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    Content Posted in 2023

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    3D-bioprinting of patient-derived cardiac tissue models for studying congenital heart disease., Jayne T Wolfe, Wei He, Min-Su Kim, Huan-Ling Liang, Akankshya Shradhanjali, Hilda Jurkiewicz, Bonnie P Freudinger, Andrew S Greene, John F LaDisa, Lobat Tayebi, Michael E Mitchell, Aoy Tomita-Mitchell, and Brandon J Tefft

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    3D-Epigenomic Regulation of Gene Transcription in Hepatocellular Carcinoma., Yuliang Feng, Ping Wang, Liuyang Cai, Meixiao Zhan, Fan He, Jiahui Wang, Yong Li, Eva Gega, Wei Zhang, Wei Zhao, Yongjie Xin, Xudong Chen, Yijun Ruan, and Ligong Lu

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    ACDA: implementation of an augmented drug synergy prediction algorithm., Sergii Domanskyi, Emily L Jocoy, Anuj Srivastava, and Carol J Bult

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    A comparison of DNA sequencing and gene expression profiling to assist tissue of origin diagnosis in cancer of unknown primary., Atara Posner, Owen Wj Prall, Tharani Sivakumaran, Dariush Etemadamoghadam, Niko Thio, Andrew Pattison, Shiva Balachander, Krista Fisher, Samantha Webb, Colin Wood, Anna DeFazio, Nicholas Wilcken, Bo Gao, Christos S Karapetis, Madhu Singh, Ian M Collins, Gary Richardson, Christopher Steer, Mark Warren, Narayan Karanth, Gavin Wright, Scott Williams, Joshy George, Rodney J Hicks, Alex Boussioutas, Anthony J Gill, Benjamin J Solomon, Huiling Xu, Andrew Fellowes, Stephen B Fox, Penelope Schofield, David Bowtell, Linda Mileshkin, and Richard W Tothill

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    Acute Myeloid Leukemia Causes T Cell Exhaustion and Depletion in a Humanized Graft-versus-Leukemia Model., Bei Jia, Chenchen Zhao, Kentaro Minagawa, Hiroko Shike, David F Claxton, W Christopher Ehmann, Witold B Rybka, Shin Mineishi, Ming Wang, Todd D Schell, K Sandeep Prabhu, Robert F Paulson, Yi Zhang, Leonard D. Shultz, and Hong Zheng

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    Adaptive Sentinel Testing in Workplace for COVID-19 Pandemic., Yi Li, Mandy Chen, Joshy George, Edison Liu, and Radha Krishna Murthy Karuturi

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    A data-driven optimization method for coarse-graining gene regulatory networks., Cristian Caranica and Mingyang Lu

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    Adding gene transcripts into genomic prediction improves accuracy and reveals sampling time dependence., Bruno C Perez, Marco C A M Bink, Karen L. Svenson, Gary Churchill, and Mario P L Calus

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    A developmental approach to diversifying neuroscience through effective mentorship practices: perspectives on cross-identity mentorship and a critical call to action., Tanisha G Hill-Jarrett, Rowena Ng, Carlos Cardenas-Iniguez, Jemima Akinsanya, Ismary Blanco, Johnathan M Borland, James S Brown, Tameka Clemons, Adriana K Cushnie, Jacqueline Garcia, Brianna George, Cera W Hassinan, Timothy J Hines, Dan Landayan, Taylor A McCorkle, Katherine R Meckel, Mariajose Metcalfe, Samantha A Montoya, Deborah K Rose, and Desmond R Warren

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    A Dpagt1 Missense Variant Causes Degenerative Retinopathy without Myasthenic Syndrome in Mice, Lillian F Hyde, Yang Kong, Lihong Zhao, Sriganesh Ramachandra Rao, Jieping Wang, Lisa Stone, Andrew Njaa, Gayle B. Collin, Mark P. Krebs, Bo Chang, Steven J Fliesler, Patsy M. Nishina, and Juergen K. Naggert

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    Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)., Sanjay Jain, Liming Pei, Jeffrey M Spraggins, Michael Angelo, James P Carson, Nils Gehlenborg, Fiona Ginty, Joana P Gonçalves, James S Hagood, John W Hickey, Neil L Kelleher, Louise C Laurent, Shin Lin, Yiing Lin, Huiping Liu, Alexandra Naba, Ernesto S Nakayasu, Wei-Jun Qian, Andrea Radtke, Paul Robson, Brent R Stockwell, Raf Van de Plas, Ioannis S Vlachos, Mowei Zhou, Katy Börner, and Michael P Snyder

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    Advances in Animal Models and Cutting-Edge Research in Alternatives: Proceedings of the Third International Conference on 3Rs Research and Progress, Vishakhapatnam, 2022., Nikita Narayan Naik, Bharadwaja Vadloori, Suresh Poosala, Pratima Srivastava, Sandra Coecke, Adrian Smith, Aysha Akhtar, Clive Roper, Sridhar Radhakrishnan, Balaji Bhyravbhatla, Madhujit Damle, Venkat Koushik Pulla, Johannes Hackethal, Reyk Horland, Albert P Li, Falguni Pati, Manu Smriti Singh, Paola Occhetta, Rohit Bisht, Prajakta Dandekar, Krishna Bhagavatula, Dasja Pajkrt, Michael Johnson, Tilo Weber, John Huang, Lisiena Hysenaj, Banerjee Mallar, Bhat Ramray, Santosh Dixit, Shreekanth Joshi, and Mandar Kulkarni

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    Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium., Adriana Fonseca, João Lobo, Florette K Hazard, Joanna J Gell, Peter K Nicholls, Robert S Weiss, Lindsay Klosterkemper, Samuel L Volchenboum, James C Nicholson, A Lindsay Frazier, James F Amatruda, Aditya Bagrodia, Michelle Lockley, and Matthew J Murray

     

    Advancing Metabolic Flux Analysis in the Single-Cell Era, Maggi Smart

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    Africa-specific human genetic variation near CHD1L associates with HIV-1 load., Paul J McLaren, Immacolata Porreca, Gennaro Iaconis, Hoi Ping Mok, Subhankar Mukhopadhyay, Emre Karakoc, Sara Cristinelli, Cristina Pomilla, István Bartha, Christian W Thorball, Riley H Tough, Paolo Angelino, Cher S Kiar, Tommy Carstensen, Segun Fatumo, Tarryn Porter, Isobel Jarvis, William C Skarnes, Andrew Bassett, Marianne K DeGorter, Mohana Prasad Sathya Moorthy, Jeffrey F Tuff, Eun-Young Kim, Miriam Walter, Lacy M Simons, Arman Bashirova, Susan Buchbinder, Mary Carrington, Andrea Cossarizza, Andrea De Luca, James J Goedert, David B Goldstein, David W Haas, Joshua T Herbeck, Eric O Johnson, Pontiano Kaleebu, William Kilembe, Gregory D Kirk, Neeltje A Kootstra, Alex H Kral, Olivier Lambotte, Ma Luo, Simon Mallal, Javier Martinez-Picado, Laurence Meyer, José M Miro, Pravi Moodley, Ayesha A Motala, James I Mullins, Kireem Nam, Niels Obel, Fraser Pirie, Francis A Plummer, Guido Poli, Matthew A Price, Andri Rauch, Ioannis Theodorou, Alexandra Trkola, Bruce D Walker, Cheryl A Winkler, Jean-François Zagury, Stephen B Montgomery, Angela Ciuffi, Judd F Hultquist, Steven M Wolinsky, Gordon Dougan, Andrew M L Lever, Deepti Gurdasani, Harriet Groom, Manjinder S Sandhu, and Jacques Fellay

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    A genetic locus complements resistance to Bordetella pertussis-induced histamine sensitization., Abbas Raza, Sean A Diehl, Dimitry N Krementsov, Laure K Case, Dawei Li, Jason Kost, Robyn L Ball, Elissa J Chesler, Vivek M. Philip, Rui Huang, Yan Chen, Runlin Ma, Anna L Tyler, J Matthew Mahoney, Elizabeth P Blankenhorn, and Cory Teuscher

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    A genome-wide CRISPR activation screen identifies, Dinesh B Uthaya Kumar, Marina Yurieva, Jessica D S Grassmann, Lina Kozhaya, Caleb Dante McBride, Derya Unutmaz, and Adam Williams

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    A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non-Small Cell Lung Cancer., Xing Yi Woo, Anuj Srivastava, Philip C Mack, Joel H. Graber, Brian J Sanderson, Michael W Lloyd, Mandy Chen, Sergii Domanskyi, Regina Gandour-Edwards, Rebekah A Tsai, James G. Keck, Mingshan Cheng, Margaret Bundy, Emily L Jocoy, Jonathan W Riess, William Holland, Stephen C. Grubb, James G Peterson, Grace Stafford, Carolyn Paisie, Steven Neuhauser, Radha Krishna Murthy Karuturi, Joshy George, Allen K. Simons, Margaret Chavaree, Clifford G Tepper, Neal Goodwin, Susan Airhart, Primo N Lara, Thomas H Openshaw, Edison Liu, David R Gandara, and Carol J Bult

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    Age-related changes to adipose tissue and peripheral neuropathy in genetically diverse HET3 mice differ by sex and are not mitigated by rapamycin longevity treatment., Jake W Willows, Morganne Robinson, Zahra Alshahal, Samantha K Morrison, Gargi Mishra, Harrison Cyr, Magdalena Blaszkiewicz, Gilian Gunsch, Sabrina DiPietro, Emma Paradie, Benjamin Tero, Anne Harrington, Larisa Ryzhova, Lucy Liaw, Peter C. Reifsnyder, David E Harrison, and Kristy L Townsend

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    A-Kinase Anchor Protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury., Ramani Soundararajan, Helena Hernández-Cuervo, Timothy M Stearns, Anthony J Griswold, Sahebgowda Sidramagowda Patil, Jutaro Fukumoto, Venkata Ramireddy Narala, Lakshmi Galam, Richard Lockey, and Narasaiah Kolliputi

     

    A machine-vision-based frailty index for mice., Leinani E. Hession, Gautam S Sabnis, Gary Churchill, and Vivek Kumar

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    A method for comparing multiple imputation techniques: A case study on the U.S. national COVID cohort collaborative., Elena Casiraghi, Rachel Wong, Margaret Hall, Ben D Coleman, Marco Notaro, Michael D Evans, Jena S Tronieri, Hannah Blau, Bryan Laraway, Tiffany J Callahan, Lauren E Chan, Carolyn T Bramante, John B Buse, Richard A Moffitt, Til Stürmer, Steven G Johnson, Yu Raymond Shao, Justin Reese, Peter N Robinson, Alberto Paccanaro, Giorgio Valentini, Jared D Huling, and Kenneth J Wilkins

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    A microbiome-dependent gut-brain pathway regulates motivation for exercise., Lenka Dohnalová, Patrick Lundgren, Jamie R E Carty, Nitsan Goldstein, Sebastian L Wenski, Pakjira Nanudorn, Sirinthra Thiengmag, Kuei-Pin Huang, Lev Litichevskiy, Hélène C Descamps, Karthikeyani Chellappa, Ana Glassman, Susanne Kessler, Jihee Kim, Timothy O Cox, Oxana Dmitrieva-Posocco, Andrea C Wong, Erik L Allman, Soumita Ghosh, Nitika Sharma, Kasturi Sengupta, Belinda Cornes, Nitai Dean, Gary Churchill, Tejvir S Khurana, Mark A Sellmyer, Garret A FitzGerald, Andrew D Patterson, Joseph A Baur, Amber L Alhadeff, Eric J N Helfrich, Maayan Levy, J Nicholas Betley, and Christoph A Thaiss

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    A mouse model of cone photoreceptor function loss, Anna S E N Naggert, Gayle B. Collin, Jieping Wang, Mark P. Krebs, and Bo Chang

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    A multi-lab experimental assessment reveals that replicability can be improved by using empirical estimates of genotype-by-lab interaction., Iman Jaljuli, Neri Kafkafi, Eliezer Giladi, Ilan Golani, Illana Gozes, Elissa J Chesler, Molly A. Bogue, and Yoav Benjamini

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    An allelic series of spontaneous Rorb mutant mice exhibit a gait phenotype, changes in retina morphology and behavior, and gene expression signatures associated with the unfolded protein response., George Murray, Jason A. Bubier, Oraya Zinder, Belinda S. Harris, James Clark, Mia-Cara Christopher, Courtany Hanley, Harianto Tjong, Meihong Li, Chew Yee Ngan, Laura G Reinholdt, Robert W. Burgess, and Abigail L D Tadenev

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    Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes., Kendall Higgins, Bret A Moore, Zorana Berberovic, Hibret A Adissu, Mohammad Eskandarian, Ann M Flenniken, Andy Shao, Denise M Imai, Dave Clary, Louise Lanoue, Susan Newbigging, Lauryl M J Nutter, David J Adams, Fatima Bosch, Robert Schneider, Steve D M Brown, Mary E Dickinson, Michael Dobbie, Paul Flicek, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D Heaney, Yann Herault, Martin Hrabe de Angelis, Hsian-Jean Genie Chin, Fabio Mammano, Chuan Qin, Toshihiko Shiroishi, Radislav Sedlacek, J-K Seong, Ying Xu, K C Kent Lloyd, Colin McKerlie, and Ala Moshiri

     

    Analysis of the interaction of genetic background with DYRK1a inhibition on the proliferation and differentiation of mouse embryonic stem cell-derived Neural Precursor Cell, Nicole Da Costa

     

    Analyzing C12orf65 (MTRFR) Expression in Mutant Mouse Models, Jupiter Kalinowski

     

    An Analysis of the Features and Dynamics of BRCA1 Promoter Methylation in Triple Negative Breast and Ovarian cancer, Angela Zhu

     

    An approach to promoting survival of human microglia in humanized mouse models of Alzheimer's Disease, Lauren Baptiste

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    An ethical framework for human embryology with embryo models., Nicolas C Rivron, Alfonso Martinez Arias, Martin Pera, Naomi Moris, and Hafez Ismaili M'hamdi

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    A new fasciocutaneous flap model identifies a critical role for endothelial Notch signaling in wound healing and flap survival., Khaled Dastagir, Jaba Gamrekelashvili, Nadjib Dastagir, Anne Limbourg, Dustin Kijas, Tamar Kapanadze, Peter M Vogt, and Florian P Limbourg

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    A New Standardized Clinical Model for Evaluation of Nerve Guides: A Single-Blinded Randomized Controlled Prospective Study., Khaled Dastagir, Christine Radtke, Nadjib Dastagir, Vesna Bucan, Sarah Strauß, Andreas Jokuszies, and Peter Maria Vogt

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    An expectation-maximization framework for comprehensive prediction of isoform-specific functions., Guy Karlebach, Leigh Carmody, Jagadish Chandrabose Sundaramurthi, Elena Casiraghi, Peter Hansen, Justin Reese, Christopher J Mungall, Giorgio Valentini, and Peter N Robinson

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    Animals, quality and the pursuit of relevance., Karen L. Svenson, Stephen D Krasinski, Michael Ellis, Nadia Rosenthal, Edison Liu, and Kenneth H Fasman

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    An integrated tumor, immune and microbiome atlas of colon cancer., Jessica Roelands, Peter J K Kuppen, Eiman I Ahmed, Raghvendra Mall, Tariq Masoodi, Parul Singh, Gianni Monaco, Christophe Raynaud, Noel F C C de Miranda, Luigi Ferraro, Tatiana C Carneiro-Lobo, Najeeb Syed, Arun Rawat, Amany Awad, Julie Decock, William Mifsud, Lance D Miller, Shimaa Sherif, Mahmoud G Mohamed, Darawan Rinchai, Marc Van den Eynde, Rosalyn W Sayaman, Elad Ziv, Francois Bertucci, Mahir Abdulla Petkar, Stephan Lorenz, Lisa Sara Mathew, Kun Wang, Selvasankar Murugesan, Damien Chaussabel, Alexander L Vahrmeijer, Ena Wang, Anna Ceccarelli, Khalid A Fakhro, Gabriele Zoppoli, Alberto Ballestrero, Rob A E M Tollenaar, Francesco M Marincola, Jérôme Galon, Souhaila Al Khodor, Michele Ceccarelli, Wouter Hendrickx, and Davide Bedognetti

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    An integrative approach for exploring the nature of fibroepithelial neoplasms., Jihui Yun, Woohang Heo, Eun-Shin Lee, Deukchae Na, Wonyoung Kang, Jinjoo Kang, Jeesoo Chae, Dakyung Lee, Woochan Lee, Jinha Hwang, Tae-Kyung Yoo, Bok Sil Hong, Hye-Youn Son, Dong-Young Noh, Charles Lee, Hyeong-Gon Moon, and Jong-Il Kim

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    A Novel ENU-Induced, Timothy J Hines, Janice Bailey, Hedi Liu, Anyonya R Guntur, Kevin L. Seburn, Samia L Pratt, Jonathan R Funke, Lisa M Tarantino, and Robert W. Burgess

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    A novel HSPB1S139F mouse model of Charcot-Marie-Tooth Disease, Keila S Espinoza, Kyra N Hermanson, Cameron A Beard, Nicholas U Schwartz, Justin M Snider, Benjamin E. Low, Michael V. Wiles, Yusuf A Hannun, Lina M Obeid, and Ashley J Snider

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    A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice., Susan Barendrecht, An Schreurs, Stefanie Geissler, Victor Sabanov, Victoria Ilse, Vera Rieckmann, Rico Eichentopf, Anja Künemund, Benjamin Hietel, Sebastian Wussow, Katrin Hoffmann, Kerstin Körber-Ferl, Ravi S Pandey, Gregory W. Carter, Hans-Ulrich Demuth, Max Holzer, Steffen Roßner, Stephan Schilling, Christoph Preuss, Detlef Balschun, and Holger Cynis

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    Aon: a service to augment Alliance Genome Resource data with additional species., Sophie K Kearney, Alexander Berger, and Erich Baker

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    A path to translation: How 3D patient tumor avatars enable next generation precision oncology., Shree Bose, Margarida Barroso, Milan G Chheda, Hans Clevers, Elena Elez, Salma Kaochar, Scott E Kopetz, Xiao-Nan Li, Funda Meric-Bernstam, Clifford A Meyer, Haiwei Mou, Kristen M Naegle, Martin Pera, Zinaida Perova, Katerina A Politi, Benjamin J Raphael, Paul Robson, Rosalie C Sears, Josep Tabernero, David A Tuveson, Alana L Welm, Bryan E Welm, Christopher D Willey, Konstantin Salnikow, Jeffrey H Chuang, and Xiling Shen

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    A pilot metabolomic study of drug interaction with the immune response to seasonal influenza vaccination., Amnah Siddiqa, Yating Wang, Maheshwor Thapa, Dominique E Martin, Andreia N Cadar, Jenna M Bartley, and Shuzhao Li

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    Application of 4-D ultrasound-derived regional strain and proteomics analysis in, Frederick W Damen, Daniel P Gramling, Dorothy Ahlf Wheatcraft, Robert Y Wilpan, Mauro W Costa, and Craig J Goergen

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    A quantitative evaluation of topological motifs and their coupling in gene circuit state distributions., Benjamin Clauss and Mingyang Lu

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    Architecture of the outbred brown fat proteome defines regulators of metabolic physiology., Haopeng Xiao, Luiz H M Bozi, Yizhi Sun, Christopher L Riley, Vivek M. Philip, Mandy Chen, Jiaming Li, Tian Zhang, Evanna L Mills, Margo P Emont, Wenfei Sun, Anita Reddy, Ryan Garrity, Jiani Long, Tobias Becher, Laura Potano Vitas, Dina Laznik-Bogoslavski, Martha Ordonez, Xinyue Liu, Xiong Chen, Yun Wang, Weihai Liu, Nhien Tran, Yitong Liu, Yang Zhang, Aaron M Cypess, Andrew P White, Yuchen He, Rebecca Deng, Heiko Schöder, Joao A Paulo, Mark P Jedrychowski, Alexander S Banks, Yu-Hua Tseng, Paul Cohen, Linus T Tsai, Evan D Rosen, Samuel Klein, Maria Chondronikola, Fiona E McAllister, Nick Van Bruggen, Edward L Huttlin, Bruce M Spiegelman, Gary Churchill, Steven P Gygi, and Edward T Chouchani

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    A reference human induced pluripotent stem cell line for large-scale collaborative studies., Caroline B Pantazis, Andrian Yang, Erika Lara, Justin A McDonough, Cornelis Blauwendraat, Lirong Peng, Hideyuki Oguro, Jitendra Kanaujiya, Jizhong Zou, David Sebesta, Gretchen Pratt, Erin Cross, Jeffrey Blockwick, Philip Buxton, Lauren Kinner-Bibeau, Constance Medura, Christopher Tompkins, Stephen Hughes, Marianita Santiana, Faraz Faghri, Mike A Nalls, Daniel Vitale, Shannon Ballard, Yue A Qi, Daniel M Ramos, Kailyn M Anderson, Julia Stadler, Priyanka Narayan, Jason Papademetriou, Luke Reilly, Matthew P Nelson, Sanya Aggarwal, Leah U Rosen, Peter Kirwan, Venkat Pisupati, Steven L Coon, Sonja W Scholz, Theresa Priebe, Miriam Öttl, Jian Dong, Marieke Meijer, Lara J M Janssen, Vanessa S Lourenco, Rik van der Kant, Dennis Crusius, Dominik Paquet, Ana-Caroline Raulin, Guojun Bu, Aaron Held, Brian J Wainger, Rebecca M C Gabriele, Jackie M Casey, Selina Wray, Dad Abu-Bonsrah, Clare L Parish, Melinda S Beccari, Don W Cleveland, Emmy Li, Indigo V L Rose, Martin Kampmann, Carles Calatayud Aristoy, Patrik Verstreken, Laurin Heinrich, Max Y Chen, Birgitt Schüle, Dan Dou, Erika L F Holzbaur, Maria Clara Zanellati, Richa Basundra, Mohanish Deshmukh, Sarah Cohen, Richa Khanna, Malavika Raman, Zachary S Nevin, Madeline Matia, Jonas Van Lent, Vincent Timmerman, Bruce R Conklin, Katherine Johnson Chase, Ke Zhang, Salome Funes, Daryl A Bosco, Lena Erlebach, Marc Welzer, Deborah Kronenberg-Versteeg, Guochang Lyu, Ernest Arenas, Elena Coccia, Lily Sarrafha, Tim Ahfeldt, John C Marioni, William C Skarnes, Mark R Cookson, Michael E Ward, and Florian T Merkle

     

    Are Genetic Effects on Gene Expression Correlated Within TAD Boundaries?, Alexander Daines

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    Assembly of 43 human Y chromosomes reveals extensive complexity and variation., Pille Hallast, Peter Ebert, Mark Loftus, Feyza Yilmaz, Peter A Audano, Glennis A Logsdon, Marc Jan Bonder, Weichen Zhou, Wolfram Höps, Kwondo Kim, Chong Li, Savannah J Hoyt, Philip C Dishuck, David Porubsky, Fotios Tsetsos, Jee Young Kwon, Qihui Zhu, Katherine M Munson, Patrick Hasenfeld, William T Harvey, Alexandra P Lewis, Jennifer Kordosky, Kendra Hoekzema, Human Genome Structural Variation Consortium (HGSVC), Rachel J O'Neill, Jan O Korbel, Chris Tyler-Smith, Evan E Eichler, Xinghua Shi, Christine R Beck, Tobias Marschall, Miriam K Konkel, and Charles Lee

     

    Assessing GPX4 as a Blood-Based Biomarker via a LLM-engaged Gene Prioritization and Characterization Workflow, Bishesh Subba

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    Assessing the potential relevance of CEACAM6 as a blood transcriptional biomarker, Darawan Rinchai and Damien Chaussabel

     

    Assessing the Potential Relevance of TMOD1 as a Blood Transcriptional Biomarker, Fuadur Omi

     

    Assessment of axonal regeneration in Gjb1/CMT1X mouse model, Alsu Shagieva

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    Assessment of brain cancer atlas maps with multimodal imaging features., Enrico Capobianco and Marco Dominietto

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    Assessment of the Glycan-Binding Profile of Pseudomonas aeruginosa PAO1., Hector Sanchez, George A O'Toole, and Brent Berwin

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    Associations between HLA class II alleles and IgE sensitization to allergens in the Qatar Biobank cohort, Taushif Khan, Isabella Marie Ledoux, Ferdousey Aziz, Fatima Al Ali, Evonne Chin-Smith, Manar Ata, Mohammed Yousuf Karim, and Nico Mar

     

    Associations of the skin, oral and gut microbiome with aging, frailty and infection risk reservoirs in older adults., Peter J Larson, Wei Zhou, Alba Santiago, Sarah Driscoll, Elizabeth Fleming, Anita Y Voigt, Ock K Chun, James J Grady, George A Kuchel, Julie T Robison, and Julia Oh

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    A standardized nomenclature for mammalian histone genes., Ruth L Seal, Paul Denny, Elspeth A Bruford, Anna K Gribkova, David Landsman, William F Marzluff, Monica McAndrews, Anna R Panchenko, Alexey K Shaytan, and Paul B Talbert

     

    A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations., Beatriz Batista Trigo, Natália Fonseca Alves, Marco Milanesi, José Fernando Garcia, Endashaw Terefe, Olivier Hanotte, Abdulfatai Tijjani, and Yuri Tani Utsunomiya

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    At-home blood collection and stabilization in high temperature climates using, Lauren G Brown, Amanda J Haack, Dakota S Kennedy, Karen N Adams, Jennifer E Stolarczuk, Meg G Takezawa, Erwin Berthier, Sanitta Thongpang, Fang Yun Lim, Damien Chaussabel, Mathieu Garand, and Ashleigh B Theberge

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    A training curriculum for retrieving, structuring, and aggregating information derived from the biomedical literature and large-scale data repositories, Darawan Rinchai and Damien Chaussabel

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    A TRANSCRIPTOMIC APPRECIATION OF CHILDHOOD MENINGOCOCCAL AND POLYMICROBIAL SEPSIS FROM A PRO-INFLAMMATORY AND TRAJECTORIAL PERSPECTIVE, A ROLE FOR VASCULAR ENDOTHELIAL GROWTH FACTOR A AND B MODULATION?, Asrar Rashid, Berit S Brusletto, Feras Al-Obeidat, Mohammed Toufiq, Govind Benakatti, Joe Brierley, Zainab A Malik, Zain Hussain, Hoda Alkhazaimi, Javed Sharief, Raziya Kadwa, Amrita Sarpal, Damien Chaussabel, Rayaz A Malik, Nasir Quraishi, Praveen Khilnani, Syed A Zaki, Rashid Nadeem, Guftar Shaikh, Ahmed Al-Dubai, Wael Hafez, and Amir Hussain

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    A Unique Role for Protocadherin γC3 in Promoting Dendrite Arborization through an Axin1-Dependent Mechanism., David M Steffen, Camille M Hanes, Kar Men Mah, Paula Valiño Ramos, Peter J Bosch, Dalton C Hinz, Jason J Radley, Robert W. Burgess, Andrew M Garrett, and Joshua A Weiner

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    A universal method for generating knockout mice in multiple genetic backgrounds using zygote electroporation., Tomohiro Tamari, Yoshihisa Ikeda, Kento Morimoto, Keiko Kobayashi, Saori Mizuno-Iijima, Shinya Ayabe, Akihiro Kuno, Seiya Mizuno, and Atsushi Yoshiki

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    Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment., Michael Chiorazzi, Jan Martinek, Bradley Krasnick, Yunjiang Zheng, Keenan J Robbins, Rihao Qu, Gabriel Kaufmann, Zachary Skidmore, Melani Juric, Laura A Henze, Frederic Brösecke, Adam Adonyi, Jun Zhao, Liang Shan, Esen Sefik, Jacqueline Mudd, Ye Bi, S Peter Goedegebuure, Malachi Griffith, Obi Griffith, Abimbola Oyedeji, Sofia Fertuzinhos, Rolando Garcia-Milian, Daniel Boffa, Frank Detterbeck, Andrew Dhanasopon, Justin Blasberg, Benjamin Judson, Scott Gettinger, Katerina Politi, Yuval Kluger, Karolina Palucka, Ryan C Fields, and Richard A Flavell

     

    Automated Assessment of Feeding Behaviors in Mice Using Machine Vision, Cayson Hamilton

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    Autosomal recessive LRP1-related syndrome featuring cardiopulmonary dysfunction, bone dysmorphology, and corneal clouding., Paul R Mark, Stephen A. Murray, Tao Yang, Alexandra Eby, Angela Lai, Di Lu, Jacob Zieba, Surender Rajasekaran, Elizabeth A VanSickle, Linda Z Rossetti, Lucia Guidugli, Kelly Watkins, Meredith S Wright, Caleb P Bupp, and Jeremy W Prokop

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    Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity., Nagender Ledala, Mishika Malik, Karim Rezaul, Sara Paveglio, Anthony Provatas, Aaron Kiel, Melissa Caimano, Yanjiao Zhou, Jonathan Lindgren, Kristyna Krasulova, Peter Illes, Zdeněk Dvořák, Sandhya Kortagere, Sabine Kienesberger, Amar Cosic, Lisa Pöltl, Ellen L Zechner, Subho Ghosh, Sridhar Mani, Justin D Radolf, and Adam P Matson

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    Baseline immune states (BIS) associated with vaccine responsiveness and factors that shape the BIS., Djamel Nehar-Belaid, Mark Sokolowski, Sathyabaarathi Ravichandran, Jacques Banchereau, Damien Chaussabel, and Duygu Ucar

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    Behavioral phenotypes revealed during reversal learning are linked with novel genetic loci in diversity outbred mice., Jared R Bagley, Lauren S Bailey, Leona H. Gagnon, Hao He, Vivek M. Philip, Laura G Reinholdt, Lisa M Tarantino, Elissa J Chesler, and James D Jentsch

     

    Benchmarking algorithms to infer chromatininteractions from single-cell ATAC-seq data, Matthew Signorotti

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    Bifidobacterial carbohydrate/nucleoside metabolism enhances oxidative phosphorylation in white adipose tissue to protect against diet-induced obesity., Gihyeon Kim, Youngmin Yoon, Jin Ho Park, Jae Won Park, Myung-Guin Noh, Hyun Kim, Changho Park, Hyuktae Kwon, Jeong-Hyeon Park, Yena Kim, Jinyoung Sohn, Shinyoung Park, Hyeonhui Kim, Sun-Kyoung Im, Yeongmin Kim, Ha Yung Chung, Myung Hee Nam, Jee Young Kwon, Il Yong Kim, Yong Jae Kim, Ji Hyeon Baek, Hak Su Kim, George M Weinstock, Belong Cho, Charles Lee, Sungsoon Fang, Hansoo Park, and Je Kyung Seong

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    Biochemical pathways represented by Gene Ontology-Causal Activity Models identify distinct phenotypes resulting from mutations in pathways., David P. Hill, Harold J. Drabkin, Cynthia Smith, Kimberly M Van Auken, and Peter D'Eustachio

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    Biofabrication of 3D breast cancer models for dissecting the cytotoxic response of human T cells expressing engineered MAIT cell receptors., Madhuri Dey, Myong Hwan Kim, Momoka Nagamine, Ece Karhan, Lina Kozhaya, Mikail Dogan, Derya Unutmaz, and Ibrahim T Ozbolat

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    Biotransformation of Organophosphate Esters by Rice and Rhizosphere Microbiome: Multiple Metabolic Pathways, Mechanism, and Toxicity Assessment., Yuanyuan Yu, Xiaolong Yu, Dongqing Zhang, Ling Jin, Jiahui Huang, Xifen Zhu, Jianteng Sun, Miao Yu, and Lizhong Zhu

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    Blackcurrants Reduce the Risk of Postmenopausal Osteoporosis: A Pilot Double-Blind, Randomized, Placebo-Controlled Clinical Trial., Briana M Nosal, Junichi R Sakaki, Zachary Macdonald, Kyle Mahoney, Kijoon Kim, Matthew Madore, Staci Thornton, Thi Dong Binh Tran, George M. Weinstock, Elaine Choung-Hee Lee, and Ock K Chun

    PDF

    BMP10 functions independently from BMP9 for the development of a proper arteriovenous network., Hyunwoo Choi, Bo-Gyeong Kim, Yong Hwan Kim, Se-Jin Lee, Young Jae Lee, and S Paul Oh

    Link

    Bones and Teeth, Peter Vogel, John P Sundberg, and Cheryl Ackert-Bicknell

     

    Brain and spinal cord lesions in 28 inbred strains of aging mice., Jerrold M Ward, Peter Vogel, and John P Sundberg

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    Bridging mouse and human anatomies; a knowledge-based approach to comparative anatomy for disease model phenotyping., Jesús Ruberte, Paul N Schofield, John P Sundberg, Alfonso Rodriguez-Baeza, Ana Carretero, and Colin McKerlie

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    Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease., Stacey J Sukoff Rizzo, Gregg Homanics, David J Schaeffer, Lauren Schaeffer, Jung Eun Park, Julia Oluoch, Tingting Zhang, Annat Haber, Nicholas T Seyfried, Benedict Paten, Anna Greenwood, Takeshi Murai, Sang Ho Choi, Hasi Huhe, Julia Kofler, Peter L Strick, Gregory W. Carter, and Afonso C Silva

     

    Bxb1-Integrase and Modified Bacterial Artificial Chromosomes as a Tool for Site-Specific Transgenesis of Large Donor DNA into Mouse Models, Thomas Mehaffey

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    Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice., Jessica M Snyder, Kerriann M Casey, Andrzej Galecki, David E Harrison, Hashan Jayarathne, Navasuja Kumar, Francesca Macchiarini, Nadia Rosenthal, Marianna Sadagurski, Adam B Salmon, Randy Strong, Richard A Miller, and Warren Ladiges

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    Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis., M Chauvin, M-C Meinsohn, S Dasari, P May, S Iyer, N M P Nguyen, E Oliva, Z Lucchini, N Nagykery, A Kashiwagi, R Mishra, Richard S. Maser, Julie Wells, Carol J Bult, A K Mitra, Patricia K Donahoe, and D Pépin

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    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors., Joshy George, Yaohui Chen, Nourhan Abdelfattah, Keiko Yamamoto, Thomas D Gallup, Scott I Adamson, Brad Rybinski, Anuj Srivastava, Parveen Kumar, Min Gyu Lee, David S Baskin, Wen Jiang, Jong Min Choi, William Flavahan, Jeffrey Chuang, Betty Ys Kim, Jiaqiong Xu, Sung Yun Jung, and Kyuson Yun

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    Canine as a Comparative and Translational Model for Human Mammary Tumor., Jee Young Kwon, Nicholas Moskwa, Wonyoung Kang, Timothy M Fan, and Charles Lee

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    Carbamoylated Erythropoietin-Induced Cerebral Blood Perfusion and Vascular Gene Regulation., Jayanarayanan Sadanandan, Monica Sathyanesan, Yutong Liu, Neeraj K Tiwari, and Samuel S Newton

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    Causes of death and conditional survival estimates of long-term lung cancer survivors., Qun Zhang, Yuan Dai, Hongda Liu, Wenkui Sun, Yuming Huang, Zheng Gong, Shanlin Dai, Hui Kong, and Weiping Xie

     

    Cell Cycle Changes Following TPHP Exposure of Induced Pluripotent Stem Cells, Lacie Low

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    Challenges and Future Prospects of Targeting Myostatin/Activin A Signaling to Treat Diseases of Muscle Loss and Metabolic Dysfunction., Se-Jin Lee, Shalender Bhasin, Lloyd Klickstein, Venkatesh Krishnan, and Daniel Rooks

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    Challenges and opportunities for modeling aging and cancer., Olga Anczuków, Susan Airhart, Jeffrey Chuang, Lisa M Coussens, George A Kuchel, Ron Korstanje, Sheng Li, Anna Lisa Lucido, Sandra S McAllister, Katerina Politi, Kornelia Polyak, Timothy Ratliff, Guangwen Ren, Jennifer J. Trowbridge, Duygu Ucar, and Karolina Palucka

     

    Characterization of Glycosylation in a Cancer Model, Elaine Schumacher

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    Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics., Hongyuan Xu, Johanna Bensalel, Sunil Raju, Enrico Capobianco, Michael L Lu, and Jianning Wei

     

    Characterization of Spontaneous Sugar Modifications of Proteins, Lily Sabol

     

    Characterization of the Pulmonary Phenotype of a Zfhx4 Mutant Mouse Model During Embryonic Development, Sara Hunstad

     

    Characterizing de novo variants in the CRISPR-Cas9 edited KOLF2.2J iPSC cell line, Alyssa Lima

     

    Characterizing neuromuscular degeneration in mouse models of rare neuromuscular disease through neurogenic and myogenic attributes, Aria Ma

     

    Characterizing retinal vascular development in New Zealand Obese mice, Julia Klein

     

    Characterizing the C57BL/6J-Ighmbp2C495del mouse strainas a model for the study of SMARD1, Harold Peón Castro

     

    Characterizing TNF-alpha levels in the context of Dnmt3a-mutant bone marrow, Brandon James

     

    Characterizing Weighted Gene Correlation Network Analysis Module Quantitative Trait Loci Through Local and Distal Expression Quantitative Trait Loci Across Four Tissues in Diversity Outbred Mice, Zoe Vittum

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    CHEK2 signaling is the key regulator of oocyte survival after chemotherapy., Chihiro Emori, Zachary Boucher, and Ewelina Bolcun-Filas

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    Chemotherapeutics and CAR-T Cell-Based Immunotherapeutics Screening on a 3D Bioprinted Vascularized Breast Tumor Model, Madhuri Dey, Myoung Hwan Kim, Mikail Dogan, Momoka Nagamine, Lina Kozhaya, Nazmiye Celik, Derya Unutmaz, and Ibrahim T. Ozbolat

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    ChIATAC is an efficient strategy for multi-omics mapping of 3D epigenomes from low-cell inputs., Haoxi Chai, Harianto Tjong, Peng Li, Wei Liao, Ping Wang, Chee-Hong Wong, Chew Yee Ngan, Warren J Leonard, Chia-Lin Wei, and Yijun Ruan

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    Children's Oncology Group's 2023 blueprint for research: Germ cell tumors., Roma Bhuta, Rachana Shah, Joanna J Gell, Jenny N Poynter, Aditya Bagrodia, Bryan J Dicken, Farzana Pashankar, A Lindsay Frazier, and Furqan Shaikh

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    Chow diet in mouse aging studies: nothing regular about it., Jennifer Lee, Chloe Purello, Sarah L Booth, Brian Bennett, Christopher D Wiley, and Ron Korstanje

     

    Chromatin Looping Differences between 129S and CAST Mice Regulate Transcriptional Variation, Beatriz Alvarez

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    Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models., Yunlu Xue, Xiaomei Sun, Sean K Wang, Gayle B. Collin, Vladimir J Kefalov, and Constance L Cepko

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    Citizen science data reveal regional heterogeneity in phenological response to climate in the large milkweed bug,, Alexis Garretson, Tedra Cuddy, Alexandra G Duffy, iNaturalist Citizen Scientists, and Rebecca E Forkner

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    Clathrin light chain-conjugated drug delivery for cancer., Sungwook Jung, Liwei Jiang, Jing Zhao, Leonard D. Shultz, Dale L Greiner, Munhyung Bae, Xiaofei Li, Farideh Ordikhani, Rui Kuai, John Joseph, Vivek Kasinath, David R Elmaleh, and Reza Abdi

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    Clinically relevant mouse models of Charcot-Marie-Tooth type 2S., Paige B Martin, Sarah E Holbrook, Amy N Hicks, Timothy J Hines, Laurent P. Bogdanik, Robert W. Burgess, and Gregory A. Cox

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    Clinical validity assessment of genes frequently tested on intellectual disability/autism sequencing panels., Erin Rooney Riggs, Taylor I Bingaman, Carrie-Ann Barry, Andrea Behlmann, Krista Bluske, Bret Bostwick, Alison Bright, Chun-An Chen, Amanda R Clause, Avinash V Dharmadhikari, Mythily Ganapathi, Claudia Gonzaga-Jauregui, Andrew R Grant, Madeline Y Hughes, Se Rin Kim, Amanda Krause, Jun Liao, Aimé Lumaka, Michelle Mah, Caitlin M Maloney, Shruthi Mohan, Ikeoluwa A Osei-Owusu, Emma Reble, Olivia Rennie, Juliann M Savatt, Hermela Shimelis, Rebecca K Siegert, Tam P Sneddon, Courtney Thaxton, Kelly A Toner, Kien Trung Tran, Ryan Webb, Emma H Wilcox, Jiani Yin, Xinming Zhuo, Masa Znidarsic, Christa Lese Martin, Catalina Betancur, Jacob A S Vorstman, David T Miller, and Christian P Schaaf

    Link

    Clonal hematopoiesis, aging and Alzheimer's disease., Pablo Sánchez Vela, Jennifer J. Trowbridge, and Ross L Levine

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    Cognitive impairment in post-acute sequelae of COVID-19 and short duration myalgic encephalomyelitis patients is mediated by orthostatic hemodynamic changes., Heather Day, Brayden Yellman, Sarah Hammer, Candace Rond, Jennifer Bell, Saeed Abbaszadeh, Greg Stoddard, Derya Unutmaz, Lucinda Bateman, and Suzanne D Vernon

     

    Combination Organelle Mitochondrial Endoplasmic Reticulum Therapy (COMET) for Multidrug Resistant Breast Cancer., Lara Scheherazade Milane, Saket Dolare, Guangwen Ren, and Mansoor Amiji

     

    Comparative effects of acute inflammatory challenge on hematopoietic stem cell differentiation in mouse models of clonal hematopoiesis., Hanna Kodama

     

    Comparing Gene Sets by Comparing Gene Enrichmen, Irissa Machetta

     

    Comparing Ovarian Reserve Damage Response to Different Sources of Radiation Exposure, Paris Guerrero

     

    Comparison of eQTL Identification when using Single-end or Paired- end RNA-sequencing Data, Sam Ardery

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    Compendium-Wide Analysis of Pseudomonas aeruginosa Core and Accessory Genes Reveals Transcriptional Patterns across Strains PAO1 and PA14., Alexandra J Lee, Georgia Doing, Samuel L Neff, Taylor Reiter, Deborah A Hogan, and Casey S Greene

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    Complexity of the marine ecosystem in view of the human health factors: role of network science, Enrico Capobianco and Pier Francesco Moretti

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    Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice., Manuela A Oestereicher, Janine M Wotton, Shinya Ayabe, Ghina Bou About, Tsz Kwan Cheng, Jae-Hoon Choi, Dave Clary, Emily M Dew, Lahcen Elfertak, Alain Guimond, Hamed Haseli Mashhadi, Jason D Heaney, Lois Kelsey, Piia Keskivali-Bond, Federico Lopez Gomez, Susan Marschall, Michael McFarland, Hamid Meziane, Violeta Munoz Fuentes, Ki-Hoan Nam, Zuzana Nichtová, Dale Pimm, Lynette Bower, Jan Prochazka, Jan Rozman, Luis Santos, Michelle Stewart, Nobuhiko Tanaka, Christopher S Ward, Amelia M Willett, Robert Wilson, Robert E Braun, Mary E Dickinson, Ann M Flenniken, Yann Herault, K C Kent Lloyd, Ann-Marie Mallon, Colin McKerlie, Stephen A. Murray, Lauryl M J Nutter, Radislav Sedlacek, Je Kyung Seong, Tania Sorg, Masaru Tamura, Sara Wells, Elida Schneltzer, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabe de Angelis, Jacqueline K White, and Nadine Spielmann

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    Concomitant inhibition of PPARγ and mTORC1 induces the differentiation of human monocytes into highly immunogenic dendritic cells., Fernando Erra Diaz, Ignacio Mazzitelli, Lucía Bleichmar, Claudia Melucci, Asa Thibodeau, Tomás Dalotto Moreno, Radu Marches, Gabriel A Rabinovich, Duygu Ucar, and Jorge Geffner

     

    Considerations for policymakers for improving health care through telegenetics: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)., Heather E Williams, Lila Aiyar, Mary Beth Dinulos, David Flannery, Michelle L McClure, Michele A Lloyd-Puryear, Kunal Sanghavi, Tracy L Trotter, David Viskochil, and ACMG Advocacy and Government Affairs Committee

     

    Contrasting Osteosarcoma and Epithelial Breast Cancer Immune Regulation in Murine Cell Lines, Juliana Fenimore

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    Co-option of endogenous retroviruses through genetic escape from TRIM28 repression., Rocio Enriquez-Gasca, Poppy A Gould, Hale Tunbak, Lucia Conde, Javier Herrero, Alexandra Chittka, Christine R Beck, Robert Gifford, and Helen M Rowe

     

    Cortex-wide In-vivo Two-photon Calcium Imaging Analysis of Mice During Skilled Reaching, Andrea Ruiz D'Argence

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    Cry1 expression during postnatal development is critical for the establishment of normal circadian period, Aaron E Schirmer, Vivek Kumar, Andrew Schook, Eun Joo Song, Michael S Marshall, and Joseph S Takahashi

     

    Current Views on Chr10q26 Contribution to Age-Related Macular Degeneration., Navdeep Gogna, Lillian F Hyde, Gayle B. Collin, Lisa Stone, Jurgen K Naggert, and Patsy M. Nishina

     

    Cyfip2 allelic variation in C57BL/6J and C57BL/6NJ mice alters free-choice ethanol drinking but not binge-like drinking or wheel-running activity., Matthew C Hartmann, Walter D McCulley, Sarah E Holbrook, Megan M Haney, Caitlin G Smith, Vivek Kumar, and Alan M Rosenwasser

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    Cytokine release syndrome and cancer immunotherapies - historical challenges and promising futures., Deep Shah, Brian Soper, and Lindsay S. Shopland

     

    Data Annotation Module for Frictionless Data, Naomie Gao

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    Deciphering the role of RNA structure in translation efficiency., Jianan Lin, Yang Chen, Yuping Zhang, Haifan Lin, and Zhengqing Ouyang

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    Deep learning image analysis quantifies tumor heterogeneity and identifies microsatellite instability in colon cancer., Jill C Rubinstein, Ali Foroughi Pour, Jie Zhou, Todd B Sheridan, Brian S White, and Jeffrey Chuang

     

    Determining the Role of KZFPs in Modulating Chromatin Accessibilityand Gene Expression in Mouse Embryonic Stem Cells, Alex J. Mora Pagán

     

    Determining the Role of the ELF3 gene in trophoblast cell differentiation. The Jacksons Laboratory Summer Student Program, Abraham Lopez

     

    Developing and Using an R Package To Identify Causative Variations Driving Gene eQTL, Bryant Luna-Ramos

     

    Development of a human iPSC tool kit containing the CRISPR/CAS based Castilio system to test complex genetic circuits in cell differentiation, Annika Bai

     

    Development of a solubility parameter calculation-based method as a complementary tool to traditional techniques for indoor dust microplastic determination and risk assessment., Shanjun Song, Limei Cai, Yuhui Liu, Zijuan Peng, Chunyu Liu, Hui Jiao, Penghui Li, Qian Liu, Miao Yu, Tao Zhou, Qinghe Zhang, Henner Hollert, Xingchen Zhao, and Guibin Jiang

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    Differential regulation of gene expression pathways with dexamethasone and ACTH after early life seizures., Jeffrey L Brabec, Mohamed Ouardouz, J Matthew Mahoney, Rod C Scott, and Amanda E Hernan

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    Differential splicing of neuronal genes in a Trem2*R47H mouse model mimics alterations associated with Alzheimer's disease., Ravi S Pandey, Kevin P Kotredes, Michael Sasner, Gareth R Howell, and Gregory W. Carter

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    Diffuse alveolar hemorrhage in children with interstitial lung disease: Determine etiologies!, Katrin Knoflach, Christina Katharina Rapp, Nicolaus Schwerk, Julia Carlens, Martin Wetzke, Nagehan Emiralioğlu, Nural Kiper, Astrid Madsen Ring, Frederik Buchvald, Effrosyni Manali, Spyros Papiris, Simone Reu-Hofer, Matthias Kappler, Alexandra Schieber, Elias Seidl, Florian Gothe, Peter N Robinson, and Matthias Griese

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    Direct cell-to-cell transfer in stressed tumor microenvironment aggravates tumorigenic or metastatic potential in pancreatic cancer., Giyong Jang, Jaeik Oh, Eunsung Jun, Jieun Lee, Jee Young Kwon, Jaesang Kim, Sang-Hyuk Lee, Song Cheol Kim, Sung-Yup Cho, and Charles Lee

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    Discovering and Validating Mouse Models of Human Diseases: The Cinderella Effect, John P Sundberg, Jerrold M. Ward, Peter Vogel, and Paul N. Schofield

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    Distinct roles of estrone and estradiol in endothelial colony-forming cells., Alicia Ivory and Andrew S Greene

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    Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis., Jennifer M. SanMiguel, Elizabeth Eudy, Matthew A. Loberg, Kira Young, Jayna J. Mistry, Kristina D. Mujica, Logan S. Schwartz, Timothy M. Stearns, Grant A Challen, and Jennifer J. Trowbridge

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    Diversification of the ruminant skull along an evolutionary line of least resistance., Daniel P Rhoda, Annat Haber, and Kenneth D Angielczyk

     

    DNA methylation provides diagnostic value for meningioma recurrence in clinical practice., Erica Shen, Nathan K Leclair, Kristi Herlth, Melissa Soucy, Nicholas Renzette, Xinming Zhuo, Kevin Kelly, Greg Omerza, Hilary Onyiuke, Ian McNeill, Leo Wolansky, Kevin Becker, Lei Li, Qian Wu, and Ketan R Bulsara

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    Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma., Alan T Yeo, Rushil Shah, Konstantinos Aliazis, Rinku Pal, Tuoye Xu, Piyan Zhang, Shruti Rawal, Christopher M Rose, Frederick S Varn, Vicky A Appleman, Joon Yoon, Hemant Varma, Steven P Gygi, Roel G W Verhaak, Vassiliki A Boussiotis, and Al Charest

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    Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex without dystonia musculorum., Thomas J. Sproule, Robert Y Wilpan, John J Wilson, Benjamin E. Low, Yudai Kabata, Tatsuo Ushiki, Riichiro Abe, Michael V. Wiles, Derry C. Roopenian, and John P Sundberg

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    Early experience with targeted therapy as a first-line adjuvant treatment for pediatric low-grade glioma., Nathan K Leclair, William Lambert, Kimberley Roche, Eileen Gillan, Joanna J Gell, Ching C Lau, Gregory Wrubel, Joshua Knopf, Shirali Amin, Megan Anderson, Jonathan E Martin, Markus J Bookland, and David S Hersh

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    Early radial positional information in the cochlea is optimized by a precise linear BMP gradient and enhanced by SOX2., Matthew J Thompson, Caryl A Young, Vidhya Munnamalai, and David M Umulis

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    Editorial: Genetic basis of tolerance induction defects underlying the development of autoimmune pathologies., Jeremy Racine, Laurence Morel, Yi-Guang Chen, and David V. Serreze

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    Editorial: Physiology in extreme conditions: Adaptations and unexpected reactions, Volume II., Maria G Trivella, Enrico Capobianco, and Antonio L'Abbate

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    Editorial: Stromal and immune microenvironment in breast cancer metastasis., Xin Lu, Xia Liu, Toni Celià-Terrassa, and Guangwen Ren

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    Editorial: Targeting glucose metabolism in cancer immunity and immunotherapy., Olivier Feron, Chih-Hao Chang, and Frédérique Végran

     

    Effect of hair cell orientation on mechanotransduction response in the vestibular system, Kayla Bright

     

    Effects of Microglia Depletion on Dendritic Spine Architecture in Genetically Distinct Alzheimer's Disease Mouse Models, Harry Chen

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    Effects of Probiotics on Colitis-Induced Exacerbation of Alzheimer's Disease in, Bijayani Sahu, Lauren M Johnson, Mona Sohrabi, Anastasia A Usatii, Rachel M J Craig, Joshua B Kaelberer, Sathiya Priya Chandrasekaran, Harpreet Kaur, Suba Nookala, and Colin K Combs

     

    Efficacy of a High Fat Diet and L-NAME Combinatory Mouse Model for Heart Failure With Preserved Ejection Fraction, Maggie Peng

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    Efficient in vivo neuronal genome editing in the mouse brain using nanocapsules containing CRISPR-Cas9 ribonucleoproteins., Jeanette M Metzger, Yuyuan Wang, Samuel S Neuman, Kathy J. Snow, Stephen A. Murray, Cathleen Lutz, Viktoriya Bondarenko, Jesi Felton, Kirstan Gimse, Ruosen Xie, Dongdong Li, Yi Zhao, Matthew T Flowers, Heather A Simmons, Subhojit Roy, Krishanu Saha, Jon E Levine, Marina E Emborg, and Shaoqin Gong

     

    Elucidating Gli3 and Hand2 interactions in the developing mandible, Aria Hossain

     

    Employing ChIP-Seq to Identify Novel Genes and Pathways for Congenital Diaphragmatic Hernia (CDH), Syed Ali

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    Engineering a "detect and destroy" skin probiotic to combat methicillin-resistant Staphylococcus aureus., Changhui Guan, Peter J Larson, Elizabeth Fleming, Alexander P Tikhonov, Sara Mootien, Trudy H Grossman, Caroline Golino, and Julia Oh

     

    Engineering Human MAIT Cells with Chimeric Antigen Receptors for Cancer Immunotherapy., Mikail Dogan, Ece Karhan, Lina Kozhaya, Lindsey Placek, Xin Chen, Mesut Yigit, and Derya Unutmaz

     

    Engineering induced pluripotent stem cells to capture critical mechanisms of dendritic cells activation, Richard Fu

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    Enhanced performance of gene expression predictive models with protein-mediated spatial chromatin interactions., Mateusz Chiliński, Jakub Lipiński, Abhishek Agarwal, Yijun Ruan, and Dariusz Plewczynski

     

    Enhancing Deep Learning Model Evaluation via Attention Consistency Analysis in Spatial Transcriptomics Data, Dylan Agyemang

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    Epidermal Growth Factor Receptor Inhibition Is Protective in Hyperoxia-Induced Lung Injury., Zachary M Harris, Ying Sun, John Joerns, Brian Clark, Buqu Hu, Asawari Korde, Lokesh Sharma, Hyeon Jun Shin, Edward P Manning, Lindsey Placek, Derya Unutmaz, Gail Stanley, Hyung Chun, Maor Sauler, Govindarajan Rajagopalan, Xuchen Zhang, Min-Jong Kang, and Jonathan L Koff

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    Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia., Xujie Zhao, Ping Wang, Jonathan D Diedrich, Brandon Smart, Noemi Reyes, Satoshi Yoshimura, Jingliao Zhang, Wentao Yang, Kelly Barnett, Beisi Xu, Zhenhua Li, Xin Huang, Jiyang Yu, Kristine Crews, Allen Eng Juh Yeoh, Marina Konopleva, Chia-Lin Wei, Ching-Hon Pui, Daniel Savic, and Jun J Yang

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    Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma., Yige Wu, Nadezhda V Terekhanova, Wagma Caravan, Nataly Naser Al Deen, Preet Lal, Siqi Chen, Chia-Kuei Mo, Song Cao, Yize Li, Alla Karpova, Ruiyang Liu, Yanyan Zhao, Andrew Shinkle, Ilya Strunilin, Cody Weimholt, Kazuhito Sato, Lijun Yao, Mamatha Serasanambati, Xiaolu Yang, Matthew Wyczalkowski, Houxiang Zhu, Daniel Cui Zhou, Reyka G Jayasinghe, Daniel Mendez, Michael C Wendl, David Clark, Chelsea Newton, Yijun Ruan, Melissa A Reimers, Russell K Pachynski, Chris Kinsinger, Scott Jewell, Daniel W Chan, Hui Zhang, Aadel A Chaudhuri, Milan G Chheda, Benjamin D Humphreys, Mehdi Mesri, Henry Rodriguez, James J Hsieh, Li Ding, and Feng Chen

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    Epigenetic memory of coronavirus infection in innate immune cells and their progenitors., Jin-Gyu Cheong, Arjun Ravishankar, Siddhartha Sharma, Christopher N Parkhurst, Simon A Grassmann, Claire K Wingert, Paoline Laurent, Sai Ma, Lucinda Paddock, Isabella C Miranda, Emin Onur Karakaslar, Djamel Nehar-Belaid, Asa Thibodeau, Michael J Bale, Vinay K Kartha, Jim K Yee, Minh Y Mays, Chenyang Jiang, Andrew W Daman, Alexia Martinez de Paz, Dughan Ahimovic, Victor Ramos, Alexander Lercher, Erik Nielsen, Sergio Alvarez-Mulett, Ling Zheng, Andrew Earl, Alisha Yallowitz, Lexi Robbins, Elyse LaFond, Karissa L Weidman, Sabrina Racine-Brzostek, He S Yang, David R Price, Louise Leyre, André F Rendeiro, Hiranmayi Ravichandran, Junbum Kim, Alain C Borczuk, Charles M Rice, R Brad Jones, Edward J Schenck, Robert J Kaner, Amy Chadburn, Zhen Zhao, Virginia Pascual, Olivier Elemento, Robert E Schwartz, Jason D Buenrostro, Rachel E Niec, Franck J Barrat, Lindsay Lief, Joseph C Sun, Duygu Ucar, and Steven Z Josefowicz

    Link

    Epithelial mechanics are maintained by inhibiting cell fusion with age in Drosophila., Ari S Dehn, Levi Duhaime, Navdeep Gogna, Patsy M. Nishina, Kristina Kelley, and Vicki P Losick

     

    Escherichia coli ST131 Associated with Increased Mortality in Bloodstream Infections from Urinary Tract Source., Amanda Brumwell, Granger Sutton, Paul M Lantos, Kate Hoffman, Felicia Ruffin, Lauren Brinkac, Thomas H Clarke, Mark D Adams, Vance G Fowler, Derrick E Fouts, and Joshua T Thaden

     

    Essential function of Slmap in embryonic development and skeletal differentiation, Tess Kelly

     

    Establishing in vitro mES-RPE cells bearing S28C TIMP3 mutation toidentify mouse models for Age Related Macular Degeneration., English Laserna

     

    Evaluating the Role of RFX3 in Kidney Function and Cilial Development in an Alport Syndrome Mouse Model, Isabel Huesa

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    Evaluation of Associations of Growth Differentiation Factor-11, Growth Differentiation Factor-8, and Their Binding Proteins Follistatin and Follistatin-Like Protein-3 With Dementia and Cognition., Anne B Newman, Sheena Patel, Jorge R Kizer, Se-Jin Lee, Shalinder Bhasin, Peggy Cawthon, Nathan LeBrasseur, Russel P Tracy, Peter Ganz, and Steven R Cummings

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    Evaluation of Associations of Growth Differentiation Factor-11, Growth Differentiation Factor-8, and Their Binding Proteins, Follistatin and Follistatin-Like Protein-3, With Measures of Skeletal Muscle Mass, Muscle Strength, and Physical Function in Older Adults., Peggy M Cawthon, Sheena Patel, Anne B Newman, Shalender Bhasin, Liming Peng, Russell P Tracy, Jorge R Kizer, Se-Jin Lee, Luigi Ferrucci, Peter Ganz, Nathan K LeBrasseur, and Steven R Cummings

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    Evaluation of phenotype-driven gene prioritization methods for Mendelian diseases., Julius O B Jacobsen, Catherine Kelly, Valentina Cipriani, Peter N Robinson, and Damian Smedley

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    Evaluation of tarsal injuries in C57BL/6J male mice., Brenda Kick, Laura C. Anderson, Rosalinda A. Doty, Christine Wooley, Meaghan E Dyer, Torrian L Green, Veronica Knickerbocker, Zoe Brown, Samantha Loeber, Janine M Wotton, Bonnie L. Lyons, Linda L Waterman, and Zoë Bichler

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    Exon-intron boundary inhibits m, Zhiyuan Luo, Qilian Ma, Shan Sun, Ningning Li, Hongfeng Wang, Zheng Ying, and Shengdong Ke

     

    Exploration of the Patient-Derived Xenografts at the Jackson Laboratory, Kara Barnao

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    Exploratory studies of oral and fecal microbiome in healthy human aging., Xin Zhou, Baohong Wang, Patrick C Demkowicz, Jethro Johnson, Yanfei Chen, Daniel Spakowicz, Yanjiao Zhou, Yair Dorsett, Lei Chen, Erica Sodergren, George A Kuchel, and George M. Weinstock

     

    Exploring Adipose Cellular Heterogeneity in Mice, Gabriella von Dohlen

     

    Exploring NKT cell and Perforin-mediated regulation of digit tip regeneration in both male and female adult mice, Nina Greeley

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    Extrachromosomal DNA amplifications in cancer., Eunhee Yi, Rocío Chamorro González, Anton G Henssen, and Roel G W Verhaak

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    Extrachromosomal DNA (ecDNA): an origin of tumor heterogeneity, genomic remodeling, and drug resistance., Lauren T Pecorino, Roel G W Verhaak, Anton Henssen, and Paul S Mischel

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    Extrachromosomal DNA in the cancerous transformation of Barrett's oesophagus., Jens Luebeck, Alvin Wei Tian Ng, Patricia C Galipeau, Xiaohong Li, Carissa A Sanchez, Annalise C Katz-Summercorn, Hoon Kim, Sriganesh Jammula, Yudou He, Scott M Lippman, Roel G W Verhaak, Carlo C Maley, Ludmil B Alexandrov, Brian J Reid, Rebecca C Fitzgerald, Thomas G Paulson, Howard Y Chang, Sihan Wu, Vineet Bafna, and Paul S Mischel

     

    Family Screening in DCM: Can Genetics and Baseline Clinical Data Assist Prognostication and Surveillance Planning?, J Travis Hinson and Lisa M. Wren

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    Feasibility and value of genomic profiling in cancer of unknown primary: real-world evidence from prospective profiling study., Ryan W Huey, Aakash Tushar Shah, Honey V Reddi, Priyadarsini Dasari, James T Topham, Hyunsoo Hwang, Nishat Dhillon, Anneleis Willett, Brandon G Smaglo, Jeannelyn S Estrella, Asif Rashid, Aurelio Matamoros, Michael J Overman, Linda Choquette, Greg Omerza, Kevin Kelly, Xuemei Wang, Jonathan M Loree, Jens Rueter, Gauri R Varadhachary, and Kanwal Raghav

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    Focused ultrasound-mediated brain genome editing., Yeh-Hsing Lao, Robin Ji, Joyce K Zhou, Kathy J. Snow, Nancy Kwon, Ethan Saville, Siyu He, Shradha Chauhan, Chun-Wei Chi, Malika S Datta, Hairong Zhang, Chai Hoon Quek, S Sarah Cai, Mingqiang Li, Yaned Gaitan, Lawrence Bechtel, Shih-Ying Wu, Cathleen Lutz, Raju Tomer, Stephen A. Murray, Alejandro Chavez, Elisa E Konofagou, and Kam W Leong

    Link

    Frailty-associated dysbiosis of human microbiotas in older adults in nursing homes., Julia Oh, Julie Robison, and George A Kuchel

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    Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice., Thomas J. Sproule, Robert Y Wilpan, Benjamin E. Low, Kathleen A Silva, Deepak Reyon, J Keith Joung, Michael V. Wiles, Derry C. Roopenian, and John P Sundberg

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    Functional genomics of complex cancer genomes., Francesca Menghi and Edison Liu

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    "FunDNAmethyl" Mechanism for Developmental Restriction of a β-Cell Subpopulation., Cristina Aguayo-Mazzucato and Michael L. Stitzel

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    GA4GH Phenopackets: A Practical Introduction., Markus S Ladewig, Julius O B Jacobsen, Alex H Wagner, Daniel Danis, Baha El Kassaby, Michael Gargano, Tudor Groza, Michael Baudis, Robin Steinhaus, Dominik Seelow, Nikolaos E Bechrakis, Christopher J Mungall, Paul N Schofield, Olivier Elemento, Lindsay Smith, Julie A McMurry, Monica Munoz-Torres, Melissa A Haendel, and Peter N Robinson

     

    GARP on hepatic stellate cells is essential for the development of liver fibrosis, Xiaolong Zhang, Pankaj Sharma, Patrick Maschmeyer, Yu Hu, Mumeng Lou, Jessica Kim, Hodaka Fujii, Derya Unutmaz, Robert F. Schwabe, and Florian Winau

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    GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data., Shoaib Ajaib, Disha Lodha, Steven Pollock, Gemma Hemmings, Martina A Finetti, Arief Gusnanto, Aruna Chakrabarty, Azzam Ismail, Erica Wilson, Frederick S Varn, Bethany Hunter, Andrew Filby, Asa A Brockman, David McDonald, Roel G W Verhaak, Rebecca A Ihrie, and Lucy F Stead

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    Gene expression genetics of the striatum of Diversity Outbred mice., Vivek M. Philip, Haoxi Chai, Michael C Saul, Price E Dickson, Jason A. Bubier, and Elissa J Chesler

     

    Gene fusion dependence in acute myeloid leukemia Ewing sarcoma, and ependymoma cell lines, Aisha Pasha

     

    Generalisable long COVID subtypes: findings from the NIH N3C and RECOVER programmes., Justin T Reese, Hannah Blau, Elena Casiraghi, Timothy Bergquist, Johanna J Loomba, Tiffany J Callahan, Bryan Laraway, Corneliu Antonescu, Ben D Coleman, Michael Gargano, Kenneth J Wilkins, Luca Cappelletti, Tommaso Fontana, Nariman Ammar, Blessy Antony, T M Murali, J Harry Caufield, Guy Karlebach, Julie A McMurry, Andrew Williams, Richard Moffitt, Jineta Banerjee, Anthony E Solomonides, Hannah Davis, Kristin Kostka, Giorgio Valentini, David Sahner, Christopher G Chute, Charisse Madlock-Brown, Melissa A Haendel, and Peter N. Robinson

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    Generalisable long COVID subtypes: findings from the NIH N3C and RECOVER programmes., Justin T Reese, Hannah Blau, Elena Casiraghi, Timothy Bergquist, Johanna J Loomba, Tiffany J Callahan, Bryan Laraway, Corneliu Antonescu, Ben D Coleman, Michael Gargano, Kenneth J Wilkins, Luca Cappelletti, Tommaso Fontana, Nariman Ammar, Blessy Antony, T M Murali, J Harry Caufield, Guy Karlebach, Julie A McMurry, Andrew Williams, Richard Moffitt, Jineta Banerjee, Anthony E Solomonides, Hannah Davis, Kristin Kostka, Giorgio Valentini, David Sahner, Christopher G Chute, Charisse Madlock-Brown, Melissa A Haendel, and Peter N Robinson

     

    Generalized Tree Structure to Annotate Untargeted Metabolomics and Stable Isotope Tracing Data., Shuzhao Li and Shujian Zheng

     

    Generation of the NeoThy mouse model for human immune system studies., Natalia M Del Rio, Liupei Huang, Lydia Murphy, Jayalaxmi Suresh Babu, Cross Matthew Daffada, William John Haynes, James G Keck, Michael A Brehm, Leonard D. Shultz, and Matthew E Brown

     

    Generation of transgenic pluripotent stem cells to overexpress neuronal survival genes against stroke using CRISPR-activation technology, Pilar Saavedra-Weis

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    Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19., Shelly J Robertson, Olivia Bedard, Kristin L McNally, Carl Shaia, Chad S Clancy, Matthew Lewis, Rebecca M Broeckel, Abhilash I Chiramel, Jeffrey G Shannon, Gail L Sturdevant, Rebecca Rosenke, Sarah L Anzick, Elvira Forte, Christoph Preuss, Candice N Baker, Jeffrey M. Harder, Catherine Brunton, Steven C. Munger, Daniel P Bruno, Justin B Lack, Jacqueline M Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E Sturdevant, Jian Sun, Craig Martens, Steven M Holland, Nadia Rosenthal, and Sonja M Best

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    Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy., Karthickeyan Chella Krishnan, Elie-Julien El Hachem, Mark P Keller, Sanjeet G Patel, Luke Carroll, Alexis Diaz Vegas, Isabela Gerdes Gyuricza, Christine Light, Yang Cao, Calvin Pan, Karolina Elżbieta Kaczor-Urbanowicz, Varun Shravah, Diana Anum, Matteo Pellegrini, Chi Fung Lee, Marcus M Seldin, Nadia Rosenthal, Gary Churchill, Alan D Attie, Benjamin Parker, David E James, and Aldons J Lusis

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    Genetic dissection of the pluripotent proteome through multi-omics data integration., Selcan Aydin, Duy T Pham, Tian Zhang, Gregory R Keele, Daniel A Skelly, Joao A Paulo, Matthew Pankratz, Ted Choi, Steven P Gygi, Laura G Reinholdt, Christopher L. Baker, Gary Churchill, and Steven C. Munger

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    Genetic Diversity and Population Structure of Local Sudanese Sheep Populations Revealed by Whole-Genome Sequencing, A Amane, G Belay, Abdulfatai Tijjani, T Dessie, H H. Musa, and O Hanotte

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    Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut., Qijun Zhang, Vanessa Linke, Katherine A Overmyer, Lindsay L Traeger, Kazuyuki Kasahara, Ian J Miller, Daniel E Manson, Thomas J Polaske, Robert L Kerby, Julia H Kemis, Edna A Trujillo, Thiru R Reddy, Jason D Russell, Kathryn L Schueler, Donald S Stapleton, Mary E Rabaglia, Marcus Seldin, Daniel M Gatti, Gregory R Keele, Duy T Pham, Joseph P Gerdt, Eugenio I Vivas, Aldons J Lusis, Mark P Keller, Gary Churchill, Helen E Blackwell, Karl W Broman, Alan D Attie, Joshua J Coon, and Federico E Rey

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    Genetic Mapping of Multiple Traits Identifies Novel Genes for Adiposity, Lipids, and Insulin Secretory Capacity in Outbred Rats., Thu Hong-Le, Wesley L Crouse, Gregory R Keele, Katie Holl, Osborne Seshie, Michael Tschannen, Ann Craddock, Swapan K Das, Alexandria M Szalanczy, Bailey McDonald, Michael Grzybowski, Jason Klotz, Neeraj K Sharma, Aron M Geurts, Chia-Chi Chuang Key, Gregory Hawkins, William Valdar, Richard Mott, and Leah C Solberg Woods

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    Genetic quality: a complex issue for experimental study reproducibility., Atsushi Yoshiki, Gregory Ballard, and Ana V Perez

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    Genetics and Genomics of Addiction., Jason A. Bubier

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    Genome-wide screening reveals the genetic basis of mammalian embryonic eye development., Justine M Chee, Louise Lanoue, Dave Clary, Kendall Higgins, Lynette Bower, Ann Flenniken, Ruolin Guo, David J Adams, Fatima Bosch, Robert E Braun, Steve D M Brown, H-J Genie Chin, Mary E Dickinson, Chih-Wei Hsu, Michael Dobbie, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D Heaney, Yann Herault, Martin Hrabe de Angelis, Fabio Mammano, Lauryl M J Nutter, Helen Parkinson, Chuan Qin, Toshi Shiroishi, Radislav Sedlacek, J-K Seong, Ying Xu, Brian Brooks, Colin McKerlie, K C Kent Lloyd, Henrik Westerberg, and Ala Moshiri

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    Genomic Medicine Year in Review: 2022., Teri A Manolio, Jahnavi Narula, Carol J Bult, Rex L Chisholm, Patricia A Deverka, Geoffrey S Ginsburg, Madison Goldrich, Eric D Green, Gail P Jarvik, George A Mensah, Erin M Ramos, Mary V Relling, Dan M Roden, Robb Rowley, and Marc S Williams

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    Germline thymidylate synthase deficiency impacts nucleotide metabolism and causes dyskeratosis congenita., Hemanth Tummala, Amanda Walne, Roberto Buccafusca, Jenna Alnajar, Anita Szabo, Peter N Robinson, Allyn McConkie-Rosell, Meredith Wilson, Suzanne Crowley, Veronica Kinsler, Anna-Maria Ewins, Pradeepa M Madapura, Manthan Patel, Nikolas Pontikos, Veryan Codd, Tom Vulliamy, and Inderjeet Dokal

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    Global and tissue-specific aging effects on murine proteomes., Gregory R Keele, Ji-Gang Zhang, John Szpyt, Ron Korstanje, Steven P Gygi, Gary Churchill, and Devin K Schweppe

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    Glucose oxidation-dependent survival of activated B cells provides a putative novel therapeutic target for lupus treatment., John J Wilson, Jian Wei, Andrea R Daamen, John D Sears, Elaine Bechtel, Colleen L Mayberry, Grace Stafford, Lesley S Bechtold, Amrie C Grammer, Peter E Lipsky, Derry C. Roopenian, and Chih-Hao Chang

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    GRAPE for fast and scalable graph processing and random-walk-based embedding, Luca Cappelletti, Tommaso Fontana, Elena Casiraghi, Vida Ravanmehr, Tiffany J. Callahan, Carlos Cano, Marcin P. Joachimiak, Christopher J. Mungall, Peter N Robinson, Justin Reese, and Giorgio Valentini

     

    Growth kinetics and treatment of pharyngeal carcinoma in immunodeficient mice, Leah Spade

     

    Guilt by association: EcDNA as a mobile transactivator in cancer., Yanfen Zhu, Liang Gong, and Chia-Lin Wei

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    GZMK(high) CD8(+) T effector memory cells are associated with CD15(high) neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome, Silvia Tiberti, Carlotta Catozzi, Ottavio Croci, Mattia Ballerini, Danilo Cagnina, Chiara Soriani, Caterina Scirgolea, Zheng Gong, Jiatai He, Angeli D Macandog, Amir Nabinejad, Carina B Nava Lauson, Arianna Quinte', Giovanni Bertalot, Wanda L Petz, Simona P Ravenda, Valerio Licursi, Paola Paci, Marco Rasponi, Luca Rotta, Nicola Fazio, Guangwen Ren, Uberto Fumagalli-Romario, Martin H Schaefer, Stefano Campaner, Enrico Lugli, Luigi Nezi, and Teresa Manzo

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    Harnessing large language models (LLMs) for candidate gene prioritization and selection., Mohammed Toufiq, Darawan Rinchai, Eleonore Bettacchioli, Basirudeen Syed Ahamed Kabeer, Taushif Khan, Bishesh Subba, Olivia White, Marina Yurieva, Joshy George, Noemie Jourde-Chiche, Laurent Chiche, Karolina Palucka, and Damien Chaussabel

    Link

    Hematopoietic and Lymphoid Tissues, Harm HogenEsch and John P Sundberg

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    Hematopoietic stem cell aging and leukemia transformation., Patricia A Colom Díaz, Jayna J Mistry, and Jennifer J. Trowbridge

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    HEMDAG: a family of modular and scalable hierarchical ensemble methods to improve Gene Ontology term prediction., Marco Notaro, Marco Frasca, Alessandro Petrini, Jessica Gliozzo, Elena Casiraghi, Peter N Robinson, and Giorgio Valentini

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    Heterogeneity of Islet-Infiltrating IL-21+ CD4 T Cells in a Mouse Model of Type 1 Diabetes., Ashley E Ciecko, Yu Wang, Stephanie Harleston, Amber Drewek, David V. Serreze, Aron M Geurts, Chien-Wei Lin, and Yi-Guang Chen

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    High level of complexity and global diversity of the 3q29 locus revealed by optical mapping and long-read sequencing., Feyza Yilmaz, Umamaheswaran Gurusamy, Trenell J Mosley, Pille Hallast, Kwondo Kim, Yulia Mostovoy, Ryan H Purcell, Tamim H Shaikh, Michael E Zwick, Pui-Yan Kwok, Charles Lee, and Jennifer G Mulle

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    High-resolution microbiome analysis reveals exclusionary Klebsiella species competition in preterm infants at risk for necrotizing enterocolitis., Spencer Coleman, Katrin Unterhauser, Karim Rezaul, Nagender Ledala, Stephanie Lesmes, Melissa J Caimano, Yanjiao Zhou, Eric Jackson, Dawn Gratalo, Mark D Driscoll, and Adam P Matson

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    High sucrose consumption decouples intrinsic and synaptic excitability of AgRP neurons without altering body weight., Austin C Korgan, Klausen Oliveira-Abreu, Wei Wei, Sophie L A Martin, Zoey J D Bridges, José Henrique Leal-Cardoso, Catherine Kaczorowski, and Kristen M S O'Connell

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    High-temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines., Darawan Rinchai, Sara Deola, Gabriele Zoppoli, Basirudeen Syed Ahamed Kabeer, Sara Taleb, Igor Pavlovski, Selma Maacha, Giusy Gentilcore, Mohammed Toufiq, Lisa Mathew, Li Liu, Fazulur Rehaman Vempalli, Ghada Mubarak, Stephan Lorenz, Irene Sivieri, Gabriella Cirmena, Chiara Dentone, Paola Cuccarolo, Daniele Roberto Giacobbe, Federico Baldi, Alberto Garbarino, Benedetta Cigolini, Paolo Cremonesi, Michele Bedognetti, Alberto Ballestrero, Matteo Bassetti, Boris P Hejblum, Tracy Augustine, Nicholas Van Panhuys, Rodolphe Thiebaut, Ricardo Branco, Tracey Chew, Maryam Shojaei, Kirsty Short, Carl G Feng, PREDICT-19 Consortium, Susu M Zughaier, Andrea De Maria, Benjamin Tang, Ali Ait Hssain, Davide Bedognetti, Jean-Charles Grivel, and Damien Chaussabel

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    High-throughput bioprinting of the nasal epithelium using patient-derived nasal epithelial cells., I Deniz Derman, Miji Yeo, Diana Cadena, Megan Callender, Mian Horvath, Zengshuo Mo, Ruoyun Xiong, Elizabeth Fleming, Phylip Chen, Mark E Peeples, Karolina Palucka, Julia Oh, and Ibrahim T Ozbolat

     

    High-Throughput Production of Diverse Xenobiotic Metabolites with Cytochrome P450-Transduced Huh7 Hepatoma Cell Lines., Choon-Myung Lee, Ken H Liu, Grant Singer, Gary W Miller, Shuzhao Li, Dean P Jones, and Edward T Morgan

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    HIV associated cell death: Peptide-induced apoptosis restricts viral transmission., Qiongyu Chen, Yan Zhao, Yonghong Zhang, Jianbo Zhang, Wenshu Lu, Chih-Hao Chang, and Shisong Jiang

     

    HSC-derived fatty acid oxidation in steady-state and stressed hematopoiesis., Jayna J Mistry, Kristian Bowles, and Stuart A Rushworth

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    HSC-derived fatty acid oxidation in steady-state and stressed hematopoiesis., Jayna J Mistry, Kristian Bowles, and Stuart A Rushworth

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    Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection., Shawn A Abeynaike, Tridu R Huynh, Abeera Mehmood, Teha Kim, Kayla Frank, Kefei Gao, Cristina Zalfa, Angel Gandarilla, Leonard D. Shultz, and Silke Paust

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    Humanized mouse models for immuno-oncology research., Jane Chuprin, Hannah Buettner, Mina O Seedhom, Dale L Greiner, James G. Keck, Fumihiko Ishikawa, Leonard D. Shultz, and Michael A Brehm

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    Human Patient-Derived Brain Tumor Models to Recapitulate Ependymoma Tumor Vasculature., Min D Tang-Schomer, Markus J Bookland, Jack E Sargent, and Taylor N Jackvony

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    ICLAS LAQ Network for the Promotion of Animal Quality in Research., Patri Vergara, Gregory Ballard, Cynthia Besch-Williford, Nobuhito Hayashimoto, Cynthia Pekow, Ana Perez, Katja Schmidt, William Shek, Martin Toft, and Atsushi Yoshiki

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    Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation., Kelsey H Elliott, Sai K Balchand, Christian Louis Bonatto Paese, Ching-Fang Chang, Yanfen Yang, Kari M Brown, Daniel T Rasicci, Hao He, Konrad Thorner, Praneet Chaturvedi, Stephen A. Murray, Jing Chen, Aleksey Porollo, Kevin A Peterson, and Samantha A Brugmann

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    Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation., Kelsey H Elliott, Sai K Balchand, Christian Louis Bonatto Paese, Ching-Fang Chang, Yanfen Yang, Kari M Brown, Daniel T Rasicci, Hao He, Konrad Thorner, Praneet Chaturvedi, Stephen A. Murray, Jing Chen, Aleksey Porollo, Kevin A Peterson, and Samantha A Brugmann

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    Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response., Joshua C Doloff, Minglin Ma, Atieh Sadraei, Hok Hei Tam, Shady Farah, Jennifer Hollister-Lock, Arturo J Vegas, Omid Veiseh, Victor M Quiroz, Amanda Rakoski, Stephanie Aresta-DaSilva, Andrew R Bader, Marissa Griffin, Gordon C Weir, Michael A Brehm, Leonard D. Shultz, Robert Langer, Dale L Greiner, and Daniel G Anderson

     

    Identification of structural variants leading to non-reference gene structure, Grace Koo

     

    Identification of TCR repertoires in asymptomatic COVID-19 patients by single-cell T-cell receptor sequencing., Han Bai, Junpeng Ma, Weikang Mao, Xuan Zhang, Yijun Nie, Jingcan Hao, Xiaorui Wang, Hongyu Qin, Qiqi Zeng, Fang Hu, Xin Qi, Xiaobei Chen, Dong Li, Binghong Zhang, Bingyin Shi, and Chengsheng Zhang

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    Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy., K White, K Connor, M Meylan, A Bougoüin, M Salvucci, F Bielle, A C O'Farrell, K Sweeney, L Weng, G Bergers, P Dicker, D M Ashley, E S Lipp, J T Low, J Zhao, P Wen, R Prins, M Verreault, A Idbaih, A Biswas, J H M Prehn, D Lambrechts, I Arijs, F Lodi, G Dilcan, M Lamfers, S Leenstra, F Fabro, I Ntafoulis, J M Kros, J Cryan, F Brett, E Quissac, A Beausang, S MacNally, P O'Halloran, J Clerkin, O Bacon, A Kremer, R T Chi Yen, Frederick S Varn, Roel G W Verhaak, C Sautès-Fridman, W H Fridman, and A T Byrne

     

    Identifying core and accessory essential genes of genetically diverse Staphylococcus epidermidis strains with genome-wide CRISPRi screens, Sierra Mellor

     

    Identifying signatures of mutational mechanisms for tandem duplications found in breast cancers, Leila Shepard

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    Identifying susceptibility genes for essential hypertension by transcriptome-wide association study., Lu-Jie Huang, Qiao-Xia Zhang, Robert K Valenzuela, Jia-Chen Xu, Fang Yan, and Jie Ma

     

    Identifying the Genetic Basis of Immune Checkpoint Inhibitor Induced Type 1 Diabetes, Tobias Emge

     

    Identifying the gut microbe gene products that induce human immune cells to upregulate interferon-gamma production, Veronica Perdomo

     

    Identifying Transcriptomic Signatures to Mediate Causal Effect of Genotype on Alzheimer's Disease, Simran Kaur

     

    IL-6 Monoclonal Antibody Elsilimomab Inhibits Bone Marrow Stromal Cell Senescence Induced by Dnmt3a-Mutant Clonal Hematopoiesis, David Bernal

     

    Immunomodulatory metabolite production by commensal microbiome bacteria, Christian Badawi

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    Immunosuppressive reprogramming of neutrophils by lung mesenchymal cells promotes breast cancer metastasis., Zheng Gong, Qing Li, Jiayuan Shi, Peishan Li, Li Hua, Leonard D. Shultz, and Guangwen Ren

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    Improvement of Long COVID symptoms over one year., Carlos R Oliveira, Leonard A Jason, Derya Unutmaz, Lucinda Bateman, and Suzanne D Vernon

     

    Improving racial diversity in the genomics workforce: An examination of challenges and opportunities., Catherine Wicklund, Kunal Sanghavi, Bernice Coleman, Katherine Johansen Taber, Jacquelyn Y Taylor, Kathryn C Asalone, and Sarah Beachy

     

    Individual differences in cognitive resilience to AD are not explained by variation in neurogenesis in the AD-BXDs, Emily Kim

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    Inferring cell-type-specific causal gene regulatory networks during human neurogenesis., Nil Aygün, Dan Liang, Wesley L Crouse, Gregory R Keele, Michael I Love, and Jason L Stein

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    Information-theory analysis of mouse string-pulling agrees with Fitts's Law: Increasing task difficulty engages multiple sensorimotor modalities in a dual oscillator behavior., Pardeepak S Sandhu, Behroo Mirza Agha, Samsoon Inayat, Surjeet Singh, Hardeep S Ryait, Majid H Mohajerani, and Ian Q Whishaw

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    Inherited deletion of 9p22.3-p24.3 and duplication of 18p11.31-p11.32 associated with neurodevelopmental delay: Phenotypic matching of involved genes., Naser Ajami, Mohammad Amin Kerachian, Mehran Beiraghi Toosi, Farah Ashrafzadeh, Susan Hosseini, Peter N Robinson, and Mohammad Reza Abbaszadegan

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    Integrated DNA Copy Number and Expression Profiling Identifies IGF1R as a Prognostic Biomarker in Pediatric Osteosarcoma., Aaron M Taylor, Jiayi M Sun, Alexander Yu, Horatiu Voicu, Jianhe Shen, Donald A Barkauskas, Timothy J Triche, Julie M Gastier-Foster, Tsz-Kwong Man, and Ching C Lau

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    Integrative deep learning analysis improves colon adenocarcinoma patient stratification at risk for mortality., Jie Zhou, Ali Foroughi Pour, Hany Deirawan, Fayez Daaboul, Thazin Nwe Aung, Rafic Beydoun, Fahad Shabbir Ahmed, and Jeffrey Chuang

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    Intergenomic and epistatic interactions control free radical mediated pancreatic β-cell damage., Jing Chen, Renhua Li, Sarah Knapp, Guizhi Zhu, Robert L Whitener, Edward H. Leiter, and Clayton E Mathews

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    Introduction to Mouse Pathology, Jerrold M. Ward, Peter Vogel, and John P Sundberg

     

    Investigating a Genetically Diverse Mouse Model for Vasculitis, Emma Hendrix

     

    Investigating Loss of Methylation at the BRCA1 Promoter as a Mechanism of Chemoresistance, Benjamin C. Brim

     

    Investigating the endometrial microenvironment via characterization of progenitor-like epithelial cells and fibroblastic response to trophectoderm secretions, Colt Crain

     

    Investigating the Infralimbic-Amygdala Circuit During Fear Extinction Learning, Grace O'Brien

     

    Investigating the Oocyte DNA Damage Response after Radiation Exposure, Michelle Seeler

     

    Investigating the role of potential PRDM9 interactors FUS and DEK in recombination hotspot activation., Adel Misherghi

     

    Investigation of Metabolic Changes for Early Detection of Alzheimer's Disease, Megan Sherally Mathews

     

    In vitro validation of inhibitors targeting TCF-4 and beta catenin interaction in WNT-activated tumors, Cynthia Martucci

     

    In vivo activity of the dual SYK/FLT3 inhibitor TAK-659 against pediatric acute lymphoblastic leukemia xenografts., Keira Hughes, Kathryn Evans, Eric J Earley, Christopher M Smith, Stephen W Erickson, Timothy M Stearns, Vivek M. Philip, Steven Neuhauser, Jeffrey Chuang, Emily L Jocoy, Carol J Bult, Beverly A Teicher, Malcolm A Smith, and Richard B Lock

     

    In Vivo Imaging of Bone Marrow Long-Chain Fatty Acid Uptake., Jayna J Mistry and Stuart A Rushworth

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    ISSCR standards for the use of human stem cells in basic research., Tenneille E Ludwig, Peter W Andrews, Ivana Barbaric, Nissim Benvenisty, Anita Bhattacharyya, Jeremy M Crook, Laurence M Daheron, Jonathan S Draper, Lyn E Healy, Meritxell Huch, Maneesha S Inamdar, Kim B Jensen, Andreas Kurtz, Madeline A Lancaster, Prisca Liberali, Matthias P Lutolf, Christine L Mummery, Martin Pera, Yoji Sato, Noriko Shimasaki, Austin G Smith, Jihwan Song, Claudia Spits, Glyn Stacey, Christine A Wells, Tongbiao Zhao, and Jack T Mosher

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    JACKIE: Fast Enumeration of Genome-Wide Single- and Multicopy CRISPR Target Sites and Their Off-Target Numbers., Jacqueline Jufen Zhu and Albert Cheng

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    KG-Hub-building and exchanging biological knowledge graphs., J Harry Caufield, Tim Putman, Kevin Schaper, Deepak R Unni, Harshad Hegde, Tiffany J Callahan, Luca Cappelletti, Sierra A T Moxon, Vida Ravanmehr, Seth Carbon, Lauren E Chan, Katherina Cortes, Kent A Shefchek, Glass Elsarboukh, Jim Balhoff, Tommaso Fontana, Nicolas Matentzoglu, Richard M Bruskiewich, Anne E Thessen, Nomi L Harris, Monica C Munoz-Torres, Melissa A Haendel, Peter N Robinson, Marcin P Joachimiak, Christopher J Mungall, and Justin T Reese

     

    Landscape of genetic variants in sporadic meningiomas captured with clinical genomics., Nathan K Leclair, Erica Shen, Qian Wu, Leo Wolansky, Kevin Becker, Lei Li, and Ketan R Bulsara

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    Large-Scale CRISPRi and Transcriptomics of Staphylococcus epidermidis Identify Genetic Factors Implicated in Lifestyle Versatility., Michelle Spoto, Johanna P. Riera Puma, Elizabeth Fleming, Changhui Guan, Yvette Ondouah Nzutchi, Dean Kim, and Julia Oh

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    Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice., T M O'Shea, Y Ao, S Wang, A L Wollenberg, J H Kim, R A Ramos Espinoza, Anne M. Czechanski, Laura G. Reinholdt, T J Deming, and M V Sofroniew

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    Leveraging genetic diversity in mice to inform individual differences in brain microstructure and memory., Thomas J Murdy, Amy R Dunn, Surjeet Singh, Maria Telpoukhovskaia, Shanrong Zhang, Jacqueline K White, Itamar Kahn, Marcelo Febo, and Catherine Kaczorowski

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    Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice., Randy Strong, Richard A Miller, Catherine J Cheng, James F Nelson, Jonathan Gelfond, Shailaja Kesaraju Allani, Vivian Diaz, Angela Olsen Dorigatti, Jonathan Dorigatti, Elizabeth Fernandez, Andrzej Galecki, Brett Ginsburg, Karyn L Hamilton, Martin A Javors, Kerry Kornfeld, Matt Kaeberlein, Suja Kumar, David B Lombard, Marisa Lopez-Cruzan, Benjamin F Miller, Peter Rabinovitch, Peter C. Reifsnyder, Nadia Rosenthal, Molly A. Bogue, Adam B Salmon, Yousin Suh, Eric Verdin, Herbert Weissbach, John Newman, Francesca Maccchiarini, and David E. Harrison

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    Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAF, Ze-Yan Zhang, Yingwen Ding, Ravesanker Ezhilarasan, Tenzin Lhakhang, Qianghu Wang, Jie Yang, Aram S Modrek, Hua Zhang, Aristotelis Tsirigos, Andrew Futreal, Giulio F Draetta, Roel G W Verhaak, and Erik P Sulman

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    Lipid alternations in the plasma of COVID-19 patients with various clinical presentations., Xiao Liang, Xin Qi, Jin Yang, Xiaorui Wang, Hongyu Qin, Fang Hu, Han Bai, Yixin Li, Chengsheng Zhang, and Bingyin Shi

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    Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells., Zheng Gong, Qing Li, Jiayuan Shi, Edison Liu, Leonard D. Shultz, and Guangwen Ren

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    Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin., Tara R Price, Donnie S Stapleton, Kathryn L Schueler, Marie K Norris, Brian W Parks, Brian S Yandell, Gary Churchill, William L Holland, Mark P Keller, and Alan D Attie

     

    Longitudinal investigation of the gut microbiome in a Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) cohort, Stefanie Moncayo

     

    Longitudinal Molecular Characterization of Oligodendrogliomas, Gordon Y. Ye

     

    Long-Read Sequencing Identifies Structural Variants That Alter Gene Expression In Diverse Mice, Varun Moser

     

    Long-term effects of canagliflozin treatment on the skeleton of aged UM-HET3 mice., Gozde Yildirim, Edmara T P Bergamo, Sher Bahadur Poudel, Ryan R Ruff, Manisha Dixit, Bin Hu, Dindo Q Mijares, Lukasz Witek, Carolyn Chlebek, David E Harrison, Randy Strong, Richard A Miller, Warren Ladiges, Timothy G Bromage, Clifford J Rosen, and Shoshana Yakar

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    Loss of circSRY reduces γH2AX level in germ cells and impairs mouse spermatogenesis., Yanze Song, Min Chen, Yingfan Zhang, Jiayi Li, Bowen Liu, Na Li, Min Chen, Miaomiao Qiao, Nan Wang, Yuanwei Cao, Shan Lu, Jian Chen, Wen Sun, Fei Gao, and Haoyi Wang

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    Loss of Pex1 in Inner Ear Hair Cells Contributes to Cochlear Synaptopathy and Hearing Loss., Stephanie A Mauriac, Thibault Peineau, Aamir Zuberi, Cathleen Lutz, and Gwénaëlle S G Géléoc

     

    Loss of resilience contributes to detrusor underactivity in advanced age., Ramalakshmi Ramasamy, Dylan Baker, Fouad Lemtiri-Chlieh, Dawn A Rosenberg, Eric Woon, Iman M Al-Naggar, Cara C Hardy, Eric S Levine, George A Kuchel, Jenna M Bartley, and Phillip P Smith

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    LUMOS - Low and Intermediate Grade Glioma Umbrella Study of Molecular Guided TherapieS at relapse: Protocol for a pilot study., Benjamin Y Kong, Hao-Wen Sim, Anna K Nowak, Sonia Yip, Elizabeth H Barnes, Bryan W Day, Michael E Buckland, Roel G W Verhaak, Terrance Johns, Cleo Robinson, Marc A Thomas, Tindaro Giardina, Zarnie Lwin, Andrew M Scott, Jonathon Parkinson, Rosalind Jeffree, Richard de Abreu Lourenco, Elizabeth J Hovey, Lawrence M Cher, Ganessan Kichendasse, Mustafa Khasraw, Merryn Hall, Emily Tu, Benhur Amanuel, Eng-Siew Koh, and Hui K Gan

     

    Maintenance of Human Primordial Germ Cell-Like Cells in a Long-Term Culture System., Joanna J Gell and Toshi Shioda

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    Mako: A Graph-based Pattern Growth Approach to Detect Complex Structural Variants., Jiadong Lin, Xiaofei Yang, Walter Kosters, Tun Xu, Yanyan Jia, Songbo Wang, Qihui Zhu, Mallory Ryan, Li Guo, Chengsheng Zhang, The Human Genome Structural Variation Consortium, Charles Lee, Scott E Devine, Evan E Eichler, and Kai Ye

     

    Mapping the Symptoms of Alzheimer’s Disease and its Subtypes to Mammalianand Human Phenotype Ontology Terms to Enhance Cross Species Analysis, Sarah Stofel

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    MATR3 P154S knock-in mice do not exhibit motor, muscle or neuropathologic features of ALS., Marissa Dominick, Nicole Houchins, Vinisha Venugopal, Aamir Zuberi, Cathleen Lutz, Bessie Meechooveet, Kendall Van Keuren-Jensen, Robert Bowser, and David X Medina

     

    Mechanical Washing Prevents Transmission of Bacterial, Viral, and Protozoal Murine Pathogens from Cages., Amanda C Ritter, Rodolfo J Ricart Arbona, Anthony J Mourino, Michael B Palillo, Mert Aydin, James R Fahey, and Neil S Lipman

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    Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies, Michael W Baughn, Ze'ev Melamed, Jone López-Erauskin, Melinda S Beccari, Karen Ling, Aamir Zuberi, Maximiliano Presa, Elena Gonzalo-Gil, Roy Maimon, Sonia Vazquez-Sanchez, Som Chaturvedi, Mariana Bravo-Hernández, Vanessa Taupin, Stephen Moore, Jonathan W Artates, Eitan Acks, I Sandra Ndayambaje, Ana R Agra de Almeida Quadros, Paayman Jafar-Nejad, Frank Rigo, C Frank Bennett, Cathleen Lutz, Clotilde Lagier-Tourenne, and Don W Cleveland

     

    Meiotic drive in house mice: mechanisms, consequences, and insights for human biology., Uma P Arora and Beth L Dumont

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    Mendelian gene identification through mouse embryo viability screening., Pilar Cacheiro, Carl Henrik Westerberg, Jesse Mager, Mary E Dickinson, Lauryl M J Nutter, Violeta Muñoz-Fuentes, Chih-Wei Hsu, Ignatia B Van den Veyver, Ann M Flenniken, Colin McKerlie, Stephen A Murray, Lydia Teboul, Jason D Heaney, K C Kent Lloyd, Louise Lanoue, Robert E Braun, Jacqueline K White, Amie K Creighton, Valerie Laurin, Ruolin Guo, Dawei Qu, Sara Wells, James Cleak, Rosie Bunton-Stasyshyn, Michelle Stewart, Jackie Harrisson, Jeremy Mason, Hamed Haseli Mashhadi, Helen Parkinson, Ann-Marie Mallon, International Mouse Phenotyping Consortium, Genomics England Research Consortium, and Damian Smedley

     

    Metabolic Control of T follicular helper cell polarization, Anthony Mendoza

     

    Metabolic regulation of CXCR5 expression in T cells via the kynurenine pathway, Thi-Tina N. Nguyen

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    Metabolic Responses of Normal Rat Kidneys to a High Salt Intake., Satoshi Shimada, Brian Hoffmann, Chun Yang, Theresa Kurth, Andrew S Greene, Mingyu Liang, Ranjan K Dash, and Allen W Cowley

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    Metformin is associated with reduced COVID-19 severity in patients with prediabetes., Lauren E Chan, Elena Casiraghi, Bryan Laraway, Ben D Coleman, Hannah Blau, Adnin Zaman, Nomi L Harris, Kenneth Wilkins, Blessy Antony, Michael Gargano, Giorgio Valentini, David Sahner, Melissa Haendel, Peter N Robinson, Carolyn Bramante, and Justin Reese

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    Microbial glutamate metabolism predicts intravenous cocaine self-administration in diversity outbred mice., Thi Dong Binh Tran; Hoan Nguyen; Erica Sodergren Weinstock; Center for Systems Neurogenetics of Addiction, The Jackson Laboratory; Price E Dickson; Susan N Wright; Vivek M. Philip; George M. Weinstock; Elissa J Chesler; Yanjiao Zhou; and Jason A. Bubier

     

    Microbiome modulates immunotherapy response in cutaneous squamous cell carcinoma, Anita Y Voigt, Andrew Walter, Timothy Young, John P Graham, Bruna M. Batista Bittencourt, Alvero de Mingo Pulido, Karol Prieto, Kenneth Y. Tsai, John P Sundberg, and Julia Oh

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    Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes., Matthew C Funsten, Leonid A Yurkovetskiy, Andrey Kuznetsov, Derek Reiman, Camilla H F Hansen, Katharine I Senter, Jean Lee, Jeremy Ratiu, Shiva Dahal-Koirala, Dionysios A Antonopoulos, Gary M Dunny, Ludvig M Sollid, David Serreze, Aly A Khan, and Alexander V Chervonsky

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    Misregulation of mitochondria-lysosome contact dynamics in Charcot-Marie-Tooth Type 2B disease Rab7 mutant sensory peripheral neurons, Yvette C. Wong, Nirupa D. Jayaraj, Tayler B. Belton, George C. Shum, Hannah E. Ball, Dongjun Ren, Abby Tadenev, Dimitri Krainc, Robert W. Burgess, and Daniela M. Menichella

     

    Modeling hyperopia in Prss56glcr4 mice: Molecular comparativ analysis with Mfrprd6 and QTL mapping of axial length alterations, Jessica Guzman

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    Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits., Sanjarbek Hudaiberdiev, D Leland Taylor, Wei Song, Narisu Narisu, Redwan M Bhuiyan, Henry J Taylor, Xuming Tang, Tingfen Yan, Amy J Swift, Lori L Bonnycastle, Diamante Consortium, Shuibing Chen, Michael L. Stitzel, Michael R Erdos, Ivan Ovcharenko, and Francis S Collins

     

    Modeling the dynamics of BRCA1 promoter methylation relevant to triple-negative breast cancer, Anthony Woodruff

     

    Modifiers of Charcot-Marie-Tooth Disease Type 1A Neuropathy in the Sox10/Egr2 Networ, Leeza Kopaeva

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    Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia., Eric Wang, Jose Mario Bello Pineda, Won Jun Kim, Sisi Chen, Jessie Bourcier, Maximilian Stahl, Simon J Hogg, Jan Phillipp Bewersdorf, Cuijuan Han, Michael E Singer, Daniel Cui, Caroline E Erickson, Steven M Tittley, Alexander V Penson, Katherine Knorr, Robert F Stanley, Jahan Rahman, Gnana Krishnamoorthy, James A Fagin, Emily Creger, Elizabeth McMillan, Chi-Ching Mak, Matthew Jarvis, Carine Bossard, Darrin M Beaupre, Robert K Bradley, and Omar Abdel-Wahab

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    Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia., Eric Wang, Jose Mario Bello Pineda, Won Jun Kim, Sisi Chen, Jessie Bourcier, Maximilian Stahl, Simon J Hogg, Jan Phillipp Bewersdorf, Cuijuan Han, Michael E Singer, Daniel Cui, Caroline E Erickson, Steven M Tittley, Alexander V Penson, Katherine Knorr, Robert F Stanley, Jahan Rahman, Gnana Krishnamoorthy, James A Fagin, Emily Creger, Elizabeth McMillan, Chi-Ching Mak, Matthew Jarvis, Carine Bossard, Darrin M Beaupre, Robert K Bradley, and Omar Abdel-Wahab

     

    Molecular Approaches to Increase Stroke Resiliency Using Human Pluripotent Stem Cell- Derived Neurons, Elise MacDonald

     

    Molecular Mechanisms of ARID5B-Mediated Genetic Susceptibility to Acute Lymphoblastic Leukemia., Xujie Zhao, Maoxiang Qian, Charnise Goodings, Yang Zhang, Wenjian Yang, Ping Wang, Beisi Xu, Cheng Tian, Ching-Hon Pui, Stephen P Hunger, Elizabeth A Raetz, Meenakshi Devidas, Mary V Relling, Mignon L Loh, Daniel Savic, Chunliang Li, and Jun J Yang

     

    Morphological analysis of cutaneous T-cell lymphoma unaging using attention-based deep learning, Amaris Huang

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    Mouse Genetic Nomenclature: The Underpinning of Mouse Genetics, John P Sundberg, Dale A. Begley, Melissa L. Berry, Michelle N Perry, David R. Shaw, and Paul N. Schofield

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    Mouse models for immuno-oncology., Marcus Bosenberg, Edison Liu, Chun I. Yu, and Karolina Palucka

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    Mouse Phenome Database: towards a more FAIR-compliant and TRUST-worthy data repository and tool suite for phenotypes and genotypes., Molly A. Bogue, Robyn L Ball, Vivek M. Philip, David O Walton, Matthew H Dunn, Georgi Kolishovski, Anna Lamoureux, Matthew Gerring, Hongping Liang, Jake Emerson, Timothy M Stearns, Hao He, Gaurab Mukherjee, John Bluis, Sejal Desai, Beth A. Sundberg, Beena Kadakkuzha, Govindarajan Kunde-Ramamoorthy, and Elissa J Chesler

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    Multidimensional single-cell analysis of human peripheral blood reveals characteristic features of the immune system landscape in aging and frailty., Oscar Junhong Luo, Wen Lei, Guodong Zhu, Zhiyao Ren, Yudai Xu, Chanchan Xiao, Hongyi Zhang, Junxiang Cai, Zhiping Luo, Lijuan Gao, Jun Su, Lei Tang, Wei Guo, Huanxing Su, Zhang-Jin Zhang, Evandro Fei Fang, Yijun Ruan, Sean Xiao Leng, Zhenyu Ju, Huiling Lou, Junling Gao, Nan Peng, Jie Chen, Zhijun Bao, Feng Liu, and Guobing Chen

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    Multi-omics analysis identifies drivers of protein phosphorylation., Tian Zhang, Gregory R Keele, Isabela Gerdes Gyuricza, Matthew J Vincent, Catherine Brunton, Timothy A Bell, Pablo Hock, Ginger D Shaw, Steven C. Munger, Fernando Pardo-Manuel de Villena, Martin T Ferris, Joao A Paulo, Steven P Gygi, and Gary Churchill

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    Multi-'omics of gut microbiome-host interactions in short- and long-term myalgic encephalomyelitis/chronic fatigue syndrome patients., Ruoyun Xiong, Courtney Gunter, Elizabeth Fleming, Suzanne D Vernon, Lucinda Bateman, Derya Unutmaz, and Julia Oh

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    Multiplex immunofluorescence-guided laser capture microdissection for spatial transcriptomics of metastatic melanoma tissues., Jan Martinek, Te-Chia Wu, Lili Sun, Jianan Lin, Kyung In Kim, Florentina Marches, Paul Robson, Joshy George, and Karolina Palucka

     

    Multi-species convergent functional genomics analysis of substance usedisorders reveals shared genes in poly-drug use, Bailey E. West

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    MYC regulates a pan-cancer network of co-expressed oncogenic splicing factors., Laura M Urbanski, Mattia Brugiolo, SungHee Park, Brittany Lynn Angarola, Nathan Leclair, Marina Yurieva, Phil Palmer, Sangram Keshari Sahu, and Olga Anczuków

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    Myocardial Biomechanics and the Consequent Differentially Expressed Genes of the Left Atrial Ligation Chick Embryonic Model of Hypoplastic Left Heart Syndrome., S Samaneh Lashkarinia, Wei Xuan Chan, Efthymios Motakis, Sheldon Ho, Hummaira Banu Siddiqui, Mervenur Coban, Bortecine Sevgin, Kerem Pekkan, and Choon Hwai Yap

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    Myostatin: A Skeletal Muscle Chalone., Se-Jin Lee

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    Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma., Lingxiang Wu, Wei Wu, Junxia Zhang, Zheng Zhao, Liangyu Li, Mengyan Zhu, Min Wu, Fan Wu, Fengqi Zhou, Yuxin Du, Rui-Chao Chai, Wei Zhang, Xiaoguang Qiu, Quanzhong Liu, Ziyu Wang, Jie Li, Kening Li, Apeng Chen, Yinan Jiang, Xiangwei Xiao, Han Zou, Rashmi Srivastava, Tingting Zhang, Yun Cai, Yuan Liang, Bin Huang, Ruohan Zhang, Fan Lin, Lang Hu, Xiuxing Wang, Xu Qian, Sali Lv, Baoli Hu, Siyuan Zheng, Zhibin Hu, Hongbing Shen, Yongping You, Roel G W Verhaak, Tao Jiang, and Qianghu Wang

     

    Neoteny in Mice: The effects of PDGFRα+ cell depletion during postnatal growth, Raheem Khadour

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    NetAct: a computational platform to construct core transcription factor regulatory networks using gene activity., Kenong Su, Ataur Katebi, Vivek Kohar, Benjamin Clauss, Danya Gordin, Zhaohui S Qin, Radha Krishna Murthy Karuturi, Sheng Li, and Mingyang Lu

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    Neurobehavioral deficits of mice expressing a low level of G127V mutant frataxin., Daniel Fil, Robbie L Conley, Aamir Zuberi, Cathleen Lutz, Terry Gemelli, Marek Napierala, and Jill S Napierala

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    Neuronal diversity can improve machine learning for physics and beyond., Anshul Choudhary, Anil Radhakrishnan, John F Lindner, Sudeshna Sinha, and William L Ditto

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    New insight into the causes, consequences, and correction of hematopoietic stem cell aging., Els Mansell, Dawn S Lin, Stephen J Loughran, Michael D Milsom, and Jennifer J. Trowbridge

     

    New mouse models with hypomorphic SUMF1 variants mimic attenuated forms of multiple sulfatase deficiency., Nicolina Cristina Sorrentino, Maximiliano Presa, Sergio Attanasio, Vincenzo Cacace, Martina Sofia, Aamir Zuberi, Jennifer L Ryan, Somdatta Ray, Igor Petkovic, Karthikeyan Radhakrishnan, Lars Schlotawa, Andrea Ballabio, Cathleen Lutz, and Nicola Brunetti-Pierri

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    NOD-scid IL2rγnull mice lacking TLR4 support human immune system development and the study of human-specific innate immunity., Ken-Edwin Aryee, Leonard D. Shultz, Lisa M Burzenski, Dale L Greiner, and Michael A Brehm

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    Novel skewed usage of B-cell receptors in COVID-19 patients with various clinical presentations., Junpeng Ma, Han Bai, Tian Gong, Weikang Mao, Yijun Nie, Xuan Zhang, Yanyan Da, Xiaorui Wang, Hongyu Qin, Qiqi Zeng, Fang Hu, Xin Qi, Bingyin Shi, and Chengsheng Zhang

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    NUTMEG: A randomized phase II study of nivolumab and temozolomide versus temozolomide alone in newly diagnosed older patients with glioblastoma., Hao-Wen Sim, Luke Wachsmuth, Elizabeth H Barnes, Sonia Yip, Eng-Siew Koh, Merryn Hall, Ross Jennens, David M Ashley, Roel G W Verhaak, Amy B Heimberger, Mark A Rosenthal, Elizabeth J Hovey, Benjamin M Ellingson, Annette Tognela, Hui K Gan, Helen Wheeler, Michael Back, Kerrie L McDonald, Anne Long, Katharine Cuff, Stephen Begbie, Craig Gedye, Anna Mislang, Hien Le, Margaret O Johnson, Benjamin Y Kong, John R Simes, Zarnie Lwin, and Mustafa Khasraw

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    On the dependent recognition of some long zinc finger proteins., Zheng Zuo, Timothy Billings, Michael Walker, Petko M. Petkov, Polly M Fordyce, and Gary D Stormo

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    Ontologizing health systems data at scale: making translational discovery a reality., Tiffany J Callahan, Adrianne L Stefanski, Jordan M Wyrwa, Chenjie Zeng, Anna Ostropolets, Juan M Banda, William A Baumgartner, Richard D Boyce, Elena Casiraghi, Ben D Coleman, Janine H Collins, Sara J Deakyne Davies, James A Feinstein, Asiyah Y Lin, Blake Martin, Nicolas A Matentzoglu, Daniella Meeker, Justin Reese, Jessica Sinclair, Sanya B Taneja, Katy E Trinkley, Nicole A Vasilevsky, Andrew E Williams, Xingmin A Zhang, Joshua C Denny, Patrick B Ryan, George Hripcsak, Tellen D Bennett, Melissa A Haendel, Peter N Robinson, Lawrence E Hunter, and Michael G Kahn

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    Open drug discovery in Alzheimer's disease., Alison D Axtman, Paul E Brennan, Tristan Frappier-Brinton, Ranjita Betarbet, Gregory W. Carter, Haian Fu, Opher Gileadi, Anna K Greenwood, Karina Leal, Frank M Longo, Lara M Mangravite, Aled M Edwards, Allan I Levey, and The Emory-Sage-SGC TREAT-AD Center.

     

    Optimizing the morphological characterization of single hippocampal neurons using Patch-seq, Annie Williams

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    Overview of triple negative breast cancer prognostic signatures in the context of data science-driven clinico-genomics research., Enrico Capobianco

     

    Papillary thyroid cancer immune phenotypes via tumor-infiltrating lymphocyte spatial analysis., Myungwoo Nam, Woojung Yang, Hye Sung Kim, Jewel Park, Gahee Park, Sukjun Kim, Sanghoon Song, Chan-Young Ock, Victor G Wang, Jeffrey Chuang, and Young Kwang Chae

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    Pathology of genetically engineered and other mutant mice, John P Sundberg, Peter Vogel, and Jerrold M. Ward

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    PDCM Finder: an open global research platform for patient-derived cancer models., Zinaida Perova, Mauricio Martinez, Tushar Mandloi, Federico Lopez Gomez, Csaba Halmagyi, Alex Follette, Jeremy Mason, Steven Neuhauser, Dale A. Begley, Debra M Krupke, Carol J Bult, Helen Parkinson, and Tudor Groza

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    Performance Modeling of Scalable Resource Allocations with the Imperial PEPA Compiler, William S. Sanders, Srishti Srivastava, and Ionana Banicescu

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    Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease., Sebastiaan De Schepper, Judy Z Ge, Gerard Crowley, Laís S S Ferreira, Dylan Garceau, Christina E Toomey, Dimitra Sokolova, Javier Rueda-Carrasco, Sun-Hye Shin, Jung-Seok Kim, Thomas Childs, Tammaryn Lashley, Jemima J Burden, Michael Sasner, Carlo Sala Frigerio, Steffen Jung, and Soyon Hong

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    Phenopacket-tools: Building and validating GA4GH Phenopackets., Daniel Danis, Julius O B Jacobsen, Alex H Wagner, Tudor Groza, Martha A Beckwith, Lauren Rekerle, Leigh Carmody, Justin Reese, Harshad Hegde, Markus S Ladewig, Berthold Seitz, Monica Munoz-Torres, Nomi L Harris, Jordi Rambla, Michael Baudis, Christopher J Mungall, Melissa A Haendel, and Peter N Robinson

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    Phenotype-aware prioritisation of rare Mendelian disease variants., Catherine Kelly, Anita Szabo, Nikolas Pontikos, Gavin Arno, Peter N Robinson, Jules O B Jacobsen, Damian Smedley, and Valentina Cipriani

     

    Phenotypic trait variation in the North American Tragopogon allopolyploid complex., Ingrid E Jordon-Thaden, Jonathan P Spoelhof, Lyderson Facio Viccini, Joseph Combs, Francisco Gomez, Imari Walker, Douglas E Soltis, and Pamela S Soltis

     

    Phenotyping mice with skin, hair, or nail abnormalities: A systematic approach and methodologies from simple to complex., John P Sundberg and Robert H Rice

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    Pkhd1, Chaozhe Yang, Naoe Harafuji, Ljubica Caldovic, Weiying Yu, Ravindra Boddu, Surajit Bhattacharya, Hayk Barseghyan, Heather Gordish-Dressman, Oded Foreman, Zsuzsa Bebok, Eva M Eicher, and Lisa M Guay-Woodford

     

    Plasticity Requirements in IL-to-BLA Circuitry During Extinction Learning, Allison Velie

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    PLS3 missense variants affecting the actin-binding domains cause X-linked congenital diaphragmatic hernia and body-wall defects., Florence Petit, Mauro Longoni, Julie Wells, Richard S. Maser, Eric L Bogenschutz, Matthew J Dysart, Hannah T M Contreras, Frederic Frénois, Barbara R Pober, Robin D Clark, Philip F Giampietro, Hilger H Ropers, Hao Hu, Maria Loscertales, Richard Wagner, Xingbin Ai, Harrison Brand, Anne-Sophie Jourdain, Marie-Ange Delrue, Brigitte Gilbert-Dussardier, Louise Devisme, Boris Keren, David J McCulley, Lu Qiao, Rebecca Hernan, Julia Wynn, Tiana M Scott, Daniel G Calame, Zeynep Coban-Akdemir, Patricia Hernandez, Andres Hernandez-Garcia, Hagith Yonath, James R Lupski, Yufeng Shen, Wendy K Chung, Daryl A Scott, Carol J Bult, Patricia K Donahoe, and Frances A High

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    'Poisoning' of the transcriptome by ultraconserved elements., Nathan Leclair and Olga Anczuków

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    Polygenic influences on the behavioral effects of alcohol withdrawal in a mixed-ancestry population from the collaborative study on the genetics of alcoholism (COGA)., Chelsie E Benca-Bachman, Jason A. Bubier, Rameez A Syed, Pamela N Romero Villela, and Rohan H C Palmer

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    Possibilities and pitfalls of practitioners in trying to apply change theory as viewed through the lens of Reinholz, White, and Andrews “Change theory in STEM higher education: a systematic review, Melissa Elben-Zayas, Laura J Muller, and Janet Russell

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    Post-exertional malaise among people with long COVID compared to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)., Suzanne D Vernon, Megan Hartle, Karen Sullivan, Jennifer Bell, Saeed Abbaszadeh, Derya Unutmaz, and Lucinda Bateman

     

    Precision mouse models of Yars/dominant intermediate Charcot-Marie-Tooth disease type C and Sptlc1/hereditary sensory and autonomic neuropathy type 1., Timothy J Hines, Abigail L D Tadenev, Museer A Lone, Courtney L Hatton, Inseyah Bagasrawala, Morgane G. Stum, Kathy E Miers, Thorsten Hornemann, and Robert W. Burgess

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    Predictable Fluctuations in Excitatory Synaptic Strength Due to Natural Variation in Presynaptic Firing Rate., Naixin Ren, Ganchao Wei, Abed Ghanbari, and Ian H Stevenson

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    Predictive models of long COVID., Blessy Antony, Hannah Blau, Elena Casiraghi, Johanna J Loomba, Tiffany J Callahan, Bryan J Laraway, Kenneth J Wilkins, Corneliu C Antonescu, Giorgio Valentini, Andrew E Williams, Peter N Robinson, Justin T Reese, T M Murali, and on behalf of the N3C consortium.

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    Prenatal phenotyping: A community effort to enhance the Human Phenotype Ontology., Ferdinand Dhombres, Patricia Morgan, Bimal P Chaudhari, Isabel Filges, Teresa N Sparks, Pablo Lapunzina, Tony Roscioli, Umber Agarwal, Shagun Aggarwal, Claire Beneteau, Pilar Cacheiro, Leigh Carmody, Sophie Collardeau-Frachon, Esther A Dempsey, Andreas Dufke, Michael Henri Duyzend, Mirna El Ghosh, Jessica L Giordano, Ragnhild Glad, Ieva Grinfelde, Dominic G Iliescu, Markus S Ladewig, Monica C Munoz-Torres, Marzia Pollazzon, Francesca Clementina Radio, Carlota Rodo, Raquel Gouveia Silva, Damian Smedley, Jagadish Chandrabose Sundaramurthi, Sabrina Toro, Irene Valenzuela, Nicole A Vasilevsky, Ronald J Wapner, Roni Zemet, Melissa A Haendel, and Peter N Robinson

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    Priorities to Promote Participant Engagement in the Participant Engagement and Cancer Genome Sequencing (PE-CGS) Network., Anne Lr Schuster, Norah L Crossnohere, Melinda Bachini, Cindy K Blair, John D Carpten, Elizabeth B Claus, Graham A Colditz, Li Ding, Bettina F Drake, Ryan C Fields, Katherine A Janeway, Bethany M Kwan, Heinz-Josef Lenz, Qin Ma, Shiraz I Mishra, Electra D Paskett, Timothy R Rebbeck, Charité Ricker, Mariana C Stern, Andrew L Sussman, Jessica C Tiner, Jeffrey M Trent, Roel G W Verhaak, Nikhil Wagle, Cheryl Willman, and John Fp Bridges

     

    Profiling Genomic Diversity in a New Wild Mouse Strain Resource, Gabriel McMillen

     

    Profiling the transposable element landscape in a new wild mouse resource, Sirohi Kumar

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    Promoting validation and cross-phylogenetic integration in model organism research., Keith C Cheng, Rebecca D Burdine, Mary E Dickinson, Stephen C Ekker, Alex Y Lin, K C Kent Lloyd, Cathleen Lutz, Calum A MacRae, John H Morrison, David H O'Connor, John H Postlethwait, Crystal D Rogers, Susan Sanchez, Julie H Simpson, William S Talbot, Douglas C Wallace, Jill M Weimer, and Hugo J Bellen

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    Protein coding variation in the J:ARC and J:DO outbred laboratory mouse stocks provides a molecular basis for distinct research applications., Belinda Cornes, Carolyn Paisie, Emily Swanzey, Peter D Fields, Andrew Schile, Kelly Brackett, Laura G Reinholdt, and Anuj Srivastava

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    Pten inhibition dedifferentiates long-distance axon-regenerating intrinsically photosensitive retinal ganglion cells and upregulates mitochondria-associated Dynlt1a and Lars2., Bruce A Rheaume, Jian Xing, Agnieszka Lukomska, William C Theune, Ashiti Damania, Greg Sjogren, and Ephraim F Trakhtenberg

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    PTS is activated by ATF4 and promotes lung adenocarcinoma development via the Wnt pathway, Wei Ma, Chao Wang, Ruzhen Li, Zhaohui Han, Yuanzhu Jiang, Xiangwei Zhang, Duilio Divisi, Enrico Capobianco, Lin Zhang, and Wei Dong

     

    Quantifying the spatial relationship between PORCN and JAG1 in the Mouse Cochlea, Emily Burt

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    Rapid Evolution of the Fine-scale Recombination Landscape in Wild House Mouse (Mus musculus) Populations., Lydia K Wooldridge and Beth L Dumont

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    [Rare-disease data standards]., Peter N Robinson and Holm Graessner

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    Rate of tau propagation is a heritable disease trait in genetically diverse mouse strains., Lindsay A Welikovitch, Simon Dujardin, Amy R Dunn, Analiese R Fernandes, Anita Khasnavis, Lori B Chibnik, Catherine Kaczorowski, and Bradley T Hyman

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    Reduction in GABAB on glia induce Alzheimer's disease related changes., Amanda M Leisgang Osse, Ravi S Pandey, Ryan A Wirt, Andrew A Ortiz, Arnold Salazar, Michael Kimmich, Erin N Toledano Strom, Adrian Oblak, Bruce Lamb, James M Hyman, Gregory W. Carter, and Jefferson Kinney

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    Reduction of Paraoxonase Expression Followed by Inactivation across Independent Semiaquatic Mammals Suggests Stepwise Path to Pseudogenization., Allie M Graham, Jerrica M Jamison, Marisol Bustos, Charlotte Cournoyer, Alexa Michaels, Jason S Presnell, Rebecca Richter, Daniel E Crocker, Ari Fustukjian, Margaret E Hunter, Lorrie D Rea, Judit Marsillach, Clement E Furlong, Wynn K Meyer, and Nathan L Clark

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    Regulation of protein abundance in genetically diverse mouse populations., Gregory R Keele, Tian Zhang, Duy T. Pham, Matthew J Vincent, Timothy A Bell, Pablo Hock, Ginger D Shaw, Joao A Paulo, Steven C. Munger, Fernando Pardo-Manuel de Villena, Martin T Ferris, Steven P Gygi, and Gary Churchill

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    Repeated dosing with cocaine produces strain-dependent effects on responding for conditioned reinforcement in Collaborative Cross mice., Lauren S Bailey, Jared R Bagley, James D Wherry, Elissa J Chesler, Anushree Karkhanis, James D Jentsch, and Lisa M Tarantino

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    Reproductive genomics of the mouse: implications for human fertility and infertility., Alexis Garretson, Beth L Dumont, and Mary Ann Handel

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    Research Note: Association of single nucleotide polymorphism of AKT3 with egg production traits in White Muscovy ducks (Cairina moschata)., Semiu Folaniyi Bello, Haiping Xu, Kan Li, Lijin Guo, Siyu Zhang, Ridwan Olawale Ahmed, Endashaw Jebessa Bekele, Ming Zheng, Mingjian Xian, Bahareldin Ali Abdalla, Adeniyi Charles Adeola, Adeyinka Abiola Adetula, Raman Akinyanju Lawal, Weijian Zhu, Dexiang Zhang, Xiquan Zhang, Congliang Ji, and Qinghua Nie

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    Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements., Ardian Ferraj, Peter A Audano, Parithi Balachandran, Anne M Czechanski, Jacob I Flores, Alexander A Radecki, Varun Mosur, David S Gordon, Isha A Walawalkar, Evan E Eichler, Laura G Reinholdt, and Christine R Beck

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    RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells., Anil Akturk, Matthew Day, and Basile Tarchini

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    R-Loop Formation in Meiosis: Roles in Meiotic Transcription-Associated DNA Damage., Yasuhiro Fujiwara, Mary Ann Handel, and Yuki Okada

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    RNA splicing dysregulation and the hallmarks of cancer., Robert K Bradley and Olga Anczuków

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    Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes., Fangming Xie, Ethan J Armand, Zizhen Yao, Hanqing Liu, Anna Bartlett, M Margarita Behrens, Yang Eric Li, Jacinta D Lucero, Chongyuan Luo, Joseph R Nery, Antonio Pinto-Duarte, Olivier B Poirion, Sebastian Preissl, Angeline C Rivkin, Bosiljka Tasic, Hongkui Zeng, Bing Ren, Joseph R Ecker, and Eran A Mukamel

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    Robustness of single-cell RNA-seq for identifying differentially expressed genes., Yong Liu, Jing Huang, Rajan Pandey, Pengyuan Liu, Bhavika Therani, Qiongzi Qiu, Sridhar Rao, Aron M Geurts, Allen W Cowley, Andrew S Greene, and Mingyu Liang

     

    Role of Flial Cells in the Arcuate Nucleus of the Hypothalamus in High-Fat Diet Consuming Mice, Hunter Samuel

     

    Role of srGAP3 protein stability in mediating voluntary cocaine abuse in Gridlock'd mutant mice, Elaina Cote

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    Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression., Qing Yu, Xinyue Liu, Mark P Keller, Jose Navarrete-Perea, Tian Zhang, Sipei Fu, Laura P Vaites, Steven R Shuken, Ernst Schmid, Gregory R Keele, Jiaming Li, Edward L Huttlin, Edrees H Rashan, Judith Simcox, Gary Churchill, Devin K Schweppe, Alan D Attie, Joao A Paulo, and Steven P Gygi

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    SEESAW: detecting isoform-level allelic imbalance accounting for inferential uncertainty., Euphy Y Wu, Noor P Singh, Kwangbom Choi, Mohsen Zakeri, Matthew J Vincent, Gary Churchill, Cheryl L Ackert-Bicknell, Rob Patro, and Michael I Love

     

    Selective ablation of the ELF3 transcription factor and its effects on trophoblast stem cell, syncytiotrophoblast, and primitive syncytium differentiation, Carla D'Amato

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    Sequencing and assembling bear genomes: the bare necessities., Courtney Willey and Ron Korstanje

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    Seven days in the life cycle of Homo sapiens., Martin Pera

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    Seven naturally variant loci serve as genetic modifiers of Lamc2jeb induced non-Herlitz junctional Epidermolysis Bullosa in mice., Thomas J. Sproule, Vivek M. Philip, Nabig A Chaudhry, Derry C. Roopenian, and John P Sundberg

     

    Sex- and age-dependent genetics of longevity in a heterogeneous mouse population., Maroun Bou Sleiman, Suheeta Roy, Arwen W Gao, Marie C Sadler, Giacomo V G von Alvensleben, Hao Li, Saunak Sen, David E Harrison, James F Nelson, Randy Strong, Richard A Miller, Zoltán Kutalik, Robert W Williams, and Johan Auwerx

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    Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice., Brigitte E Martin, Erin B Taylor, Esinam M Attipoe, Wenjie Wu, David E Stec, Kurt C Showmaker, and Michael R Garrett

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    Sex-specific role of myostatin signaling in neonatal muscle growth, denervation atrophy, and neuromuscular contractures., Marianne E Emmert, Parul Aggarwal, Kritton Shay-Winkler, Se-Jin Lee, Qingnian Goh, and Roger Cornwall

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    Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model., Jiwon Yang, Jing Jiao, Kyle Draheim, Guoxiang Yang, Hongyuan Yang, Li-Chin Yao, Leonard D. Shultz, Dale L Greiner, Deepa Rajagopal, Sandrine Vessillier, Curtis C Maier, Sunish Mohanan, Danying Cai, Mingshan Cheng, Michael A Brehm, and James G. Keck

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    Simultaneous multifunctional transcriptome engineering by CRISPR RNA scaffold., Zukai Liu, Nathaniel L. Jillette, Paul Robson, and Albert Cheng

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    Single-Cell RNA Sequencing Reveals Molecular Features of Heterogeneity in the Murine Retinal Pigment Epithelium., Ravi S Pandey, Mark P. Krebs, Mohan Bolisetty, Jeremy R. Charette, Juergen K. Naggert, Paul Robson, Patsy M. Nishina, and Gregory W. Carter

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    Single-Cell Transcriptome Analysis Defines Expression of Kabuki Syndrome-Associated KMT2D Targets and Interacting Partners., Badam Enkhmandakh, Paul Robson, Pujan Joshi, Anushree Vijaykumar, Dong-Guk Shin, Mina Mina, and Dashzeveg Bayarsaihan

     

    Single-cell transcriptomics defines Dot1L interacting partners and downstream target genes in the mouse molar dental pulp., Rosa Guzzo, Badam Enkhmandakh, Timothy Becker, Pujan Joshi, Paul Robson, Anushree Vijaykumar, Mina Mina, Dong-Guk Shin, and Dashzeveg Bayarsaihan

     

    Single-nucleus Transcriptome Profiling of Cancer-associated Fibroblasts in Glioma, Andreas Stephanou

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    Skin Extracellular Matrix Breakdown Following Paclitaxel Therapy in Patients with Chemotherapy-Induced Peripheral Neuropathy., Nathan P Staff, Sybil C Hrstka, Surendra Dasari, Enrico Capobianco, and Sandra Rieger

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    Skin, Hair, and Nails, John P Sundberg, Lloyd E. King Jr, and Raoul V. Kuiper

     

    Skin microbiome attributes associate with biophysical skin ageing., Wei Zhou, Elizabeth Fleming, Guylaine Legendre, Lauriane Roux, Julie Latreille, Gaëlle Gendronneau, Sandra Forestier, and Julia Oh

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    Spatial mapping of cellular senescence: emerging challenges and opportunities., Aditi U Gurkar, Akos A Gerencser, Ana L Mora, Andrew C Nelson, Anru R Zhang, Anthony B Lagnado, Archibald Enninful, Christopher Benz, David Furman, Delphine Beaulieu, Diana Jurk, Elizabeth L Thompson, Fei Wu, Fernanda Rodriguez, Grant Barthel, Hao Chen, Hemali Phatnani, Indra Heckenbach, Jeffrey Chuang, Jeremy Horrell, Joana Petrescu, Jonathan K Alder, Jun Hee Lee, Laura J Niedernhofer, Manoj Kumar, Melanie Königshoff, Marta Bueno, Miiko Sokka, Morten Scheibye-Knudsen, Nicola Neretti, Oliver Eickelberg, Peter D Adams, Qianjiang Hu, Quan Zhu, Rebecca A Porritt, Runze Dong, Samuel Peters, Stella Victorelli, Thomas Pengo, Timur Khaliullin, Vidyani Suryadevara, Xiaonan Fu, Ziv Bar-Joseph, Zhicheng Ji, and João F Passos

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    Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia., Diana Cadena, Sonia Jangra, Marina Yurieva, Jan Martinek, Megan Callender, Matthew Coxe, Angela Choi, Juan García-Bernalt Diego, Jianan Lin, Te-Chia Wu, Florentina Marches, Damien Chaussabel, Peter Yu, Andrew Salner, Gabrielle Aucello, Jonathan Koff, Briana Hudson, Sarah E Church, Kara Gorman, Esperanza Anguiano, Adolfo García-Sastre, Adam Williams, Michael Schotsaert, and Karolina Palucka

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    Statistical Learning Methods to Identify Nonwear Periods From Accelerometer Data, Sahrej Randhawa, Manoj Sharma, Madalina Fiterau, Jorge A. Banda, Farish Haydel, Kristopher Kapphahn, Donna Matheson, Hyatt Moore IV, Robyn L Ball, Clete Kushida, Scott Delp, Dennis P. Wall, Thomas Robinson, and Manisha Desai

     

    Strains to go: interactions of the skin microbiome beyond its species., Ryan Caldwell, Wei Zhou, and Julia Oh

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    Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma., Wajd N Al-Holou, Hanxiao Wang, Visweswaran Ravikumar, Sunita Shankar, Morgan Oneka, Ziad Fehmi, Roel G W Verhaak, Hoon Kim, Drew Pratt, Sandra Camelo-Piragua, Corey Speers, Daniel R Wahl, Todd Hollon, Oren Sagher, Jason A Heth, Karin M Muraszko, Theodore S Lawrence, Ana C de Carvalho, Tom Mikkelsen, Arvind Rao, and Alnawaz Rehemtulla

     

    SVision: a deep learning approach to resolve complex structural variants., Jiadong Lin, Songbo Wang, Peter A Audano, Deyu Meng, Jacob I Flores, Walter Kosters, Xiaofei Yang, Peng Jia, Tobias Marschall, Christine R Beck, and Kai Ye

     

    Targeting gene fusions as a therapeutic approach in pediatric cancers, Elisa Saint-Denis

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    Targeting SARS-CoV-2 infection through CAR-T-like bispecific T cell engagers incorporating ACE2., Mikail Dogan, Lina Kozhaya, Lindsey Placek, Fatih Karabacak, Mesut Yigit, and Derya Unutmaz

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    Taxonomic assessment of two wild house mouse subspecies using whole-genome sequencing., Raman Akinyanju Lawal, Verity L Mathis, Mary Barter, Jeremy R. Charette, Alexis Garretson, and Beth L Dumont

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    Temporal Progression of Aortic Valve Pathogenesis in a Mouse Model of Osteogenesis Imperfecta., Kaitlyn Thatcher, Carol R Mattern, Daniel Chaparro, Veronica Goveas, Michael R McDermott, Jessica Fulton, Joshua D Hutcheson, Brian Hoffmann, and Joy Lincoln

     

    Testing the Extent a Chemotherapy is Influenced by Host Genetics, Marianna Ward

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    The 677C > T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice, Alaina M Reagan, Karen E Christensen, Leah C. Graham, Amanda A Bedwell, Kierra Eldridge, Rachael Speedy, Lucas L Figueiredo, Scott C Persohn, Teodoro Bottiglieri, Kwangsik Nho, Michael Sasner, Paul R Territo, Rima Rozen, and Gareth R Howell

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    The case for standardizing gene nomenclature in vertebrates., Fiona M McCarthy, Tamsin E M Jones, Anne E Kwitek, Cynthia Smith, Peter D Vize, Monte Westerfield, and Elspeth A Bruford

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    The collaborative cross strains and their founders vary widely in cocaine-induced behavioral sensitization., Sarah A Schoenrock, Leona H. Gagnon, Ashley A Olson, Michael Leonardo, Vivek M. Philip, Hao He, Laura G. Reinholdt, S J Sukoff Rizzo, James D Jentsch, Elissa J Chesler, and Lisa M Tarantino

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    The consequences of recurrent genetic and epigenetic variants in human pluripotent stem cells., Peter W Andrews, Ivana Barbaric, Nissim Benvenisty, Jonathan S Draper, Tenneille Ludwig, Florian T Merkle, Yoji Sato, Claudia Spits, Glyn N Stacey, Haoyi Wang, and Martin Pera

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    The dark kinase STK32A regulates hair cell planar polarity opposite of EMX2 in the developing mouse inner ear., Shihai Jia, Evan M Ratzan, Ellison J Goodrich, Raisa Abrar, Luke Heiland, Basile Tarchini, and Michael R Deans

     

    The Effect of Allelic Variation on Genetic Recombination and Oocyte Quality, Priya Kosana

     

    The Effect of Genetic Background on Charcot-Marie-Tooth Histopathology in Mice, Lily Moy

     

    The effect of the Arg1956Trp mutation in the IQ3 domain of MYO15A on stereocilia formation and hearing loss, Lilly Krupp

     

    The Effects of Genetic Variation on Acute Myeloid Leukemia Growth in Mice, Dan Bernstein

     

    The Effects of Heterochromatin Formation on 3-D Genome Contacts in Mouse Embryonic Stem Cells, Brooke Wilson

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    The Environmental Conditions, Treatments, and Exposures Ontology (ECTO): connecting toxicology and exposure to human health and beyond., Lauren E Chan, Anne E Thessen, William D Duncan, Nicolas Matentzoglu, Charles Schmitt, Cynthia J Grondin, Nicole Vasilevsky, Julie A McMurry, Peter N Robinson, Christopher J Mungall, and Melissa A Haendel

     

    The Expression of ZFHX4 Protein in Developing Mouse Lungs and Lung Adenocarcinoma, Tina Li

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    The functional and evolutionary impacts of human-specific deletions in conserved elements., James R Xue, Ava Mackay-Smith, Kousuke Mouri, Meilin Fernandez Garcia, Michael X Dong, Jared F Akers, Mark Noble, Xue Li, Zoonomia Consortium, Kerstin Lindblad-Toh, Elinor K Karlsson, James P Noonan, Terence D Capellini, Kristen J Brennand, Ryan Tewhey, Pardis C Sabeti, and Steven K Reilly

     

    The Fungal Microbiome of the Upper Airway Is Associated With Future Loss of Asthma Control and Exacerbation Among Children With Asthma., Hanshu Yuan, Zhongmao Liu, Jinhong Dong, Leonard B Bacharier, Daniel Jackson, David Mauger, Homer Boushey, Mario Castro, Juliana Durack, Yvonne J Huang, Robert F Lemanske, Gregory A Storch, George M. Weinstock, Kristine Wylie, Ronina Covar, Anne M Fitzpatrick, Wanda Phipatanakul, Rachel G Robison, Avraham Beigelman, and Yanjiao Zhou

     

    The Genetics and Evolution of the Thyroid System, C K. Chai

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    The Immune Signatures data resource, a compendium of systems vaccinology datasets., Joann Diray-Arce, Helen E R Miller, Evan Henrich, Bram Gerritsen, Matthew P Mulè, Slim Fourati, Jeremy Gygi, Thomas Hagan, Lewis Tomalin, Dmitry Rychkov, Dmitri Kazmin, Daniel G Chawla, Hailong Meng, Patrick Dunn, John Campbell, the Human Immunology Project Consortium (HIPC), Minnie Sarwal, John S Tsang, Ofer Levy, Bali Pulendran, Rafick Sekaly, Aris Floratos, Raphael Gottardo, Steven H Kleinstein, and Mayte Suárez-Fariñas

     

    The impact of the Y chromosome on the reproductive fitness of male wild-derived mice, Keona Banks

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    The impact of vitamin D on cancer: A mini review., Gerbenn Seraphin, Sandra Rieger, Martin Hewison, Enrico Capobianco, and Thomas S Lisse

     

    The Impact of Zbtb7a and Zbtb7b Loss in Acute Myeloid Leukemia Drug Resistance, Meryl McKenna

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    The Maine Cancer Genomics Initiative: Implementing a Community Cancer Genomics Program Across an Entire Rural State., Jens Rueter, Eric C Anderson, Leah C. Graham, Andrey Antov, Petra Helbig, Lory Gaitor, Jennifer Bourne, Emily A Edelman, Kate Reed, Honey V Reddi, Susan Mockus, John DiPalazzo, Christine Lu-Emerson, Roger Inhorn, Sarah J Sinclair, Christian A Thomas, Philip L Brooks, Karen Rasmussen, Paul Han, Edison Liu, and MCGI Working Group

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    The microbial community dynamics of cocaine sensitization in two behaviorally divergent strains of collaborative cross mice., Thi Dong Binh Tran, Christian Monroy Hernandez, Hoan Nguyen, Susan Wright, Center for Systems Neurogenetics of Addiction, Lisa M Tarantino, Elissa J Chesler, George M. Weinstock, Yanjiao Zhou, and Jason A. Bubier

     

    The Milky Way Project: Multi-omic Clocks of Biological Age and Rates of Aging, Matthew Luchs

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    The Mouse Models of Human Cancer database (MMHCdb)., Dale A. Begley, Debra M Krupke, John P Sundberg, Emily L Jocoy, Joel E Richardson, Steven Neuhauser, and Carol J Bult

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    The Mouse Online: Open Mouse Biology and Pathology Data Resources for Biomedical Research, Dale A. Begley, Paul N. Schofield, and John P Sundberg

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    The Ontology of Biological Attributes (OBA)-computational traits for the life sciences., Ray Stefancsik, James P Balhoff, Meghan A Balk, Robyn L Ball, Susan M. Bello, Anita R Caron, Elissa J Chesler, Vinicius de Souza, Sarah Gehrke, Melissa Haendel, Laura W Harris, Nomi L Harris, Arwa Ibrahim, Sebastian Koehler, Nicolas Matentzoglu, Julie A McMurry, Christopher J Mungall, Monica C Munoz-Torres, Tim Putman, Peter N Robinson, Damian Smedley, Elliot Sollis, Anne E Thessen, Nicole Vasilevsky, David O Walton, and David Osumi-Sutherland

     

    The Precision Toxicology initiative., PrecisionTox Consortium

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    The RNA-binding protein FUS/TLS interacts with SPO11 and PRDM9 and localize at meiotic recombination hotspots., Teresa Giannattasio, Erika Testa, Ramona Palombo, Lidia Chellini, Flavia Franceschini, Álvaro Crevenna, Petko M. Petkov, Maria Paola Paronetto, and Marco Barchi

     

    The role of EPASI, an oxygen-sensing transcription facor, in trophoblast differentiation, Braeden Rose

     

    The Role of FAS Receptor Methylation in Osteosarcoma Metastasis., Jiayi M Sun, Wing-Yuk Chow, Gufeng Xu, M John Hicks, Manjula Nakka, Jianhe Shen, Patrick Ks Ng, Aaron M Taylor, Alexander Yu, Jason E Farrar, Donald A Barkauskas, Richard Gorlick, Jaime M Guidry Auvil, Daniela Gerhard, Paul Meltzer, Rudy Guerra, Tsz-Kwong Man, Ching C Lau, and On Behalf Of The Target Osteosarcoma Consortium

     

    The role of Oit3 in embryonic development, Lenka Slamova

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    The RSNA Cervical Spine Fracture CT Dataset., Hui Ming Lin, Errol Colak, Tyler Richards, Felipe C Kitamura, Luciano M Prevedello, Jason Talbott, Robyn L Ball, Ekim Gumeler, Kristen W Yeom, Mohammad Hamghalam, Amber L Simpson, Jasna Strika, Deniz Bulja, Salita Angkurawaranon, Almudena Pérez-Lara, María Isabel Gómez-Alonso, Johanna Ortiz Jiménez, Jacob J Peoples, Meng Law, Hakan Dogan, Emre Altinmakas, Ayda Youssef, Yasser Mahfouz, Jayashree Kalpathy-Cramer, Adam E Flanders, and RSNA-ASSR-ASNRAnnotatorsandtheDataset Curation Contributors

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    The spontaneous mouse mutant low set ears (Lse) is caused by tandem duplication of Fgf3 and Fgf4., Alana Luzzio, Sarah Edie, Kristina Palmer, L Brianna Caddle, Rachel Urban, Leslie Goodwin, Ian C Welsh, Laura G Reinholdt, David E. Bergstrom, Timothy C Cox, Leah Rae Donahue, and Stephen A. Murray

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    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina., Mathilde Pruvost, Julia Patzig, Camila Yattah, Ipek Selcen, Marylens Hernandez, Hye-Jin Park, Sarah Moyon, Shibo Liu, Malia S Morioka, Lindsay S. Shopland, Osama Al-Dalahmah, Jaroslav Bendl, John F Fullard, Panos Roussos, James Goldman, Ye He, Jeffrey L Dupree, and Patrizia Casaccia

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    The study of selection signature and its applications on identification of candidate genes using whole genome sequencing data in chicken-a review., Semiu Folaniyi Bello, Raman Akinyanju Lawal, Adeniyi Charles Adeola, and Qinghua Nie

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    The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways., Parakkal Jovvian George, Radu Marches, Djamel Nehar-Belaid, Jacques Banchereau, and Sara Lustigman

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    The trouble with triples: Examining the impact of measurement error in mediation analysis., Madeleine S Gastonguay, Gregory R Keele, and Gary Churchill

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    TMEM161B modulates radial glial scaffolding in neocortical development., Lu Wang, Caleb Heffner, Keng Ioi Vong, Chelsea Barrows, Yoo-Jin Ha, Sangmoon Lee, Pablo Lara-Gonzalez, Ishani Jhamb, Dennis Van Der Meer, Robert Loughnan, Nadine Parker, David Sievert, Swapnil Mittal, Mahmoud Y Issa, Ole A Andreassen, Anders Dale, William B Dobyns, Maha S Zaki, Stephen A Murray, and Joseph G Gleeson

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    TNBC Therapeutics Based on Combination of Fusarochromanone with EGFR Inhibitors., Natalie Carroll, Reneau Youngblood, Alena Smith, Ana-Maria Dragoi, Brian A Salvatore, and Elahe Mahdavian

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    Trackable and scalable LC-MS metabolomics data processing using asari., Shuzhao Li, Amnah Siddiqa, Maheshwor Thapa, Yuanye Chi, and Shujian Zheng

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    Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging., Emin Onur Karakaslar, Neerja Katiyar, Muneer G. Hasham, Ahrim Youn, Siddhartha Sharma, Cheng-Han Chung, Radu Marches, Ron Korstanje, Jacques Banchereau, and Duygu Ucar

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    Transcriptional and Translational Dynamics of Zika and Dengue Virus Infection., Kamini Singh, Maria Guadalupe Martinez, Jianan Lin, James Gregory, Trang Uyen Nguyen, Rawan Abdelaal, Kristy Kang, Kristen Brennand, Arnold Grünweller, Zhengqing Ouyang, Hemali Phatnani, Margaret Kielian, and Hans-Guido Wendel

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    Transcriptomic responses in the blood and sputum of cigarette smokers compared to e-cigarette vapers., Mario F Perez, Marina Yurieva, Spandana Poddutoori, Eric M Mortensen, Laura E Crotty Alexander, and Adam Williams

     

    Transfer learning of a multitask deep neural network to predict enhancer activity of regulatory variants in the HCT116 cell-line, Frank Liu

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    Translating Data Science Results into Precision Oncology Decisions: A Mini Review., Enrico Capobianco and Marco Dominietto

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    Translocation and metabolism of tricresyl phosphate in rice and microbiome system: Isomer-specific processes and overlooked metabolites., Yuanyuan Yu, Jiahui Huang, Ling Jin, Miao Yu, Xiaolong Yu, Xifen Zhu, Jianteng Sun, and Lizhong Zhu

     

    Translocation detection from Hi-C data via scan statistics., Anthony Cheng, Disheng Mao, Yuping Zhang, Joseph Glaz, and Zhengqing Ouyang

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    Transposable element-mediated rearrangements are prevalent in human genomes., Parithi Balachandran, Isha A Walawalkar, Jacob I Flores, Jacob N Dayton, Peter A Audano, and Christine R Beck

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    Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development., Cayla E Jewett, Bailey L McCurdy, Eileen T O'Toole, Alexander J Stemm-Wolf, Katherine S Given, Carrie H Lin, Valerie Olsen, Whitney Martin, Laura G Reinholdt, Joaquín M Espinosa, Kelly D Sullivan, Wendy B Macklin, Rytis Prekeris, and Chad G Pearson

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    tRNA Dysregulation in Neurodevelopmental and Neurodegenerative Diseases., Robert W. Burgess and Erik Storkebaum

     

    Two new mouse models of Gjb1-associated Charcot-Marie-Tooth disease type 1X., A L D Tadenev, C L Hatton, B Pattavina, T Mullins, Robert Schneider, Laurent P. Bogdanik, and Robert W. Burgess

     

    Uncovering transcriptional changesrelated to cisplatin treatment andmixing of TNBC subclones usingsingle-cell RNA sequencing, Shadae Nicholas

     

    Unraveling the Role of Glycolysis-Derived Pyruvate in Modulation of TIM-3 Expression in Cancer, Chloe Ledford

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    Urban-Rural and Socioeconomic Differences in Patient Knowledge and Perceptions of Genomic Tumor Testing., Jessica F DiBiase, Elizabeth Scharnetzki, Emily A Edelman, F Lee Lucas, Petra Helbig, Jens Rueter, Paul K J Han, Erika Ziller, Elizabeth A Jacobs, and Eric C Anderson

     

    Using Machine-Vision to Quantify Mouse Behavior, Joseph DuPree

     

    Using Modified Bacterial Artificial Chromosomes to Develop Transgenic Mouse Models Containing Human Genes with Disease Causing Mutations, Srilekha Kadimi

     

    Using the Collaborative Cross to identify putative gamete compatibility genes, Clare Mulcahy

     

    Utilizing CRISPR technologies to probe Staphylococcus epidermidis' role in the human skin microbiome, Destiny Porter

     

    V225G Mutation Increases Stability of KPNA3 Thereby Contributing to an Age-Dependent Hyperactive Phenotype in C57BL/6J Mice, Ryan Guardado

     

    Variant Caller Performance on Diverse Strains: Exploring the significance of the reference genome on caller performance, Aleisha Roberts

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    Variation in histone configurations correlates with gene expression across nine inbred strains of mice., Anna L. Tyler, Catrina Spruce, Romy Kursawe, Annat Haber, Robyn L Ball, Wendy A Pitman, Alexander D Fine, Narayanan Raghupathy, Michael Walker, Vivek M. Philip, Christopher L. Baker, J Matthew Mahoney, Gary Churchill, Jennifer J. Trowbridge, Michael L. Stitzel, Kenneth Paigen, Petko M. Petkov, and Gregory W. Carter

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    Variation in the CENP-A sequence association landscape across diverse inbred mouse strains., Uma P Arora, Beth A Sullivan, and Beth L Dumont

     

    Visual Prediction of Mouse Mass using Machine Learning, Malachy Guzman

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    Vitamin D inhibits osteosarcoma by reprogramming nonsense-mediated RNA decay and SNAI2-mediated epithelial-to-mesenchymal transition., Enrico Capobianco, Vanessa McGaughey, Gerbenn Seraphin, John Heckel, Sandra Rieger, and Thomas S Lisse

     

    Weighted learning for long-read DNA sequencing consensus methylation detection, Emma Wade

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    What Makes a Functional Gene Regulatory Network? A Circuit Motif Analysis., Lijia Huang, Benjamin Clauss, and Mingyang Lu

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    Which mouse multiparental population is right for your study? The Collaborative Cross inbred strains, their F1 hybrids, or the Diversity Outbred population., Gregory R Keele

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    Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity., Kevin A Peterson, Sam Khalouei, Nour Hanafi, Joshua A Wood, Denise G Lanza, Lauri G Lintott, Brandon J Willis, John R Seavitt, Robert E Braun, Mary E Dickinson, Jacqueline K White, K C Kent Lloyd, Jason D Heaney, Stephen A. Murray, Arun Ramani, and Lauryl M J Nutter

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    Whole-genome functional characterization of RE1 silencers using a modified massively parallel reporter assay., Kousuke Mouri, Hannah B Dewey, Rodrigo Castro, Daniel Berenzy, Susan Kales, and Ryan Tewhey

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    Whole Genome Resequencing Reveals Genetic Diversity and Selection Signatures of Ethiopian Indigenous Cattle Adapted to Local Environments, Endashaw Terefe, Gurja Belay, Abdulfatai Tijjani, Jianlin Han, and Oliver Hanotte

     

    Why it is important to study human-monkey embryonic chimeras in a dish., Alejandro De Los Angeles, Alan Regenberg, Victoria Mascetti, Nissim Benvenisty, George Church, Hongkui Deng, Juan Carlos Izpisua Belmonte, Weizhi Ji, Julian Koplin, Yuin-Han Loh, Yuyu Niu, Duanqing Pei, Martin Pera, Nam Pho, Carlos Pinzon-Arteaga, Mitinori Saitou, Jose C R Silva, Tan Tao, Alan Trounson, Tushar Warrier, and Elias T Zambidis

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    Widespread perturbation of ETS factor binding sites in cancer., Sebastian Carrasco Pro, Heather Hook, David Bray, Daniel Berenzy, Devlin Moyer, Meimei Yin, Adam Thomas Labadorf, Ryan Tewhey, Trevor Siggers, and Juan Ignacio Fuxman Bass

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    Witch Nails (Krt90whnl): A spontaneous mouse mutation affecting nail growth and development., John P Sundberg, Hannah Galantino-Homer, Heather Fairfield, Patricia F. Ward-Bailey, Belinda S. Harris, Melissa L. Berry, C Herbert Pratt, Nicholas E Gott, Lesley S Bechtold, Pauline R Kaplan, Blythe P Durbin-Johnson, David M Rocke, and Robert H Rice

 
 
 

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