspective., Elena Dimitrova, Leslie A Caromile, Reinhard Laubenbacher, and Linda H Shapiro
The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation., Violeta Muñoz-Fuentes, Pilar Cacheiro, Terrence F Meehan, Juan Antonio Aguilar-Pimentel, Steve D M Brown, Ann M Flenniken, Paul Flicek, Antonella Galli, Hamed Haseli Mashhadi, Martin Hrabě de Angelis, Jong Kyoung Kim, K C Kent Lloyd, Colin McKerlie, Hugh Morgan, Stephen A. Murray, Lauryl M J Nutter, Patrick T Reilly, John R Seavitt, Je Kyung Seong, Michelle Simon, Hannah Wardle-Jones, Ann-Marie Mallon, Damian Smedley, and Helen E Parkinson
The interstitium in cardiac repair: role of the immune-stromal cell interplay., Elvira Forte, Milena B Furtado, and Nadia Rosenthal
The Macrophage in Cardiac Homeostasis and Disease: JACC Macrophage in CVD Series (Part 4)., Kory J Lavine, Alexander R Pinto, Slava Epelman, Benjamin J Kopecky, Xavier Clemente-Casares, James Godwin, Nadia Rosenthal, and Jason C Kovacic
The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells., Jianwen Dong, Soon Young Park, Nghi Nguyen, Ravesanker Ezhilarasan, Emmanuel Martinez-Ledesma, Shaofang Wu, Verlene Henry, Yuji Piao, Ningyi Tiao, David Brunell, Clifford Stephan, Roel G W Verhaak, Erik Sulman, Veerakumar Balasubramaniyan, and John F de Groot
The Role of Ceramide Synthases in the Pathogenicity of Cryptococcus neoformans., Mansa A Munshi, Justin M Gardin, Ashutosh Singh, Chiara Luberto, Robert Rieger, Tejas Bouklas, Bettina C Fries, and Maurizio Del Poeta
The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations., Francesca Menghi, Floris P Barthel, Vinod Yadav, Ming Tang, Bo Ji, Zhonghui Tang, Gregory W. Carter, Yijun Ruan, Ralph Scully, Roel G W Verhaak, Jos Jonkers, and Edison T Liu
Towards smart self-clearing glaucoma drainage device., Hyunsu Park, Amir Hossein Rafiee, Simon W M John, Arezoo M. Ardekani, and Hyowon Lee
Training mouse pathologists: 16th annual workshop on the pathology of mouse models of human disease., John P Sundberg, Kelli Boyd, Harm Hogenesch, Alexander Yu Nikitin, Piper M Treuting, and Jerrold M Ward
Transcriptional profiling of murine osteoblast differentiation based on RNA-seq expression analyses., Layal Abo Khayal, Johannes Grünhagen, Ivo Provazník, Stefan Mundlos, Uwe Kornak, Peter N Robinson, and Claus-Eric Ott
Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies., Lori L O'Brien, Qiuyu Guo, Emad Bahrami-Samani, Joo-Seop Park, Sean M Hasso, Young-Jin Lee, Alan Fang, Albert D Kim, Jinjin Guo, Trudy M Hong, Kevin A Peterson, Scott Lozanoff, Ramya Raviram, Bing Ren, Ben Fogelgren, Andrew D Smith, Anton Valouev, and Andrew P McMahon
Translational vision research models program., Jungyeon Won, Lan Ying Shi, Wanda L. Hicks, Jieping Wang, Juergen K. Naggert, and Patsy M. Nishina
Triple Vectors Expand AAV Transfer Capacity in the Retina., Andrea Maddalena, Patrizia Tornabene, Paola Tiberi, Renato Minopoli, Anna Manfredi, Margherita Mutarelli, Settimio Rossi, Francesca Simonelli, Juergen K. Naggert, Davide Cacchiarelli, and Alberto Auricchio
TumorFusions: an integrative resource for cancer-associated transcript fusions., Xin Hu, Qianghu Wang, Ming Tang, Floris P Barthel, Samirkumar B Amin, Kosuke Yoshihara, Frederick M Lang, Emmanuel Martinez-Ledesma, Soo Hyun Lee, Siyuan Zheng, and Roel G W Verhaak
Tuning of human MAIT cell activation by commensal bacteria species and MR1-dependent T-cell presentation., Cihan Tastan, Ece Karhan, Wei Zhou, Elizabeth Fleming, Anita Y Voigt, Xudong Yao, Lei Wang, Meghan Horne, Lindsey Placek, Lina Kozhaya, Julia Oh, and Derya Unutmaz
Two-phase differential expression analysis for single cell RNA-seq., Zhijin Wu, Yi Zhang, Michael L. Stitzel, and Hao Wu
Type 2 Diabetes-Associated Genetic Variants Regulate Chromatin Accessibility in Human Islets., Shubham Khetan, Romy Kursawe, Ahrim Youn, Nathan Lawlor, Alexandria Jillette, Eladio J Marquez, Duygu Ucar, and Michael L. Stitzel
Unbiased profiling of the origin and function of cardiac interstitial cells, Kaesi Morelli
Understanding chemotherapeutic-gene relationships through cross-species analysis., Akeena Harper
Understanding the relationship between neuroinflammatory cells and AD-related symptoms through systems genetics., Michelle Kung
Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome"., John C Schimenti and Mary Ann Handel
Using gene network analysis to identify novel candidate genes for Congenital Diaphragmatic Hernia (CDH)., Taylar J. Mouton
Viable Mice with Extensive Gene Humanization (25-kbp) Created Using Embryonic Stem Cell/Blastocyst and CRISPR/Zygote Injection Approaches., Tiffany Leidy-Davis, Kai Cheng, Leslie Goodwin, Judith L Morgan, Wen Chun Juan, Xavier Roca, S Tiong Ong, and David E. Bergstrom
Whole-exome sequencing capture kit biases yield false negative mutation calls in TCGA cohorts., Victor G Wang, Hyunsoo Kim, and Jeffrey Chuang
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes., Marcela Brissova, Rachana Haliyur, Diane Saunders, Shristi Shrestha, Chunhua Dai, David M Blodgett, Rita Bottino, Martha Campbell-Thompson, Radhika Aramandla, Gregory Poffenberger, Jill Lindner, Fong Cheng Pan, Matthias G von Herrath, Dale L Greiner, Leonard D. Shultz, May Sanyoura, Louis H Philipson, Mark Atkinson, David M Harlan, Shawn E Levy, Nripesh Prasad, Roland Stein, and Alvin C Powers